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JAAD Game Changers: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients
Journal Pre-proof JAAD Game Changers: Pemphigus and hematologic malignancies: A populationbased study of 11,859 patients Eden Lake PII:
S0190-9622(19)33138-X
DOI:
https://doi.org/10.1016/j.jaad.2019.11.046
Reference:
YMJD 14029
To appear in:
Journal of the American Academy of Dermatology
Received Date: 22 November 2019 Accepted Date: 22 November 2019
Please cite this article as: Lake E, JAAD Game Changers: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients, Journal of the American Academy of Dermatology (2020), doi: https://doi.org/10.1016/j.jaad.2019.11.046. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier on behalf of the American Academy of Dermatology, Inc.
Title Page Author: (Corresponding Author) Eden Lake Loyola University Medical Center Medicine, Division Dermatology 321 N. La Grange Rd. La Grange Park, IL 60526 7084851271 [email protected] Funding: None Conflicts: None Words: 151 Article Title: JAAD Game Changers: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients
Game Changer Information Game Changer Category: General Derm Game Changer Title: Game Changer: Pemphigus and hematologic malignancies: A populationbased study of 11,859 patients Game Changer Author: Eden Lake, MD Game Changer: • •
This point is critical in autoimmune dermatoses as risk of malignancy is always discussed with immunosuppressant medication. This will factor into our discussion of cancer risk with mycophenolate mofetil, azathioprine, etc. as these patients with pemphigus are already at higher risk for leukemia and lymphoma. Original Article Information
Original authors: Khalaf Kridin, MD, Shira Zelber-Sagi, PhD, Doron Comaneshter, PhD, Erez Batat, PhD, Arnon D. Cohen, MD, PhD Original Article Title: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients Original Capsule Summary: • • •
Hematologic malignancies have been reported sporadically in patients with pemphigus. In the current study, significant associations were observed between pemphigus and chronic leukemia, multiple myeloma, and non-Hodgkin lymphoma. Further research is needed to confirm these findings in other cohorts.
Link to the original article: https://www.jaad.org/article/S0190-9622(17)32738-X/fulltext
S0190-9622(19)33138-X
DOI:
https://doi.org/10.1016/j.jaad.2019.11.046
Reference:
YMJD 14029
To appear in:
Journal of the American Academy of Dermatology
Received Date: 22 November 2019 Accepted Date: 22 November 2019
Please cite this article as: Lake E, JAAD Game Changers: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients, Journal of the American Academy of Dermatology (2020), doi: https://doi.org/10.1016/j.jaad.2019.11.046. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier on behalf of the American Academy of Dermatology, Inc.
Title Page Author: (Corresponding Author) Eden Lake Loyola University Medical Center Medicine, Division Dermatology 321 N. La Grange Rd. La Grange Park, IL 60526 7084851271 [email protected] Funding: None Conflicts: None Words: 151 Article Title: JAAD Game Changers: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients
Game Changer Information Game Changer Category: General Derm Game Changer Title: Game Changer: Pemphigus and hematologic malignancies: A populationbased study of 11,859 patients Game Changer Author: Eden Lake, MD Game Changer: • •
This point is critical in autoimmune dermatoses as risk of malignancy is always discussed with immunosuppressant medication. This will factor into our discussion of cancer risk with mycophenolate mofetil, azathioprine, etc. as these patients with pemphigus are already at higher risk for leukemia and lymphoma. Original Article Information
Original authors: Khalaf Kridin, MD, Shira Zelber-Sagi, PhD, Doron Comaneshter, PhD, Erez Batat, PhD, Arnon D. Cohen, MD, PhD Original Article Title: Pemphigus and hematologic malignancies: A population-based study of 11,859 patients Original Capsule Summary: • • •
Hematologic malignancies have been reported sporadically in patients with pemphigus. In the current study, significant associations were observed between pemphigus and chronic leukemia, multiple myeloma, and non-Hodgkin lymphoma. Further research is needed to confirm these findings in other cohorts.
Link to the original article: https://www.jaad.org/article/S0190-9622(17)32738-X/fulltext