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MP-07.11: Characteristics of voiding dysfunction in women with lower urinary tract disorders
MODERATED POSTER SESSIONS
Abstract Withdrawn
Conclusions: In a voiding phase, women with SUI demonstrated a low-pressure with a high-flow, indicating that the degree of BOO was less in comparison to that of women who were supposed to be urologically normal. On the other hand, the women with cystocele demonstrated a lowpressure with a low-flow, suggesting a higher prevalence of detrusor underactivity in these patients.
MP-07.11 Characteristics of voiding dysfunction in women with lower urinary tract disorders Seki N1, Takei M2, Yamaguchi A2, Naito S1 1 Department of Urology, Graduate School of Medical Sciences, Kyushu University; 2Department of Urology, Harasanshin Hospital, Fukuoka, Japan Objectives: SUI and cystocele are representative disorders associated with lower urinary tract dysfunction in women. In the current study, we attempted to elucidate the urodynamic characteristics of lower urinary tract focusing on the degree of detrusor contractility and BOO in adult women with genuine SUI or women with severe cystocele, by comparing that of strictly selected cohorts of symptom-free women who were supposed to have urological normal voiding. Materials & Methods: We prospectively evaluated neurologically intact 56 women with genuine SUI and 58 women with highgrade cystocele with no SUI. All patients underwent evaluation in which their severity of LUTS by questionnaires and full urodynamics data were determined. Parameters quantifying a degree of BOO and detrusor contractility were compared with the results obtained from 78 symptoms free urological normal women over the same period. Results: The patients with cystocele had a consistently lower Qmax with a significant lower WFmax than did the controls or the patients with SUI. The patients with SUI had a significantly higher Qmax than did the controls. The detrusor pressure during micturition was significantly lower both in the cystocele and SUI cohorts, in comparison to that of the controls (Table).
Table.
MP-07.12 Sexual dysfunction in women with newly diagnosed multiple sclerosis Skriapas K1, Konstantinidis C2, Tzortzis V1, Hadjigeorgiou G3, Samarinas M1, Aggelakis K3, Poulakis V4, Melekos M1 1 University of Thessaly, School of Medicine, Urology Department, Larissa, Greece; 2National Institute of Rehabilitation, Urology Department, Athens Greece; 3 University of Thessaly, School of Medicine, Neurology Department, Larissa Greece; 4Medical Center of Athens, Urology Department, Athens, Greece Introduction: The aim of the study was to evaluate female sexuality in a selective population of newly diagnosed Multiple Sclerosis (MS) women’s and to compare these findings with those from a control group of healthy female volunteers. Methods: In this clinic-based study, 63 newly diagnosed consecutive women affected by definite MS were admitted. Disability and psychological functioning were evaluated with the Expanded Disability Status Scale (EDSS) and Beck’s Depression Inventory (BDI) respectively. Sexual function was evaluated with the Female Sexual Function Index (FSFI). MS patients were matched and compared with a group of 61 female healthy volunteers with the same baseline characteristics.
Results: All the evaluated patients were ambulant with no major neurological impairment (mean EDSS score 2.5, range 0-3.5). None of the patients were considered clinically depressed, but some of them were sad or worried. According to the sexual history and FSFI scores, sexual dysfunction (SD) was diagnosed in 41 (65.1%) out of the 63 patients and in 9 (14.7 %) out of the 61 health females. Orgasm and Lubrication problems were higher in the MS patients but with no significantly difference (p⬍0.08). Conclusion: Sexual dysfunction is a highly prevalent condition in MS patients. The age at onset of the disease and other concomitant disorders may have a great impact on SD. MP-07.13 Transobturator suburethral tape ARIS in the treatment of stress urinary incontinence: one year evaluation Delmas V1, Ballanger P2, Grise P3, Ortuno C4 1 Urology, Bichat hospital, Paris, France; 2 Urology, Pellegrin Tondu hospital, Bordeaux, France; 3Urology, Charles Nicolle hospital, Rouen, France; 4Porge`s-Coloplast, Le Plessis Robinson, France Introduction: The transobturator suburethral tapes are one of the new way of treatment of female stress urinary incontinence. They have to prove with a follow up their efficacy and their safety. The aim of this study is to evaluate the functional and anatomical results after one year of the ARIS suburethral tape in a prospective multicentric study. Methods: A new polypropilene tape (ARIS by Porge`s-Coloplast) has been proposed since 2005. A group of 13 urologists have accepted to include their pa-
MP-07.11
MCC (ml) DO (%) F-Qmax (ml/sec) Co. F-Qmax (ml/sec) V.V. (ml) PVR (ml) PFS-Qmax (ml/sec) pdet.Qmax (cmH2O) pdet.max (cmH2O) URF BCI WFmax (W/m2)
Control (78) 344 (108) 0 27.7 (9.3) 1.71 (0.43) 278 (122) 0 (0, 8) 25.3 (10.5) 30.3 (15.6) 38.4 (18.8) 0.06 (0.03, 0.09) 153 (52) 12.4 (7.2)
SUI (56) 370 (111) 8.3 (4/56) 31.3 (13.0) 1.94 (0.80) 266 (88) 5 (3, 13)* 26.7 (12.9) 15.9 (8.3)* 21.1 (10.7)* 0.02 (0.01, 0.04)* 149 (41) 11.6 (3.2)
Cystocele (58) 368 (109) 0 20.9 (9.8)*# 1.28 (0.44)*# 281 (114) 12 (0, 42)* 19.5 (8.6)*# 20.7 (12.6)* 26.5 (14.0)* 0.07 (0.03, 0.12)# 112 (42)*# 8.7 (5.0)*#
Mean (SD); Median (25%, 75%). * P⬍0.05 (vs Control); # P⬍0.05 (vs SUI); ** P⬍0.05 (vs Pre-operative). DO: Detrusor overactivity; Co. F-Qmax: Corrected F-Qmax; V.V.: Voided volume; URF: Urethral resistant factor; BCI: Bladder contractility index; MCC: Maximum cystometric capacity; F-Qmax: Qmax in free-flow test.
74
UROLOGY 70 (Supplment 3A), September 2007
Abstract Withdrawn
Conclusions: In a voiding phase, women with SUI demonstrated a low-pressure with a high-flow, indicating that the degree of BOO was less in comparison to that of women who were supposed to be urologically normal. On the other hand, the women with cystocele demonstrated a lowpressure with a low-flow, suggesting a higher prevalence of detrusor underactivity in these patients.
MP-07.11 Characteristics of voiding dysfunction in women with lower urinary tract disorders Seki N1, Takei M2, Yamaguchi A2, Naito S1 1 Department of Urology, Graduate School of Medical Sciences, Kyushu University; 2Department of Urology, Harasanshin Hospital, Fukuoka, Japan Objectives: SUI and cystocele are representative disorders associated with lower urinary tract dysfunction in women. In the current study, we attempted to elucidate the urodynamic characteristics of lower urinary tract focusing on the degree of detrusor contractility and BOO in adult women with genuine SUI or women with severe cystocele, by comparing that of strictly selected cohorts of symptom-free women who were supposed to have urological normal voiding. Materials & Methods: We prospectively evaluated neurologically intact 56 women with genuine SUI and 58 women with highgrade cystocele with no SUI. All patients underwent evaluation in which their severity of LUTS by questionnaires and full urodynamics data were determined. Parameters quantifying a degree of BOO and detrusor contractility were compared with the results obtained from 78 symptoms free urological normal women over the same period. Results: The patients with cystocele had a consistently lower Qmax with a significant lower WFmax than did the controls or the patients with SUI. The patients with SUI had a significantly higher Qmax than did the controls. The detrusor pressure during micturition was significantly lower both in the cystocele and SUI cohorts, in comparison to that of the controls (Table).
Table.
MP-07.12 Sexual dysfunction in women with newly diagnosed multiple sclerosis Skriapas K1, Konstantinidis C2, Tzortzis V1, Hadjigeorgiou G3, Samarinas M1, Aggelakis K3, Poulakis V4, Melekos M1 1 University of Thessaly, School of Medicine, Urology Department, Larissa, Greece; 2National Institute of Rehabilitation, Urology Department, Athens Greece; 3 University of Thessaly, School of Medicine, Neurology Department, Larissa Greece; 4Medical Center of Athens, Urology Department, Athens, Greece Introduction: The aim of the study was to evaluate female sexuality in a selective population of newly diagnosed Multiple Sclerosis (MS) women’s and to compare these findings with those from a control group of healthy female volunteers. Methods: In this clinic-based study, 63 newly diagnosed consecutive women affected by definite MS were admitted. Disability and psychological functioning were evaluated with the Expanded Disability Status Scale (EDSS) and Beck’s Depression Inventory (BDI) respectively. Sexual function was evaluated with the Female Sexual Function Index (FSFI). MS patients were matched and compared with a group of 61 female healthy volunteers with the same baseline characteristics.
Results: All the evaluated patients were ambulant with no major neurological impairment (mean EDSS score 2.5, range 0-3.5). None of the patients were considered clinically depressed, but some of them were sad or worried. According to the sexual history and FSFI scores, sexual dysfunction (SD) was diagnosed in 41 (65.1%) out of the 63 patients and in 9 (14.7 %) out of the 61 health females. Orgasm and Lubrication problems were higher in the MS patients but with no significantly difference (p⬍0.08). Conclusion: Sexual dysfunction is a highly prevalent condition in MS patients. The age at onset of the disease and other concomitant disorders may have a great impact on SD. MP-07.13 Transobturator suburethral tape ARIS in the treatment of stress urinary incontinence: one year evaluation Delmas V1, Ballanger P2, Grise P3, Ortuno C4 1 Urology, Bichat hospital, Paris, France; 2 Urology, Pellegrin Tondu hospital, Bordeaux, France; 3Urology, Charles Nicolle hospital, Rouen, France; 4Porge`s-Coloplast, Le Plessis Robinson, France Introduction: The transobturator suburethral tapes are one of the new way of treatment of female stress urinary incontinence. They have to prove with a follow up their efficacy and their safety. The aim of this study is to evaluate the functional and anatomical results after one year of the ARIS suburethral tape in a prospective multicentric study. Methods: A new polypropilene tape (ARIS by Porge`s-Coloplast) has been proposed since 2005. A group of 13 urologists have accepted to include their pa-
MP-07.11
MCC (ml) DO (%) F-Qmax (ml/sec) Co. F-Qmax (ml/sec) V.V. (ml) PVR (ml) PFS-Qmax (ml/sec) pdet.Qmax (cmH2O) pdet.max (cmH2O) URF BCI WFmax (W/m2)
Control (78) 344 (108) 0 27.7 (9.3) 1.71 (0.43) 278 (122) 0 (0, 8) 25.3 (10.5) 30.3 (15.6) 38.4 (18.8) 0.06 (0.03, 0.09) 153 (52) 12.4 (7.2)
SUI (56) 370 (111) 8.3 (4/56) 31.3 (13.0) 1.94 (0.80) 266 (88) 5 (3, 13)* 26.7 (12.9) 15.9 (8.3)* 21.1 (10.7)* 0.02 (0.01, 0.04)* 149 (41) 11.6 (3.2)
Cystocele (58) 368 (109) 0 20.9 (9.8)*# 1.28 (0.44)*# 281 (114) 12 (0, 42)* 19.5 (8.6)*# 20.7 (12.6)* 26.5 (14.0)* 0.07 (0.03, 0.12)# 112 (42)*# 8.7 (5.0)*#
Mean (SD); Median (25%, 75%). * P⬍0.05 (vs Control); # P⬍0.05 (vs SUI); ** P⬍0.05 (vs Pre-operative). DO: Detrusor overactivity; Co. F-Qmax: Corrected F-Qmax; V.V.: Voided volume; URF: Urethral resistant factor; BCI: Bladder contractility index; MCC: Maximum cystometric capacity; F-Qmax: Qmax in free-flow test.
74
UROLOGY 70 (Supplment 3A), September 2007