Dysplasie bronchopulmonaire: devenir et traitement des formes sévères

Arch Pddlarr I i 995) 2.628435 0 Else&r. Paris

628

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Dysplmie bronchopuhnonaire:

devenir et traitement des fo. yes s&&es

C Hemabessi&rel, B Monk:‘, C Gaultier*, F Beauflls3, K Benali4, L Cathelineaul*

(Rep Ic 6 juillct 1994; &x+6

Ie 2 janvicr1995)

Le devenir des fotmes s&&es de Qsolasic bronchopubuonaim (DBP) n&es&ant UN assistance mspiratoire. prolongtc par venti!?tion mkanique \W ct/ou oxygdnod&apie (0,) n’est pas &luC et les indicateun pcnnettant d’en guidcr la U&apcutiquc no sent pas d&Xmti. Population m&ho&s. - Now avons .analysC r&rospectivement Its dossiers de 49 nounissoos, 00s cntm 1982 et 1990, atteints de DBP. en Vh4 etlou Oz A 12 mois et plus, dcmt la p&c en chatge tcspitatoii et mtttitionoelle a Ctd pnkise. Trois gtoupea d’eofants ant Cti Minis: gtuupe 1: 26 cnfants en VM depuis la naissancc; ~roupc II: 7 c&ants mrrCs&~VM~lel~moisdevie,puismmisenVMtardivcmnt;groupe~:16 enfants en ventilatiotl spontatk+e(VS) sQus 0s.

et

Ct. CbCZ70% d’CtlttC CUX. Utl XSyOChtOtliStttC thUtaCO-XbdUttlitl~ WCC tCCNtCmClltdCS muscksaWomiaauxpeadsotlpsommil@CO,Olpourtwtcs~).tama~~

de3 ezfantS.60%. pkmtait des broocbospapms @ = 0.02). L’cVolution a Cccfivomble chcx ks49~~aapla~&~~~&l’os~2u4~. C~-ncIUsionr. - Ces rdsultats indiquent qua l’insuffknce respiratuire majeurc du n~~ni~sw d pr6matun?pcmt CrrcSuzmolltce en appliqumt use assistanw res&atoirc et nutritiomeUe pmlUog6c pmlant la phase de d6veloppemmt postnatal du p~umon; UM vakur de la Cl dyn infdtieute B 50% cst predictive du bcsoin d’uo tmitcment par VM

pmkmg~. et le sevmge de la VM IICpcut se faire tam quc pctsistc une augmentation du travail vcntilatoii. ptimatari

I mdadie des membranes

byslincs

I dysphk

bronchopulmonain

I

cvolutku 1 long teran!

Sttmmsry - Outcume atd tnxttnentof severe bmnchopulmonary dyspksk. Background - The outcome of severe forms of bronchopulmonory dysplasia (BPD) leading to a prolonged dependence on mechanical ventilation (MV) an&or oxygen therapy (OJ is not evaluated, andfaclors of guidance to treatment are not established. Population and methods. - The medical records of 49 infants, born between 1982 and 1990, wirh BPD who required MV and or 0, afer 12 months of lift were remxpectively reviewed. Three groups of infants were d&ted: groupe I: 26 infonts on MY sbzce birth:

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