- Email: [email protected]
4983515 Labeled cryopreserved cells for use as targets in cytotoxicity assays
PATENT ABSTRACTS
296 4983511
4983516
METHOD AND KIT FOR DETECTING LIVE MICROORGANISMS IN CHLORINE- OR BROMINETREATED WATER
BIOELECTROCHEMICAL MEASUREMENT OF MICROBIAL ACTIVITY USING A WORKING ELECTRODE OF CARBONBEARING POROUS MATERIAL
Jon R Geiger, Jayne F Carney, Katherine P Roberts assigned to Olin Corporation
Anthony P F Turner, Alan P Hodges, An Franklin, Graham Ramsay, Davina Steel, Cranfield, United Kingdom assigned to Paul De La Pena Limited
Water monitoring systems, and more specifically, to a method and kit for detecting the presence of only living undesirable or indicator microorganisms in water after treatment of the water with chlorine or bromine.
4983513 SULFHYDRYL COMPOUNDS FOR SUPPRESSING THE INHIBITORY EFFECTS OF NAD DEGRADATION PRODUCTS ON LD-L ACTIVITY Tsung-I Lin, Alice C Liu assigned to Beckman Instruments Inc A liquid coenzyme reagent comprises the coenzyme nicotinamide adenine dinucleotide (NAD), or nicotinamide adenine dinucleotide phosphate (NADP), and a sulfhydryl compound capable of counteracting the inhibitory effects of NAD (or NADP) degradation products on LD-L activity. The reagent is maintained at a pH of less than about 31/2. The liquid reagent has a shelf life of at least about 2 years, maintaining a LD-L activity of at least 90% that of the reagent when fresh, when stored at a temperature of from 2 degrees-8 degrees C.
4983515 LABELED CRYOPRESERVED CELLS FOR USE AS TARGETS IN CYTOTOXICITY ASSAYS Derrick T Maley, Agneta K Nordstrom assigned to E I du Pont de Nemours and Company Biological cells which are fluorophore-labeled can be stored frozen for a long period of time. After thawing the cells can be used as targets in fluorophore-release cytotoxicity assays.
Microbial activity in an aqueous medium is measured in a bioelectrochemical cell in which the working electrode comprises an electrically conductive carbon-bearing porous material; suitably a graphitized carbon felt or cloth. This enhances the BEC response by increasing the surface area and by absorbing microbes onto the surface; and the electrode material can also be used to preconcentrate the microbes prior to use as an electrode in the cell. 4983530 SANDWICH IMMUNOASSAY FOR DETERMINATION OF TOTAL MONOCLONAL IGG Charles W Carlson assigned to E I Du Pont de Nemours and Company A sandwich immunoassay for determining total monoclonal IgG content in samples of purified IgG, cell culture medium and ascites fluid is provided based on the utilization of anti-light-chain IgG antibodies as both capture and label antibodies. 4983756 NOVEL CHOLINE DERIVATIVE AND METHOD FOR DETEMINING SERUM CHOLINESTERASE ACTIVITY USING THE SAME Katsumasa Kuriowa, Katsuhiro Katayama, Takeshi Nagasawa, Kofiyama, Japan assigned to Nitro Boseki Co Ltd A novel compound, 6-acetoxymethyl- 2naphthoylcholine halide, is very stable to nonenzymatic hydrolysis and react specifically with cholinesterase in serum. A UV method for determining cholinesterase activity in serum which uses the novel compound as a substrate permits very accurate and highly reproducible determination of cholinesterase activity in serum, and .therefor is very useful for clinical examination.
296 4983511
4983516
METHOD AND KIT FOR DETECTING LIVE MICROORGANISMS IN CHLORINE- OR BROMINETREATED WATER
BIOELECTROCHEMICAL MEASUREMENT OF MICROBIAL ACTIVITY USING A WORKING ELECTRODE OF CARBONBEARING POROUS MATERIAL
Jon R Geiger, Jayne F Carney, Katherine P Roberts assigned to Olin Corporation
Anthony P F Turner, Alan P Hodges, An Franklin, Graham Ramsay, Davina Steel, Cranfield, United Kingdom assigned to Paul De La Pena Limited
Water monitoring systems, and more specifically, to a method and kit for detecting the presence of only living undesirable or indicator microorganisms in water after treatment of the water with chlorine or bromine.
4983513 SULFHYDRYL COMPOUNDS FOR SUPPRESSING THE INHIBITORY EFFECTS OF NAD DEGRADATION PRODUCTS ON LD-L ACTIVITY Tsung-I Lin, Alice C Liu assigned to Beckman Instruments Inc A liquid coenzyme reagent comprises the coenzyme nicotinamide adenine dinucleotide (NAD), or nicotinamide adenine dinucleotide phosphate (NADP), and a sulfhydryl compound capable of counteracting the inhibitory effects of NAD (or NADP) degradation products on LD-L activity. The reagent is maintained at a pH of less than about 31/2. The liquid reagent has a shelf life of at least about 2 years, maintaining a LD-L activity of at least 90% that of the reagent when fresh, when stored at a temperature of from 2 degrees-8 degrees C.
4983515 LABELED CRYOPRESERVED CELLS FOR USE AS TARGETS IN CYTOTOXICITY ASSAYS Derrick T Maley, Agneta K Nordstrom assigned to E I du Pont de Nemours and Company Biological cells which are fluorophore-labeled can be stored frozen for a long period of time. After thawing the cells can be used as targets in fluorophore-release cytotoxicity assays.
Microbial activity in an aqueous medium is measured in a bioelectrochemical cell in which the working electrode comprises an electrically conductive carbon-bearing porous material; suitably a graphitized carbon felt or cloth. This enhances the BEC response by increasing the surface area and by absorbing microbes onto the surface; and the electrode material can also be used to preconcentrate the microbes prior to use as an electrode in the cell. 4983530 SANDWICH IMMUNOASSAY FOR DETERMINATION OF TOTAL MONOCLONAL IGG Charles W Carlson assigned to E I Du Pont de Nemours and Company A sandwich immunoassay for determining total monoclonal IgG content in samples of purified IgG, cell culture medium and ascites fluid is provided based on the utilization of anti-light-chain IgG antibodies as both capture and label antibodies. 4983756 NOVEL CHOLINE DERIVATIVE AND METHOD FOR DETEMINING SERUM CHOLINESTERASE ACTIVITY USING THE SAME Katsumasa Kuriowa, Katsuhiro Katayama, Takeshi Nagasawa, Kofiyama, Japan assigned to Nitro Boseki Co Ltd A novel compound, 6-acetoxymethyl- 2naphthoylcholine halide, is very stable to nonenzymatic hydrolysis and react specifically with cholinesterase in serum. A UV method for determining cholinesterase activity in serum which uses the novel compound as a substrate permits very accurate and highly reproducible determination of cholinesterase activity in serum, and .therefor is very useful for clinical examination.