Advnces in enzymology and related subjects of biochemistry. Vol. XV. Edited by F. F. Nord. Interscience Publishers, Inc., New York, 1954. 547 pp. 16.5 × 24 cm. Price $11

Advnces in enzymology and related subjects of biochemistry. Vol. XV. Edited by F. F. Nord. Interscience Publishers, Inc., New York, 1954. 547 pp. 16.5 × 24 cm. Price $11

October, 1954 SCIENTIFICEDITION and graphs for the effective, condensed presentation of therapeutic indications and results, and for the demonstrati...

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October, 1954

SCIENTIFICEDITION

and graphs for the effective, condensed presentation of therapeutic indications and results, and for the demonstration of characteristic properties such as tolerance, stability, solubility, dosage forms, etc. The bibliographies at the end of each chapter include all pertinent material published as late as 1953.

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providing a n almost unlimited source of information on the subject matter included in this volume. The chapters by the contributors from France and Germany are in the French and German languages, respectively.

Statistical Analysis i n Chemistry and the Chemical L. Industry. By CARLA. BENNETTand NORMAN FRANKLIN. (Sponsored by The Committee on Principles and Practice of Antibiotic Therapy.Applied Mathematical Statistics, The National By HENRY WELCH. Medical Encyclopedia, Inc., Research Council.) John Wiley & Sons, Inc., 699 pp. 15 x 22 cm. New York, 1954. xix New York (Chapman & Hall, Ltd., London), Price $12. 1954. xvi 724 pp. 16 x 23.7 cm. Price $8. The author of this comprehensive work is emiModern statistical methods in chemistry are being nently qualified t o discuss the field of antibiotics. He has been closely connected with the field from used more extensively during the past few years its inception and is now the Chief of the Division of and it was this increasing interest that prompted the Committee on Applied Mathematical Statistics Antibiotics of the U. S. Food and Drug Administration, as well as editor-in-chief of the Journal, Anti- of the National Research Council to decide that a biotics and Chemotherapy. The book is conveniently comprehensive book on applied mathematical statisdivided into two parts, the first of which is con- tics with illustrative examples and material from cerned with the isolation and development, the anti- chemistry and the chemical industry should be microbial activity and the pharmacology of the anti- prepared under the direction of the Committee. biotics, while the second part is devoted t o the The two authors are “a mathematical statistician clinical uses and sub-divided according t o disease with some knowledge of chemistry and a chemist entities. Each chapter contains a selected bibli- with some knowledge of mathematical statistics,” ography and there is a satisfactory index. This book and each has had considerable experience in the can be recommended as the most up t o date and application of statistical methods t o problems in the complete volume on antibiotics at present available field of chemistry. The book deals mainly with the class of statistical in the English language. methods t h a t involve inferences and the first five chapters are used for developing the basic principles Chemotherapy of Infections. By H. 0. J. COLLIER. of this approach. In the remainder of the book John Wiley & Sons, Inc., New York, 1954. xvi are found the more specialized methods for the 248 pp. Illustrated. 14.5 x 19.5 cm. Price industrial problems that seem t o be of greatest $4. importance. For the understanding of the statistical techniques The chemotherapy of parasitic infections, caused by protozoa, bacteria, and rickettsias, but not by presented, sufficient mathematical background, not parasitic worms or viruses, and different chemo- above the level of the engineering or chemistry therapeutic agents are discussed by the author. graduate, is given and examples taken from the About one-third of the book is taken up with such industrial field are used to illustrate the application of topics as microbial attack and body defenses, the the methods. Thus this book can be a comprehensiproblem of getting the chemical t o the microbe ble and valuable aid t o those in chemistry and allied mechanism faction of antimicrobial substances, and industries. The authors state that this book could also be used as a textbook for upper class or graduate drug resistances. Then penicillin, streptomycin, neomycin, and viomycin are briefly discussed and students in statistics. References t o original papers one chapter more or less routinely deals with the from which examples were selected are included at sulfonamides. Tuberculosis, leprosy, some tropical the end of the book. diseases, and the malarias are the only diseases for which the chemotherapy was outlined, these being Vegetable Tanning Materials. By F. N. HOWES. contained in less than forty pages at the end of the Butterworths Scientific Publications, Ltd., book. Chemotherapy of Infections is a rather London, 1953. (American Distributor: The routine review of the literature and may prove useful Chronica Botanica Co., Waltham, Mass.) 325 for this purpose. pp. Illustrated. 14.5 x 22 cm. Price $5.50.

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Advances in Enzymology and Related Subjects of Biochemistry. Vol. XV. Edited by F. F. NORD. Interscience Publishers, Inc., New York, 1954. 547 pp. 16.5 x 24 cm. Price $11. Contributions t o Vol. XV are from institutions in England, Germany, Japan, Australia, and France, as well as in this country. The contents include topics on mechanism of various enzyme actions, urea synthesis, the thermodynamics of immunological reactions, the citric acid cycle, the structure of the tobacco mosaic virus, and other subjects. Each contributor seems t o cover the subject quite adequately and cites extensive references to publications by many other top persons in the fields, thus

This book gives the results of an international survey of some 800 species of plants rich in tannins, the use of which are extended today t o deep-oil well drilling, ink and synthetic materials manufacture, boiler-water treatment, less extensively in plastic manufacture, and in medicine, as well as in the leather industry. The sources of the tannins are divided into barks, woods, fruits, leaves, roots, and plant galls. The plants selected were those known t o be of use by man somewhere in the tanning of leather and those species with 10 per cent or higher tannin content and which may be potential sources of tannin. Botanical origins of the plants and such topics as cultivation, collection, uses, geographical sources, and other pertinent informa-