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5261403 Magnetic resonance imaging apparatus
XXIX
New Patents porting the first end-portion of the inner holder. Also, a spinning apparatus having: an inner holder for the sample; mechanism for spinning the inner holder, while positioned in a magnetic field, about its axis; a first and second bearing for supporting, respectively, a first and second endportion of the inner holder; an outer housing for retaining the inner holder; mechanism for spinning the outer housing about its axis; and a substantially nonmagnetic mechanical third bearing for supporting the right end-portion of the outer housing. Also included is a device for measuring the magnetic resonance spectrum of a sample.
trically conductive member to form a single coil. NMR signals can be detected at a high sensitivity, enabling an image of a high S/N ratio and measurement of a wide detection region.
5261405 APPARATUS AND METHOD FOR DETECTING CANCER USING NUCLEAR MAGNETIC RESONANCE Eric T Fossel assigned Hospital Association
to
The
Beth
Israel
5260658
A circuit for detuning a resonator in a nuclear magnetic resonance imaging apparatus has an output connected to a terminal of the resonator via a high-frequency line composed of two conductors. The resonator is shortened at this terminal with a shorting capacitor that can be short-circuited for detuning the resonator. The length of the high-frequency line is shorter than one-fourth of the wavelength of a highfrequency signal having the operating frequency of the nuclear magnetic resonance imaging apparatus on the high-frequency line. For detuning the resonator the high-frequency line can be terminated at the output with a further capacitor, so that the high-frequency line acts as a shortcircuit at the terminal.
A technique and an apparatus are disclosed for the detection of cancer using nuclear magnetic resonance (NMR). Specifically, NMR parameters for protons of lipid methyl and/or methylene groups are determined and compared against a corresponding value for healthy patients. In the preferred embodiments, an improved NMR spectrometer is employed to provide a spectrum for non-water components of blood, blood serum or blood plasma and the width of the methyl and/or methylene groups is automatically measured at half-height as a determination of spin-spin relaxation time (T2) which is the parameter used for purposes of comparison with healthy controls. Suppression of the water proton signal is employed where necessary in order to obtain a suitable spectrum for the non-water component protons. In the event that a positive reading is obtained, the level of plasma triglycerides is determined and if it is high, the patient’s bodily fluid sample is further subjected to C-l 3 nuclear magnetic spectroscopy. The resonance line of the plasma C- 13 spectra discriminates between true and false positive results from the proton NMR reading and determines the presence or absence of cancer in the patient.
5261403
5262532
MAGNETIC RESONANCE IMAGING APPARATUS
PARAMAGNETIC METALLOPORPHYRINS AS CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING
DETUNING CIRCUIT FOR RESONATORS IN A NUCLEAR MAGNETIC RESONANCE IMAGING APPARATUS Helmu Greim, Juerge Ruhl, Ralp Oppelt, Adelsdorf, Federal Republic Of Germany assigned to Siemens Aktiengesellschaft
Minoru Ibaraki,
Saito, Toshihir Ishizuka, Yasuo Wada, Japan assigned to Hitachi Ltd
In an MR imaging apparatus, a receiving coil comprising an upper coil and a lower coil which jointly sandwitch a desired part of a body to be inspected in an openable and closable manner, the upper and the lower coils being connected by connection means comprised of flexible and elec-
Michael Tweedle, Lon J Wilson, Joseph Bradshaw, Daniel W Lee assigned to E R Squibb & Sons Inc Porphyrin-complex compounds useful as contrast agents in magnetic resonance imaging
New Patents porting the first end-portion of the inner holder. Also, a spinning apparatus having: an inner holder for the sample; mechanism for spinning the inner holder, while positioned in a magnetic field, about its axis; a first and second bearing for supporting, respectively, a first and second endportion of the inner holder; an outer housing for retaining the inner holder; mechanism for spinning the outer housing about its axis; and a substantially nonmagnetic mechanical third bearing for supporting the right end-portion of the outer housing. Also included is a device for measuring the magnetic resonance spectrum of a sample.
trically conductive member to form a single coil. NMR signals can be detected at a high sensitivity, enabling an image of a high S/N ratio and measurement of a wide detection region.
5261405 APPARATUS AND METHOD FOR DETECTING CANCER USING NUCLEAR MAGNETIC RESONANCE Eric T Fossel assigned Hospital Association
to
The
Beth
Israel
5260658
A circuit for detuning a resonator in a nuclear magnetic resonance imaging apparatus has an output connected to a terminal of the resonator via a high-frequency line composed of two conductors. The resonator is shortened at this terminal with a shorting capacitor that can be short-circuited for detuning the resonator. The length of the high-frequency line is shorter than one-fourth of the wavelength of a highfrequency signal having the operating frequency of the nuclear magnetic resonance imaging apparatus on the high-frequency line. For detuning the resonator the high-frequency line can be terminated at the output with a further capacitor, so that the high-frequency line acts as a shortcircuit at the terminal.
A technique and an apparatus are disclosed for the detection of cancer using nuclear magnetic resonance (NMR). Specifically, NMR parameters for protons of lipid methyl and/or methylene groups are determined and compared against a corresponding value for healthy patients. In the preferred embodiments, an improved NMR spectrometer is employed to provide a spectrum for non-water components of blood, blood serum or blood plasma and the width of the methyl and/or methylene groups is automatically measured at half-height as a determination of spin-spin relaxation time (T2) which is the parameter used for purposes of comparison with healthy controls. Suppression of the water proton signal is employed where necessary in order to obtain a suitable spectrum for the non-water component protons. In the event that a positive reading is obtained, the level of plasma triglycerides is determined and if it is high, the patient’s bodily fluid sample is further subjected to C-l 3 nuclear magnetic spectroscopy. The resonance line of the plasma C- 13 spectra discriminates between true and false positive results from the proton NMR reading and determines the presence or absence of cancer in the patient.
5261403
5262532
MAGNETIC RESONANCE IMAGING APPARATUS
PARAMAGNETIC METALLOPORPHYRINS AS CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING
DETUNING CIRCUIT FOR RESONATORS IN A NUCLEAR MAGNETIC RESONANCE IMAGING APPARATUS Helmu Greim, Juerge Ruhl, Ralp Oppelt, Adelsdorf, Federal Republic Of Germany assigned to Siemens Aktiengesellschaft
Minoru Ibaraki,
Saito, Toshihir Ishizuka, Yasuo Wada, Japan assigned to Hitachi Ltd
In an MR imaging apparatus, a receiving coil comprising an upper coil and a lower coil which jointly sandwitch a desired part of a body to be inspected in an openable and closable manner, the upper and the lower coils being connected by connection means comprised of flexible and elec-
Michael Tweedle, Lon J Wilson, Joseph Bradshaw, Daniel W Lee assigned to E R Squibb & Sons Inc Porphyrin-complex compounds useful as contrast agents in magnetic resonance imaging