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P340 Quality of life of breast cancer patients undergoing radiotherapy
Friday, 18 March 2011
Poster Session II. Supportive care/Psychology
S83
regarded as being in the normal range, a score of 11 or higher indicating probable presence (’caseness’) of the mood disorder and a score of 8 to 10 being just suggestive of the presence of the respective state. Results: 49 patients (58.3%) were found to be responders to the NACT, while 35 (41.7%) of patients did not respond to chemotherapy. The correlation of depression and response to NACT was found to be statistically significant (chi-square test, p value <0.05).An interesting observation in this study, was that 24 (57.1%) of patients from nuclear families showed significant levels of depression, in contrast to the 11 (36.2%) patients of joint families (p < 0.05). Conclusion: It was apparent that the anxiety and depression in breast cancer patients are both on account of the disease and its treatment. The response to NACT cycles was found to have a direct correlation with depression, the distress levels being lower in responders. Statistically this was found to be the most important variable determining the psychological status of the patients. Disclosure of Interest: None Declared
Most of these women were economically dependent on their husbands. Among these patients 5 had a family history of breast carcinoma. All of these patients had undergone surgery. Seventeen patients had had breast conserving surgery, while 46 patients had undergone radical surgery. All but 7 patients in the study group had received chemotherapy and radiotherapy after surgery. The various physical symptoms noticed after surgery were hot flushes, pain, fatigue restricted shoulder movements and sleep disturbances. While most of the women (38/63) had problems associated with body image and social activities, but the problems associated with sexual functioning was reported by much less (16/63). Conclusion: Detailed analysis will be presented in conference. The psycho-social issues after breast cancer and its treatment are important to be studied and addressed in developing countries. Disclosure of Interest: None Declared
P340
Quality of life of breast cancer patients undergoing radiotherapy
M.I. Kaadan1 . 1 Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic
G. Bulotiene1 , V. Ostapenko2 , L. Zalnierunaite3 . 1 Department of Physical Medicine and Rehabilitation, 2 Department of Breast Surgery and Oncology, Institute of Oncology, Vilnius University, 3 Institute of Public Health, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Goals: Breast cancer has traditionally been surrounded by stigma worldwide. This stigma is expressed in a variety of ways, including: ostracism, rejection, discrimination. The aim of this paper is to present details of stigma development in some societies, and a proposal of how could we release an enlightening campaign aiming to erase or fight stigma associated with breast cancer. Methods: The paper provides an analysis of the processes by which stigma has emerged and become associated with breast cancer. It also explores the process by which these associations could be loosened, identifying distinctive features of stigma that may guide intervention programs; and evaluating changes in the magnitude and character of stigma in response to interventions and social changes. This will facilitate our campaign aiming to erase or fight stigma associated with breast cancer. We have to recognize that in Muslim communities specifically, any anti stigma campaign to be succeeded should be based on some Islamic concepts, which related to the issue. Results: Stigma towards people with breast cancer in some countries have a detrimental effect on their ability to obtain services, their recovery, the type of treatment and support they receive, and their acceptance in the community. Conclusion: Although, research on breast cancer stigma has grown dramatically over the past two decades in the west, I hope that this paper may provoke more anti breast cancer stigma initiatives and deeds in North Africa and the Middle East. Disclosure of Interest: None Declared
Goals: The aim of the study was to compare quality of life and emotional status of women after mastectomy and breast conserving treatment undergoing radiotherapy. Methods: We evaluated 126 patients with cT1-T2/N0-N1/M0 stages of breast cancer undergoing outpatient radiotherapy at the Institute of Oncology, Vilnius University between June 2009 and March 2010. The study participants filled in the EORTC QLQ-C30, EORTC QLQ-BR23 quality of life questionnaires, the Hospital Anxiety and Depression Scale and a form about their social status. Quality of life and levels of anxiety and depression after mastectomy or breast conserving treatment (BCT) were compared. Results: The mean age of the patients was 54.0±11.8 years. Females after mastectomy had better emotional, social, sexual functioning and better overall quality of life. Females after BCT had better physical functioning and showed better results in symptom scales. They were less stressed by body image and future perspective changes. Anxiety and depression were found respectively in 19.8% and 22.2% of patients from the mastectomy group and in 21.4% and 13.6% from BCT group. Conclusion: After BCT physical functioning and body image was better. Social, emotional, sexual functioning and the overall quality of life were better after mastectomy. Prevalence of anxiety and depression was high in both groups (mastectomy and BCT). Our findings suggest that women with early breast cancer need a psychosocial support during radiotherapy. Disclosure of Interest: None Declared
P341
Psychosocial impacts of breast cancer and its treatment on Indian patients
S. Chander1 , S. Bhasker1 . 1 Radiotherapy Department, AIIMS, New Delhi, India, All India Institute of Medical Sciences, New Delhi, Delhi, India Goals: The study of psychosocial impacts of breast cancer and its treatment in the context of Indian circumstances is important in view of the relatively sparse availability of resources to provide psychological, social and emotional support to these patients. The purpose of the this presentation is to report the results of a descriptive study that evaluated the psychological, emotional, physical, sexual effects of breast cancer and its treatment on these women. Methods: A semi-structured interview of 63 women, either undergoing or completed treatment for carcinoma breast, was undertaken. A questionnaire was developed locally to provide a basis for interviewing these patients. Parameters of study concerned the personal, social, economic, physical symptoms, psychological, sexual, body image perception and spiritual aspects. Results: The patients were in the age range of 25−68 years. Twenty nine women were premenopausal. And 47 out of the 63 women were housewives. All but 8 women were Hindus by religion. All these women were married. They were living in nuclear families in and around Delhi (49/63).
P342
P343
Stigma attached to breast cancer in North Africa and the Middle East, how to erase it?
CARIATIDE trial: the impact of educational materials (EM) on patients’ compliance with adjuvant aromatase inhibitor (AI) therapy and quality of life (QoL)
C. Markopoulos1 , P. Neven2 , M. Tanner3 , M. Marty4 , R. Kreienberg5 , L. Atkins6 , A. Franquet7 , V. Deschamp8 , presented on behalf of the CARIATIDE investigators. 1 Athens University Medical School, Athens, Greece, 2 UZ Leuven, Leuven, Belgium, 3 Tampere University Hospital, ˆ ¨ St Louis, Paris, France, 5 UniversitatsTampere, Finland, 4 Hopital Frauenklinik, Ulm, Germany, 6 King’s College, London, United Kingdom, 7 IDDI, Louvain-la-Neuve, 8 AstraZeneca, Brussels, Belgium Goals: Long-term compliance with adjuvant AI is problematic, and depends on many factors that are not well defined. Provision of EM may improve patients’ treatment compliance and affect patients’ QoL. Methods: CARIATIDE is a 2-year global observational study (NCT00681122) conducted to determine whether EM could influence patients’ motivation, and improve compliance with adjuvant AI treatment. Patients were randomised 1:1 to Group A: Standard Therapy or Group B: Standard Therapy + EM, consisting of a range of information on breast cancer related topics. The primary endpoint was compliance rate for the adjuvant AI medication, defined as the proportion of subjects taking at least 80% of their adjuvant AI medication; switching to tamoxifen resulted in a non-compliance score. Patients’ satisfaction with care was assessed using the EORTC IN-PATSAT32 questionnaire; a modified version was developed to assess investigator-perceived levels of care. Mental wellbeing and hormonal medication tolerability were evaluated by GHQ-12 and
Poster Session II. Supportive care/Psychology
S83
regarded as being in the normal range, a score of 11 or higher indicating probable presence (’caseness’) of the mood disorder and a score of 8 to 10 being just suggestive of the presence of the respective state. Results: 49 patients (58.3%) were found to be responders to the NACT, while 35 (41.7%) of patients did not respond to chemotherapy. The correlation of depression and response to NACT was found to be statistically significant (chi-square test, p value <0.05).An interesting observation in this study, was that 24 (57.1%) of patients from nuclear families showed significant levels of depression, in contrast to the 11 (36.2%) patients of joint families (p < 0.05). Conclusion: It was apparent that the anxiety and depression in breast cancer patients are both on account of the disease and its treatment. The response to NACT cycles was found to have a direct correlation with depression, the distress levels being lower in responders. Statistically this was found to be the most important variable determining the psychological status of the patients. Disclosure of Interest: None Declared
Most of these women were economically dependent on their husbands. Among these patients 5 had a family history of breast carcinoma. All of these patients had undergone surgery. Seventeen patients had had breast conserving surgery, while 46 patients had undergone radical surgery. All but 7 patients in the study group had received chemotherapy and radiotherapy after surgery. The various physical symptoms noticed after surgery were hot flushes, pain, fatigue restricted shoulder movements and sleep disturbances. While most of the women (38/63) had problems associated with body image and social activities, but the problems associated with sexual functioning was reported by much less (16/63). Conclusion: Detailed analysis will be presented in conference. The psycho-social issues after breast cancer and its treatment are important to be studied and addressed in developing countries. Disclosure of Interest: None Declared
P340
Quality of life of breast cancer patients undergoing radiotherapy
M.I. Kaadan1 . 1 Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic
G. Bulotiene1 , V. Ostapenko2 , L. Zalnierunaite3 . 1 Department of Physical Medicine and Rehabilitation, 2 Department of Breast Surgery and Oncology, Institute of Oncology, Vilnius University, 3 Institute of Public Health, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Goals: Breast cancer has traditionally been surrounded by stigma worldwide. This stigma is expressed in a variety of ways, including: ostracism, rejection, discrimination. The aim of this paper is to present details of stigma development in some societies, and a proposal of how could we release an enlightening campaign aiming to erase or fight stigma associated with breast cancer. Methods: The paper provides an analysis of the processes by which stigma has emerged and become associated with breast cancer. It also explores the process by which these associations could be loosened, identifying distinctive features of stigma that may guide intervention programs; and evaluating changes in the magnitude and character of stigma in response to interventions and social changes. This will facilitate our campaign aiming to erase or fight stigma associated with breast cancer. We have to recognize that in Muslim communities specifically, any anti stigma campaign to be succeeded should be based on some Islamic concepts, which related to the issue. Results: Stigma towards people with breast cancer in some countries have a detrimental effect on their ability to obtain services, their recovery, the type of treatment and support they receive, and their acceptance in the community. Conclusion: Although, research on breast cancer stigma has grown dramatically over the past two decades in the west, I hope that this paper may provoke more anti breast cancer stigma initiatives and deeds in North Africa and the Middle East. Disclosure of Interest: None Declared
Goals: The aim of the study was to compare quality of life and emotional status of women after mastectomy and breast conserving treatment undergoing radiotherapy. Methods: We evaluated 126 patients with cT1-T2/N0-N1/M0 stages of breast cancer undergoing outpatient radiotherapy at the Institute of Oncology, Vilnius University between June 2009 and March 2010. The study participants filled in the EORTC QLQ-C30, EORTC QLQ-BR23 quality of life questionnaires, the Hospital Anxiety and Depression Scale and a form about their social status. Quality of life and levels of anxiety and depression after mastectomy or breast conserving treatment (BCT) were compared. Results: The mean age of the patients was 54.0±11.8 years. Females after mastectomy had better emotional, social, sexual functioning and better overall quality of life. Females after BCT had better physical functioning and showed better results in symptom scales. They were less stressed by body image and future perspective changes. Anxiety and depression were found respectively in 19.8% and 22.2% of patients from the mastectomy group and in 21.4% and 13.6% from BCT group. Conclusion: After BCT physical functioning and body image was better. Social, emotional, sexual functioning and the overall quality of life were better after mastectomy. Prevalence of anxiety and depression was high in both groups (mastectomy and BCT). Our findings suggest that women with early breast cancer need a psychosocial support during radiotherapy. Disclosure of Interest: None Declared
P341
Psychosocial impacts of breast cancer and its treatment on Indian patients
S. Chander1 , S. Bhasker1 . 1 Radiotherapy Department, AIIMS, New Delhi, India, All India Institute of Medical Sciences, New Delhi, Delhi, India Goals: The study of psychosocial impacts of breast cancer and its treatment in the context of Indian circumstances is important in view of the relatively sparse availability of resources to provide psychological, social and emotional support to these patients. The purpose of the this presentation is to report the results of a descriptive study that evaluated the psychological, emotional, physical, sexual effects of breast cancer and its treatment on these women. Methods: A semi-structured interview of 63 women, either undergoing or completed treatment for carcinoma breast, was undertaken. A questionnaire was developed locally to provide a basis for interviewing these patients. Parameters of study concerned the personal, social, economic, physical symptoms, psychological, sexual, body image perception and spiritual aspects. Results: The patients were in the age range of 25−68 years. Twenty nine women were premenopausal. And 47 out of the 63 women were housewives. All but 8 women were Hindus by religion. All these women were married. They were living in nuclear families in and around Delhi (49/63).
P342
P343
Stigma attached to breast cancer in North Africa and the Middle East, how to erase it?
CARIATIDE trial: the impact of educational materials (EM) on patients’ compliance with adjuvant aromatase inhibitor (AI) therapy and quality of life (QoL)
C. Markopoulos1 , P. Neven2 , M. Tanner3 , M. Marty4 , R. Kreienberg5 , L. Atkins6 , A. Franquet7 , V. Deschamp8 , presented on behalf of the CARIATIDE investigators. 1 Athens University Medical School, Athens, Greece, 2 UZ Leuven, Leuven, Belgium, 3 Tampere University Hospital, ˆ ¨ St Louis, Paris, France, 5 UniversitatsTampere, Finland, 4 Hopital Frauenklinik, Ulm, Germany, 6 King’s College, London, United Kingdom, 7 IDDI, Louvain-la-Neuve, 8 AstraZeneca, Brussels, Belgium Goals: Long-term compliance with adjuvant AI is problematic, and depends on many factors that are not well defined. Provision of EM may improve patients’ treatment compliance and affect patients’ QoL. Methods: CARIATIDE is a 2-year global observational study (NCT00681122) conducted to determine whether EM could influence patients’ motivation, and improve compliance with adjuvant AI treatment. Patients were randomised 1:1 to Group A: Standard Therapy or Group B: Standard Therapy + EM, consisting of a range of information on breast cancer related topics. The primary endpoint was compliance rate for the adjuvant AI medication, defined as the proportion of subjects taking at least 80% of their adjuvant AI medication; switching to tamoxifen resulted in a non-compliance score. Patients’ satisfaction with care was assessed using the EORTC IN-PATSAT32 questionnaire; a modified version was developed to assess investigator-perceived levels of care. Mental wellbeing and hormonal medication tolerability were evaluated by GHQ-12 and