Pharmaceutical distillation units

Pharmaceutical distillation units

DUCTNEWS Pharmaceutical distillationunits Vaponics offers a line of distillation units for the pharmaceutical industry, including high-velocity single...

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DUCTNEWS Pharmaceutical distillationunits Vaponics offers a line of distillation units for the pharmaceutical industry, including high-velocity singleand multiple effect steam stills and pure steam generators. The systems feature an evaporator design in which water vaporises on the outside of the evaporator tubes; the evaporator coil itself is designed to self-clean. As

the coil expands and contracts during normal operation, any scale formation drops to the bottom of the evaporator, where it is drained to waste without interfering with the production of pure steam. Evaporators that vaporlse inside the tube tend to be plugged with immovable scale. Multiple effect and pure steam generator vessels are

ASME-code stamped, and are built in accordance with FDA/GMP standards to produce pure water meeting current USP specifications for ‘Water for Injection’. Vaponics is one of the few manufacturers to offer titanium on the evaporator and condenser coils of the stills; titanium is far superior to 316 stainless-steel for both corrosion resistance and

improved purity. Vaponics manufactures a complete line of pre-treatment equipment for stills, which includes dual media filters, cartridge filters, and reverse-osmosis, ultrafiltration and deionisation systerns. Vaponics Inc, 20 Reservoir Park Drive, Rockland, MA 02370, USA. Tel: + 1 617 982 9900, fa: + 1 617 982 7108.

Delkoroffers clarifierrefurbishment Filtration system specialist Delkor has introduced a high-rate thickener/clarifier mechanism that allows dated process clarifiers to be uprated to meet current environmental requirements to lower effluent consent limits. The retrofitting packages, based on the company’s internationally known HiRate Thickener/Clarifier equipment, is designed to reduce costly civils, substantially increase throughput (by up to 100%) through the use of well proven

technology, and greatly improve clarification performance to meet lowering consent limits. Of advanced design, the mechanism operates as a clarifier and thickener within a single tank, using a feed injection system which creates a fluidised sludge bed. The sludge bed enhances flocculation effects and promotes particle interaction, which provides an improved capacity of two to three times that of traditional sedimentation-only clarifiers.

SuperiorPTFEmaterialleads to line of new products Innovative product design combined with development of an advanced PTFE material, has led to the introduction by Mace of its Q-Series line of Teflon liquid and gas flow control products. The line is manufactured Tom Hy’PI’FE, a new material developed by Mace, and which is claimed to be greatly superior to standard Teflon PTFE and PFA. HyQPI’FE is 100% virgin FTFE, process-engineered to meet the performance requirements of present and future ultrapure liquid and gas manufacturing operations. This material provides particle-free performance and has increased structural and thermal integrity, which is achieved through precision control of all the process 302

parameters, including Class 100 clean-room material handling and computer-controlled fabric&ion steps. The new Q-Series line has been engineered to utilise the enhanced characteristics of HyQPTFE. The products feature no exposed metal (external surfaces are 100% Hy’PTFE), and their shapes make them clean-room-friendly. In addition, HyQPTFE has an equivalent surface finish to PFA, but it does not suffer from the inherent nonuniformity found in melt-processed polymers, nor does it use Class 1 ozone-depleting chemicals in its base resin fabrication, as does PFA. Mace Products, 2022 West 1 lth Street, Upland, CA 91786, USA. Tel: f 1 714 981 2770, fm: + 1 714 981 8071.

In the currently weak economic climate, refurbishment and uprating programmes during routine shutdowns are becoming a favoured option, because of budget restraints and the major disruption and high cost that a build-from-new

project can involve. With pre-planning, Delko’s retrofit system can be delivered to site and installed in a very short time. Delkor Ltd, Winteyfield Road, Paulton, Bristol BS18 5RF, UK. Tel: + 44 (0) 761 417079.

Crossflowsamplersfor fermentation monitoring A new series of crossflow samplers from A/G Technology provides a simple, costeffective method for obtaining continuous, clean samples for on-line analysis of the fermentation process. Xampler membrane cartridges facilitate real-time fermentation monitoring with greatly reduced disruption to the fermentation process. The disposable cartridges offer an ease and simplicity of operation impossible to achieve with centrifugation or expensive electronic sensing methods. Complex fermentations demand continuous monitoring for optimum results and on-line analytical instrumentation, which can provide rapid assays, and performs best when cells and cell debris have been removed from the sample prior to analysis. Xampler cartridges are hollow-fibre devices engineered with lumen-side and shell-side hold-up volumes of only 1 ml each. These low hold-up volumes, combined with permeation rates of up

to several ml/min, ensure fast flush of the shell-side sample and rapid response of downstream assays. The cartridges are offered in three pore sizes: 0.45 pm and 0.1 pm microfilters, as well as 30,000 NMWC ultrafilters to handle a variety of cell lines and analytical objectives. They are available for sterility. Like all A/G Technology hollow-fibre products, Xampler cartridges are based on proprietary expertise in fabricating the membranes with an imperfection-free morphology. This method renders the ultrafiltration membranes free from macrovoids and the pinhole defects associated with the characteristic structure of conventional flat-sheet membranes and other hollow fibres. They are true, bubble-point-testable membranes. A/G Technology Corporation, 101 Hamwton Avenue. Needham, MA 02194-2628, l&X. Tel: 1 800 248 2535 (tol@i-ee in the US and Canada) or + 1 617 449 5774, fm: + 1 617 449 5786. June 1993

Filtration & Separation