This self-assessment section is brought to you in association with Elsevier’s ExamPrep (www.elsevierexamprep.co.uk/individual). Every month we will feature MRCP (UK) style questions based on the chapter’s topic. Answers are provided online only at www.medicinejournal.co.uk/content/cpd
Questions
Select the ONE single best answer from the five alternatives:
Question 1 An 86-year-old woman presented with a 3-day history of diarrhoea and vomiting. She had hypertension that was well controlled by ramipril 5 mg daily and amlodipine 10 mg daily. On examination, when supine, her blood pressure was 93/ 45 mmHg but her jugular venous pressure was not visible. Her oxygen saturation was normal, breathing 2 litres of oxygen. Urinalysis was negative for blood and protein.
sodium potassium urea creatinine
haemolytic uraemic syndrome lupus nephritis
D
post-infectious glomerulonephritis
E
thrombotic thrombocytopenic purpura
Question 3 A 79-year-old woman had a 1-week history of malaise, abdominal pain and nausea. She had a history of hypertension, which was controlled by amlodipine 10 mg daily. Two weeks before admission, her blood pressure had been normal. On examination, her pulse was 102 beats per minute and her blood pressure was 110/50 mmHg lying. Urinalysis showed blood 2D and protein 3D.
What is the most likely cause of her renal failure? A
acute papillary necrosis
B
acute tubular necrosis
C
acute tubulointerstitial nephritis
D
cast nephropathy
E
rhabdomyolysis
Question 2 A 35-year-old man was admitted with a 2-day history of bloody diarrhoea. He had visited a fairground at the weekend with his friends and had eaten a beef burger. On examination, his temperature was 38 C and his blood pressure was 180/104 mmHg.
What is the most likely underlying diagnosis?
Investigations: haemoglobin white cell count platelet count blood film serum sodium serum potassium serum urea serum creatinine serum lactate dehydrogenase serum C-reactive protein