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A Note of Thanks
Clinical Therapeutics/Volume 36, Number 12, 2014
A NOTE OF THANKS Peer review is the lifeblood of scientific publishing. To maintain the highest standards for the content of manuscripts published in Clinical Therapeutics, we seek independent reviewers from the faculties of medical schools and schools of pharmacy worldwide. Not only are our reviewers asked to provide in-depth reviews, but they are asked to do so within a short period of time. Clinical Therapeutics wishes to thank the following individuals for sharing their time and expertise this year in our ongoing effort to strengthen the peer-review process:
Zanfina Ademi, MPharm, MPH, PhD Anil Agarwal, MD Marco Ajelli Emmanuel O. Akala, RPh, PhD Cesar Alaniz, PharmD Arnie Aldridge Barbara T. Alexander Badraddin M. Al-Hadiya, PhD Karel Allegaert Giorgio Amaldi Guohua An David Andrae, PhD Wilbert S. Aronow, MD Daniel Austin, PharmD Christina Azevedo David Back Kevin T. Bain, Pharm.D., MPH, BCPS, CGP, CPH George Bakalos, MSc, MD Rajesh Balkrishnan, PhD Benjamin Banderas Robert Barkin, PharmD Jens Malte Baron, MD Lena Barrera Daniel Bar-Shalom Joshua I. Barzilay, MD Sharon Dawn Bateman Marisa Battistella Seth Mark Berney, MD Kirthana R. Beaulac, PharmD Michael H. Beck Edward Bednarczyk Paul Beninger, MD, MBA Charles Bennett, MD, PhD, MPP Sergio Daniel Bergese Martin Jan Bergman, MD, FACR, FACP Gaetano Bertino, MD Palash Bhattacharya, PhD Douglas L. Boggs, PharmD, MS, BCPP Farasat Bokhari Vijayveer Bonthapally, PhD David W. Boulton, PhD Walter R. Bowles, PhD, DDS, MS, BPharm Kathleen E. Boyle, PhD Heddwen Brooks, PhD Kevin Brown Susan Bruce, PharmD, BCPS Marilyn N. Bulloch, PharmD, BCPS Michael Bursztyn Valerie Buthion William David Cahoon, Jr., PharmD, BCPS Grant Cannon
A8
Joseph C. Cappelleri, PhD, MPH Michael Carrithers Anthony Casapao, PharmD Marcel J. Casavant, MD Willi Cawello Engin Çekin, MD Jie Chen, PhD Wen-Hung Chen, PhD Yao Chen, PhD Eileen Chichin Lindsey Childs-Kean, PharmD, MPH, BCPS Leslie Citrome, MD, MPH Dario Cocito Craig Coleman, PharmD Andrea Corsonello Jerry Cott, PhD Burke A. Cunha, MD Adamasco Cupisti, MD Robert B. Den, MD Julie Ann Dopheide, PharmD, BCPP Susan dos Reis John Doyle George Dranitsaris, PhD Manal M. El Behery, MD Cigdem Kalaycik Ertugay Gohar Eslami, PharmD Tom P. Fahey Suzanne Falck, MD Christine E. Farkas, PharmD, BCPP Paolo Ferrari, MBBS, MD James Stuart Ferriss, MD Emanuela Foglia Graeme Forrest William H. Frishman, MD Reginald Frye Stephen Fuller, MBBS, PhD, FRACP, FRCPA Joshua Gagne, PharmD, ScD Ivan Gentile, MD F. Wilford Germino, MD M. Eric Gershwin, MD Kenneth Getz, MBA Ellie C.J. Goldstein Kim Gombert-Handoko, PharmD, PhD Nate Gorney, PharmD, BCPS Allan Gottschalk Christopher J. Graber Chris Graham Mitchell H. Grayson, MD Ellen P. Green, PhD David J. Greenblatt, MD Andreas H. Groll
Volume 36 Number 12
Clinical Therapeutics Hongqian Guo, MD Sandeep Kumar Gupta, MD Bill J. Gurley, PhD Ronald G. Hall, PharmD, MSCS Guy Henri Hans, MD, PhD Mary Elizabeth Hanson, PhD Leslie K. Hasche, PhD, MSW Brett Hauber, PhD Ron D. Hays, PhD Khedidja Hedna Marie François Heymann, MD Paul Hjemdahl Masatsugu Hori Weng-Foung Huang, PhD Alastair James Hutchison Volker R. Jacobs Michael Jann, PharmD Xiling Jiang, PhD Kyoungrae Jung, PhD Joshua Tolkien Kantrowitz, MD Jason H. Karnes, PharmD, PhD Michael B. Kays, PharmD, FCCP Gregory Kearns, PharmD, PhD Jeong Kyung Kim, MD, PhD Sang-Hyun Kim, MD, PhD Kenneth P. Klinker, PharmD Ralf Kohnen, PhD Gideon Koren, MD Joan Korth-Bradley, PharmD, PhD Michael A. Kortt, PhD Dru Krishnan, MD Henry Krum, PhD, FRACP Dirk Kuypers, MD, PhD Jin-Won Kwon Vishal Lamba, PhD Joseph Michael Lane Taimour Langaee, MS Denys T. Lau, PhD Carl J. Lavie J. Bradley Layton, PhD Carlo Lazzaro Van Le Vivan W.Y. Lee, PharmD Slivana Leite Steven Leonard Wojciech Leppert, MD, PhD Donald Levine, MD Janet Lewis, MD Gregory Lip, MD Dong-yang Liu Yun P. Liu, PhD Yoon Kong Loke, MBBS, MD Vera Lucia Luiza, ScD Brian Lund Jason Lundy, PhD Charles Mahan, PharmD Elena M. Massarotti, MD Peter Matzneller, MD Lynne V. McFarland
December 2014
Aimee L. McRae-Clark, PharmD Kari A. Mergenhagen, PharmD Mohamed-Eslam Mohamed, PhD Robert Moore Anna Morin, PharmD Bart Jan Morlion, MD, PhD Robert Morlock, PhD Alejandro Nava-Ocampo Nancy Neil, PhD Ernest Ng, MD Mark Nidorf, MD Peter Niemegeers, MD Lucien Noens, MD, PhD Daryn K. Norwood, PharmD, BCPP, BCPS, CGP John Oates Robert L. Ohsfeldt, PhD John J. Oppenheimer, MD Luis Ostrosky-Zeichner, MD, FACP, FIDSA Huang-Tz Ou Andrew Palmer Emma Palmer, PharmD Byung-Joo Park, PhD, MD, MPH Kennerly S. Patrick, PhD Elizabeth Pelkofski Charles Peloquin, PharmD Joseph V. Pergolizzi, MD Joanna Peris Vlado Perkovic, MBBS, PhD, FRACP, FASN Kevin Pile Robert S. Pinals, MD Daniele Piovani Thomas Polasek Hari Polenakovik, MD Piero Poletti David Reed Powell, MD Jason Prosek, MD Zebunnissa Ramtoola, PhD Alan Rathbun, PhD, MPH Diane B. Re, PhD Lars Rejnmark, MD, PhD, DMSc Earle John Reome, PharmD David B. Ridley, PhD Adelaide S. Robb, MD Adriana Rosato, PhD Richard M. Rosenfeld J. Mark Ruscin, PharmD, BCPS Naomi Sacks, PhD Carl Salzman Kathryn Sandberg, PhD Shingo Seki Brian Shepler, PharmD Bentao Shi Devada Singh-Franco, RPh, PharmD Ashish Sinha Stewart Siskin, PharmD Tracy Lynne Skaer, BPharm, PharmD, FASCP Dawn Smilek Alex Smith Gordon Smith
A9
A10 Tadashi Sofue, MD, PhD Craig Solid Edoardo Spina Michele Y. Splinter, PharmD, MS David B Stewart, MD Bruce Stuart, PhD Anne Taegtmeyer Derek Tang, PhD, BSPharm Hitomi Teramachi Angus Thompson Guy Thwaites Brian Tomlinson, MD Christine Toye, PhD Robert van der Stichele Stefan Vegter, PharmD, PhD Stacy A. Voils, PharmD, MS Gary Alan Walco, PhD Guoying Wang, MD, PhD Meng-Ting Wang
Acknowledgment Xinwen Wang Rukshen Weerasooriya, MBBS Brian James Werth, PharmD Lloyd R. Whitfield, PhD Michael Wong, MD Adam Wright Claire Xu, MD, PhD Chao Xu, PhD Suayib Yalcin Leslie Lee Yee, PharmD Lakshmana Kumar Yerneni, MSc, PhD Marcos Zervos Songmao Zheng, PhD Yijie Zheng, PhD, MD Jie Zhou, PhD Zheng-Yi Zhou, MS Hong Zhu Marya Zilberberg Hanneke Zwikker
Volume 36 Number 12
A NOTE OF THANKS Peer review is the lifeblood of scientific publishing. To maintain the highest standards for the content of manuscripts published in Clinical Therapeutics, we seek independent reviewers from the faculties of medical schools and schools of pharmacy worldwide. Not only are our reviewers asked to provide in-depth reviews, but they are asked to do so within a short period of time. Clinical Therapeutics wishes to thank the following individuals for sharing their time and expertise this year in our ongoing effort to strengthen the peer-review process:
Zanfina Ademi, MPharm, MPH, PhD Anil Agarwal, MD Marco Ajelli Emmanuel O. Akala, RPh, PhD Cesar Alaniz, PharmD Arnie Aldridge Barbara T. Alexander Badraddin M. Al-Hadiya, PhD Karel Allegaert Giorgio Amaldi Guohua An David Andrae, PhD Wilbert S. Aronow, MD Daniel Austin, PharmD Christina Azevedo David Back Kevin T. Bain, Pharm.D., MPH, BCPS, CGP, CPH George Bakalos, MSc, MD Rajesh Balkrishnan, PhD Benjamin Banderas Robert Barkin, PharmD Jens Malte Baron, MD Lena Barrera Daniel Bar-Shalom Joshua I. Barzilay, MD Sharon Dawn Bateman Marisa Battistella Seth Mark Berney, MD Kirthana R. Beaulac, PharmD Michael H. Beck Edward Bednarczyk Paul Beninger, MD, MBA Charles Bennett, MD, PhD, MPP Sergio Daniel Bergese Martin Jan Bergman, MD, FACR, FACP Gaetano Bertino, MD Palash Bhattacharya, PhD Douglas L. Boggs, PharmD, MS, BCPP Farasat Bokhari Vijayveer Bonthapally, PhD David W. Boulton, PhD Walter R. Bowles, PhD, DDS, MS, BPharm Kathleen E. Boyle, PhD Heddwen Brooks, PhD Kevin Brown Susan Bruce, PharmD, BCPS Marilyn N. Bulloch, PharmD, BCPS Michael Bursztyn Valerie Buthion William David Cahoon, Jr., PharmD, BCPS Grant Cannon
A8
Joseph C. Cappelleri, PhD, MPH Michael Carrithers Anthony Casapao, PharmD Marcel J. Casavant, MD Willi Cawello Engin Çekin, MD Jie Chen, PhD Wen-Hung Chen, PhD Yao Chen, PhD Eileen Chichin Lindsey Childs-Kean, PharmD, MPH, BCPS Leslie Citrome, MD, MPH Dario Cocito Craig Coleman, PharmD Andrea Corsonello Jerry Cott, PhD Burke A. Cunha, MD Adamasco Cupisti, MD Robert B. Den, MD Julie Ann Dopheide, PharmD, BCPP Susan dos Reis John Doyle George Dranitsaris, PhD Manal M. El Behery, MD Cigdem Kalaycik Ertugay Gohar Eslami, PharmD Tom P. Fahey Suzanne Falck, MD Christine E. Farkas, PharmD, BCPP Paolo Ferrari, MBBS, MD James Stuart Ferriss, MD Emanuela Foglia Graeme Forrest William H. Frishman, MD Reginald Frye Stephen Fuller, MBBS, PhD, FRACP, FRCPA Joshua Gagne, PharmD, ScD Ivan Gentile, MD F. Wilford Germino, MD M. Eric Gershwin, MD Kenneth Getz, MBA Ellie C.J. Goldstein Kim Gombert-Handoko, PharmD, PhD Nate Gorney, PharmD, BCPS Allan Gottschalk Christopher J. Graber Chris Graham Mitchell H. Grayson, MD Ellen P. Green, PhD David J. Greenblatt, MD Andreas H. Groll
Volume 36 Number 12
Clinical Therapeutics Hongqian Guo, MD Sandeep Kumar Gupta, MD Bill J. Gurley, PhD Ronald G. Hall, PharmD, MSCS Guy Henri Hans, MD, PhD Mary Elizabeth Hanson, PhD Leslie K. Hasche, PhD, MSW Brett Hauber, PhD Ron D. Hays, PhD Khedidja Hedna Marie François Heymann, MD Paul Hjemdahl Masatsugu Hori Weng-Foung Huang, PhD Alastair James Hutchison Volker R. Jacobs Michael Jann, PharmD Xiling Jiang, PhD Kyoungrae Jung, PhD Joshua Tolkien Kantrowitz, MD Jason H. Karnes, PharmD, PhD Michael B. Kays, PharmD, FCCP Gregory Kearns, PharmD, PhD Jeong Kyung Kim, MD, PhD Sang-Hyun Kim, MD, PhD Kenneth P. Klinker, PharmD Ralf Kohnen, PhD Gideon Koren, MD Joan Korth-Bradley, PharmD, PhD Michael A. Kortt, PhD Dru Krishnan, MD Henry Krum, PhD, FRACP Dirk Kuypers, MD, PhD Jin-Won Kwon Vishal Lamba, PhD Joseph Michael Lane Taimour Langaee, MS Denys T. Lau, PhD Carl J. Lavie J. Bradley Layton, PhD Carlo Lazzaro Van Le Vivan W.Y. Lee, PharmD Slivana Leite Steven Leonard Wojciech Leppert, MD, PhD Donald Levine, MD Janet Lewis, MD Gregory Lip, MD Dong-yang Liu Yun P. Liu, PhD Yoon Kong Loke, MBBS, MD Vera Lucia Luiza, ScD Brian Lund Jason Lundy, PhD Charles Mahan, PharmD Elena M. Massarotti, MD Peter Matzneller, MD Lynne V. McFarland
December 2014
Aimee L. McRae-Clark, PharmD Kari A. Mergenhagen, PharmD Mohamed-Eslam Mohamed, PhD Robert Moore Anna Morin, PharmD Bart Jan Morlion, MD, PhD Robert Morlock, PhD Alejandro Nava-Ocampo Nancy Neil, PhD Ernest Ng, MD Mark Nidorf, MD Peter Niemegeers, MD Lucien Noens, MD, PhD Daryn K. Norwood, PharmD, BCPP, BCPS, CGP John Oates Robert L. Ohsfeldt, PhD John J. Oppenheimer, MD Luis Ostrosky-Zeichner, MD, FACP, FIDSA Huang-Tz Ou Andrew Palmer Emma Palmer, PharmD Byung-Joo Park, PhD, MD, MPH Kennerly S. Patrick, PhD Elizabeth Pelkofski Charles Peloquin, PharmD Joseph V. Pergolizzi, MD Joanna Peris Vlado Perkovic, MBBS, PhD, FRACP, FASN Kevin Pile Robert S. Pinals, MD Daniele Piovani Thomas Polasek Hari Polenakovik, MD Piero Poletti David Reed Powell, MD Jason Prosek, MD Zebunnissa Ramtoola, PhD Alan Rathbun, PhD, MPH Diane B. Re, PhD Lars Rejnmark, MD, PhD, DMSc Earle John Reome, PharmD David B. Ridley, PhD Adelaide S. Robb, MD Adriana Rosato, PhD Richard M. Rosenfeld J. Mark Ruscin, PharmD, BCPS Naomi Sacks, PhD Carl Salzman Kathryn Sandberg, PhD Shingo Seki Brian Shepler, PharmD Bentao Shi Devada Singh-Franco, RPh, PharmD Ashish Sinha Stewart Siskin, PharmD Tracy Lynne Skaer, BPharm, PharmD, FASCP Dawn Smilek Alex Smith Gordon Smith
A9
A10 Tadashi Sofue, MD, PhD Craig Solid Edoardo Spina Michele Y. Splinter, PharmD, MS David B Stewart, MD Bruce Stuart, PhD Anne Taegtmeyer Derek Tang, PhD, BSPharm Hitomi Teramachi Angus Thompson Guy Thwaites Brian Tomlinson, MD Christine Toye, PhD Robert van der Stichele Stefan Vegter, PharmD, PhD Stacy A. Voils, PharmD, MS Gary Alan Walco, PhD Guoying Wang, MD, PhD Meng-Ting Wang
Acknowledgment Xinwen Wang Rukshen Weerasooriya, MBBS Brian James Werth, PharmD Lloyd R. Whitfield, PhD Michael Wong, MD Adam Wright Claire Xu, MD, PhD Chao Xu, PhD Suayib Yalcin Leslie Lee Yee, PharmD Lakshmana Kumar Yerneni, MSc, PhD Marcos Zervos Songmao Zheng, PhD Yijie Zheng, PhD, MD Jie Zhou, PhD Zheng-Yi Zhou, MS Hong Zhu Marya Zilberberg Hanneke Zwikker
Volume 36 Number 12