797
Summary
Total-blood-sugar and blood-glucose levels were estimated in eleven infants after lactose-containing feeds, and in one infant after a galactose feed. Three of the infants were normal full-term babies, five were premature, one was jaundiced, two had diarrhcea, and one had eczema. They were aged 1 day to 4 months. After the feeds several samples of blood showed saccharoid material, amounting to 20-30 mg. per 100 ml., as deduced from differences in the two methods of analysis. Galactose was not identified in any of the blood specimens examined by paper chromatography, and it was therefore concluded that this sugar was not present in amounts greater than 10-20 mg. per 100 ml., which could not account for the whole saccharoid function. These findings differ from those of previous workers who reported a high concentration of galactose in the blood of infants after the ingestion of lactose. Fasting hypoglycaemia was found in all the newborn
babies examined, and two had no detectable sugar in their blood. None of these babies showed any symptoms attributable to the hypoglyctn-iia. We wish to thank Dr. H. Medovy, Dr. S. Israels, Dr. K. C. Finkel, and Miss B. Gourley for their advice and criticism, and several other physicians for permission to study their patients. This work was supported by a Mead Johnson grant for pxdiatric research, administered by the American Academy of Pediatrics. REFERENCES
Dormandy, T. L., Leak, D., Grant, M. (1959) Lancet, ii, 269. Farquhar, J. W. (1954) Arch. Dis. Childh. 29, 519. Greenberg, R. E., Gardner, L. I. (1959) Amer. J. Dis. Child. 98, 671. Hartmann, A. F., Jaudon, J. C. (1937) J. Pediat. 11, 1. Grunwaldt, E., James, D. H. (1953) ibid. 43, 1. McCoy, E. E., Swarm, P. A., Nakasato, D. I. (1954) ibid. 44, 499. Haworth, J. C. (1960) Arch. Dis. Childh. (in the press). MacDonald, M. S. (1957) ibid. 32, 417. Huggett, A. St. G., Nixon, D. A. (1957) Lancet, ii, 368. King, E. J. (1951) Micro-analysis in Medical Biochemistry; p. 23. London. Middleton, J. E. (1959) Brit. med. J. i, 824. Miller, H. C., Ross, R. A. (1940) J. Pediat. 16, 473. Norval, M. A. (1950) ibid. 36, 177. Kennedy, R. L. J., Berkson, J. (1949) ibid. 34, 342. Sadoff, R. L., Ulstrom, R. A. (1959) Univ. Minn. med. Bull. 30, 387. Trevelyan, W. E., Procter, D. P., Harrison, J. S. (1950) Nature, Lond. 166, -
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Williams, R. (1954) J. med. Lab. Technol. 12,
43.
Reviews of Books
New Inventions LIMB SUSPENSION IN VARICOSE-VEIN SURGERY THIS method has been in use for some 10 years, but does not seem to be widely known. The advantages are that blood-loss is reduced almost to nothing, hsematomas do not form, and access to the limb is so good that the seldom needs to patient be turned during operation. Skin preparation, towelling, and bandaging are also easier as no assistant is needed to hold up the leg. ’
Prematurity Diagnosis, Care and Disorders of the Premature Infant. BERYL CORNER, M.D., F.R.C.P., consultant paediatrician. United Bristol Hospitals, and lecturer in child health, University of Bristol. London:Cassell. 1960. Pp. 600. 105s. THIS fine new book on the important social, economic, and medical problem of prematurity is a tour-de-force by one very well qualified to write it. It deals with all aspects of prematurity and caters for all concerned-doctors, researchworkers, students, midwives, nurses, and health visitors-and Dr. Corner rightly emphasises the importance of understanding the anatomy and physiology of such immature creatures by including an authoritative section of 130 pages on these aspects. There follows an excellent section of equal length on the care of the premature infant, the fruit of long practical experience by the pioneer of the fully comprehensive service for the care of all premature babies born in the Bristol area. The section on the disorders of the premature infant is also comprehensive and much of it also applies to the mature newborn infant, but it is salutary to consider all the ills of premature babies in the light of their frailty and special circumstances. This section includes a valuable chapter on disorders of the eyes by Mr. C. A. Brown, an ophthalmologist with much experience of the newborn. The final section is concerned with prognosis, both immediate and remote, and this includes a good account of the pathology of the premature infant by Dr. Norman J. Brown, who has collaborated with Dr. Corner for many years. There is an ample well-chosen bibliography and 139 good illustrations. This balanced, pleasantly written book is certainly an essential for all concerned with the care of premature babies. Pediatric Dermatology HENRY H. PERLMAN, M.D., PHAR.D., clinical professor of poediatrics, Jefferson Medical College, Philadelphia. Chicago : Year
Technique.-With the table low the limb is suspended almosi vertically from a mobile stand by a webbing sling under the heel (see figure). The table is then raised to a convenient height, which opens the groin. When the groin dissection i! complete, and the stripper has been inserted, the table Ü lowered. The vein is then stripped, and other interruptioru are performed, with very little bleeding. The incisions ar( closed, and a 6-in. crepe bandage is applied. The illustration
was
tion, Guy’s Hospital.
drawn
by the department of medical illustraREX LAWRIE
Guy’s Hospital,
London,
S.E.1
M.D.,
M.S.
Lond., F.R.C.S.,
M.R.C.P
Book Publishers. London: Interscience Publishers. 1960. 135s.
Pp. 477.
INCREASING demand for specialised textbooks has stimulated Dr. Perlman to write this excellent one designed for paediatricians, general practitioners, teachers, and students. It had its beginning as long ago as 1928 in a series of lectures and demonstrations to graduate students at the Children’s Hospital in Philadelphia. The general reader will be glad that histopathological descriptions are kept to a minimum and he will welcome the detailed attention to differential diagnosis. A praiseworthy departure from textbook practice is the amount of space50 pages-allotted to the principles of treatment, remedial