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EPICARDIAL FAT RATHER THAN ABDOMINAL VISCERAL FAT IS ASSOCIATED WITH LEFT VENTRICULAR DIASTOLIC DYSFUNCTION
E1081 JACC March 12, 2013 Volume 61, Issue 10
Imaging Epicardial Fat Rather than Abdominal Visceral Fat Is Associated with Left Ventricular Diastolic Dysfunction Poster Contributions Poster Sessions, Expo North Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Imaging: Cardiac Abnormalities in Non-Cardiac Disorders, Hand Held Echocardiography, Cardiac Masses Abstract Category: 18. Imaging: Echo Presentation Number: 1311-327 Authors: Norihisa Toh, Hitomi Sakamoto, Kazuhiro Osawa, Hiroki Oe, Toru Miyoshi, Kazufumi Nakamura, Hiroshi Ito, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan Background: Visceral adiposity is predictive of cardiovascular (CV) disease. Recently, visceral adiposity has been evaluated by echocardiographic epicardial fat thickness (EFT) as well as abdominal visceral fat area, but the relationship between fat distribution and CV risk is not well understood. Left ventricular (LV) diastolic dysfunction is also associated with an increased risk for CV disease. The present study was designed to determine whether fat distribution is related to LV diastolic dysfunction. Methods: Three hundred and forty-seven subjects with LV ejection fraction ≥ 50% and without CV disease were studied. All underwent echocardiography, multidetector computed tomography for abdominal visceral fat area, and measurement of serum BNP. Echocardiographic EFT was measured on the free wall of the right ventricle from a parasternal long-axis view at end-systole. Diastolic dysfunction was graded according to the recommendation. Results: EFT showed significant correlations with E/A (r = 0.14, p < 0.05), e’ (r = 0.15, p < 0.01), E/e’ (r = 0.18, p < 0.01), left atrial volume index (r = 0.18, p < 0.01), and log BNP (r = 0.16, p < 0.01). However, abdominal visceral fat area was correlated with E/A (r = 0.27, p < 0.01) and e’ (r = 0.17, p<0.01) only. EFT was increased with increasing degree of the diastolic dysfunction (p<0.05). Conclusions: Echocardiographic EFT is strongly associated with LV diastolic dysfunction compared with abdominal visceral fat area. CV risk may vary according to the fat distribution.
Imaging Epicardial Fat Rather than Abdominal Visceral Fat Is Associated with Left Ventricular Diastolic Dysfunction Poster Contributions Poster Sessions, Expo North Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Imaging: Cardiac Abnormalities in Non-Cardiac Disorders, Hand Held Echocardiography, Cardiac Masses Abstract Category: 18. Imaging: Echo Presentation Number: 1311-327 Authors: Norihisa Toh, Hitomi Sakamoto, Kazuhiro Osawa, Hiroki Oe, Toru Miyoshi, Kazufumi Nakamura, Hiroshi Ito, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan Background: Visceral adiposity is predictive of cardiovascular (CV) disease. Recently, visceral adiposity has been evaluated by echocardiographic epicardial fat thickness (EFT) as well as abdominal visceral fat area, but the relationship between fat distribution and CV risk is not well understood. Left ventricular (LV) diastolic dysfunction is also associated with an increased risk for CV disease. The present study was designed to determine whether fat distribution is related to LV diastolic dysfunction. Methods: Three hundred and forty-seven subjects with LV ejection fraction ≥ 50% and without CV disease were studied. All underwent echocardiography, multidetector computed tomography for abdominal visceral fat area, and measurement of serum BNP. Echocardiographic EFT was measured on the free wall of the right ventricle from a parasternal long-axis view at end-systole. Diastolic dysfunction was graded according to the recommendation. Results: EFT showed significant correlations with E/A (r = 0.14, p < 0.05), e’ (r = 0.15, p < 0.01), E/e’ (r = 0.18, p < 0.01), left atrial volume index (r = 0.18, p < 0.01), and log BNP (r = 0.16, p < 0.01). However, abdominal visceral fat area was correlated with E/A (r = 0.27, p < 0.01) and e’ (r = 0.17, p<0.01) only. EFT was increased with increasing degree of the diastolic dysfunction (p<0.05). Conclusions: Echocardiographic EFT is strongly associated with LV diastolic dysfunction compared with abdominal visceral fat area. CV risk may vary according to the fat distribution.