Aquametry. By John Mitchell Jr., and Donald Milton Smith. Interscience Publishers, Inc., New York, 1948. xi + 444 pp. 15 × 23 cm. Price $8

Aquametry. By John Mitchell Jr., and Donald Milton Smith. Interscience Publishers, Inc., New York, 1948. xi + 444 pp. 15 × 23 cm. Price $8

236 JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION defined as “a sterile solution of Hexobarbitone Sodium in Water for Injection which is free ...

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236

JOURNAL OF THE

AMERICAN PHARMACEUTICAL ASSOCIATION

defined as “a sterile solution of Hexobarbitone Sodium in Water for Injection which is free from carbon dioxide. I t is prepared by dissolving the contents of a sealed container in the required amount of water for Injection immediately before use.” The number of tablets increased from 1 in 1932 to 49 in 1948. In addition to tablets of the Seventh Addendum, 18 new ones were added. Perhaps the most unique feature about the tablet monographs is that in addition to listing “usual sizes,’’ a specific dosage is t o be dispensed if the physician does not specify. For example, under Tabellae Acidi Ascorbici it advises, “If the quantity to be contained in a tablet is not stated, tablets containing, in each, 50 mg. shall be dispensed or supplied.” In addition weight limitations are placed upon individual tablets based on a percentage of the average of the sample. All in all, t6e British have done a commendable job in their Pharmacopceia of 1948 under conditions far more difficult than we have ever experienced. Congratulations from all pharmacists, the world over, are in order. JR., and DONALD Aquametry. B y JOHNMITCHELL MILTONSMITH.Interscience Publishers, Inc., New York, 1948. xi 444 pv. 15 x 23 cm. Price $8. During recent months, analytical chemistry has been struggling in the face of the dramatic discoveries of organic and physical chemisfs t o make the scientific public more conscious of its importance. The series on Chemical Analysis published by the Interscience Publishers has been of material assistance in that regard. Edited by B. L. Clarke and I. M. Kolthoff and with such men as Ashley, Sandell, Willard, and others as a n advisory board, the series on monographs of modern chemical analysis has been welcomed by many. Aquametry is Volume V of the series. The finding of moisture in all sorts of substances has been a very important determination. In many analytical laboratories a drying procedure is probably carried out more frequently than any other test. Oven drying, distillation, and many other techniques have been used for this determination. But it was not until the introduction of the Karl Fischer method in 1935 that a precise chemical method was available. That the Karl Fischer method is of value is evidenced by the voluminous literature recorded on the subject during the fourteen years since its introduction. However, the application of this method is frequently not easy. To evaluate the method critically in book form provides, therefore, a monograph, exceedingIy valuable to analytical and control chemists.

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This book on Aquametry, a name coined by the authors, is divided into two parts. Part 1 deals with the specific quantitative determination of water by the Karl Fischer reagent. The nature of the reagent is discussed as well as the general directions for its use in different methods. General applications of the reagent t o determine not only moisture, but functional groups, are discussed. The last chapter in the section is given over to the determination of water in commercial organic materials. Part 2 deals with organic reactions involving the liberation or consumption of water. Here one finds separate chapters on the determination of alcohols, carboxylic acids, amines, peroxides, etc. A unique and helpful feature of this useful book is a chapter on proposed further studies. Here one finds many desirable projects in both the fundamental and applied fields. The book is well documented and both subject and author indexes appear to be carefully done. The paper, binding, and general workmanship of this book are of the usual high quality found in this series.

The Literature om Strefltomycin, 1944-1948. By SELMAN A. WAKSMANRutgers University Press, New Brunswick, N. J. 1948. xv f 112 pp. 15 x 23 cm. Price $3. Although the isolation of streptomycin was announced in January, 1944,literature has accumulated about 1200 scientific papers during the intervening years. It is fitting, therefore, that the senior discoverer of streptomycin should assemble the references for those interested. This book opens with a reproduction of the first paper announcing streptomycin as it appeared in the Proceedings of the Society for Experimental Biology and Medicine, 55, 66-69, 1944. This is followed by a selective list of general references on the actinomyces, their antagonistic properties, and on streptothricin. Following this, appear 1171 references t o streptomycin arranged in chronological order. An author index and a subject index complete the book. Die Chernische Industrie und ihre Nebenprodukte. Verlag fur wirtschaftsaliteratur G.m.b.H., Burstwiesenstrasse53, Zurich, 3. 1947. 253 pp. 14.5 x 22.5 cm. To those who have occasion t o use information concerning Swiss chemical firms, this directory will be useful. The directory contains a n extensive list of the Swiss chemical and allied industries, arranged according t o products. Names and addresses of each firm, leading executives, dates of esta blishment, banking connections, products and brands, and other essential information are given.