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Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and Foreign Antigens
Immunity
Retractions The Fas/Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and Foreign Antigens Luk Van Parijs, Daniel A. Peterson, and Abul K. Abbas* *Correspondence: [email protected] DOI 10.1016/j.immuni.2009.04.001
(Immunity 8, 254–274; February 1, 1998) The authors have agreed to retract this paper because of duplication of the flow cytometry dot plots in Figure 1 (labeled as 3A9/+, 3A9/lpr and 3A9/gld) by the first author. This figure shows TCR and the CD4 and CD8 coreceptor expression in cells expressing a single TCR (3A9) on the lpr or gld background, which is important for establishing that TCR and coreceptor expression is not perturbed by the abnormalities in Fas or Fas ligand. This matter was investigated by Harvard Medical School and Brigham and Women’s Hospital, as well as the Office of Research Integrity at the United States Department of Human Services, which found the first author to be responsible for the scientific misconduct pertaining to the issue described here. The authors stand by the validity of the other figures and sincerely apologize for the inconvenience caused by this retraction.
Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death Luk Van Parijs, Yosef Refaeli, James D. Lord, Brad H. Nelson, Abul K. Abbas, and David Baltimore* *Correspondence: [email protected] DOI 10.1016/j.immuni.2009.04.002
(Immunity 11, 281–288; September 1, 1999) The authors have agreed to retract this paper because of duplication of the flow cytometry dot plots in Figure 1C (labeled as WT and D355+8F) by the first author. This figure shows the reconstitution of mouse cells deficient in IL-2 receptor beta with various wild-type and mutant human IL-2 receptor beta chains. This data established the system used to test various properties of these receptor chains in the later work of the paper. This matter was investigated by the California Institute of Technology and the Office of Research Integrity at the United States Department of Human Services, which found the first author to be responsible for the scientific misconduct pertaining to the issue described here. The authors stand by the validity of the other figures and sincerely apologize for the inconvenience caused by this retraction.
Immunity 30, 611–612, April 17, 2009 ª2009 Elsevier Inc. 611
Retractions The Fas/Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and Foreign Antigens Luk Van Parijs, Daniel A. Peterson, and Abul K. Abbas* *Correspondence: [email protected] DOI 10.1016/j.immuni.2009.04.001
(Immunity 8, 254–274; February 1, 1998) The authors have agreed to retract this paper because of duplication of the flow cytometry dot plots in Figure 1 (labeled as 3A9/+, 3A9/lpr and 3A9/gld) by the first author. This figure shows TCR and the CD4 and CD8 coreceptor expression in cells expressing a single TCR (3A9) on the lpr or gld background, which is important for establishing that TCR and coreceptor expression is not perturbed by the abnormalities in Fas or Fas ligand. This matter was investigated by Harvard Medical School and Brigham and Women’s Hospital, as well as the Office of Research Integrity at the United States Department of Human Services, which found the first author to be responsible for the scientific misconduct pertaining to the issue described here. The authors stand by the validity of the other figures and sincerely apologize for the inconvenience caused by this retraction.
Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death Luk Van Parijs, Yosef Refaeli, James D. Lord, Brad H. Nelson, Abul K. Abbas, and David Baltimore* *Correspondence: [email protected] DOI 10.1016/j.immuni.2009.04.002
(Immunity 11, 281–288; September 1, 1999) The authors have agreed to retract this paper because of duplication of the flow cytometry dot plots in Figure 1C (labeled as WT and D355+8F) by the first author. This figure shows the reconstitution of mouse cells deficient in IL-2 receptor beta with various wild-type and mutant human IL-2 receptor beta chains. This data established the system used to test various properties of these receptor chains in the later work of the paper. This matter was investigated by the California Institute of Technology and the Office of Research Integrity at the United States Department of Human Services, which found the first author to be responsible for the scientific misconduct pertaining to the issue described here. The authors stand by the validity of the other figures and sincerely apologize for the inconvenience caused by this retraction.
Immunity 30, 611–612, April 17, 2009 ª2009 Elsevier Inc. 611