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4880833 Synergistic pharmaceutical compositions, their production and use
ii
New Patents
4880805
4880835
USE OF ALKYLENEDIAMINE DERIVATIVES FOR THE TREATMENT OF BLOOD FLOW DISTURBANCES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF SULINDAC
Erwin Bohm, Jens-Peter Holck, Wolfgang Kampe, Herbert Leinert, Bernd MullerBeckmann, Klaus Strein, Ladenburg, Federal Republic Of Germany assigned to Boehringer Mannheim GmbH The present invention is concerned with the use of compounds of the general formula: See Patent for Chemical Structure (I) wherein A is an optionally substituted phenyl or heteroaromatic radical, R6 and R7 are hydrogen or lower alkyl, X is an alkylene chain containing up to 6 carbon atoms, Y is a valency bond or a )C double bondO group and B is an optionally substituted phenyl or heteroaromatic radical, as well as of their pharmacologically acceptable salts for the treatment of blood flow disturbances. The present invention also provides pharmaceutical compositions which contain these compounds.
4880833 SYNERGISTIC PHARMACEUTICAL COMPOSITIONS, THEIR PRODUCTION AND USE Jozsef Knoll, Walter Birkmayer, Katalin Kalloy, Jen Marton, Zoltan Ecsery, Budapest, Hungary assigned to Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara RT The invention relates to a synergistic pharmaceutical composition, which comprises as an active ingredient a combination of 1-phenylalanine and (-)-deprenyl ((-)-N-(1 phenylisopropyl) Nmethyl N-propinylamine hydrochloride) and optionally carbidopa (3-(3, 4-dihydroxyphenyl) 2-hydrazino 2-methyl-propionic acid monohydrate) or benzerazide (N-(DL-seryl)-N'-( 2,3,4-trihydroxybenzyl) hydrazine) in association with conventional inert, non-toxic solid or liquid pharamaceutical carriers. The invention further relates to the preparation of these compositions and to the use thereof for the treatment of depressive symptoms.
Moo K Park assigned to Formulations Development Labs Inc Pharmaceutically elegant oral liquid compositions of sulindac are prepared using calcium sulindac in a vehicle comprising a glycol, a polyol, optional ethanol and pharmaceutical additives.
4882149 PHARMACEUTICAL DEPOT PREPARATION Myron Spector assigned to Ed Geistlich Sohne A G fur Chemische Industrie Pharmaceutical depot preparation for implantation into base tissue comprising natural bone mineral from which the naturally associated fat and bone-proteins have been removed whereby said bone is sterile and non-allergenic, said bone mineral having absorbed thereon and/or adsorbed therein one or more physiologically active substances. The physiologically active substance is advantageously an antibiotic or taurolidine or tauraltam or a protein or polypeptide assisting bone regeneration.
4882315 AMINOGLYCOSIDE STEROIDS, A PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Laura Chiodini, Mauro Gobbini, Sergio Mantegani, Daniel Ruggieri, Aldemio Temperilli, Gabriella Traquandi, Patrizia Ferrari, Busto Arsizio, Italy assigned to Farmitalia Carlo Erba
SpA See Patent for Chemical Structure I Compounds I (either R1--OH, C1-C4 alkoxy and R 2 = H , C1-C4 alkyl, or R l + R 2 f f i a chemical bond; R 3 = a n aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being alpha or beta)
New Patents
4880805
4880835
USE OF ALKYLENEDIAMINE DERIVATIVES FOR THE TREATMENT OF BLOOD FLOW DISTURBANCES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF SULINDAC
Erwin Bohm, Jens-Peter Holck, Wolfgang Kampe, Herbert Leinert, Bernd MullerBeckmann, Klaus Strein, Ladenburg, Federal Republic Of Germany assigned to Boehringer Mannheim GmbH The present invention is concerned with the use of compounds of the general formula: See Patent for Chemical Structure (I) wherein A is an optionally substituted phenyl or heteroaromatic radical, R6 and R7 are hydrogen or lower alkyl, X is an alkylene chain containing up to 6 carbon atoms, Y is a valency bond or a )C double bondO group and B is an optionally substituted phenyl or heteroaromatic radical, as well as of their pharmacologically acceptable salts for the treatment of blood flow disturbances. The present invention also provides pharmaceutical compositions which contain these compounds.
4880833 SYNERGISTIC PHARMACEUTICAL COMPOSITIONS, THEIR PRODUCTION AND USE Jozsef Knoll, Walter Birkmayer, Katalin Kalloy, Jen Marton, Zoltan Ecsery, Budapest, Hungary assigned to Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara RT The invention relates to a synergistic pharmaceutical composition, which comprises as an active ingredient a combination of 1-phenylalanine and (-)-deprenyl ((-)-N-(1 phenylisopropyl) Nmethyl N-propinylamine hydrochloride) and optionally carbidopa (3-(3, 4-dihydroxyphenyl) 2-hydrazino 2-methyl-propionic acid monohydrate) or benzerazide (N-(DL-seryl)-N'-( 2,3,4-trihydroxybenzyl) hydrazine) in association with conventional inert, non-toxic solid or liquid pharamaceutical carriers. The invention further relates to the preparation of these compositions and to the use thereof for the treatment of depressive symptoms.
Moo K Park assigned to Formulations Development Labs Inc Pharmaceutically elegant oral liquid compositions of sulindac are prepared using calcium sulindac in a vehicle comprising a glycol, a polyol, optional ethanol and pharmaceutical additives.
4882149 PHARMACEUTICAL DEPOT PREPARATION Myron Spector assigned to Ed Geistlich Sohne A G fur Chemische Industrie Pharmaceutical depot preparation for implantation into base tissue comprising natural bone mineral from which the naturally associated fat and bone-proteins have been removed whereby said bone is sterile and non-allergenic, said bone mineral having absorbed thereon and/or adsorbed therein one or more physiologically active substances. The physiologically active substance is advantageously an antibiotic or taurolidine or tauraltam or a protein or polypeptide assisting bone regeneration.
4882315 AMINOGLYCOSIDE STEROIDS, A PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Laura Chiodini, Mauro Gobbini, Sergio Mantegani, Daniel Ruggieri, Aldemio Temperilli, Gabriella Traquandi, Patrizia Ferrari, Busto Arsizio, Italy assigned to Farmitalia Carlo Erba
SpA See Patent for Chemical Structure I Compounds I (either R1--OH, C1-C4 alkoxy and R 2 = H , C1-C4 alkyl, or R l + R 2 f f i a chemical bond; R 3 = a n aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being alpha or beta)