The second annual symposium sponsored by the Parkinson’s Disease Information and Research Center, the National Institutes of Health and the Parkinson’s Disease Foundation will be held on the 29th and 30th of November, 1965 at the College of Physicians and Surgeons, Columbia University, New York. A tentative program has been organized as follows : 1st Session:
THE BIOCHEMICAL FUNCTION
AND MORPHOLOGICAL
BASIS OF CHOLINERGTC
D. NACHMANSOHN(Chairman) : The Biochemical Busis of Cholinergic Drug Effects F. SJ~R~TRAND:The Structures of the Cell&r Membranes and Cell Membrane Contacts in the Nervous System W. RKER: The Motor Nerve Terminal as a Pharmacologic Substrate M. BRZIN, V. TENNYSON, P. DUFFY: Combined Cytochemical-Electron I.ocalization of the Cholinesterases in the Nervous System
Microscopic
2nd Session: THE BIOCHEMICAL
BASIS OF CENTRAL ADRENERGIC
S. UDENFRIEND (Chairman): Catecholamines in Brain
FUNCTION
General Remarks on the Biosynthesis and Metabolism of
A. CARELYON:Morphologic and Dynamic Aspects of Dopamine in the Central Nervous System 0. HORNYKIEWICZ: Metabolism of Brain Dopamine in Human Parkinsonism: Neurochemical and Clinical Aspects T. SOURKES:Amines of the Striatum: Relation to Experimental Tremor in the Monkey
3rd Session: MICROCHEMICAL
STUDIES OF BASAL GANGLIA
METABOLISM
B. BRODE (Chairman) H. HVDEN: Production of RNA in Neurones and Glia in Parkinson’s Disease indicating Genie Stimulation R. PAVLIN: The Activities of the Cholinesterases in the Reticular Formation Neurones investigated by Micromanometric Techniques
4th Session:
THE PHARMACOLOGY
OF ADRENERGIC
FUNCTION
B. BRODIE(Chairman) E. COSTAand N. H. NEFF: Isotopic and Non-Isotopic cholamine
Measurements
of the Rate of Cate-
Biosynthesis
A. SJOERDSMA : Chemical Manipulation
of Catecholamine
Enzymes
5th Session: Round table conference
PROMISING
APPROACHES
TO NEUROLOGY
FROM BASIC SCIENCES
S. KETY (Chairman) Participants:
B. BRODIE, H. HYDEN, E. KABAT, D. NACHMANSOHN,W. J. NAUTA, D. PURPURA, F. SJ~RSTRAND,S. UDENFRIEND,A. WOLF
The meeting is open to all those interested in the neurological sciences. Information on the program and advanced registration cards (at no cost) may be obtained from: MELVIND. YAHR, M.D.
(program co-director) 7 10 West 168th Street, New York, New York 10032