Contributors to volume 202

Contributors to V o l u m e 202 Article numbersare in parenthesesfollowingthe names Affiliationslisted are current.

DAVID A. AGARD (28), Department of

of

contributors.

Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, California 94143 FRED E. COHEN (13), Departments of Pharmaceutical Chemistry and Medicine, University of California at San Francisco, San Francisco, California 94143 MALCOLM E. DAVIS (22), Department of Chemistry, University of Houston, Houston, Texas 77204 JACOB DE VLIEG (14), European Molecular Biology Laboratory, 6900 Heidelberg, Federal Republic of Germany

Biochem&try and Biophysics and The Howard Hughes Medical Institute, University o f California at San Francisco, San Francisco, California 94143 N. M. ALLEWELL (1), Department of Molecular Biology and Biochemistry, and Program in Molecular Biophysics, Wesleyan University, Middletown, Connecticut 06457 STUART A. ALLISON (22), Department of Chemistry, Georgia State University, Atlanta, Georgia 30303 FAHAD AL-OBEIDI (19), Chemistry Department, University of Houston, Houston, Texas 77204 GREGORIO AEVARO (27), Department of Chemical Engineering and Center for Biotechnology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261

JON ELLMAN (15), Department of Chemis-

try, University of California at Berkeley, Berkeley, California 94720 ALAN R. FERSHT (6), MRC Unit for Protein Function and Design, Cambridge IRC for Protein Engineering, Department of Chemistry, University of Cambridge, Cambridge, CB2 IEW, England

SPENCER ANTHONY-CAHILL (15), E. 1. Du-

pont de Nemours, CR & D, Wilmington, Delaware 19880 ROGER BONE (28), Department of Biophysical Chemistry, Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey 07065 WILLIAM M. BRYAN (20), Department of Peptidomimetic Research, SmithKline Beecham, King o f Prussia, Pennsylvania 19406 STEPHEN H. BRYANT (2), Biometrics Laboratory, Wadsworth Center for Laboratories and Research, Biomedical Science Department, New York State Department of Public Health, Albany, New York 12201 XIAOWU CHEN (7), Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802 BRUCE I. COHEN (13), Section on Medical Information Service, Department of

BRYAN E. FINN (7), Department of Physical

Chemistry H, Chemical Center, University of Lund, S-221 O0 Lund, Sweden LASZLO GRAF (29), Biochemistry Department, L. Eotvos University, 1088 Budapest, Hungary JONATHAN GREER (12), Computer Assisted Molecular Design Group, Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064 CORWIN HANSCH (24), Department of Chemistry, Pomona College, Claremont, California 91711 LIZBETH HEDSTROM (29), Department of Biochemistry, Hormone Research Institute, University of California at San Francisco, San Francisco, California 94143 W. J. HENNEN (26), Parish Chemical Co., Orem, Utah 84057 ix

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CONTRIBUTORS TO VOLUME

202

L. HOWARD HOLLEY (10), Department

RAUA L. P. LINDBERG (33), Department of

of Chemistry, Harvard University, Cambridge, Massachusetts 02138

Pharmacology Biocenter, University of Basel, Basel, Switzerland

ROBERT E. HUMPHREYS (ll), Departments

DANIEL D. LOEB (17), Department of Mi-

of Pharmacology, Biostatistics, and Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655 CLYDE A. HUTCnISON III (17), Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 PATRICIA A. JENNINGS (7), Department of Molecular Biology, Research Institute of Scripps Clinic, La Jolla, California 92037 MARTIN KARPLUS (9, 10), Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138 KASPER KIRSCHNER (4), Abteilung Biophysikalische Chemie, Biozentrum der Universitiit, CH-4056 Basel, Switzerland TERl E. KLEIN (24), Computer Graphic Laboratory, School of Pharmacy, University of California at San Francisco, San Francisco, California 94143 LAWRENCE C. KUO (31), Division of Biological Chemistry, Merck, Sharp and Dohme Research Laboratories, West Point, Pennsylvania 19486 CHARLES E. LAWRENCE (2), Biometrics Laboratory, Wadsworth Center for Laboratories and Research, Biomedical Science Department, New York State Department of Public Health, Albany, New York 12201 ALBERT J. LEO (25), Medicinal Chemistry Project, Seaver Chemistry Laboratory, Pomona College, Claremont, California 91711 ROBERT A. LEW (11), Departments of Pharmacology, Biostatistics, and Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655 RICHARD A. LEWIS (8), Biomolecular Modeling, Imperial Cancer Research Fund, Lincolns Inn Fields, London WC2A 3PX, England

crobiology, and Immunology, University of California at San Francisco, San Francisco, California 94143 SHAN L u (11), Departments of Pharmacol-

ogy, Biostatistics, and Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655 BROCK A. LUTY (22), Department of Chem-

istry, University of Houston, Houston, Texas 77204 ALEXANDER D. MACKERELL, JR. (21), De-

partment of Chemistry, Harvard University, Cambridge, Massachusetts 02138 JEEERY O. MADURA (22), Department of Chemistry, University of South Alabama, Mobile, Alabama 36688 ANDREAS MATOUSCHEK (6), MRC Unit for

Protein Function and Design, Cambridge 1RC for Protein Engineering, Departments of Chemistry, University of Cambridge, Cambridge, CB2 1EW, England MASAZUMI MATSUMURA (16), Department of Immunology, Research Institute of Scripps Clinic, La Jolla, California 92037 BRIAN W. MATTHEWS (16), Institute of Molecular Biology, Department of Physics and Howard Hughes Medical Institute, University of Oregon, Eugene, Oregon 97403 C. ROBERT MATTHEWS (7), Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802 J. ANDREW MCCAMMON (22, 23), Department of Chemistry, University of Houston, Houston, Texas 77204 DAVID MENDEL (15), Department of Chemistry, University of California at Berkeley, Berkeley, California 94720 MASAHIKO NEGISHI (33), Pharmacogenetics Section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental

CONTRIBUTORS TO VOLUME

202

xi

Health Sciences, National Institute of Health, Research Triangle Park, North Carolina 27709

PETER G. SCHULTZ (15), Department of

THOMAS NIERMANN (4), Abteilung Bio-

G.-J. SHEN (26), Department of Chemistry,

physikalische Chemie, Biozentrura der Universitiit, CH-4056 Basel, Switzerland KEN NISHIKAWA (3), Protein Engineering Research Institute, Osaka 565, Japan TAMOTSU NOGUCHI (3), Protein Engineer-

ing Research Institute, Osaka 565, Japan CHRISTOPHER J. NOREN (15), New England

Chemistry, University of California at Berkeley, Berkeley, California 94720 Research Institute of Scripps Clinic, La Jolla, California 92037 BANCINYANE LYNN SIBANDA (5), Labora-

tory of Molecular Biology, Department of Crystallography, Birkbeck College, London WCIE 7HX, England JACQUELINE SINES (22), Biochemistry De-

partment, Baylor College of Medicine, Houston, Texas 77204

Biolabs, Beverly, Massachusetts 01915 H. OBEROI (1), Department of Molecular Biology and Biochemistry, and Program in Molecular Biophysics, Wesleyan University, Middletown, Connecticut 06457

PAUL E. SMITH (19), Chemistry Depart-

R. L. PEDERSON (26), Bend Research Inc.,

CARO-BETH STEWART (29), Department

Bend, Oregon 97701 B. MONTGOMERY PETTITT (19), Chemistry

Department, University Houston, Texas 77204

of Houston,

MARGARET A. PHILLIPS (29), Department of

Biochemistry, Hormone Research Institute, University of California at San Francisco, San Francisco, California 94143 SCOTT R. PRESNELL (13), Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, California 94143 VICTOR E. REYES (11), Departments of Pharmacology, Biostatistics, and Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655 ALAN J. RUSSELL (27), Department of Chemical Engineering and Center for BiDtechnology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 WILLIAM J. RUTTER (29), Department of Biochemistry, Hormone Research Institute, University of California at San Francisco, San Francisco, California 94143 SUSANNE M. SAALAU-BETHELL (7), Department of Genetics, Glaxo Group Research, Greenford, Middlesex UB6 0HE, England

ment, University of Houston, Houston, Texas 77204 of Biological Sciences, SUNY at Albany, Albany New York 12222 T. P. STRAATSMA (23), Department

of Chemistry, University of Houston, Houston, Texas 77204

NEENA L. SUMMERS (9), Monsanto Corpo-

rate Research, The Monsanto Company, Chesterfield, Missouri 63017 RONALD SWANSTROM (17), Department of

Biochemistry, Lineberger Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 JANET M. THORNTON (5), Biomedical Struc-

ture and Modelling Unit, Biochemistry and Molecular Biology Department, University College, London WCIE 7HX, England WILFRED F. VAN GUNSTEREN (14), Laboratory of Physical Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands MEE|NDA E. WALES (30), Department of Biochemistry and Biophysics, Texas A & M University, College Station, Texas 77843 Y.-F. WANG (26), School of Pharmacy,

Kaohsiung Medical College, Kaohsiung, Taiwan

xii

CONTRIBUTORS TO VOLUME 202

IRENE T. WEBER (32), Department of Phar-

JAMES R. WILD (30), Department of Bio-

macology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107

chemistry and Biophysics, Texas A & M University, College Station, Texas 77843

JAMES A. WELLS (18), Department of Pro-

C.-H. WONG (26), Department of Chemis-

tein Engineering, Genentech, Inc., South San Francisco, California 94080

try, Research Institute of Scripps Clinic, La Jolla, California 92037