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High Performance Liquid Chromatography in Biotechnology
626
ANALYTICA
tion of the book. It contains a presentation of algorithms for 50 subprogram modules with mathematic prmciples and discussions of then properties. Complete listings in Fortran 77 are provided m an Appendix and on a floppy disk, which is supplied with the book, for IBM personal microcomputers. Two introductory chapters deal with the fundamentals of digital signal processing and sampling of data and provide background and notation for other chapters. The next chapter, in which the first algorithms are discussed, concerns the most common signal transformation used m digital signal processing, namely discrete Fourier transform. All the algonthms presented are accompamed by examples of their use, exercises and a list of references. Three chapters are devoted to filtering and filters design, including filtering algorithms for direct, cascade, parallel and lattice structures, digital finite and infmtte response filtering. The next chapters concern fast convolution and correlation algorithms, then algorithms of decimation and mterpolation and discussion of least-squares-system design techniques mcludmg algorithms for designing optimum systems. The last two chapters present routines to enable the computation of basic statistical parameters, curve-fitting routines and routines for data wmdows, phase unwrapping and unusual transforms. It is imposstble to present here a complete list of discussed problems and methods of signal processing of common potential use in physicochemical measurements. All the algorithms presented are well illustrated with relevant examples. The text is clear and provides numerous references to other textbooks and original papers. This is a book for a large circle of potential readers, winch should include analytical chemists. Marek TroJanowicz
W.S. Hancock (Ed.), Hzgh Performance Lzquzd Chromatography zn Bzotechnology, Wiley, New York, 1990 (ISBN 0-471-82584-O). x + 564 pp. Price E74.35. Liquid chromatography (LC) has had a major influence on the development of new analytical
CHIMICA
ACTA
methodologtes for the characterisation of brotechnology products. Well known LC techniques, e.g. reversed phase, ion exchange, affinity and hydrophobic interaction have all been widely used and specific separation strategies, e.g. for nucleic acid purification, have been developed. This book contams 16 chapters written by contributors from USA, Japan, Denmark and Sweden. There are general chapters on the design of bonded phases, adsorption of proteins on alkylsdica, scale up of protein separations and high-performance ion-exchange and affinity chromatography. Chapters on specific applications cover insulin, antigens, vaccines, human growth hormone, polypeptides, ohgodeoxyribonucleotides and antibodies. It is generally well presented with up to date references and a good index. The contents provide a good overview of the application of LC in biotechnology and it is therefore a useful reference text for chemists and engineers working in that industry. P.J. Worsfold
Klaus K. Unger (Ed.), Packrngs and Stationary Phases zn Chromatographzc Technzques (Chromatographzc Sczence Serzes, Vol. 47), Dekker, New York, 1990 (ISBN 0-8247-7940-l). vm + 836 pp. Price US$lSO.OO (USA and Canada), US$180.00 (all other countries). The packings and stationary phases are, of course, critical components of all chromatographic techniques. This discussion of such materials for all types of chromatography, by a collection of eminent scientists, is therefore very welcome. The book begins with a historical account of the subject, followed by a general survey of the role of packing types on separations. There are extensive contributions on stationary phases in gas chromatography (Porschmann and Engewald) and in liquid chromatography (Unger), as well as chapters on thin-layer, size-exclusion, donor-acceptor, hgand-exchange, ion-pair and affinity chromatography. There is also a long discussion on ion exchangers (Pietrzyk) and, finally, a chapter on
ANALYTICA
tion of the book. It contains a presentation of algorithms for 50 subprogram modules with mathematic prmciples and discussions of then properties. Complete listings in Fortran 77 are provided m an Appendix and on a floppy disk, which is supplied with the book, for IBM personal microcomputers. Two introductory chapters deal with the fundamentals of digital signal processing and sampling of data and provide background and notation for other chapters. The next chapter, in which the first algorithms are discussed, concerns the most common signal transformation used m digital signal processing, namely discrete Fourier transform. All the algonthms presented are accompamed by examples of their use, exercises and a list of references. Three chapters are devoted to filtering and filters design, including filtering algorithms for direct, cascade, parallel and lattice structures, digital finite and infmtte response filtering. The next chapters concern fast convolution and correlation algorithms, then algorithms of decimation and mterpolation and discussion of least-squares-system design techniques mcludmg algorithms for designing optimum systems. The last two chapters present routines to enable the computation of basic statistical parameters, curve-fitting routines and routines for data wmdows, phase unwrapping and unusual transforms. It is imposstble to present here a complete list of discussed problems and methods of signal processing of common potential use in physicochemical measurements. All the algorithms presented are well illustrated with relevant examples. The text is clear and provides numerous references to other textbooks and original papers. This is a book for a large circle of potential readers, winch should include analytical chemists. Marek TroJanowicz
W.S. Hancock (Ed.), Hzgh Performance Lzquzd Chromatography zn Bzotechnology, Wiley, New York, 1990 (ISBN 0-471-82584-O). x + 564 pp. Price E74.35. Liquid chromatography (LC) has had a major influence on the development of new analytical
CHIMICA
ACTA
methodologtes for the characterisation of brotechnology products. Well known LC techniques, e.g. reversed phase, ion exchange, affinity and hydrophobic interaction have all been widely used and specific separation strategies, e.g. for nucleic acid purification, have been developed. This book contams 16 chapters written by contributors from USA, Japan, Denmark and Sweden. There are general chapters on the design of bonded phases, adsorption of proteins on alkylsdica, scale up of protein separations and high-performance ion-exchange and affinity chromatography. Chapters on specific applications cover insulin, antigens, vaccines, human growth hormone, polypeptides, ohgodeoxyribonucleotides and antibodies. It is generally well presented with up to date references and a good index. The contents provide a good overview of the application of LC in biotechnology and it is therefore a useful reference text for chemists and engineers working in that industry. P.J. Worsfold
Klaus K. Unger (Ed.), Packrngs and Stationary Phases zn Chromatographzc Technzques (Chromatographzc Sczence Serzes, Vol. 47), Dekker, New York, 1990 (ISBN 0-8247-7940-l). vm + 836 pp. Price US$lSO.OO (USA and Canada), US$180.00 (all other countries). The packings and stationary phases are, of course, critical components of all chromatographic techniques. This discussion of such materials for all types of chromatography, by a collection of eminent scientists, is therefore very welcome. The book begins with a historical account of the subject, followed by a general survey of the role of packing types on separations. There are extensive contributions on stationary phases in gas chromatography (Porschmann and Engewald) and in liquid chromatography (Unger), as well as chapters on thin-layer, size-exclusion, donor-acceptor, hgand-exchange, ion-pair and affinity chromatography. There is also a long discussion on ion exchangers (Pietrzyk) and, finally, a chapter on