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Nicotinic ACID
RIEMS VACCINE IN F.'AND-M. DISEASE
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properties recall protozoal infections. Also many virus diseases exhibit the carrier conditions, whereby the host may carry the infection for long periods without showing any signs of disease, another feature more commonly associated with protozoal than bacterial infections. I have no intention, however, of supporting a protozoal as against a bacterial nature for viruses, except to point out the necessity of regarding these organisms as not yet sufficiently differentiated to show the characteristics generally associated with one or othe r of these groups of living beings. Logically, one is bound to admit the existence of stages in the evolution of living organisms from non-living matter, but apart from their excessively small size, most of the viruses that have been sufficiently studied seem to have already attained the more important characteristics of life.
NICOTINIC ACID NICOTINIC acid, recently isolated from liver, is reported to be highly effective, in doses of 1.5 mg. per kilogram of body weight, in curing blacktongue in dogs and "harmless, whether administered orally, intramuscularly or intravenously" (Margolis, Margolis and Smith, quoted by Smith and Coworkers, f. A. M. A ., 109 (25), 1937, 2054-55 ). Smith and co-workers report successful treatment of a case of human pellagra with nicotinic acid. Doses of 60 mg. were given daily for 12 days. Nicotinic acid is very cheap and this treatment costs less than 10 cents. " If subsequent investigations prove that nicotinic acid is the P-P factor of Goldberger ... it is possible that it could be mixed with table salt and sold in areas where pellagra is endemic, similarly to the distribution of 'iodised' salt in districts in which goitre is prevalent."-N. Amer. Veter., June, 1938.
FURTHER TESTS WITH THE RIEMS VACCINE AGAINST F... AND ..M. DISEASE * By DR. HAAN, of Frankfort, and DR. MAAS, of Soldin 1. RIEM S vaccine in general inoculation is harmless, it causes no infection. 2. Subsequent outbreaks after cattle virus vaccination occurred in 8 days and after culture virus in 15 days. In ring inoculation in disease areas 35 per cent. in the worst outbreaks, but in the unaffected areas only 3 per cent.
* B.T.W.,
March 17, No. 11.
325
properties recall protozoal infections. Also many virus diseases exhibit the carrier conditions, whereby the host may carry the infection for long periods without showing any signs of disease, another feature more commonly associated with protozoal than bacterial infections. I have no intention, however, of supporting a protozoal as against a bacterial nature for viruses, except to point out the necessity of regarding these organisms as not yet sufficiently differentiated to show the characteristics generally associated with one or othe r of these groups of living beings. Logically, one is bound to admit the existence of stages in the evolution of living organisms from non-living matter, but apart from their excessively small size, most of the viruses that have been sufficiently studied seem to have already attained the more important characteristics of life.
NICOTINIC ACID NICOTINIC acid, recently isolated from liver, is reported to be highly effective, in doses of 1.5 mg. per kilogram of body weight, in curing blacktongue in dogs and "harmless, whether administered orally, intramuscularly or intravenously" (Margolis, Margolis and Smith, quoted by Smith and Coworkers, f. A. M. A ., 109 (25), 1937, 2054-55 ). Smith and co-workers report successful treatment of a case of human pellagra with nicotinic acid. Doses of 60 mg. were given daily for 12 days. Nicotinic acid is very cheap and this treatment costs less than 10 cents. " If subsequent investigations prove that nicotinic acid is the P-P factor of Goldberger ... it is possible that it could be mixed with table salt and sold in areas where pellagra is endemic, similarly to the distribution of 'iodised' salt in districts in which goitre is prevalent."-N. Amer. Veter., June, 1938.
FURTHER TESTS WITH THE RIEMS VACCINE AGAINST F... AND ..M. DISEASE * By DR. HAAN, of Frankfort, and DR. MAAS, of Soldin 1. RIEM S vaccine in general inoculation is harmless, it causes no infection. 2. Subsequent outbreaks after cattle virus vaccination occurred in 8 days and after culture virus in 15 days. In ring inoculation in disease areas 35 per cent. in the worst outbreaks, but in the unaffected areas only 3 per cent.
* B.T.W.,
March 17, No. 11.