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Dietary Influences on Free Insulin-Like Growth Factor-1
TUESDAY, OCTOBER 2
POSTER SESSION: WELLNESS AND PUBLIC HEALTH Title: MOTIVATIONAL INFLUENCES FOR PARTICIPATING IN A WORKSITE WELLNESS PROGRAM Author(s): A. R. Mobley, H. Lawyer, J. Faith, S. L. Mobley; Foods and Nutrition, Purdue University, West Lafayette, IN Learning Outcome: To identify the primary motivational influences of adults for participating in a worksite wellness program and making health behavior changes. Text: Understanding the underlying motivators for individual health behavior change to prevent chronic diseases is important due to increasing health care costs and increasing disease prevalence. It remains unclear what type of motivators are strongest in changing health related behaviors. The purpose of this study was to investigate motivators related to participation in a behavioral-based wellness program (“Healthy Purdue”) in the workplace. As part of Healthy Purdue, 8,798 men and women (Ages: 46.4 ⫾ 11.6) were enrolled in a wellness program. A subpopulation of this cohort (n ⫽ 314) completed a brief questionnaire to assess motivators for participation. Chi-square analysis revealed that concerns for one’s health (40%) was the primary motivator (p⬍0.0001) to participate in Healthy Purdue followed by a monetary incentive of ⬃$100 (28%), self-no specific reason (19%), family member (11%), friend (⬍1%), health professional (⬍1%), and other (⬍1%). Participants reported that concerns for one’s health (62%) was also the primary motivator (p⬍0.0001) to make actual changes to improve health followed by motivations from self-no specific reason (23%), family member (11%), monetary incentive (2%), health professional (2%), friend (⬍1%), and other (⬍1%). Findings from this study show that the primary motivator to participate in a wellness program and/or make changes to improve health is the concern for one’s health. A monetary incentive appears to be a secondary motivator to participate in a wellness program but not a strong motivator to make changes to improve health.
Title: KIDS CHOOSE TO BE HEALTHY Author(s): P. A. Hill, L. Lovgren; Nutrition Services, Kent Hospital, Warwick, RI Learning Outcome: Participants will be able to identify a minimum of two successful interventions that were utilized in this health and fitness program targeting overweight/obese children. Text: Children in Rhode Island are part of a nationwide obesity epidemic with over 26% overweight or obese. This trend has devastating consequences including early onset diabetes, hyperlipdemia, hypertension, and psychosocial impairment. Kent Hospital recognized this crisis by supporting the state’s first grant funded behavioral program targeting overweight children. This program has been ongoing in schools and health centers since 2003, with 285 children attending 23 eight week sessions. Target audience is overweight children between 6-10 years old with BMI at or above the 95th percentile. The intervention is eight - 1 1⁄2 hour classes, attended by children and family members, with follow-up sessions. Classes offer nutrition/self esteem and physical activity education, presented by 2 registered dietitians and 1 exercise physiologist. Participants are recruited state wide, using advertisements, referrals from health care providers, school nurses, and past participants. Data is collected using pre/post surveys, pre/post body measurements (BMI), and food/activity journals. Key results of intervention: ● 88% increase consumption fruits and vegetables ● 60% increase consumption whole grains ● 45% increase in child’s physical activity outside of school ● 65% decrease in screen time ● 56% increase in parental physical activity ● 72% of participants demonstrated decreased BMI Overweight children demonstrate positive behavioral changes as a result of participating in a family centered program targeting specific health habits. Program recognition: ● Winner of 2005 Care Award for innovation and customer focus by Care New England Hospital group ● Published in RI Kids Count Issue Brief 2006
Funding Disclosure: RIGA 2001 & BCBS grant 2002-2004, none at this time
Funding Disclosure: Oncological Sciences Center, Purdue University
Title: BIO-MEDICINAL EFFECT OF SWEET POTATO IN PEOPLE WITH DIABETES
Title: DIETARY INFLUENCES ON FREE INSULIN-LIKE GROWTH FACTOR-1
Author(s): J. W. McClelland,1 J. C. Allen,2 S. Zakir3; 14-H, Youth Development, and Family and Consumer Sciences, North Carolina State University, Cary, NC, 2Food Science, North Carolina State University, Raleigh, NC, 3Model College, Islamabad, Pakistan
Author(s): J. P. Karl,1 C. Koenig,1 J. S. Staab,1 J. A. Alemany,1 W. J. Kraemer,2 A. J. Young,1 B. C. Nindl1; 1US Army Research Institute of Environmental Medicine, Natick, MA, 2University of Connecticut, Stoors, CT
Learning Outcome: Discuss the potential application of sweet potatoes in the diet of persons with diabetes Text: Diabetes is predicted to rise from 135,000,000 currently to 333,000,000 by 2025. Low Glycemic Index (GI) foods may help control blood glucose (BG) in diabetics. Our objective was to investigate GI of sweetpotato. We measured the change in BG after consumption of two dehydrated sweetpotato cultivars in 40 participants (20 non-diabetic and 20 diabetic) from Faisalabad, Pakistan. Demographics of the two groups were similar: age (41); weight (148 pounds); height (64”); and BMI (24.55). Participants received 50g carbohydrate from each source (glucose, White Star (Pakistan) - whole and skin only, and Beauregard (U.S.)); BG was measured at 0, 1, and 2 hr, and insulin at 0 and 2 hr. GI of White Star was 44.2 in non-diabetic and 28.5 in diabetic subjects. GI of Beauregard was 32.1 in non-diabetic and 30.3 in diabetic subjects. In both groups, the skin of the White Star caused an immediate and sustained drop in the BG, even though the meal contained 50g of carbohydrate. The CV for the BG measurements were 19.6% in non-diabetic and 39.3% in diabetic subjects. The servings of dehydrated White Star and Beauregard and White Star skin were evaluated by 5 judges for sensory attributes (color, flavor, taste, and texture). On a 0-9 point hedonic scale, overall Beauregard score was 7.7 ⫾ 0.26 followed by White Star 7.1 ⫾ 0.24 and 6.5 ⫾ 0.18 for White Star skin. Beauregard faired better in all attributes. As consumption of sweetpotatoes lowered BG in diabetic participants, this vegetable may aid in diabetes management. Funding Disclosure: None A-104 / August 2007 Suppl 3—Abstracts Volume 107 Number 8
Learning Outcome: To explore relationships between dietary factors and biologically active insulin-like growth factor-1. Text: Insulin-like growth factor (IGF)-1 is a metabolic-regulatory hormone that mediates a variety of functional effects. For example, it is thought that elevated IGF-1 levels protect against osteoporosis and sarcopenia, but are also linked to increased cancer risk. Independent associations between serum total IGF-1 and dietary intake of energy, protein, alcohol, minerals, dairy, isoflavones and lycopene have been documented; however, less is known about dietary influences on free (biologically active) IGF-1. We examined the relationships between dietary factors and free IGF-1 concentration measured by commercially available immunoassays in twenty-eight college-aged women ([mean⫾SD], 20 ⫾ 2 yrs, BMI 24.0 ⫾ 4.2 kg/m2). Diet was assessed using a food frequency questionnaire. The age-, BMI- and energy-adjusted associations of free IGF-1 with dietary factors were determined by correlation and linear regression analysis. Dietary factors of interest were split by level of intake and mean free IGF-1 compared between these groups by univariate ANOVA. Positive relationships were observed between free IGF-1 and energy (r⫽ 0.41, p⬍0.04), protein (r⫽ 0.49, p⫽0.01), and zinc (r⫽ 0.52, p⬍0.01) intakes and daily meat servings (r⫽ 0.51, p⬍0.01). Linear regression showed that 41% of the variation in free IGF-1 could be attributed to energy and zinc intakes. Analysis between low and high categories of nutrient intakes showed a significant increase in mean free IGF-1 with increasing energy (pⱕ0.01) and zinc (p⬍0.02) intakes, and daily meat servings (pⱕ0.01). Our data suggest that the possible link between IGF-1 bioactivity and disease risk may be modulated by total energy, protein and zinc intakes. Funding Disclosure: US Army Medical Research and Materiel Command
POSTER SESSION: WELLNESS AND PUBLIC HEALTH Title: MOTIVATIONAL INFLUENCES FOR PARTICIPATING IN A WORKSITE WELLNESS PROGRAM Author(s): A. R. Mobley, H. Lawyer, J. Faith, S. L. Mobley; Foods and Nutrition, Purdue University, West Lafayette, IN Learning Outcome: To identify the primary motivational influences of adults for participating in a worksite wellness program and making health behavior changes. Text: Understanding the underlying motivators for individual health behavior change to prevent chronic diseases is important due to increasing health care costs and increasing disease prevalence. It remains unclear what type of motivators are strongest in changing health related behaviors. The purpose of this study was to investigate motivators related to participation in a behavioral-based wellness program (“Healthy Purdue”) in the workplace. As part of Healthy Purdue, 8,798 men and women (Ages: 46.4 ⫾ 11.6) were enrolled in a wellness program. A subpopulation of this cohort (n ⫽ 314) completed a brief questionnaire to assess motivators for participation. Chi-square analysis revealed that concerns for one’s health (40%) was the primary motivator (p⬍0.0001) to participate in Healthy Purdue followed by a monetary incentive of ⬃$100 (28%), self-no specific reason (19%), family member (11%), friend (⬍1%), health professional (⬍1%), and other (⬍1%). Participants reported that concerns for one’s health (62%) was also the primary motivator (p⬍0.0001) to make actual changes to improve health followed by motivations from self-no specific reason (23%), family member (11%), monetary incentive (2%), health professional (2%), friend (⬍1%), and other (⬍1%). Findings from this study show that the primary motivator to participate in a wellness program and/or make changes to improve health is the concern for one’s health. A monetary incentive appears to be a secondary motivator to participate in a wellness program but not a strong motivator to make changes to improve health.
Title: KIDS CHOOSE TO BE HEALTHY Author(s): P. A. Hill, L. Lovgren; Nutrition Services, Kent Hospital, Warwick, RI Learning Outcome: Participants will be able to identify a minimum of two successful interventions that were utilized in this health and fitness program targeting overweight/obese children. Text: Children in Rhode Island are part of a nationwide obesity epidemic with over 26% overweight or obese. This trend has devastating consequences including early onset diabetes, hyperlipdemia, hypertension, and psychosocial impairment. Kent Hospital recognized this crisis by supporting the state’s first grant funded behavioral program targeting overweight children. This program has been ongoing in schools and health centers since 2003, with 285 children attending 23 eight week sessions. Target audience is overweight children between 6-10 years old with BMI at or above the 95th percentile. The intervention is eight - 1 1⁄2 hour classes, attended by children and family members, with follow-up sessions. Classes offer nutrition/self esteem and physical activity education, presented by 2 registered dietitians and 1 exercise physiologist. Participants are recruited state wide, using advertisements, referrals from health care providers, school nurses, and past participants. Data is collected using pre/post surveys, pre/post body measurements (BMI), and food/activity journals. Key results of intervention: ● 88% increase consumption fruits and vegetables ● 60% increase consumption whole grains ● 45% increase in child’s physical activity outside of school ● 65% decrease in screen time ● 56% increase in parental physical activity ● 72% of participants demonstrated decreased BMI Overweight children demonstrate positive behavioral changes as a result of participating in a family centered program targeting specific health habits. Program recognition: ● Winner of 2005 Care Award for innovation and customer focus by Care New England Hospital group ● Published in RI Kids Count Issue Brief 2006
Funding Disclosure: RIGA 2001 & BCBS grant 2002-2004, none at this time
Funding Disclosure: Oncological Sciences Center, Purdue University
Title: BIO-MEDICINAL EFFECT OF SWEET POTATO IN PEOPLE WITH DIABETES
Title: DIETARY INFLUENCES ON FREE INSULIN-LIKE GROWTH FACTOR-1
Author(s): J. W. McClelland,1 J. C. Allen,2 S. Zakir3; 14-H, Youth Development, and Family and Consumer Sciences, North Carolina State University, Cary, NC, 2Food Science, North Carolina State University, Raleigh, NC, 3Model College, Islamabad, Pakistan
Author(s): J. P. Karl,1 C. Koenig,1 J. S. Staab,1 J. A. Alemany,1 W. J. Kraemer,2 A. J. Young,1 B. C. Nindl1; 1US Army Research Institute of Environmental Medicine, Natick, MA, 2University of Connecticut, Stoors, CT
Learning Outcome: Discuss the potential application of sweet potatoes in the diet of persons with diabetes Text: Diabetes is predicted to rise from 135,000,000 currently to 333,000,000 by 2025. Low Glycemic Index (GI) foods may help control blood glucose (BG) in diabetics. Our objective was to investigate GI of sweetpotato. We measured the change in BG after consumption of two dehydrated sweetpotato cultivars in 40 participants (20 non-diabetic and 20 diabetic) from Faisalabad, Pakistan. Demographics of the two groups were similar: age (41); weight (148 pounds); height (64”); and BMI (24.55). Participants received 50g carbohydrate from each source (glucose, White Star (Pakistan) - whole and skin only, and Beauregard (U.S.)); BG was measured at 0, 1, and 2 hr, and insulin at 0 and 2 hr. GI of White Star was 44.2 in non-diabetic and 28.5 in diabetic subjects. GI of Beauregard was 32.1 in non-diabetic and 30.3 in diabetic subjects. In both groups, the skin of the White Star caused an immediate and sustained drop in the BG, even though the meal contained 50g of carbohydrate. The CV for the BG measurements were 19.6% in non-diabetic and 39.3% in diabetic subjects. The servings of dehydrated White Star and Beauregard and White Star skin were evaluated by 5 judges for sensory attributes (color, flavor, taste, and texture). On a 0-9 point hedonic scale, overall Beauregard score was 7.7 ⫾ 0.26 followed by White Star 7.1 ⫾ 0.24 and 6.5 ⫾ 0.18 for White Star skin. Beauregard faired better in all attributes. As consumption of sweetpotatoes lowered BG in diabetic participants, this vegetable may aid in diabetes management. Funding Disclosure: None A-104 / August 2007 Suppl 3—Abstracts Volume 107 Number 8
Learning Outcome: To explore relationships between dietary factors and biologically active insulin-like growth factor-1. Text: Insulin-like growth factor (IGF)-1 is a metabolic-regulatory hormone that mediates a variety of functional effects. For example, it is thought that elevated IGF-1 levels protect against osteoporosis and sarcopenia, but are also linked to increased cancer risk. Independent associations between serum total IGF-1 and dietary intake of energy, protein, alcohol, minerals, dairy, isoflavones and lycopene have been documented; however, less is known about dietary influences on free (biologically active) IGF-1. We examined the relationships between dietary factors and free IGF-1 concentration measured by commercially available immunoassays in twenty-eight college-aged women ([mean⫾SD], 20 ⫾ 2 yrs, BMI 24.0 ⫾ 4.2 kg/m2). Diet was assessed using a food frequency questionnaire. The age-, BMI- and energy-adjusted associations of free IGF-1 with dietary factors were determined by correlation and linear regression analysis. Dietary factors of interest were split by level of intake and mean free IGF-1 compared between these groups by univariate ANOVA. Positive relationships were observed between free IGF-1 and energy (r⫽ 0.41, p⬍0.04), protein (r⫽ 0.49, p⫽0.01), and zinc (r⫽ 0.52, p⬍0.01) intakes and daily meat servings (r⫽ 0.51, p⬍0.01). Linear regression showed that 41% of the variation in free IGF-1 could be attributed to energy and zinc intakes. Analysis between low and high categories of nutrient intakes showed a significant increase in mean free IGF-1 with increasing energy (pⱕ0.01) and zinc (p⬍0.02) intakes, and daily meat servings (pⱕ0.01). Our data suggest that the possible link between IGF-1 bioactivity and disease risk may be modulated by total energy, protein and zinc intakes. Funding Disclosure: US Army Medical Research and Materiel Command