456. Precise Manipulation of a Herpesvirus for Gene Therapy

456. Precise Manipulation of a Herpesvirus for Gene Therapy

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454. An Easy Method T o Produce High Amount To Apathogenic HSV -1 Amplicon V ectors HSV-1 Vectors Cécile C. Zaupa,1 Alberto L. L. Epstein.1 1 Centre de Génétique Moléculaire et Cellulaire, CNRS-UMR 5534. Université Claude Bernard Lyon 1, Villeurbanne, France. C  "

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455. Multiple Administration of NV1020, an Oncolytic HSV -1, Results in Increased Anti-T umor Efficacy in HSV-1, Anti-Tumor Rodents with Colorectal Metastases to Liver Brian C. Horsburgh,1 Yuman Fong,2 Sandeep Malhotra,2 Keith Delman,2 Tina Rogers,3 Joanna J. Peterkin,1 Frank Tufaro.1 1 MediGene Inc, San Diego, CA, United States; 2MSKCC, New York, NY, United States; 3SRI, Birmingham, AL, United States. *.89,9    "    

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456. Precise Manipulation of a Herpesvirus for Gene Therapy Rob E. White,1 Adrian Whitehouse.1 1 Molecualar Medicine Unit, St James′s University Hospital, Leeds, United Kingdom.            

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 C.(           -2'/  2'        3  Molecular Therapy Vol. 5, No. 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy

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457. Improved Efficacy of Replication Competent Oncolytic HSV -1 V ector G47 Δ in Brain T umors HSV-1 Vector G47Δ Tumors Yasushi Ino,1 Robert L. Martuza,1 Samuel D. Rabkin,1 Tomoki Todo.1 1 Molecular Neurosurgery Laboratory, Massachusetts General Hospital, Boston, MA, United States. @        3      8 -C(."8/      

                    

   



                                       

                   

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" !"!##  458. Heparan Sulfate Proteoglycans, and Not CAR or Integrins, Are the Major Receptors for Hepatic Adenoviral T ransduction In V ivo Transduction Vivo Ted A. Smith,1 Neeraja Idamakanti,1 Patrick M. Wright,1 Jennifer Marshall-Neff,1 Michele L. Rollence,1 Glen R. Nemerow,2 Christine Mech,1 Anne Pinkstaff,1 Michele Kaloss,1 Michael Kaleko,1 Susan C. Stevenson.1 1Genetic Therapy, Inc., A Novartis Company, Gaithersburg, MD, United States; 2Department of Immunology, The Scripps Research Institute, La Jolla, CA, United States. ' E               "



                      

        

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