Leiomyosarcoma in The Buccal Mucosa

Leiomyosarcoma in The Buccal Mucosa

OOOO Volume 117, Number 2 lesion, histopathological diagnosis was squamous cell carcinoma. Treatment was mandibular resection and radiotherapy. Althou...

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OOOO Volume 117, Number 2 lesion, histopathological diagnosis was squamous cell carcinoma. Treatment was mandibular resection and radiotherapy. Although metastasis was not present, treatment was radical, evidence of the need for early diagnosis to obtain a better prognosis.

PE-191 - LEIOMYOSARCOMA IN THE BUCCAL MUCOSA. JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, PRISCILA LIE TOBOUTI, MARILIA TRIERVEILER MARTINS, HAROLDO ARID SOARES, CELSO AUGUSTO LEMOS. FACULDADE DE ODONTOLOGIA DE SANTOSUNIMES/FACULDADE DE ODONTOLOGIA DA USP. Black woman, 39, had an asymptomatic nodule in the left buccal mucosa for 18 months. She reported an asymptomatic, slow-growing lesion, with mild, sporadic paresthesia in the area. A submucosal asymptomatic fibrous nodule 1 cm in diameter and covered by regular mucosa was observed at intraoral examination. The clinical diagnosis was a benign neoplasm of the salivary gland X neural benign neoplasia. Histopathological examination revealed a fragment of a mesenchymal neoplasia formed by a dense proliferation of fusiforms cells with stretched cell nuclei. Cell and nuclei polymorphism was observed, along with numerous atypical mitoses and a coagulated necrotic region. The immunohistochemical reaction was positive to smooth muscle actin, HHF35, and laminine and negative to S-100, CD-34, and desmine. KI-67 level was high (over 20%). The neoplasm presented 10 mitoses/10 sites at 400 magnification. The definitive diagnosis was leiomyosarcoma. The patient was referred to an oncologic hospital for treatment.

PE-192 - LEOPARD SYNDROME IN TWINS: CASE REPORT. IARA RAFAELLA FERREIRA TAVARES, LAURA PRISCILA BARBOZA DE CARVALHO, MARIA CRISTINA HONORATO, LEONARDO ANTUNES TRINDADE, VILSON LACERDA BRASILEIRO JÚNIOR, GLÓRIA MARIA PIMENTA CABRAL, GILKA SOARES SAMPAIO ANDRADE. CENTRO UNIVERSITÁRIO DE JOÃO PESSOA- UNIPÊ. Leopard syndrome (multiple lentigines syndrome) is a dominant autosomal disorder that results in skin and skeletal problems and problems with the cardiovascular system. LEOPARD is an acronym for manifestations of the syndromee lentigines, electrocardiographic abnormalities, ocular hypertelorism, pulmonary stenosis, abnormal genitalia, retarded growth, and deafness. Clinical diagnosis is based on lentigines and two other symptoms or, in cases where lentigines is absent, three other symptoms and at least one of the parents having the disorder in the first degree. Twin white men, 21, had multiple lentigines syndrome. The paternal grandmother has the syndrome and the father had lentiginosis. The patients present multiple lentigines on the skin, ocular hypertolorism, abnormal genitalia, intellectual deficiencies, delayed speech, and visual disabilities. Oral examination found mandibular retrognathia. Because of their various problems, the patients are being treated according to a multidisciplinary approach, including orthodontic treatment.

PE-193 - LICHEN PLANUS ASSOCIATED WITH CHRONIC HEPATITIS C: DIFFICULT DIAGNOSIS AND MANAGEMENT OF A CASE. SORAYA DE MATTOS CAMARGO GROSSMANN, FLÁVIA ROBERTA DOS SANTOS, DIASSIANNE ALVES ESTEVES OTTONI, LUCINEI ROBERTO DE OLIVEIRA, TUFI MEYER, ROSÂNGELA TEIXEIRA. UNIVERSIDADE FEDERAL DE MINAS GERAIS/UNIVERSIDADE VALE DO RIO VERDE.

ABSTRACTS Abstracts e169 Man, 61, came to the Universidade Vale do Rio Verde complaining of “pain in the tongue.” The patient had chronic hepatitis C and also reported difficulty in speaking and feeding and loss of taste sensation. Intraoral examination noted ulceration in almost all tongue areas and extreme symptoms associated with white plaques, which developed over 2 years. The clinical findings and medical history yielded primary diagnostic hypothesis of erosive lichen planus associated with secondary Candida infection. The patient was initially prescribed topical Nystatin; after 7 days an incisional biopsy was performed. Because the symptoms grew worse, dexamethasone was prescribed. The histopathological examination revealed an inflammatory process but did not yield a definitive diagnosis. The patient was prescribed systemic and topical dexamethasone and a new biopsy was performed. He is now being followed in our service. (Support: CNPq; Fapemig).

PE-194 - LICHENOID REACTIONS OF THE ORAL CAVITY: A DIFFICULT DIAGNOSIS, PRESENTATION OF TWO CASES, AMALGAM AND CINNAMON LICHENOID REACTION. MÁRCIA ABDEL MASSIH, VICTOR ÂNGELO MONTALLI, VERA CAVALCANTI DE ARAÚJO, FABRÍCIO PASSADOR-SANTOS, PAULO DE CAMARGO MORAES. FACULDADE DE ODONTOLOGIA SÃO LEOPOLDO MANDIC. Lichenoid reaction is a common entity among skin pathologies but a relatively rare condition in the oral mucosa. Amalgam restorations, foods, mouthwashes, toothpastes, synthetic resin, and topical treatments can act as triggering factors in oral mucosal cases. However, the clinical diagnosis remains a challenge because of the clinical similarity between lichenoid reactions and oral lichen planus. Two cases of lichenoid lesions will be presented: the first one was an allergic reaction caused by the components of amalgam restorations and the second one a reaction to chronic cinnamon contact. Both were localized in the buccal mucosa. Lichenoid reactions are alterations in the mucosal tissue resulting from hypersensitivity to some chemical components, whereas lichen planus shows patterns such as white striations, erythema, erosions, white papules, or plaques. Besides presenting two cases, this report discusses the diagnosis and clinical findings of these contact allergy reactions.

PE-195 - LOCAL RECURRENCE OF SQUAMOUS CELL CARCINOMA AND IMPORTANCE OF FOLLOW-UP: REPORT OF FOUR CASES. MATHEUS HENRIQUE ALVES DE LIMA, AMANDA LAÍSA DE OLIVEIRA LIMA, CAMILA DE QUEIROZ TORRES BARROS, EVELLYNE DE PEREIRA CAVALCANTE, MATEUS BARROS CAVALCANTE, CAMILA MARIA BEDER RIBEIRO, SONIA MARIA SOARES FERREIRA. CENTRO UNIVERSITÁRIO CESMAC. Squamous cell carcinoma (SCC) has low recurrence after treatment and the elimination of deleterious habits. Four cases of SCC are reported in which the patient developed local recurrence after treatment. Man, 68, who had radiotherapy in 2008 demonstrated a reddish lesion on the soft palate. Histological examination showed “carcinoma in situ” (2011). Woman, 66, who had radiotherapy in 2007, presented a whitish verrucous lesion on the left side of the hard palate. Histological characteristics were compatible with “carcinoma in situ” (2013). Woman, 53, underwent radiotherapy and chemotherapy in 2005, then presented an ulcerated lesion on the tongue. Oral biopsy was diagnostic for speckled leukoplakia with severe dysplasia (2011). Man, 71, had radiotherapy in 2009, then developed an ulcerated lesion on the