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CME examination for volume 13
IOURNAL O[ t h e AcaDemy OF
AmemcaN "~
1938
DerMaTOLOGY
00
II
I
I
II
I
I
I
In the June and D e c e m b e r issues each year, CME questions based on articles in the preceding volume of the JOURNAL appear. Two hours of Category 1 C M E credit can be earned b y reading the text material, reporting the answers on the perforated answer sheet, and following instructions for Category 1 CME credit.--Editor
CME examination for volume 13" Identification No. 886-306
Instructions for Category 1 CME credit and answers to this examination appear in the front advertising section. See last page of Contents for page number.
Directions for questions 1.13: Give single best response. 1. What proportion of patients with AIDS (acquired immunodeficieney syndrome) or pre-AIDS have been found to have circulating antibodies specific for human T-cell lymphotropic virus (HTLV-III)? a. Less than I% b. 15% c. 40% d. 65% e. Over 85% 2. What proportion of healthy heterosexuals have been found to have circulating antibodies specific for HTLV-III? a. Less than 1% b. 15% c. 40% d. 65% e. Over 85% 3. Large, pigmented, round, thick-walled bodies with septation in two planes (muriform cells) are characteristic of a, chromoblastomycosis b . phaeohyphomycosis c. mycetoma d. endothrix tinea capitis e. ectothrix tinea capitis 4. Foci of subcutaneous fat necrosis associated with pancreatic disease preferentially localize to the a. abdomen b. groin c. lower aspects of the legs d. feet e. a r m s
*Includes entire volume with the exception of CME articles.
30A
5. Caripito itch is caused by contact with a certain genus of a. fleas b. mites c. flies d. moths e. parasitic worms 6. Which one of the following is an example ofepidermolytic epidermolysis bullosa, as contrasted with junctional or dermolytic epidermolysis bullosa? a. Dowling-Meara syndrome b. Herlitz syndrome c. Cockayne-Touraine syndrome d. Pasini syndrome e. Hallopeau-Siemens syndrome 7. Current evidence indicates that all of the following are significant prognostic factors in melanomas,
except a. anatomic location b. tumor type c. presence of microscopic satellites d. mitotic rate e. type of initial biopsy 8. Current evidence supports all of the following as possible causes of hair regrowth mediated by minoxidil in areas of male pattern baldness, except (a) (an) a. increased cutaneous blood flow b. mitogenic effect of the drug on hair matrix cells c. morphologic effect of the drug on hair matrix cells d. prevention or retardation of the progressive senescence of hair matrix cells e. antiandrogenic effect 9. Approximately what proportion of cases of lymphomatoid papulosis develop lymphoreticular malignancy? a. 0% b. 1% c. 15% d. 50% e. 80%
3:IA
Journal of the American Academy of Dermatology
CME examination for volume 13
10. Microscopic examination of biopsy sections from affected areas of male pattern baldness reveals all of the following except a. progressive shrinking of the scalp hair follicles b. shortening of the hair growth cycle c. dense collections of lymphoeytes around the base of the hair follicle d. cessation of all hair production e. disappearance of the entire pilosebaceous apparatus 11. Reported characteristics ofmalignantpyodermainelude all of the following, except (a) a. occurrence chiefly in the elderly b. involvement of the head and neck c. predilection for the periauricular region d. progressive, chronic course e. response to isotretinoin and sulfapyridine 12. The "hippocratic wreath" is found a. along the anterior aspect of the scalp b. on the ment.al (chin) region extending from one preauricular area to the other c. on the posterior aspect of the scalp just above the neck d. on the posterior cervical (neck) region, extending from one anterior triangle region to the other e. on the nasal bridge extending from one malar eminence to the other 13. A deoxyribonucleic acid (DNA) molecule containing a long wavelength ultraviolet (A) radiationinduced psoralen (i.e., PUVA) cross-link probably appears as a a. smooth double helix showing little or no distortion b. double helix with one smooth strand and one markedly distorted strand c. double helix with both strands markedly distorted d. section of Z DNA in its natural configuration e. section of Z DNA in a markedly distorted configuration
Directions for questions 14-18: For each numbered item choose the appropriate lettered item. a. Benign lichenoid keratosis b. Lichenoid actinic keratosis c. Both d. Neither 14. Apparently related to, or a variant of, a reticulated seborrheic keratosis 15. Apparently related to, or a variant of, a senile lentigo I6. Nuclear atypia is present
17. Lichenoid inflammation more or less resembling lichen planus is present 18. Tends to occur in sun-exposed areas a. Adenine arabinoside (Vira-A) b. Acyclovir (Zovirax) c. Both d. Neither
Directions for questions 19-22: For each numbered item choose the appropriate lettered item. 19. Favorably influences the course of herpes zoster in immunocompromised patients 20. Accelerates cutaneous healing of herpes lesions 21. Reduces visceral complications when given for early localized herpes 22. Use of intravenous therapy requires hospitalization a. Streptococcal impetigo b. Staphylococcal impetigo c. Both d. Neither
Directions for questions 23-26: For each numbered item choose the appropriate lettered item. 23. Typically a bullous disorder 24. Skin disease caused by a toxin 25. Typical early lesion contaminated with the alternate organism 26. Common type of impetigo contagiosa worldwide
Directions for questions 27-31: lndicate correct answers. All, some, or none of the choices may be correct. 27. Pyoderrna gangrenosum has been reported to occur in association with a. rheumatoid arthritis b. multiple myeloma c. myelofibrosis d. chronic active hepatitis e. chronic persistent hepatitis 28. Risk factors for streptococcal pyoderma include a a. living in a family or in a closed or institutional population b. age 2 to 5 years c. warm, moist climate d. poor hygiene e. minor trauma to the skin 29. The yellow nail syndrome has been found in association with a. bronchiectasis b. sinusitis c. bronchitis
34A
CME examination for volume 13
d. chronic respiratory infections e, AIDS (acquired immunodeficiency syndrome) with Pneumocystis carinii pneumonia 30. Known effects of colchicine include a. prevention of formation of antigen-antibody complexes b. prevention of deposition of antigen-antibody complexes on vascular basement membranes c. inhibition of chemotaxis of neutrophils
Journal of the American Academy of Dermatology
d. inhibition of formation of lysosomes e. destabilization of lysosomal membranes 31, The clinical spectrum of psoriasis vulgaris may include a. pathologic changes in the liver b. increased risk of thromboembolic disease c. malabsorptive enteropathy d, type IV hyperlipoproteinemia e. hypertriglyceridemia
AmemcaN "~
1938
DerMaTOLOGY
00
II
I
I
II
I
I
I
In the June and D e c e m b e r issues each year, CME questions based on articles in the preceding volume of the JOURNAL appear. Two hours of Category 1 C M E credit can be earned b y reading the text material, reporting the answers on the perforated answer sheet, and following instructions for Category 1 CME credit.--Editor
CME examination for volume 13" Identification No. 886-306
Instructions for Category 1 CME credit and answers to this examination appear in the front advertising section. See last page of Contents for page number.
Directions for questions 1.13: Give single best response. 1. What proportion of patients with AIDS (acquired immunodeficieney syndrome) or pre-AIDS have been found to have circulating antibodies specific for human T-cell lymphotropic virus (HTLV-III)? a. Less than I% b. 15% c. 40% d. 65% e. Over 85% 2. What proportion of healthy heterosexuals have been found to have circulating antibodies specific for HTLV-III? a. Less than 1% b. 15% c. 40% d. 65% e. Over 85% 3. Large, pigmented, round, thick-walled bodies with septation in two planes (muriform cells) are characteristic of a, chromoblastomycosis b . phaeohyphomycosis c. mycetoma d. endothrix tinea capitis e. ectothrix tinea capitis 4. Foci of subcutaneous fat necrosis associated with pancreatic disease preferentially localize to the a. abdomen b. groin c. lower aspects of the legs d. feet e. a r m s
*Includes entire volume with the exception of CME articles.
30A
5. Caripito itch is caused by contact with a certain genus of a. fleas b. mites c. flies d. moths e. parasitic worms 6. Which one of the following is an example ofepidermolytic epidermolysis bullosa, as contrasted with junctional or dermolytic epidermolysis bullosa? a. Dowling-Meara syndrome b. Herlitz syndrome c. Cockayne-Touraine syndrome d. Pasini syndrome e. Hallopeau-Siemens syndrome 7. Current evidence indicates that all of the following are significant prognostic factors in melanomas,
except a. anatomic location b. tumor type c. presence of microscopic satellites d. mitotic rate e. type of initial biopsy 8. Current evidence supports all of the following as possible causes of hair regrowth mediated by minoxidil in areas of male pattern baldness, except (a) (an) a. increased cutaneous blood flow b. mitogenic effect of the drug on hair matrix cells c. morphologic effect of the drug on hair matrix cells d. prevention or retardation of the progressive senescence of hair matrix cells e. antiandrogenic effect 9. Approximately what proportion of cases of lymphomatoid papulosis develop lymphoreticular malignancy? a. 0% b. 1% c. 15% d. 50% e. 80%
3:IA
Journal of the American Academy of Dermatology
CME examination for volume 13
10. Microscopic examination of biopsy sections from affected areas of male pattern baldness reveals all of the following except a. progressive shrinking of the scalp hair follicles b. shortening of the hair growth cycle c. dense collections of lymphoeytes around the base of the hair follicle d. cessation of all hair production e. disappearance of the entire pilosebaceous apparatus 11. Reported characteristics ofmalignantpyodermainelude all of the following, except (a) a. occurrence chiefly in the elderly b. involvement of the head and neck c. predilection for the periauricular region d. progressive, chronic course e. response to isotretinoin and sulfapyridine 12. The "hippocratic wreath" is found a. along the anterior aspect of the scalp b. on the ment.al (chin) region extending from one preauricular area to the other c. on the posterior aspect of the scalp just above the neck d. on the posterior cervical (neck) region, extending from one anterior triangle region to the other e. on the nasal bridge extending from one malar eminence to the other 13. A deoxyribonucleic acid (DNA) molecule containing a long wavelength ultraviolet (A) radiationinduced psoralen (i.e., PUVA) cross-link probably appears as a a. smooth double helix showing little or no distortion b. double helix with one smooth strand and one markedly distorted strand c. double helix with both strands markedly distorted d. section of Z DNA in its natural configuration e. section of Z DNA in a markedly distorted configuration
Directions for questions 14-18: For each numbered item choose the appropriate lettered item. a. Benign lichenoid keratosis b. Lichenoid actinic keratosis c. Both d. Neither 14. Apparently related to, or a variant of, a reticulated seborrheic keratosis 15. Apparently related to, or a variant of, a senile lentigo I6. Nuclear atypia is present
17. Lichenoid inflammation more or less resembling lichen planus is present 18. Tends to occur in sun-exposed areas a. Adenine arabinoside (Vira-A) b. Acyclovir (Zovirax) c. Both d. Neither
Directions for questions 19-22: For each numbered item choose the appropriate lettered item. 19. Favorably influences the course of herpes zoster in immunocompromised patients 20. Accelerates cutaneous healing of herpes lesions 21. Reduces visceral complications when given for early localized herpes 22. Use of intravenous therapy requires hospitalization a. Streptococcal impetigo b. Staphylococcal impetigo c. Both d. Neither
Directions for questions 23-26: For each numbered item choose the appropriate lettered item. 23. Typically a bullous disorder 24. Skin disease caused by a toxin 25. Typical early lesion contaminated with the alternate organism 26. Common type of impetigo contagiosa worldwide
Directions for questions 27-31: lndicate correct answers. All, some, or none of the choices may be correct. 27. Pyoderrna gangrenosum has been reported to occur in association with a. rheumatoid arthritis b. multiple myeloma c. myelofibrosis d. chronic active hepatitis e. chronic persistent hepatitis 28. Risk factors for streptococcal pyoderma include a a. living in a family or in a closed or institutional population b. age 2 to 5 years c. warm, moist climate d. poor hygiene e. minor trauma to the skin 29. The yellow nail syndrome has been found in association with a. bronchiectasis b. sinusitis c. bronchitis
34A
CME examination for volume 13
d. chronic respiratory infections e, AIDS (acquired immunodeficiency syndrome) with Pneumocystis carinii pneumonia 30. Known effects of colchicine include a. prevention of formation of antigen-antibody complexes b. prevention of deposition of antigen-antibody complexes on vascular basement membranes c. inhibition of chemotaxis of neutrophils
Journal of the American Academy of Dermatology
d. inhibition of formation of lysosomes e. destabilization of lysosomal membranes 31, The clinical spectrum of psoriasis vulgaris may include a. pathologic changes in the liver b. increased risk of thromboembolic disease c. malabsorptive enteropathy d, type IV hyperlipoproteinemia e. hypertriglyceridemia