General biochemistry. 2nd ed. By Joseph S. Fruton and Sofia Simmonds. John Wiley & Sons, Inc., New York, 1958.  x + 1077 pp. 15 × 22.5 cm. Price $18

General biochemistry. 2nd ed. By Joseph S. Fruton and Sofia Simmonds. John Wiley & Sons, Inc., New York, 1958.  x + 1077 pp. 15 × 22.5 cm. Price $18

Book Notices The Impact of the Antibi0tic.r on Uedicine and Society. Edited by Iago Galdston. International Universities Press, Inc., New York, 1958. ...

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Book Notices The Impact of the Antibi0tic.r on Uedicine and Society. Edited by Iago Galdston. International Universities Press, Inc., New York, 1958. x 222 pp. 14 X 21.5 cm. Price $5. This monograph, the second published by the Institute of Social and Historical Medicine of the New York Academy of Medicine, covers a wide field starting with “The Microbiology of the Soil and the Antibiotics,” by S. A. Waksman. to “The Effects of the Antibiotics on Society,” by L. B. Hobson. Some of the other topics are: historical surveys of early antibacterial and antibiotic concepts, mass production of antibiotics, application to plant and livestock industry, and the extent of their impact on clinical medicine. No index is included.

A n Introdamion to Pharmacology and Therapeutics. 9th ed. By J. A. Gunn. Oxford University 327 pp. 12 X 18.5 Press, London, 1958. ix cm. Price 64.25. This introductory textbook had not been revised since 1948. The author notes that the medical practitioner finds it hard to keep up with the rapid and continuous advances in therapeutics; that a student faces a list of outlandish names with which he must associate pharmacological and therapeutical properties. As a discriminatory basis he uses the B. P. and U. S. P. for guidance. The most substantial additions in this revision of the text have been made to antibiotics, hormones, autonomic drugs, anesthetics, analgesics, sedatives, and antihistamines. Noting under “Sedatives” that certain drugs are referred t o by the seductive name of “tranquilizers,” the author writes: “Their permanent value in therapeutics is not still precisely established. It can be expected that their indiscriminate use will not be without hazard.”

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Curvent Drug Handbook 1958. By Mary W. Falconer and H. Robert Patterson. W. B. Saunders Company, Philadelphia, 1958. viii 157 pp. 16 X 23.5 cm. This book is a tabulation of about 1,000 drugs in current use, grouped according to pharmacological or therapeutic properties. The information included is given under the column headings: names and general information (includes toxicity and treatment for poisoning), preparations, dosage, administration, and remarks on use. The difficulty in keeping such a listing current is indicated by the fact that N. N. R. 1956 is cited a s a source of material in addition to U. S. P. XV and N. F. X. An index of the drugs listed is appended.

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The Atomic Age and Our Biological Future. By H. V. Br@nsted. Translated by E. M. Huggard. Philosophical Library, A-ew York, 1957. xiv 80 pp. 12 X 18.5 cm. Price $2.75. The aim of this pocket-size book is to describe the biological, and particularly the genetical, effects that might result unless rigorous control of atmospheric radiation is ensured.

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Aliphatic Fluorine Compounds. By A. M. Lovelace, Douglas A. Rausch, and William Postelnek. Reinhold Publishing Corporation, New 370 pp. 15 X 23 cm. Price York, 1958. x $12.50. This book is one of the American Chemical Society monographs. It covers the preparation and properties of all reported organic fluorine compounds other than the aromatic compounds. Each chapter is devoted to a specific class or classes of fluoroorganic compounds such as alkanes, alkenes, alcohols, etc. Physical properties and references are included in the 61 tables of different groups of compounds. References are given a t the end of each chapter, and an index is appended.

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American Drug Index 1958. By Charles 0.Wilson and Tony Everett Jones. J. B. Lippincott Co., Philadelphia, 1958. 716 pp. 14 X 21 cm. Price $5. The third edition (1958) of this very useful compilation of generic, trade, and chemical names and composition of drugs and dosage forms, with indicated uses of pharmaceuticals and chemicdk, continues the comprehensive coverage of this constantly expanding field. The 1958 edition’s 716 pages of condensed information indicates the added material when compared with the 650 pages in 1957 and 576 pages in 1956.

Fat Consumption and Coronary Disease: The Ezdutionary Answer to this Problem. By T. L. Cleave. Philosophical Library, New York, 1958. 40 pp. 12 X 18.5 cm. Price $2.50. The author suggests two main rules in eating: Eat foods in their natural state (permits simple cooking). Eat foods in strict proportion to the appetite (mixtures only in accordance with personal tastes). Our Nuclear Adventure, Its Possibilikies and Perils. By D. G. Arnott. Philosophical Library, Sew Ynrk, 1958. xi 170 pp. 14 X 22 cm. Price $6.00. This small book is a review of basic information pertaining to nuclear reactions and the related behavior of mankind with this new force.

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General Biochemistry. 2nd ed. By Josepli S. Fruton and Sofia Simmonds. John Wiley & Sons, 1077 pp. 15 X 22.5 Inc., New York, 1958. x cm. Price $18. This book presents a revision of the first edition 42, .5@7(1953). which was reviewed in THISJOURNAL, The style and arrangement has been retained, and a new chapter on Alternative pathways of carbohydrate metabolism has been added. It includes many references and a good index is appended. The book is intended as a textbook which presents the structure of modern biochemistry from a general point of view, and it is well done.

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