Corrigendum to “Differential gene regulation of GHSR signaling pathway in the arcuate nucleus and NPY neurons by fasting, diet-induced obesity, and 17β-estradiol” [Mol. Cell. Endocrinol. 157 (2016) 679–691]

Molecular and Cellular Endocrinology 428 (2016) 171e173

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Corrigendum

Corrigendum to “Differential gene regulation of GHSR signaling pathway in the arcuate nucleus and NPY neurons by fasting, dietinduced obesity, and 17b-estradiol” [Mol. Cell. Endocrinol. 157 (2016) 679e691] Ali Yasrebi a, Anna Hsieh a, Kyle J. Mamounis a, b, Elizabeth A. Krumm a, c, Jennifer A. Yang a, c, Jason Magby a, Pu Hu a, Troy A. Roepke a, b, c, d, * a

Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA Nutritional Sciences Graduate Program, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA c Graduate Program in Endocrinology and Animal Biosciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA d New Jersey Institute for Food, Nutrition, and Health, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA b

The authors regret that an incorrect version of Fig. 4 was submitted. Fig. 4E and F were accidently switched in the final submission. The text is correct. Table 2: a summary of results was also mislabelled. Both Fig. 4 and Table 2 have been corrected and are submitted below. The authors would like to apologise for any inconvenience caused.

DOI of original article: http://dx.doi.org/10.1016/j.mce.2015.11.007. * Corresponding author. Department of Animal Sciences, 84 Lipman Drive, Bartlett Hall, New Brunswick, NJ, 08901, USA. E-mail address: [email protected] (T.A. Roepke). http://dx.doi.org/10.1016/j.mce.2016.04.017 0303-7207/© 2016 Elsevier Ireland Ltd. All rights reserved.

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A. Yasrebi et al. / Molecular and Cellular Endocrinology 428 (2016) 171e173

Fig. 4. EB differentially regulated expression of GHSR pathway genes between the ARC and NPY neurons in ovx females. In fed females, (A) EB increased Agrp, Ghsr, Cpt1c, and Foxo1 expression in the ARC and (B) increased Agrp expression and decreased Foxo1 expression in NPY pools. In fasted females, (C) EB increased Ghsr, Cpt1c, and Foxo1 expression in the ARC and (D) increased Foxo1 expression in NPY pools. (E) In oil-treated ARC, fasting increased Npy, Agrp, and Ghsr expression. (F) In EB-treated ARC, fasting increased Npy and Agrp expression. Data are represented as mean ± SEM normalized to oil (AeD) or fed (EeF). Gene expression data were analyzed by a two-way ANOVA with post hoc Bonferroni multiple comparison test (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001). Numbers in parentheses represent sample size.

A. Yasrebi et al. / Molecular and Cellular Endocrinology 428 (2016) 171e173

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Table 2 A summary of results. Male

Female Fed vs. Fasted

Gene name Npy Agrp Ghsr Ucp2

Fast Arc NPY Arc NPY Arc NPY Arc NPY

Arc NPY Arc NPY Arc NPY

Oil fast

EB fast

Arc

Arc

Arc

Arc

Fed EB

Fast EB

NPY Fig. 2

Diet

EB

Diet
EB * NPY

* Arc * NPY

NPY

Arc

* Arc * NPY * Arc

* NPY * NPY

* Arc * Arc * NPY

Arc NPY

Cpt1c Foxo1

HFD

ND vs. HFD

Fig. 3

Fig. 4E

Fig. 4

NPY Fig. 4B

NPY Fig. 4D

* NPY

Fig. 6E and F

For male fasted and HFD and female fasted experiments: denotes an increase in expression; denotes a decrease in expression. For female ND vs. HFD: * denotes significant effect of diet, EB, or interaction. ARC ¼ arcuate nucleus. NPY ¼ pools of NPY neurons. Treatment headings are in comparison to Fed and ND for males. For female fed vs. fasted, Fast is in comparison to fed within steroid treatment in the ARC and EB is in comparison to oil within fed or fasted state in NPY pools.