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Nlr of Pro-Cryoablation Can Predict the Prognosis of Patients with Advanced Hepatocellular Carcinoma
Annals of Oncology 25 (Supplement 5): v44–v74, 2014 doi:10.1093/annonc/mdu435.6
Oral Session (Oral presentations categorized by each organ) O1
2
5
Juan Xiu Chang, Zhen Zeng, Ying Yin Lu, Hiu Jian Qu, Lin Gui Xu, Xudong Gao, Hong Wang, Min Lou, Chunping Wang, Yongping Yang Research Center for Live Cancer Diagnosis and Therapy, The 302 hospital of PLA
abstracts
Inflammatory response is related to tumor inhibition that has been reported by researches. Neutrophils and lymphocytes ratio (NLR) is one of the evaluation indexes. NLR can reflect the whole body inflammatory response. It has been considered as one of the tumor prognostic factors. Studies in patients with lung cancer, colon cancer, gastric cancer etc. have confirmed that high NLR can reflect inflammation respond and is related to clinical staging and survival, and prognosis malignant tumor patients with
© The Author 2014. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: [email protected].
Downloaded from https://academic.oup.com/annonc/article-abstract/25/suppl_5/v45/2240289 by guest on 24 October 2019
NLR OF PRO-CRYOABLATION CAN PREDICT THE PROGNOSIS OF PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA
high NLR is poor. Researches about relation of NLR and prognosis of hepatocellular carcinoma are seldom. This study is to analy clinical material of patients of advanced hepatocellular carcinoma in hospital, and to explore the predictive valure of NLR of preoperative cryoablation for advanced hepatocelluar carcinoma. Objective: Neutrophils and lymphocytes ratio (NLR) is one of the evaluation inflammation indexes. It has been regarded as one of the prognostic factors of Hepatocellular carcinoma. This study is to explore the relationship with the prognosis of advanced Hepatocellular carcinoma with NLR of preoperative cryoablation. Methods: It is a retrospective clinical study about 150 cases with advanced hepacelluar carcinoma in our hospital in 2008-2009. We analy the NLR of preoperative cryoablation and explore the relationship between NLR and survival of patients with hepacelluar carcinoma. Results: It is found that child - pugh grading, portal vein tumor thrombus, preoperative NLR, tumor differentiation are related with survival of patients with advanced hepacelluar carcinoma through the single factor analysis. By multiariable COX survival analysis found that NLR of preoperative cryoablation, child - pugh grading, tumor differentiation are risk factors for patients with advanced hepacelluar carcinoma survival. Conclusion: NLR of preoperative cryoablation can be used to judge the prognosis of patients with advanced hepacelluar carcinoma.
Oral Session (Oral presentations categorized by each organ) O1
2
5
Juan Xiu Chang, Zhen Zeng, Ying Yin Lu, Hiu Jian Qu, Lin Gui Xu, Xudong Gao, Hong Wang, Min Lou, Chunping Wang, Yongping Yang Research Center for Live Cancer Diagnosis and Therapy, The 302 hospital of PLA
abstracts
Inflammatory response is related to tumor inhibition that has been reported by researches. Neutrophils and lymphocytes ratio (NLR) is one of the evaluation indexes. NLR can reflect the whole body inflammatory response. It has been considered as one of the tumor prognostic factors. Studies in patients with lung cancer, colon cancer, gastric cancer etc. have confirmed that high NLR can reflect inflammation respond and is related to clinical staging and survival, and prognosis malignant tumor patients with
© The Author 2014. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: [email protected].
Downloaded from https://academic.oup.com/annonc/article-abstract/25/suppl_5/v45/2240289 by guest on 24 October 2019
NLR OF PRO-CRYOABLATION CAN PREDICT THE PROGNOSIS OF PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA
high NLR is poor. Researches about relation of NLR and prognosis of hepatocellular carcinoma are seldom. This study is to analy clinical material of patients of advanced hepatocellular carcinoma in hospital, and to explore the predictive valure of NLR of preoperative cryoablation for advanced hepatocelluar carcinoma. Objective: Neutrophils and lymphocytes ratio (NLR) is one of the evaluation inflammation indexes. It has been regarded as one of the prognostic factors of Hepatocellular carcinoma. This study is to explore the relationship with the prognosis of advanced Hepatocellular carcinoma with NLR of preoperative cryoablation. Methods: It is a retrospective clinical study about 150 cases with advanced hepacelluar carcinoma in our hospital in 2008-2009. We analy the NLR of preoperative cryoablation and explore the relationship between NLR and survival of patients with hepacelluar carcinoma. Results: It is found that child - pugh grading, portal vein tumor thrombus, preoperative NLR, tumor differentiation are related with survival of patients with advanced hepacelluar carcinoma through the single factor analysis. By multiariable COX survival analysis found that NLR of preoperative cryoablation, child - pugh grading, tumor differentiation are risk factors for patients with advanced hepacelluar carcinoma survival. Conclusion: NLR of preoperative cryoablation can be used to judge the prognosis of patients with advanced hepacelluar carcinoma.