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A proposed classification of benign tumours of adipose tissue
194
ROYAL COLLEGE OF PATHOLOGISTS OF AUSTRALIA
Pathology (1978), 10, April
communicated with bronchi proximally and with alveoli distally suggesting bronchiolectasis. However, there was also proliferation of bronchiolar structures, shown by their increase in number and by papillary overgrowth of the lining epithelium. Bronchiolar proliferation is also a feature of adenomatoid malformation. The 2 terms therefore, may possibly apply to different degrees of the same anomaly, a severe one producing stillbirth or neonatal death, and a milder one allowing survival long enough for successful surgical resection. One third of the children were full-term neonates. one third were aged 1 to 12 mth, and one third I to 10 yr. Fifteen of the specimens were surgical and 4 were necropsies. Half also had emphysema in the affected lobe, and 4 had associated extra lobar sequestration. None was associated with cysts in other organs. Radiologically and macroscopically. the overdistended lobe sometimes mimicked congenital lobar emphysema. All cases with more than focal chronic inflammation were omitted, in order to exclude post inflammatory pneumatoceles. Intrapulmonary bronchogenic cysts and intrapulmonary sequestrations differed in being usually single, often having cartilage and inflammatory fibrosis in their walls, and not having alveoli budding off the cyst. REACTION AGAINST ACTINICALLY-DAMAGED ELASTIN AS A BASIS OF TEMPORAL ARTERlTlS AND INTERNAL VASCULAR DISEASE
O'BRIEK. JOHN P. Medical Centre, Randwick. New Snutli Wales Evidence will be presented indicating the 'age change' and arteritis of the temporal artery are due to actinic damage. I t follows that the internal manifestations of the temporal arteritis/polymyalgia rheumatica syndrome, including its internal vascular complications. might likewise be due. albeit indirectly, to the same actinic cause. A PROPOSED CLASSIFICATION OF BENIGN TUMOURS OF ADIPOSE TISSUE ALLEN.P. W. Insriiuie o / Medicul & Veterinary Science Brunch Luhoraiory, Mount Gambier,
south Ausrruliu Benign fatty tumours fall into one of 5 groups; pure lipomas. benign mixed mesenchymal tumours of adipose tissue, hibernomas, lipoblastomas. and lipomatoses. Pure lipomas can be subdivided into solitary and multiple subcutaneous lipomas, and lipomas of other sites. Benign mixed mesenchymal tumours of adipose tissue can be subdivided into subcutaneous angiolipomas, including solitary. multiple. and multiple familial subcutaneous angiolipomas; subcutaneous fibrolipomas; subcutaneous myxolipomas: subcutaneous chondrolipomas; subcutaneous osteolipomas; mixtures of the preceding types: subcutaneous atypical fibrolipomas; subcutaneous spindle cell lipomas; intramuscular angiolipomas (haemangiomas of skeletal muscle); renal angiomyolipomas; and adrenal and presacral myelolipomas. It is suggested that the subcutaneous tissue is a topographic region in its own right, and that subcutaneous tumours should be considered separately from tumours of the deeper soft tissue. 'THE ESKIMOMA'-AN
UNUSUAL MALIGNANT SALIVARY GLAND TUMOUR
W. Parholog), Departnient. Royal Women'.e Hospital, Brishane Four cases of an unusual salivary gland tumour presented at the Health Science Centre, Winnipeg, Canada during a 5-yr period. from 1971 to 1976. This distinctive tumour was first described in 1963 when 9 cases were identified; 7 further cases were presented from Alaska in 1972. So far. the tumour appears to be confined to the Eskimo and to only involve the parotid gland. Rapidly growing. it metastasizes early to regional nodes and also by blood spread to the lungs, with a high mortality. all 4 cases presented here, having died within 2 yr of presentation. Histologically the lesion resembles the lymphoepithelioma or anaplastic carcinoma of the nasopharynx which has a high incidence in a closely related racial group. the southern Chinese. Differentiation from the benign epithelial lesion and from the salivary glands of Miculicz disease or Sjogren's syndrome is important. Difficulty may also be encountered in differentiation from a malignant histiocytic lymphoma involving the parotid. As the tumour closely resembles the nasopharyngeal carcinoma in which elevated EB virus titres have been found: blood from 2 of the above patients was examined but in neither was significant elevation detected. B I ~ N T I u E , DA\ID
HISTOLOGICAL CHANGES IN THE SKIN OCCURRING IN ANTARCTICA
BODEY,A. S. Purlinlog!. Department, Mercy Maternifj.Hospiial. East Melhourne Studies in human acclimatization to cold have covered a wide range of generalized effects. Skin studies have included changes in vascular responses. and two-point discrimination. Hitherto there have not been any
ROYAL COLLEGE OF PATHOLOGISTS OF AUSTRALIA
Pathology (1978), 10, April
communicated with bronchi proximally and with alveoli distally suggesting bronchiolectasis. However, there was also proliferation of bronchiolar structures, shown by their increase in number and by papillary overgrowth of the lining epithelium. Bronchiolar proliferation is also a feature of adenomatoid malformation. The 2 terms therefore, may possibly apply to different degrees of the same anomaly, a severe one producing stillbirth or neonatal death, and a milder one allowing survival long enough for successful surgical resection. One third of the children were full-term neonates. one third were aged 1 to 12 mth, and one third I to 10 yr. Fifteen of the specimens were surgical and 4 were necropsies. Half also had emphysema in the affected lobe, and 4 had associated extra lobar sequestration. None was associated with cysts in other organs. Radiologically and macroscopically. the overdistended lobe sometimes mimicked congenital lobar emphysema. All cases with more than focal chronic inflammation were omitted, in order to exclude post inflammatory pneumatoceles. Intrapulmonary bronchogenic cysts and intrapulmonary sequestrations differed in being usually single, often having cartilage and inflammatory fibrosis in their walls, and not having alveoli budding off the cyst. REACTION AGAINST ACTINICALLY-DAMAGED ELASTIN AS A BASIS OF TEMPORAL ARTERlTlS AND INTERNAL VASCULAR DISEASE
O'BRIEK. JOHN P. Medical Centre, Randwick. New Snutli Wales Evidence will be presented indicating the 'age change' and arteritis of the temporal artery are due to actinic damage. I t follows that the internal manifestations of the temporal arteritis/polymyalgia rheumatica syndrome, including its internal vascular complications. might likewise be due. albeit indirectly, to the same actinic cause. A PROPOSED CLASSIFICATION OF BENIGN TUMOURS OF ADIPOSE TISSUE ALLEN.P. W. Insriiuie o / Medicul & Veterinary Science Brunch Luhoraiory, Mount Gambier,
south Ausrruliu Benign fatty tumours fall into one of 5 groups; pure lipomas. benign mixed mesenchymal tumours of adipose tissue, hibernomas, lipoblastomas. and lipomatoses. Pure lipomas can be subdivided into solitary and multiple subcutaneous lipomas, and lipomas of other sites. Benign mixed mesenchymal tumours of adipose tissue can be subdivided into subcutaneous angiolipomas, including solitary. multiple. and multiple familial subcutaneous angiolipomas; subcutaneous fibrolipomas; subcutaneous myxolipomas: subcutaneous chondrolipomas; subcutaneous osteolipomas; mixtures of the preceding types: subcutaneous atypical fibrolipomas; subcutaneous spindle cell lipomas; intramuscular angiolipomas (haemangiomas of skeletal muscle); renal angiomyolipomas; and adrenal and presacral myelolipomas. It is suggested that the subcutaneous tissue is a topographic region in its own right, and that subcutaneous tumours should be considered separately from tumours of the deeper soft tissue. 'THE ESKIMOMA'-AN
UNUSUAL MALIGNANT SALIVARY GLAND TUMOUR
W. Parholog), Departnient. Royal Women'.e Hospital, Brishane Four cases of an unusual salivary gland tumour presented at the Health Science Centre, Winnipeg, Canada during a 5-yr period. from 1971 to 1976. This distinctive tumour was first described in 1963 when 9 cases were identified; 7 further cases were presented from Alaska in 1972. So far. the tumour appears to be confined to the Eskimo and to only involve the parotid gland. Rapidly growing. it metastasizes early to regional nodes and also by blood spread to the lungs, with a high mortality. all 4 cases presented here, having died within 2 yr of presentation. Histologically the lesion resembles the lymphoepithelioma or anaplastic carcinoma of the nasopharynx which has a high incidence in a closely related racial group. the southern Chinese. Differentiation from the benign epithelial lesion and from the salivary glands of Miculicz disease or Sjogren's syndrome is important. Difficulty may also be encountered in differentiation from a malignant histiocytic lymphoma involving the parotid. As the tumour closely resembles the nasopharyngeal carcinoma in which elevated EB virus titres have been found: blood from 2 of the above patients was examined but in neither was significant elevation detected. B I ~ N T I u E , DA\ID
HISTOLOGICAL CHANGES IN THE SKIN OCCURRING IN ANTARCTICA
BODEY,A. S. Purlinlog!. Department, Mercy Maternifj.Hospiial. East Melhourne Studies in human acclimatization to cold have covered a wide range of generalized effects. Skin studies have included changes in vascular responses. and two-point discrimination. Hitherto there have not been any