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Public policy and epidemiology
HEPATOLOGYVol. 22, No. 4, Pt. 2, 1995
AASLD PROGRAM
105A
Tuesday Posters #1101 Effect of i s c h e m i a / r e p e r f u s i o n on
h e a t - s h o c k p r o t e i n 70 a n d 90 g e n e e x p r e s s i o n in rat liver: r e l a t i o n to n u t r i t i o n a l status. A Gasbarrini, S Degli Esposti, S De Notariis, P Caraceni, S Loffredo, A Abraham, M Simoncini, A Colantoni, F Trevisani, G Gasbarrini and M Bernardi. Univ. di Bologna and Univ. Cattolica, Roma, Italy; Brown Univ., Providence, RI.
#1102 L y s o s o m a l e n z y m e s as early a n d q u a n t i t a t i v e m a r k e r s of h e p a t i c i s c h e m i a / r e p e r f u s i o n injury. W Liu, O SchSb, J Pugmire, D Jackson, KA Zucker, DE Fry and RH Glew. Dept. of Surg. and Biochem., Univ. of New Mexico, Albuquerque, NM. #1103 Effects of h e p a t o c y t e g r o w t h factor
on d i m e t h y l n i t r o s o a m i n e - i n d u c e d liver i n j u r y in rats. K Okabe, H Suzuki, S Suemori, T Yamamoto, Y Mamata, N Matsumoto, H Mizuno, M Kono, M Suga, M Suzuki, Y Kato, A Sato and T Meguro. Dept. of Internal Med. and Research Lab., Yokohama City Seibu Hosp., St. Marlanna Univ. Sch. of Med., Yokohama, Japan. #1104 I n t e r a c t i o n s of c y c l o s p o r i n e A
a n d its d e r i v a t i v e IMM-125 w i t h rat h e p a t o c y t e s . A Wolf, C Trendelenburg, L Aicher, U Schramm, A Fahr and G Fricker. Sandoz Pharma AG, Basel, Switzerland.
#1105 I n c r e a s e s in i n t r a c e l l u l a r c a l c i u m in n e u t r o p h i l s (PMNs) d u e to formylmethionine-leucine-phenylalanine a n d e n d o t o x i n are b l o c k e d completely b y glycine. RF Stachlewitz, K Ikejima and RG Thurman. Lab. of Hepatobiol. and Toxicol., Dept. of Pharmacol., Univ. of North Carolina, Chapel Hill, NC. #1106 I n d u c t i o n of t h e p e r m e a b i l i t y tran-
s i t i o n b y a g e n t s i m p l i c a t e d in Reye's s y n d r o m e a n d Reye's-like d r u g toxicity: a p o s s i b l e p a t h o g e n e s i s of mitochondrial dysfunction. LC Trost and JJ Lemasters. Dept. Cell Biol. & Anatomy and Curriculum in Toxicol., Univ. of North Carolina, Chapel Hill, NC.
#1107 S e r u m isocitrate d e h y d r o g e n a s e as a m a r k e r of c e n t r i l o b u l a r h e p a t i c n e c r o s i s in t h e e x p e r i m e n t a l m o d e l of rats. Y-H Chung, JA Kim, GS Ahn, IH Song, MS Koh, YS Lee and DJ Suh. Dept. of Internal Med. and Inst. of Life Science, Asan Med. Ctr., College of Med., Univ. of Ulsan, Seoul, Korea.
#1108 T r a n s v e n o u s liver biopsy in f u l m i n a n t , s u b f u l m i n a n t and severe acute hepatic failure. J Gournay, F Durand, C Degott, J Bernuau, S Erlinger and D Lebrec. Serv. d'Hepatol., INSERM U24 and Serv. d'Anatomie Pathol., Hop. Beaujon, Clichy, France.
PUBLIC POLICY AND EPIDEMIOLOGY
#1109 Temporal and geographical variations in the prevalence of p r i m a r y b i l i a r y cirrhosis in Northeast England. JV Metcalf, RS Bhopal, LRMD Scott, J Gray, D Howel and OFW James. Depts. of Med. and Epidemiol., Univ. of Newcastle, Newcastle-upon-Tyne, England. #1110 I m p r o v e d o u t c o m e from s e v e r e
acetaminophen-induced hepatotoxicity. AJ Makin, J Wendon and R Williams. Inst. of Liver Studies, King's College Sch. of Med. & Dentistry, London, England. #1111 Clinical s i g n i f i c a n c e of e l e v a t e d liver
e n z y m e s in o u t p a t i e n t s . P BertscbAnger, HP Wirth, C Meyenberger, R Flury, M Fried and W Vetter. Gastro. Unit and Med. Policlinic, Depts. of Internal Med. and Pathol., Univ. Hosp., Zurich, Switzerland.
#1112 The effect of u l t r a s o n o g r a p h y on the p e r f o r m a n c e of r o u t i n e o u t p a t i e n t liver biopsy. CI Smith and JE Grau. Digestive Healthcare, Minneapolis, MN.
#1113 S c r e e n i n g strategies for h e p a t i t i s C: m o d e l s d e r i v e d from t h e N a t i o n a l Hepatitis S u r v e i l l a n c e P r o g r a m . A Jakiche, K Lapane, D Sugano, W Weng and WD Carey. Dept. of Gastro. and Hepatol., The Cleveland Clinic Foundation, Cleveland, OH; Schering-Plough Corp., Kenilworth, NJ.
#1114 A s s e s s m e n t a n d m e d i c a l f o l l o w - u p of i n t r a v e n o u s d r u g u s e r s p o s i t i v e for h e p a t i t i s C v i r u s in N o r t h e a s t England. AM Brind, MA Serfaty, A Lawrie, JP Watson, S Johnson, E Gilvarry and MF Bassendine. Freeman Hosp. and Plummer Court, Regional Drug Dependency Unit, Newcastle-upon-Tyne, England.
AASLD PROGRAM
105A
Tuesday Posters #1101 Effect of i s c h e m i a / r e p e r f u s i o n on
h e a t - s h o c k p r o t e i n 70 a n d 90 g e n e e x p r e s s i o n in rat liver: r e l a t i o n to n u t r i t i o n a l status. A Gasbarrini, S Degli Esposti, S De Notariis, P Caraceni, S Loffredo, A Abraham, M Simoncini, A Colantoni, F Trevisani, G Gasbarrini and M Bernardi. Univ. di Bologna and Univ. Cattolica, Roma, Italy; Brown Univ., Providence, RI.
#1102 L y s o s o m a l e n z y m e s as early a n d q u a n t i t a t i v e m a r k e r s of h e p a t i c i s c h e m i a / r e p e r f u s i o n injury. W Liu, O SchSb, J Pugmire, D Jackson, KA Zucker, DE Fry and RH Glew. Dept. of Surg. and Biochem., Univ. of New Mexico, Albuquerque, NM. #1103 Effects of h e p a t o c y t e g r o w t h factor
on d i m e t h y l n i t r o s o a m i n e - i n d u c e d liver i n j u r y in rats. K Okabe, H Suzuki, S Suemori, T Yamamoto, Y Mamata, N Matsumoto, H Mizuno, M Kono, M Suga, M Suzuki, Y Kato, A Sato and T Meguro. Dept. of Internal Med. and Research Lab., Yokohama City Seibu Hosp., St. Marlanna Univ. Sch. of Med., Yokohama, Japan. #1104 I n t e r a c t i o n s of c y c l o s p o r i n e A
a n d its d e r i v a t i v e IMM-125 w i t h rat h e p a t o c y t e s . A Wolf, C Trendelenburg, L Aicher, U Schramm, A Fahr and G Fricker. Sandoz Pharma AG, Basel, Switzerland.
#1105 I n c r e a s e s in i n t r a c e l l u l a r c a l c i u m in n e u t r o p h i l s (PMNs) d u e to formylmethionine-leucine-phenylalanine a n d e n d o t o x i n are b l o c k e d completely b y glycine. RF Stachlewitz, K Ikejima and RG Thurman. Lab. of Hepatobiol. and Toxicol., Dept. of Pharmacol., Univ. of North Carolina, Chapel Hill, NC. #1106 I n d u c t i o n of t h e p e r m e a b i l i t y tran-
s i t i o n b y a g e n t s i m p l i c a t e d in Reye's s y n d r o m e a n d Reye's-like d r u g toxicity: a p o s s i b l e p a t h o g e n e s i s of mitochondrial dysfunction. LC Trost and JJ Lemasters. Dept. Cell Biol. & Anatomy and Curriculum in Toxicol., Univ. of North Carolina, Chapel Hill, NC.
#1107 S e r u m isocitrate d e h y d r o g e n a s e as a m a r k e r of c e n t r i l o b u l a r h e p a t i c n e c r o s i s in t h e e x p e r i m e n t a l m o d e l of rats. Y-H Chung, JA Kim, GS Ahn, IH Song, MS Koh, YS Lee and DJ Suh. Dept. of Internal Med. and Inst. of Life Science, Asan Med. Ctr., College of Med., Univ. of Ulsan, Seoul, Korea.
#1108 T r a n s v e n o u s liver biopsy in f u l m i n a n t , s u b f u l m i n a n t and severe acute hepatic failure. J Gournay, F Durand, C Degott, J Bernuau, S Erlinger and D Lebrec. Serv. d'Hepatol., INSERM U24 and Serv. d'Anatomie Pathol., Hop. Beaujon, Clichy, France.
PUBLIC POLICY AND EPIDEMIOLOGY
#1109 Temporal and geographical variations in the prevalence of p r i m a r y b i l i a r y cirrhosis in Northeast England. JV Metcalf, RS Bhopal, LRMD Scott, J Gray, D Howel and OFW James. Depts. of Med. and Epidemiol., Univ. of Newcastle, Newcastle-upon-Tyne, England. #1110 I m p r o v e d o u t c o m e from s e v e r e
acetaminophen-induced hepatotoxicity. AJ Makin, J Wendon and R Williams. Inst. of Liver Studies, King's College Sch. of Med. & Dentistry, London, England. #1111 Clinical s i g n i f i c a n c e of e l e v a t e d liver
e n z y m e s in o u t p a t i e n t s . P BertscbAnger, HP Wirth, C Meyenberger, R Flury, M Fried and W Vetter. Gastro. Unit and Med. Policlinic, Depts. of Internal Med. and Pathol., Univ. Hosp., Zurich, Switzerland.
#1112 The effect of u l t r a s o n o g r a p h y on the p e r f o r m a n c e of r o u t i n e o u t p a t i e n t liver biopsy. CI Smith and JE Grau. Digestive Healthcare, Minneapolis, MN.
#1113 S c r e e n i n g strategies for h e p a t i t i s C: m o d e l s d e r i v e d from t h e N a t i o n a l Hepatitis S u r v e i l l a n c e P r o g r a m . A Jakiche, K Lapane, D Sugano, W Weng and WD Carey. Dept. of Gastro. and Hepatol., The Cleveland Clinic Foundation, Cleveland, OH; Schering-Plough Corp., Kenilworth, NJ.
#1114 A s s e s s m e n t a n d m e d i c a l f o l l o w - u p of i n t r a v e n o u s d r u g u s e r s p o s i t i v e for h e p a t i t i s C v i r u s in N o r t h e a s t England. AM Brind, MA Serfaty, A Lawrie, JP Watson, S Johnson, E Gilvarry and MF Bassendine. Freeman Hosp. and Plummer Court, Regional Drug Dependency Unit, Newcastle-upon-Tyne, England.