Microbiology. 2nd ed. By Florene C. Kelly and K. Eilene Hite. Appleton‐Century‐Crofts, Inc., New York, 1955. xi + 615 pp. 17 × 23.5 cm. Price $7.50

Microbiology. 2nd ed. By Florene C. Kelly and K. Eilene Hite. Appleton‐Century‐Crofts, Inc., New York, 1955. xi + 615 pp. 17 × 23.5 cm. Price $7.50

582 JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION The Biologic Efects of Tobacco. ERNESTL. WYNDER. Editor. Little, Brown and Company, Boston, ...

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582

JOURNAL OF THE

AMERICAN PHARMACEUTICAL ASSOCIATION

The Biologic Efects of Tobacco. ERNESTL. WYNDER. Editor. Little, Brown and Company, Boston, 1955. xiii f 215 pp. 14.5 x 21 cm. Price $4.50. The effect of tobacco on human health has been a controversial issue for many years. During the past several years contradictory reports have appeared in the literature concerning the relationship of the use of tobacco to certain diseases, with particular emphasis upon the incidence of lung cancer in cigarette smokers, as compared with nonsmokers. The Biologic Efects of Tobacco is designed to present the facts about the possible relationship of tobacco and tobacco smoke to human health. I t summarizes more or less objectively the evidelice and documents it by references t o the original literature on the subjects covered. Tobacco consumption has been most frequently linked to diseases of the cardiovascular system, the gastrointestinal tract, allergies, and certain types of cancers. The data assembled are presented in seven well-written chapters. In the first chapter the cheinistry of tobacco is reviewed, and of special interest here is a list of compounds which have been reported as present in tobacco smoke. I n the second chapter on pharmacology, compounds of pharmacologic interest in tobacco smoke, with special emphasis upon the properties of nicotine, are discussed. Other chapters which follow cover the physiologic effects, pharmacologic considerations, and clinical data on the effects of tobacco on the cardiovascular system, the gastrointestinal tract, and allergies. In one chapter entitled “Neoplastic Diseases,” Dr. Ernest L. Wynder, Head, Section of Epidemiology, and Associate, Sloan-Kettering Institute for Cancer Research, summarizes previously published clinical and statistical reports dealing with the role of cigarette smoking in the causation of lung cancer and cancer of the larynx, tongue, buccal mucosa, floor of the mouth, gums, and esophagus. From a study of these data, he concludes that cigarette smoking is a causative factor in lung cancer, and increases significantly the risk of cancer development in the buccal cavity. The seventh and final chapter entitled “Cause and Effect,” by E. Cuyler Hammond, Director of Statistical Research of the American Cancer Society, summarizes the evidence, based upon epidemiologic research, which strongly indicates a definite relationship between cigarette smoking and the incidence of certain neoplastic diseases. The book is provided with an adequate subject index and with an author index which adds greatly t o its value as a reference to the several ramifications of the subjects discussed.

Electrochemistry i n Biology and Medicine. THEODORE SHEDLOVSKY, Editor. John Wiley & Sons, IPC.,New York; Chapman & Hall, Ltd., London, 1955. xii 369 pp. 16.5 x 23.7 cm. Price $10.50.

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This book is based upon the papers presented at a symposium on electrochemistry in biology and medicine sponsored by the Electrochemical Society in April, 1953. The subjects covered include membranes, nerve and plant cells, biologically important ions, and applications of polarography, electrocardiography, and electroencephalography in medicine.

Vol. XLIV, No. 9

Experimental data, tabulations, diagrams, and pictures increase the value of the text; and the references and general index make it an excellent addition to the medical and pharmacological research libraries.

The Hypophyseal Growth Hormone, Nature and Actions. RICHMOND W. SMITH, OLIVER H. GAEBLER,and C. N. H. LONG,Editors. The Blakiston Division, McGraw-Hill Book Company, Inc., New York, 1955. xv 576 pp. 16.5 x 23.5 cm. Price $12.

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This is a record of the complete proceedings of an international symposium held in October, 1954. The book was prepared for publication with the view that the recorded data, methods, and speculations pertaining to the research development on the hypophyseal growth hormone could be made available quickly in this accelerating field of study. Growth hormone has as yet shown little clinical promise but much is being learned of its functions in the basic biological and medical sciences. The printing, format, and illustrations in the book are excellent; but the absence of a general index is a regrettable omission in a compilation that is a splendid review and reference volume in its field.

Microbiology. 2nd ed. By FLORENE C. KELLY and K. EILENE HITE. Appleton-Century-Crofts, Inc., New York, 1955. xi 615 pp. 17 x 23.5 cm. Price $7.50.

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The first edition of this book was published in 1949 and was reviewed in THISJOURNAL, 39, 59 (1950). The advances in microbiology since 1949 include increased knowledge of bacterial genetics, cellular structure, biochemistry, metabolism, immunology, bacterial viruses, as well as new disease agents and antibiotics. The authors have incorporated much of this information in the second edition without going into great detail. An additional section on staining methods and formulas for stains, indicators, culture media, and tests for biochemical activities is appended. A chronological list of discoverers and their contributions starting with Roger Bacon (1267) and ending with Albert Calmette (1924) is given. The book is a suitable text on introductory microbiology for pharmacy students and general science courses.

Biochemistry. An Introductory Textbook. By FELIX HAUROWITZ.John Wiley & Sons, Inc., New York, 1955. 16 485 pp. 15.5 x 23.5 cm. Price $6.75.

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Dr. Haurowitz’s book can be recommended as an excellent and original introduction into the field of general biochemistry. Emphasis is placed on intermediary metabolism and on the mechanism of metabolic reactions, and recognition is given t o the fact that the truly significant problems of biochemistry are those of living cells and tissues. The voluminous material which resulted from research in the field of proteins, particularly during the last twenty years, has been carefully selected and treated in such a way that its study is considerably facilitated. It deserves mention that the author stresses the act that there is no need for the student to memorize