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Re: Associations between Physical Activity and Semen Quality in Young Healthy Men
MALE INFERTILITY
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Re: Moderate Aerobic Exercise Training for Improving Reproductive Function in Infertile Patients: A Randomized Controlled Trial B. Hajizadeh Maleki and B. Tartibian Department of Sports Medicine, Justus-Liebig-University, Giessen, Germany, and Department of Sport Injuries, Faculty of Physical Education and Sport Sciences, Allameh Tabataba’i University, Tehran, Iran Cytokine 2017; 92: 55e67. doi: 10.1016/j.cyto.2017.01.007
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/28092795 Editorial Comment: In this large, randomized, controlled, partial crossover study the researchers divided men with infertility into 2 groups, those who were instructed not to exercise and those placed on a verifiable aerobic exercise regimen for up to 24 weeks. Interestingly they chose to exclude men with endocrine abnormalities, thus focusing on idiopathic infertility. In the group that exercised the authors observed improvement in a variety of sperm oxidative stress and inflammation assays, sperm DNA integrity, bulk seminal parameters and pregnancy outcomes. A 4-week period after the exercise program where men returned to a sedentary lifestyle did not return the improvements to baseline. This is a detailed study with a design that is about as good as it can be, and it indicates a beneficial effect of aerobic exercise on male reproduction. With so many general health benefits for aerobic exercise urologists can encourage sedentary men with infertility to get up off the couch. Craig Niederberger, MD
Re: Associations between Physical Activity and Semen Quality in Young Healthy Men zko w, M. Me˛dra ska-Lisowska P. Jo s, F. Lwow, A. Zagrodna and M. S1owin Departments of Sports Medicine, Health Promotion and Nutrition, University School of Physical Education and Department of Endocrinology, Diabetology and Isotope Treatment, Wroclaw Medical University, Wrocław, Poland Fertil Steril 2017; 107: 373e378.e2. doi: 10.1016/j.fertnstert.2016.11.004
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27919439 Editorial Comment: In this cross-sectional analysis the researchers compared sperm parameters of healthy young men according to how physically active they were. Importantly these men were not identified as infertile. Surprisingly the more active men had more immotile sperm in their ejaculates than less active men. However, the overall amount of motile sperm in bulk seminal parameters of all groups was well into the fertile range. What is best gleaned from this study is that the relationship between physical activity and sperm is likely related to the underlying physiology of the individual, and quite possibly to whether the individual is infertile and why. In the meantime advising men to exercise sensibly remains a good idea. Craig Niederberger, MD
Re: Men’s Knowledge of Their Own Fertility: A Population-Based Survey Examining the Awareness of Factors that are Associated with Male Infertility D. Daumler, P. Chan, K. C. Lo, J. Takefman and P. Zelkowitz Department of Psychiatry and Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Urology, McGill Reproductive Centre, McGill University Health Centre and Department of Psychiatry, McGill University, Montreal, Quebec and Department of Urology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada Hum Reprod 2016; 31: 2781e2790. doi: 10.1093/humrep/dew265
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27816924 Editorial Comment: These investigators administered a Web based questionnaire to Canadian men inquiring about knowledge of fixed and modifiable risk factors in male infertility, such as cancer,
241
Re: Moderate Aerobic Exercise Training for Improving Reproductive Function in Infertile Patients: A Randomized Controlled Trial B. Hajizadeh Maleki and B. Tartibian Department of Sports Medicine, Justus-Liebig-University, Giessen, Germany, and Department of Sport Injuries, Faculty of Physical Education and Sport Sciences, Allameh Tabataba’i University, Tehran, Iran Cytokine 2017; 92: 55e67. doi: 10.1016/j.cyto.2017.01.007
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/28092795 Editorial Comment: In this large, randomized, controlled, partial crossover study the researchers divided men with infertility into 2 groups, those who were instructed not to exercise and those placed on a verifiable aerobic exercise regimen for up to 24 weeks. Interestingly they chose to exclude men with endocrine abnormalities, thus focusing on idiopathic infertility. In the group that exercised the authors observed improvement in a variety of sperm oxidative stress and inflammation assays, sperm DNA integrity, bulk seminal parameters and pregnancy outcomes. A 4-week period after the exercise program where men returned to a sedentary lifestyle did not return the improvements to baseline. This is a detailed study with a design that is about as good as it can be, and it indicates a beneficial effect of aerobic exercise on male reproduction. With so many general health benefits for aerobic exercise urologists can encourage sedentary men with infertility to get up off the couch. Craig Niederberger, MD
Re: Associations between Physical Activity and Semen Quality in Young Healthy Men zko w, M. Me˛dra ska-Lisowska P. Jo s, F. Lwow, A. Zagrodna and M. S1owin Departments of Sports Medicine, Health Promotion and Nutrition, University School of Physical Education and Department of Endocrinology, Diabetology and Isotope Treatment, Wroclaw Medical University, Wrocław, Poland Fertil Steril 2017; 107: 373e378.e2. doi: 10.1016/j.fertnstert.2016.11.004
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27919439 Editorial Comment: In this cross-sectional analysis the researchers compared sperm parameters of healthy young men according to how physically active they were. Importantly these men were not identified as infertile. Surprisingly the more active men had more immotile sperm in their ejaculates than less active men. However, the overall amount of motile sperm in bulk seminal parameters of all groups was well into the fertile range. What is best gleaned from this study is that the relationship between physical activity and sperm is likely related to the underlying physiology of the individual, and quite possibly to whether the individual is infertile and why. In the meantime advising men to exercise sensibly remains a good idea. Craig Niederberger, MD
Re: Men’s Knowledge of Their Own Fertility: A Population-Based Survey Examining the Awareness of Factors that are Associated with Male Infertility D. Daumler, P. Chan, K. C. Lo, J. Takefman and P. Zelkowitz Department of Psychiatry and Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Urology, McGill Reproductive Centre, McGill University Health Centre and Department of Psychiatry, McGill University, Montreal, Quebec and Department of Urology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada Hum Reprod 2016; 31: 2781e2790. doi: 10.1093/humrep/dew265
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27816924 Editorial Comment: These investigators administered a Web based questionnaire to Canadian men inquiring about knowledge of fixed and modifiable risk factors in male infertility, such as cancer,