- Email: [email protected]
Development and Recognition of the Transformed Cell
J. steroid Biochem. Vol. 33, No. 1, pp. 147-148, 1989
MaxwellPergamon Macmillan pk. Printed in Great Britain
BOOK REVIEWS
Structwe and Function of Major and Minor SmaB Nuclear the very extensive area of the action of hormones in most Ribonucleoproteio Particles. Edited by M. L. BIRNSTIEL. endocrine cancers and includes the following main sections: Published 1988 by Springer-Verlag, Berlin. No. of pages: -Hormone receptors 216. Price: DM 198 (hard cover). ISBN: 3-540-18410-4. -Antibodies to hormone receptors -Hormonal regulation of gene expression In the last decade there was a big advance in the study of -Control of cell proliferation small nuclear ribonucleoproteins and the process of the -Growth factors mechanism of catalysis in RNA processing. This book -Biology of tumor spread contains up-to-date information on these problems and -Tumor markers includes the following main chapters: -Enzyme inhibitors -Small nuclear RNAs: RNA sequences, structure, and -Antihormones modifications -Breast cancer -The genes and transcription of the major small nuclear -Endometrial cancer RNAs -Prostate cancer -snRNP proteins -Lung, kidney and gastrointestinal cancer. -UsnRNP assembly and transport This book is very useful for people working in oncology, -Functions of the abundant U-snRNPs general clinicians, and advanced students in physiology, -Structure and function of minor snRNPs biochemistry and molecular biology. -Ribonuclease-P as a snRNP --Genetic
analysis of yeast snRNAs.
This book is very useful for researchers working in molecular biology, biochemistry, biophysics and biology.
In EnxymoIogy. Editors-in-Chief: SIDNEY P. and NATHAN0. KAPLAN Vol. 147: Pep& Growth Faetora-Part B. Edited by DAVID BARNWand D~vm A. SUUMSKU.Published 1987 by Academic Press, San Diego. No. of pages: 488. Price as at December 1988: $65.00. ISBN: o-12-182047-5.
Development
nod ReeognItIoo of the Tras&xmed CeB. Edited by MARK I. GREENEand Toarrrvu~~ HAMAOKA. Published 1987 by Plenum Press, New York. No. of pages: 460. Price as at March 1988: S65.00. ISBN: O-306-42636-6.
M&ads
CCJLOWICK
In the last years one of the most important impacts in biological. research has been the exploration of the mechanisms through which normal cells are transformed into malignant cells. This book contains upto-date information on this problem and the main topics concerned are as follows:
In recent years one of the biggest discoveries in biology was the presence of growth factors which are involved in many organs of different animal species, and one of the most important functions of this factor concerns cell proliferation. This book gives a general outline of recent information concerning different growth factors which include:
-Cytogenetics of neoplasia -The structure and function of the normal c-myc gene and its alteration in malignant cells -Protooncogene expression in lymphoid cells: implications for the regulation of normal cellular growth -0ncogene products as receptors -Monoclonal antibodies reactive with the neu oncogene -Platelet-derived growth factor product inhibit the neoplastic properties of neu-trans-Angiogenesis, endothelial and fibroblast growth factors formed cells -Nerve and glial growth factors -Relationship of the c-fm protooncogene product to the -Transferrin, erythropoietin, and related factors CSF-1 receptor -Techniques for the study of growth factor activity: genetic -Two &l-related protooncogenes encoding growth approaches and biological effects. factor receptors -The receptor for epidermal growth factor In each section is treated the chemical composition of -The role of the ubl gene in transformation growth factors, receptors, biological function and interac-Comparison of the structural and functional properties of tion with other growth factors in the different organelles of the viral and cellular WCgene products the cells. -Protein kinase C as the site of action of the phorbol ester This book is very useful for researchers in molecular tumor promoters endocrinology, biology, biochemistry, and physiology. -Involvement of human retrovirus in specific T-cell leukemia -Mechanisms of virus-induced alterations of expression of Class I genes and their role on tumorigenesis Hormones and Cancer, Volume 3. Series: Progress in Cancer Research and Therapy, Vol. 35. Edited by F. BREWANI, -Antigenic requirements for the recognition of Maloney murine leukemia virus-induced tumors by cytotoxic T ROGERJ. B. KING, MARC E. LIPPMANand JEAN-PIERRE lymphocytes RAYNAUD.Published 1988 by Raven Press, New York. No. of pages: 576. ISBN: O-88167-453-2. -SV40 tumor antigen: importance of cell surfact localixation in transformation and immunological control of neoplasia This book contains the Proceedings of the Third International Congress on Hormones and Cancer, held in Hamburg -Correlation of natural killer cell recognition with ras oncogene expression (Federal Republic of Germany) in September 1987. It covers 147
148
Book reviews
-A
regulatory role of natural killer cells (LGL) in T-cellmediated immune response -Immune regulation in neoplasia: dominance of suppressor systems -The generation and down-regulation of the immune response to progressive tumors -Origin and significance of transplantation antigens induced on cells transformed by UV radiation -Cellular and molecular mechanisms involved in tumor eradication in uiuo -Application of T-cell-T-cell interaction to enhanced tumor-specific immunity capable of eradicating tumor cells in vivo -Antigens expressed by melanoma and melanocytes: studies of the immunology, biology and genetics of melanoma -Malignant transformational changes of the sugar chains of glycoproteins and their clinical application -Ganglioside involvement in tumor cell-substratum interactions -Specific adoptive therapy of disseminated tumors: requirements for therapeutic efficacy and mechanisms by which T-cells mediate tumor eradication. This book would be useful for oncologists, clinicians, physiologists, biochemists, and researchers working in molecular biology. Pediatric Endocrinology-2nd Edition. Edited by R. COLLU, J. R. DUCHARME and H. J. GWDA. Comprehensive Endocrinology (Revised Series). Series editor: L. MARTINI. Published 1988 bv Raven Press. New York No. of oases: 704. Price as of December 1988: $177.50. ISBN: 0-8’8ik7477-X. This is an up-to-date book on most problems concerning pediatric endocrinology and contains major advances in pathophysiology, pharmacology, molecular biology and neuroregulatory mechanisms. The main topics covered are: -Neuroendocrine control of pituitary hormone secretion -Mechanisms of polypeptide hormone action: current concepts -Steroid hormone action --Ontogeny of pituitary hormone secretion -Abnormalities of growth --Insulin-like growth factors -Sexual differentiation -Molecular genetic approaches to testis differentiation -Normal puberty: clinical manifestations and their endocrine control -Abnormalities of pubertal development -Thyroid physiology and pathology -Congenital hypothyroidism: laboratory and clinical investigation of early detected infants -Physiology and pathology of adrenocortical function in infancy and childhood -Calcium homeostasis and disorders of bone and mineral metabolism -Neurohypophysis
-Diabetes Mellitus -Hypoglycemia. This book would be very useful for pediatricians, clinical physicians, endocrinologists, and physiologists. Mechanisms of Control of Gene Expression. UCLA Symposia on Molecular and Cellular Biology. New Series, Volume 67. Edited by B. CULLEN,L. P. GAGE, M. A. Q. SIDDIQUI, A. M. SKALKAand H. WEISSBACH. Published 1987 by Alan R. Liss, New York. No. of pages: 396. Price at September 1988: $85.00. ISBN: 0-8451-2660-O. This book contains the Proceedings of a Roche-UCLA Symposium held at Steamboat Springs, Colorado on March 29-Apri14, 1987. The field of the mechanism of control of gene expression has made an enormous impact in the last years due to advanced techniques for the control of mRNA, as well as its synthesis. This book contains the following main topics: --Gene regulation in prokaryotes -Gene regulation in eukaryotes (A) Transcriptional control mechanisms (B) DNA-protein interactions -mRNA splicing and regulation of translation -Control of stable RNA synthesis -Role of oncogene proteins in normal abnormal cellular responses. The different chapters have been written by eminent researchers in this field and the book would be very useful for people working in molecular biology, biochemistry, and physiology.
Molecnhu Biology of Intracellular Protein Sorting aod OrgaoelIe Assembly. UCLA Symposia on Molecular and Cellular Biology. New Series, Volume 76. Edited by R. A. BRADSHAW, L. MCALISTER-HENN and M. G. DOUGLAS. Published 1988 by Alan R. Liss, New York. No. of pages: 226. ISBN: O-8451-2675-X. This book contains scientific information presented at the DuPont-UCLA Symposium “Molecular Biology of Intracellular Protein Sorting and Organelle Assembly” held at Taos, New Mexico on 30 Januarv-5 Februarv. 1987. The last several years have seen majo; advances in.our understanding of how co- and post-translational modifications of proteins, synthesized in the cytoplasm of eukaryotic ceils, direct these molecules to their final intra- or extra-cellular sites of action. The following topics are covered in this book: -Cytoplasmic -Cytoplasmic -Intracellular -Intracellular
sorting: co- and post-translational sorting: organelle formation transport: ER/GOLGI transport: recycling.
events
This book would be very useful for molecular biologists, biochemists and physiologists.
MaxwellPergamon Macmillan pk. Printed in Great Britain
BOOK REVIEWS
Structwe and Function of Major and Minor SmaB Nuclear the very extensive area of the action of hormones in most Ribonucleoproteio Particles. Edited by M. L. BIRNSTIEL. endocrine cancers and includes the following main sections: Published 1988 by Springer-Verlag, Berlin. No. of pages: -Hormone receptors 216. Price: DM 198 (hard cover). ISBN: 3-540-18410-4. -Antibodies to hormone receptors -Hormonal regulation of gene expression In the last decade there was a big advance in the study of -Control of cell proliferation small nuclear ribonucleoproteins and the process of the -Growth factors mechanism of catalysis in RNA processing. This book -Biology of tumor spread contains up-to-date information on these problems and -Tumor markers includes the following main chapters: -Enzyme inhibitors -Small nuclear RNAs: RNA sequences, structure, and -Antihormones modifications -Breast cancer -The genes and transcription of the major small nuclear -Endometrial cancer RNAs -Prostate cancer -snRNP proteins -Lung, kidney and gastrointestinal cancer. -UsnRNP assembly and transport This book is very useful for people working in oncology, -Functions of the abundant U-snRNPs general clinicians, and advanced students in physiology, -Structure and function of minor snRNPs biochemistry and molecular biology. -Ribonuclease-P as a snRNP --Genetic
analysis of yeast snRNAs.
This book is very useful for researchers working in molecular biology, biochemistry, biophysics and biology.
In EnxymoIogy. Editors-in-Chief: SIDNEY P. and NATHAN0. KAPLAN Vol. 147: Pep& Growth Faetora-Part B. Edited by DAVID BARNWand D~vm A. SUUMSKU.Published 1987 by Academic Press, San Diego. No. of pages: 488. Price as at December 1988: $65.00. ISBN: o-12-182047-5.
Development
nod ReeognItIoo of the Tras&xmed CeB. Edited by MARK I. GREENEand Toarrrvu~~ HAMAOKA. Published 1987 by Plenum Press, New York. No. of pages: 460. Price as at March 1988: S65.00. ISBN: O-306-42636-6.
M&ads
CCJLOWICK
In the last years one of the most important impacts in biological. research has been the exploration of the mechanisms through which normal cells are transformed into malignant cells. This book contains upto-date information on this problem and the main topics concerned are as follows:
In recent years one of the biggest discoveries in biology was the presence of growth factors which are involved in many organs of different animal species, and one of the most important functions of this factor concerns cell proliferation. This book gives a general outline of recent information concerning different growth factors which include:
-Cytogenetics of neoplasia -The structure and function of the normal c-myc gene and its alteration in malignant cells -Protooncogene expression in lymphoid cells: implications for the regulation of normal cellular growth -0ncogene products as receptors -Monoclonal antibodies reactive with the neu oncogene -Platelet-derived growth factor product inhibit the neoplastic properties of neu-trans-Angiogenesis, endothelial and fibroblast growth factors formed cells -Nerve and glial growth factors -Relationship of the c-fm protooncogene product to the -Transferrin, erythropoietin, and related factors CSF-1 receptor -Techniques for the study of growth factor activity: genetic -Two &l-related protooncogenes encoding growth approaches and biological effects. factor receptors -The receptor for epidermal growth factor In each section is treated the chemical composition of -The role of the ubl gene in transformation growth factors, receptors, biological function and interac-Comparison of the structural and functional properties of tion with other growth factors in the different organelles of the viral and cellular WCgene products the cells. -Protein kinase C as the site of action of the phorbol ester This book is very useful for researchers in molecular tumor promoters endocrinology, biology, biochemistry, and physiology. -Involvement of human retrovirus in specific T-cell leukemia -Mechanisms of virus-induced alterations of expression of Class I genes and their role on tumorigenesis Hormones and Cancer, Volume 3. Series: Progress in Cancer Research and Therapy, Vol. 35. Edited by F. BREWANI, -Antigenic requirements for the recognition of Maloney murine leukemia virus-induced tumors by cytotoxic T ROGERJ. B. KING, MARC E. LIPPMANand JEAN-PIERRE lymphocytes RAYNAUD.Published 1988 by Raven Press, New York. No. of pages: 576. ISBN: O-88167-453-2. -SV40 tumor antigen: importance of cell surfact localixation in transformation and immunological control of neoplasia This book contains the Proceedings of the Third International Congress on Hormones and Cancer, held in Hamburg -Correlation of natural killer cell recognition with ras oncogene expression (Federal Republic of Germany) in September 1987. It covers 147
148
Book reviews
-A
regulatory role of natural killer cells (LGL) in T-cellmediated immune response -Immune regulation in neoplasia: dominance of suppressor systems -The generation and down-regulation of the immune response to progressive tumors -Origin and significance of transplantation antigens induced on cells transformed by UV radiation -Cellular and molecular mechanisms involved in tumor eradication in uiuo -Application of T-cell-T-cell interaction to enhanced tumor-specific immunity capable of eradicating tumor cells in vivo -Antigens expressed by melanoma and melanocytes: studies of the immunology, biology and genetics of melanoma -Malignant transformational changes of the sugar chains of glycoproteins and their clinical application -Ganglioside involvement in tumor cell-substratum interactions -Specific adoptive therapy of disseminated tumors: requirements for therapeutic efficacy and mechanisms by which T-cells mediate tumor eradication. This book would be useful for oncologists, clinicians, physiologists, biochemists, and researchers working in molecular biology. Pediatric Endocrinology-2nd Edition. Edited by R. COLLU, J. R. DUCHARME and H. J. GWDA. Comprehensive Endocrinology (Revised Series). Series editor: L. MARTINI. Published 1988 bv Raven Press. New York No. of oases: 704. Price as of December 1988: $177.50. ISBN: 0-8’8ik7477-X. This is an up-to-date book on most problems concerning pediatric endocrinology and contains major advances in pathophysiology, pharmacology, molecular biology and neuroregulatory mechanisms. The main topics covered are: -Neuroendocrine control of pituitary hormone secretion -Mechanisms of polypeptide hormone action: current concepts -Steroid hormone action --Ontogeny of pituitary hormone secretion -Abnormalities of growth --Insulin-like growth factors -Sexual differentiation -Molecular genetic approaches to testis differentiation -Normal puberty: clinical manifestations and their endocrine control -Abnormalities of pubertal development -Thyroid physiology and pathology -Congenital hypothyroidism: laboratory and clinical investigation of early detected infants -Physiology and pathology of adrenocortical function in infancy and childhood -Calcium homeostasis and disorders of bone and mineral metabolism -Neurohypophysis
-Diabetes Mellitus -Hypoglycemia. This book would be very useful for pediatricians, clinical physicians, endocrinologists, and physiologists. Mechanisms of Control of Gene Expression. UCLA Symposia on Molecular and Cellular Biology. New Series, Volume 67. Edited by B. CULLEN,L. P. GAGE, M. A. Q. SIDDIQUI, A. M. SKALKAand H. WEISSBACH. Published 1987 by Alan R. Liss, New York. No. of pages: 396. Price at September 1988: $85.00. ISBN: 0-8451-2660-O. This book contains the Proceedings of a Roche-UCLA Symposium held at Steamboat Springs, Colorado on March 29-Apri14, 1987. The field of the mechanism of control of gene expression has made an enormous impact in the last years due to advanced techniques for the control of mRNA, as well as its synthesis. This book contains the following main topics: --Gene regulation in prokaryotes -Gene regulation in eukaryotes (A) Transcriptional control mechanisms (B) DNA-protein interactions -mRNA splicing and regulation of translation -Control of stable RNA synthesis -Role of oncogene proteins in normal abnormal cellular responses. The different chapters have been written by eminent researchers in this field and the book would be very useful for people working in molecular biology, biochemistry, and physiology.
Molecnhu Biology of Intracellular Protein Sorting aod OrgaoelIe Assembly. UCLA Symposia on Molecular and Cellular Biology. New Series, Volume 76. Edited by R. A. BRADSHAW, L. MCALISTER-HENN and M. G. DOUGLAS. Published 1988 by Alan R. Liss, New York. No. of pages: 226. ISBN: O-8451-2675-X. This book contains scientific information presented at the DuPont-UCLA Symposium “Molecular Biology of Intracellular Protein Sorting and Organelle Assembly” held at Taos, New Mexico on 30 Januarv-5 Februarv. 1987. The last several years have seen majo; advances in.our understanding of how co- and post-translational modifications of proteins, synthesized in the cytoplasm of eukaryotic ceils, direct these molecules to their final intra- or extra-cellular sites of action. The following topics are covered in this book: -Cytoplasmic -Cytoplasmic -Intracellular -Intracellular
sorting: co- and post-translational sorting: organelle formation transport: ER/GOLGI transport: recycling.
events
This book would be very useful for molecular biologists, biochemists and physiologists.