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Abstracts selected from annals of surgical oncology
European Journal of Surgical Oncology 1996; 22:308-309
Abstracts selected from
Annals of Surgical Oncology
Local Recurrence and Survival in Soft-Tissue Sarcomas Constantine P. Karakousis, MD, Phi), C. Proimakis, MD, Uma Rao, MD, Augustine E Velez, MD, and Deborah L. Driscoll, BA Background: There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. Design: We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. Methods: We evaluated prognostic parameters (grade, tumor size, location) and the effect of treatment on survival. Results: Resection of all the gross tumor at first visit to our Institute for local recurrence was accomplished in 88 patients (95%). Of the 59 patients with extremity tumors, six (10%) required amputation. At a mean follow-up of 66 months, further local recurrence was noted at 27%. The estimated 5-year survival rate was 100% for patients with grade I tumors ( n = 16), 77% for grade II (n=31), and 45% for grade III tumors (n=46) (p = 0.0002). This value was 78% for tumors ~<5cm and 57% for those >5cm (p=0.03). Conclusions: Local recurrence is resectable and limb preservation is possible in the majority of patients. The overall 5-year survival rate was 65%. Survival after treatment of local recurrence is determined mainly by the grade and secondarily by the size of the tumor as for primary sarcomas. Key words: Sarcomas---Local recurrence---Prognosticparameters--Survival.
Received April 4, 1995; accepted July 5, 1995. From the Millard Fillmore Hopitals, State University of New York, and Roswell Park Cancer Institute, Buffalo, New York (C.P.K.), and Montefiore University Hospital, Pittsburgh, Pennsylvania (U.R.), USA. Address correspondence and reprint requests to Dr. C. Karakousis, SurgicalOntology, Millard Fillmore Hospitals, 3 Gates Circle, Buffalo, NY 14209, USA. Reproduced with permission from Ann Surg Onco11996; 3: 225-60.
0748-7983/96/030308+02 $12.00/0
© 1996W.B.SaundersCompanyLimited
Abstracts selected from
Annals of Surgical Oncology
Local Recurrence and Survival in Soft-Tissue Sarcomas Constantine P. Karakousis, MD, Phi), C. Proimakis, MD, Uma Rao, MD, Augustine E Velez, MD, and Deborah L. Driscoll, BA Background: There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. Design: We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. Methods: We evaluated prognostic parameters (grade, tumor size, location) and the effect of treatment on survival. Results: Resection of all the gross tumor at first visit to our Institute for local recurrence was accomplished in 88 patients (95%). Of the 59 patients with extremity tumors, six (10%) required amputation. At a mean follow-up of 66 months, further local recurrence was noted at 27%. The estimated 5-year survival rate was 100% for patients with grade I tumors ( n = 16), 77% for grade II (n=31), and 45% for grade III tumors (n=46) (p = 0.0002). This value was 78% for tumors ~<5cm and 57% for those >5cm (p=0.03). Conclusions: Local recurrence is resectable and limb preservation is possible in the majority of patients. The overall 5-year survival rate was 65%. Survival after treatment of local recurrence is determined mainly by the grade and secondarily by the size of the tumor as for primary sarcomas. Key words: Sarcomas---Local recurrence---Prognosticparameters--Survival.
Received April 4, 1995; accepted July 5, 1995. From the Millard Fillmore Hopitals, State University of New York, and Roswell Park Cancer Institute, Buffalo, New York (C.P.K.), and Montefiore University Hospital, Pittsburgh, Pennsylvania (U.R.), USA. Address correspondence and reprint requests to Dr. C. Karakousis, SurgicalOntology, Millard Fillmore Hospitals, 3 Gates Circle, Buffalo, NY 14209, USA. Reproduced with permission from Ann Surg Onco11996; 3: 225-60.
0748-7983/96/030308+02 $12.00/0
© 1996W.B.SaundersCompanyLimited