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2201 A PET study of verbal memory retention process in human
s250
22. Memory
2201
and Learning
A PET study of verbal memory retention process in human
Section of Neuropsychology, Division of Disability Science, Tohoku University Graduate School of Medicine’, Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University2, Department of Nuclear Medicine, Cyclotron and Radioisotope Center, Tohoku University3 Jiro Okudal, Toshikatsu Fukuda2, Masatoshi Ito
Fujiil,
Nobuto
Motooka’,
Atsushi Yamadori’,
Ryuta Kawashima2,
Hiroshi
PET and “0 labeled water were used to measure regional cerebral blood flows (rCBFs) of 6 young healthy right-handed male volunteers during two tasks; i.e., a control task and an activation task. In both tasks, they heard 10 sets of 5 stimuli comprised of Japanese noun words and asked to repeat the set of stimuli orally. In addition, only in an activation task, subjects were required to memorize a list of 10 words minutes before the PET scan and asked to hold these words during the scan. Effective activation foci determined as regions of significantly increased rCBF in subtraction of the control task from the activation task were as follows; in the left hemisphere, the inferior occipital gyrus (Brodmann Area, BA 18), inferior frontal gyrus (BA 47), middle frontal gyrus (BA 9) and anterior cingulate gyrus (BA 24). In the right hemisphere, activated regions were seen in the medial frontal lobe (BA 6). Further, regions in the tale of caudate nucleus were activated bilaterally.
2202 Department
Learning of sequential saccades: A study with PET of Nuclear Medicine & Radiology, IDAC, Tohoku University
Ryuta Kawashima, Kazunori Sato, Kentaro Inoue, Hiroshi Fukuda The purpose of this study was to identify the functional fields activated in relation to learning of sequential saccadic eye movements. Nine healthy subjects participated in the study which consisted of two positron emission tomography scans. In the learning task, subjects were asked to track a sequence of seven successive positions of visual targets and to memorize order of the targets as well as spatial location of each target. In the control task, subjects were ask to track visual target which was presented randomly in location. The mean regional cerebral blood flow (rCBF) change images for task minus control were calculated and fields of significant rCBF changes were identified. Several fields in the intraparietal cortex, the prefrontal cortex and the pre-SMA were activated. The results indicate that those structures work as a part of neural network involved in sequence learning.
22. Memory
2201
and Learning
A PET study of verbal memory retention process in human
Section of Neuropsychology, Division of Disability Science, Tohoku University Graduate School of Medicine’, Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University2, Department of Nuclear Medicine, Cyclotron and Radioisotope Center, Tohoku University3 Jiro Okudal, Toshikatsu Fukuda2, Masatoshi Ito
Fujiil,
Nobuto
Motooka’,
Atsushi Yamadori’,
Ryuta Kawashima2,
Hiroshi
PET and “0 labeled water were used to measure regional cerebral blood flows (rCBFs) of 6 young healthy right-handed male volunteers during two tasks; i.e., a control task and an activation task. In both tasks, they heard 10 sets of 5 stimuli comprised of Japanese noun words and asked to repeat the set of stimuli orally. In addition, only in an activation task, subjects were required to memorize a list of 10 words minutes before the PET scan and asked to hold these words during the scan. Effective activation foci determined as regions of significantly increased rCBF in subtraction of the control task from the activation task were as follows; in the left hemisphere, the inferior occipital gyrus (Brodmann Area, BA 18), inferior frontal gyrus (BA 47), middle frontal gyrus (BA 9) and anterior cingulate gyrus (BA 24). In the right hemisphere, activated regions were seen in the medial frontal lobe (BA 6). Further, regions in the tale of caudate nucleus were activated bilaterally.
2202 Department
Learning of sequential saccades: A study with PET of Nuclear Medicine & Radiology, IDAC, Tohoku University
Ryuta Kawashima, Kazunori Sato, Kentaro Inoue, Hiroshi Fukuda The purpose of this study was to identify the functional fields activated in relation to learning of sequential saccadic eye movements. Nine healthy subjects participated in the study which consisted of two positron emission tomography scans. In the learning task, subjects were asked to track a sequence of seven successive positions of visual targets and to memorize order of the targets as well as spatial location of each target. In the control task, subjects were ask to track visual target which was presented randomly in location. The mean regional cerebral blood flow (rCBF) change images for task minus control were calculated and fields of significant rCBF changes were identified. Several fields in the intraparietal cortex, the prefrontal cortex and the pre-SMA were activated. The results indicate that those structures work as a part of neural network involved in sequence learning.