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La fibrose pulmonaire des mineurs
Book Reviews LA Rt~ACTION D E F I X A T I O N DANS LES T U B E R C U L O S E S H U M A I N E S E T ANIMALES. By A. URBAIN. 2nd ed. Masson. Paris. I937. pp. I46. 28 ft.
LA FIBROSE P U L M O N A I R E DES M I N E U R S . By L. CROIZIER, E. MARTIn and A. POLICARD. Paris. Masson et Cie. pp. 2i 4. Illustrated. Price I65 fr.
In view of the extensive literature on tile tuberculous complement fixation reaction accumulated during the last twenty years and the progress made in the study of the nature of this reaction, a review of the whole problem is welcome. Dealing first with the technique of the reaction the author gives a detailed description of the preparation of the various antigens recommended and then reviews the different methods for examining complement fixing antibodies. A short discussion on the chemical nature of the antigen follows, in which the non-lipoid antigen which has lately been the object of ' much investigation could perhaps have been treated more fully. Reviewing the results reported to have been obtained with the various antigens the author finds those of 'Besredka, Boquet-N~gre and KlopstockNeuherg to be the most satisfactory. T h e following chapters then deal with the diagnostic value of the reaction in the different localizations of tuberculosis and with its specificity. Wlfilst stressing the usually good agreement between the clinical findings and the result of the reaction, the author makes clear its limitations, such as its occasional failure in certain cases of tuberculosis, its non-specificity in syphilis and its lack of prognostic value. As a supplement to t h e complement fixation reaction the author recommends the resorcine flocculation reaction of Vernes, about which a chapter is included, dealing with its technique and its results. An account of the results obtained iwith the complement fixation reaction in animal tuberculosis, on which the author has contributed much original research, will be of special interest to the veterinary surgeon. Taken altogether the evidence brought forward in this monograph confirms the author's view that the tuberculous complement fixation reaction is a valuable supplement to the clinical methods in the diagnosis of tuberculosis.
This monograph of 2I 4 pages is a clinical, radiological and pathological study of fibrosis in the coal-miners of the Departements de la Loire and du Nord. T h e authors stress the importance of a careful industrial history and the role of rock-drilling in the aetiology of the pneumoconiosis. Personal idiosyncrasy to silica dust and the part played in the disease by infections, particularly tuberculosis, are discussed and tables are given comparing the incidence of tuberculosis in the general and mining populations of a number of districts. T h e authors have standardized their clinical, pathological and radiological technique and used these standards throughout the investigation. The cases are illustrated by series of radiographs, many taken at various periods during the progress of the disease, and the postmortem appearances compared with the radiographical. Photomicrographs under polarized light show the accumulation of doubly refractile particles of dust in fibrosed areas and in the perivascular tissue. T h e aetiology, mode of action of dust, diagnosis and prophylaxis are briefly discussed. T h e book, illustrated by I34 radiographs and 6I photographs and photomicrographs all of which are excellent, can be thoroughly recommended as a useful addition to the literature of silicosis in coal-miners. DIE P L E U R I T I S . Die verschiedenen Formen--ihre Entstehung Erkennung und Behandlung. By PROFESSOR B. HANNS ALEXA~qDER. Leipzig. Georg Thieme. pp. 4 o, Illustrated. RM. 2.90. In this work on the different forms of pleurisy including their origin, recognition and treatment, which forms part of the series entitled 'Praktische TuberkuloseBfichcrci', a supplement of the journal Deutsdzes Tuberkulose-Blatt, Professor Alexander, the director of the Deutsches Haus
LA FIBROSE P U L M O N A I R E DES M I N E U R S . By L. CROIZIER, E. MARTIn and A. POLICARD. Paris. Masson et Cie. pp. 2i 4. Illustrated. Price I65 fr.
In view of the extensive literature on tile tuberculous complement fixation reaction accumulated during the last twenty years and the progress made in the study of the nature of this reaction, a review of the whole problem is welcome. Dealing first with the technique of the reaction the author gives a detailed description of the preparation of the various antigens recommended and then reviews the different methods for examining complement fixing antibodies. A short discussion on the chemical nature of the antigen follows, in which the non-lipoid antigen which has lately been the object of ' much investigation could perhaps have been treated more fully. Reviewing the results reported to have been obtained with the various antigens the author finds those of 'Besredka, Boquet-N~gre and KlopstockNeuherg to be the most satisfactory. T h e following chapters then deal with the diagnostic value of the reaction in the different localizations of tuberculosis and with its specificity. Wlfilst stressing the usually good agreement between the clinical findings and the result of the reaction, the author makes clear its limitations, such as its occasional failure in certain cases of tuberculosis, its non-specificity in syphilis and its lack of prognostic value. As a supplement to t h e complement fixation reaction the author recommends the resorcine flocculation reaction of Vernes, about which a chapter is included, dealing with its technique and its results. An account of the results obtained iwith the complement fixation reaction in animal tuberculosis, on which the author has contributed much original research, will be of special interest to the veterinary surgeon. Taken altogether the evidence brought forward in this monograph confirms the author's view that the tuberculous complement fixation reaction is a valuable supplement to the clinical methods in the diagnosis of tuberculosis.
This monograph of 2I 4 pages is a clinical, radiological and pathological study of fibrosis in the coal-miners of the Departements de la Loire and du Nord. T h e authors stress the importance of a careful industrial history and the role of rock-drilling in the aetiology of the pneumoconiosis. Personal idiosyncrasy to silica dust and the part played in the disease by infections, particularly tuberculosis, are discussed and tables are given comparing the incidence of tuberculosis in the general and mining populations of a number of districts. T h e authors have standardized their clinical, pathological and radiological technique and used these standards throughout the investigation. The cases are illustrated by series of radiographs, many taken at various periods during the progress of the disease, and the postmortem appearances compared with the radiographical. Photomicrographs under polarized light show the accumulation of doubly refractile particles of dust in fibrosed areas and in the perivascular tissue. T h e aetiology, mode of action of dust, diagnosis and prophylaxis are briefly discussed. T h e book, illustrated by I34 radiographs and 6I photographs and photomicrographs all of which are excellent, can be thoroughly recommended as a useful addition to the literature of silicosis in coal-miners. DIE P L E U R I T I S . Die verschiedenen Formen--ihre Entstehung Erkennung und Behandlung. By PROFESSOR B. HANNS ALEXA~qDER. Leipzig. Georg Thieme. pp. 4 o, Illustrated. RM. 2.90. In this work on the different forms of pleurisy including their origin, recognition and treatment, which forms part of the series entitled 'Praktische TuberkuloseBfichcrci', a supplement of the journal Deutsdzes Tuberkulose-Blatt, Professor Alexander, the director of the Deutsches Haus