Book Notices Naturally Occurring Quinones. By R. H. Thompson. Academic Press Inc., New York, and Butterworths Scientific Publications, London, 1957. vii 302 pp. 14 x 21.5 cm. Price $9. A comprehensive account of the quinone pigments is presented. The quinones are considered mainly from a chemical standpoint with emphasis on their reactions and constitution. The literature is covered to the end of 1956 and some references to papers published in 1957 are included. This book should be of particular interest to those concerned with natural or synthetic coloring materials.
British Pharmacopoeia 1958. Published under the direction of the General Medical Council. The Pharmaceutical Press, 17 Bloomsbury Square, London, W. C. 1, 1958. xxvi 1012 pp. 15 x 22.5 cm. Price 3€, 3 s. plus postage. Distributed by The Rittenhouse Bookstore, 1706 Rittenhouse Sq., Philadelphia 3, Pa. The British Pharmacopoeia 1958 is the ninth edition since the amalgamation of the London, Edinburgh, and Dublin pharmacopoeias in 1864. Since the 1953 edition, 160 new monographs, which include 60 new chemicals and 100 preparations of these substances, have been added. Among the 138 items not carried over from B.P. 1953 are aromatic spirit of ammonia, belladonna root, chenopodium oil, quassia. nutmeg, and the class of preparations named lamellae. The antibiotic drugs have been increased by admission of 18 basic substances and their preparations; the corticosteroids have 12 new monographs, including prednisone and prednisolone; and radioisotopes of iodine and phosphorus are included. The newer anthelmintic piperazine derivatives are in and the old chenopodium oil is out. An odorless U.S.P. or N.F. drug might not be odorless by the new B.P. test which states: “Examine a sample of not more than 25 g. immediately after opening the package. If any odour is discernible, transfer the sample rapidly to an open container and re-examine after one minute. If the odour is still discernible, the sample does not comply with the description ‘odourless.’ ” Under “Indicators” (page 5), the operator is permitted to substitute indicators for one another providing they are in the same range of color change. “but where any doubt exists as to the equivalence of indicators for a particular purpose, the indicator specified in the text must be used.” The Introduction includes a list which shows major differences in titles of monographs in B.P. 1958 and the International Pharmacopoeia, 1st ed., vols. I and 11. There are 27 appendixes. Appendix X X I is divided into 3 parts: A, disintegration test for tablets; B, modification of A for enteric-coated tablets ; C, required diameters of uncoated forms are listed for official tablets, with the provision that “(a)where the diameter is
given as ten thirty-seconds of an inch or more, the stated diameter may be exceeded by not more than one thirty-second of an inch. (b) a deviation of f 5 per cent is allowed.” Permission is given in 11 out of the 120 monographs on tablets for the addition of a suitable coloring agent t o the coating “because unfortunately uncolored coated tablets have not been made available. Similar provision has been made for some capsules.” Where colored and uncolored coated tablets are available the colored tablet is not recognized as the B.P. article. The B.P. 1958 is a technically excellent book of standards. The members of the British Pharmacopoeia Commission are to be commended on the performance of their duties in compiling this revision.
The Diagnosis and Trea.tment of Infection. By D. Geraint James. Charles C Thomas, Springfield, Ill., 1957. 14 x 22.5 cm. viii 234 pp. Price $6. This book aims to correlate diagnosis (aided by clinical laboratory findings) with treatment of infections (particularly with specific chemotherapeutic agents) for the student and practitioner of medicine. The text is divided into three main sections: Chemotherapeutic agents, Microorganisms causing human disease, and Infections of systems (respiratory, heart, etc.). Much useful information is compiled in 24 tabulations. A subject index is appended.
Pesticide Handbook. 9th ed. By D. E. H. Frear. College Science Publishers, State College, Pa., 1957. 216 pp. 15.5 x 23 cm. Paper bound $1.50; cloth bound $8. A unique compilation of proprietary names of apparently all the pesticides used in this country, with the composition, manufacturer’s name, and special applications. Besides other useful information, there is a classification of products by use of application (adjuvants, animal repellents, diluents, fungicides, etc.). This is an indispensable manual in the field of pest control. Encyclopedia of Chemicul Technology. 1st Supplement Vol. Edited by Raymond E. Kirk and Donald F. Othmer. Interscience Publishers, Inc., New York, 1957. xviii 974 pp. 19.5 x 27 cm. This first supplement volume of a useful compilation of documented information includes 51 articles ranging from (A) Acrolein, through ( P ) Psychopharmacological agents, t o (W) Water demineralization. A 45-page subject index for this volume is appended. The composite index for the 15 numbered volumes of the Encyclopedia is included in vol. 15 which was reviewed in THIS JOURNAL, 46, 390( 1957).