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Alkalosis in burns in children
81
ABSTRACTS Hyperglycemia was a common but transient finding. Severe hypoglycemia with convulsions followed discontinuation of infusion in one child. Osmolality varied more than in control term infants. Five infants developed moderate to severe metabolic acidosis, always associated with hyperglycemia and, in four, with hyperosmolality. The authors conclude that infusion hyperglycemia and metabolic derangements are more likely to occur in premature infants treated by hyperalimentation than in fullterm infants. Immature organ function and underdeveloped enzyme systems may be responsible.-William K. Sieber
INTEGUMENT AND CONNECTIVE TISSUE
not necessarily symmetrical. Tenderness may occur. Adolescence is normal and no treatment is indicated.-Edward 7. Berman Inflammatory Carcinoma of the Breast in a 12-Year-Old Girl. Franc0 M. Nichini, Leonard Goldman, Marc S. Lapayowker, Walter M. Levy, Willis Maier, and George P.
Rosemond.
(September),
Arch.
in Burns in Children. J. A. Black, F. Harris, E. A. Lenfon, 13. W. S. Miller, and V. J. Child. Brit. Med. J. 4:387-388 (November), 1971.
Premature Thelarche. diat. Clin. N. Amer. 1972.
Albert Aifchek. Pe19543-545 (August),
Breast buds may appear as early as the age of 8 yr with precocious puberty. In premature thelarche, the enlargement occurs from 18 mo of age to 4 yr old. Enlargement is usually bilateral, although
105:505-508
The authors believe this to be the youngest reported patient with inflammatory carcinoma of the breast. Incisional biopsy was followed by radiotherapy and surgical castration. The ovaries contained metastatic tumor and a cell-block study of peritoneal fluid showed atypical cells. Chemotherapy was added to the radiotherapy. The disease was uncontrolled at the time of the report, 5 mo following the original treatment. -Edward
Alkaiosis
Fourteen children with burns involving more than 10% of body surface were investigated from the point of view of the acid-base state by daily investigations. The pH, standard HC03, PCO2, and plasma sodium, potassium, and urea were measured daily. Control figures from the same age group were obtained by a single estimation of the blood of 94 children who were admitted for elective operations such as tonsillectomy and herniotomy. The mean pH and standard HCO, of the burn patients were considerably raised as compared with mean figures for the controls. The PC02 values were similar in both groups. The metabolic alkalosis persisted until the burns were almost healed. The cause of the metabolic aIkaIosis is considered to be stimulation of the adrenal cortex.+. C. Grant
Surg.
1972.
J. Berman
HEAD AND NECK
Hemangiomas of the Parotid Gland in Infancy: A Clinico-radiological Study of ten Cases. A. Pampaloni and G. F. Vichi. Riv. Chir. Pediat. 14:1-19. 1972.
Sialography was performed in five of ten infants aged from 1 to 7 mo who were affected with unilateral enlargement of the parotid gland that proved to be hemangiomas. Ductal branches were constantly displaced outward, downward, and posteriorly, giving a clear, typical picture. In one case, ductal displacement showed a “ball-inhand” picture, typical of mixed tumors. Nevertheless, sialography proved to be a valuable aid in differential diagnosis between hemangioma, Iymphangioma, recurrent siaIadenitis, and mixed tumors. Out of five untreated cases, three had spontaneous regression, and two are on follow-up. One case was treated with radiotherapy (@JCo, 750 R) and cured. In four cases parotidectomy was performed with residual partial facial palsy in three cases. Histopathologic differentiation between cavernous hemangioma and hemangioendothelioma is important because of a spontaneous
Therapeutic
of the Iesser possibility regression in the latter.
indications
are
discussed.
A
ABSTRACTS Hyperglycemia was a common but transient finding. Severe hypoglycemia with convulsions followed discontinuation of infusion in one child. Osmolality varied more than in control term infants. Five infants developed moderate to severe metabolic acidosis, always associated with hyperglycemia and, in four, with hyperosmolality. The authors conclude that infusion hyperglycemia and metabolic derangements are more likely to occur in premature infants treated by hyperalimentation than in fullterm infants. Immature organ function and underdeveloped enzyme systems may be responsible.-William K. Sieber
INTEGUMENT AND CONNECTIVE TISSUE
not necessarily symmetrical. Tenderness may occur. Adolescence is normal and no treatment is indicated.-Edward 7. Berman Inflammatory Carcinoma of the Breast in a 12-Year-Old Girl. Franc0 M. Nichini, Leonard Goldman, Marc S. Lapayowker, Walter M. Levy, Willis Maier, and George P.
Rosemond.
(September),
Arch.
in Burns in Children. J. A. Black, F. Harris, E. A. Lenfon, 13. W. S. Miller, and V. J. Child. Brit. Med. J. 4:387-388 (November), 1971.
Premature Thelarche. diat. Clin. N. Amer. 1972.
Albert Aifchek. Pe19543-545 (August),
Breast buds may appear as early as the age of 8 yr with precocious puberty. In premature thelarche, the enlargement occurs from 18 mo of age to 4 yr old. Enlargement is usually bilateral, although
105:505-508
The authors believe this to be the youngest reported patient with inflammatory carcinoma of the breast. Incisional biopsy was followed by radiotherapy and surgical castration. The ovaries contained metastatic tumor and a cell-block study of peritoneal fluid showed atypical cells. Chemotherapy was added to the radiotherapy. The disease was uncontrolled at the time of the report, 5 mo following the original treatment. -Edward
Alkaiosis
Fourteen children with burns involving more than 10% of body surface were investigated from the point of view of the acid-base state by daily investigations. The pH, standard HC03, PCO2, and plasma sodium, potassium, and urea were measured daily. Control figures from the same age group were obtained by a single estimation of the blood of 94 children who were admitted for elective operations such as tonsillectomy and herniotomy. The mean pH and standard HCO, of the burn patients were considerably raised as compared with mean figures for the controls. The PC02 values were similar in both groups. The metabolic alkalosis persisted until the burns were almost healed. The cause of the metabolic aIkaIosis is considered to be stimulation of the adrenal cortex.+. C. Grant
Surg.
1972.
J. Berman
HEAD AND NECK
Hemangiomas of the Parotid Gland in Infancy: A Clinico-radiological Study of ten Cases. A. Pampaloni and G. F. Vichi. Riv. Chir. Pediat. 14:1-19. 1972.
Sialography was performed in five of ten infants aged from 1 to 7 mo who were affected with unilateral enlargement of the parotid gland that proved to be hemangiomas. Ductal branches were constantly displaced outward, downward, and posteriorly, giving a clear, typical picture. In one case, ductal displacement showed a “ball-inhand” picture, typical of mixed tumors. Nevertheless, sialography proved to be a valuable aid in differential diagnosis between hemangioma, Iymphangioma, recurrent siaIadenitis, and mixed tumors. Out of five untreated cases, three had spontaneous regression, and two are on follow-up. One case was treated with radiotherapy (@JCo, 750 R) and cured. In four cases parotidectomy was performed with residual partial facial palsy in three cases. Histopathologic differentiation between cavernous hemangioma and hemangioendothelioma is important because of a spontaneous
Therapeutic
of the Iesser possibility regression in the latter.
indications
are
discussed.
A