Handbook of Anxiety, Vol. 5: Contemporary Issues and Prospects for Research in Anxiety Disorders

Handbook of Anxiety, Vol. 5: Contemporary Issues and Prospects for Research in Anxiety Disorders

544 European Neuropsychopharmacology, 3 (1993) 544 © 1993 Elsevier Science Publishers B.V. All rights reserved 0924-977X/93/$05.00 NEUPSY 00108 Boo...

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544

European Neuropsychopharmacology, 3 (1993) 544 © 1993 Elsevier Science Publishers B.V. All rights reserved 0924-977X/93/$05.00

NEUPSY 00108

Book review

Handbook of Anxiety, Vol. 5: Contemporary Issues and Prospects for Research in Anxiety Disorders, b y G . D . B u r r o w s , M . R o t h a n d R. N o y e s Jr. ( e d i t o r s ) , E l s e v i e r , A m s t e r d a m , 1992 As the fifth and final volume in this series on anxiety the emphasis on new prospects in research is appropriate. Among the contemporary issues discussed there was a reasonable balance between chapters reviewing behavioral treatment and those emphasizing biological therapy. Most appreciated were chapters reviewing comorbidity of anxiety and depression, the hazards of benzodiazepine therapy, the review of benzodiazepine receptor function in panic disorder, as well as the chapters reviewing aspects of anxiety disorders in children. Of particular interest and importance is the chapter highlighting the incidence of suicide in panic disorder patients. In a book dedicated to research in anxiety it is noteworthy that the area of research with cholecystokinin (CCK) in panic and anxiety disorders has been completely overlooked. In the chapter on benzodiazepine receptor function it could have been mentioned that flumazanil does not inhibit the panic inducing effect of CCK (Bradwejn et al., in press).

At the very forefront of research in anxiety is the development of new types of anxiolytics. The review of glycinergic ligands as novel anxiolytics, acting on NMPA receptors, is of particular interest. It is noted again though that the potential role of CCK antagonists as novel anxiolytics is neither reviewed nor discussed. In general, chapters are well laid out and follow in a reasonable order. The tables are for the most part helpful. In conclusion, this book has much to offer those wanting an update on recent issues and research in the area of anxiety.

Reference Bradwejn, J. et al. (in press) The effects of flumazenil on cholecystokinin-tetrapeptide-induced panic symptoms in healthy volunteers. Presented in part at the American Psychiatric Association, Annual Meeting, Washington, DC, 1992.