Notable Papers

NOTABLE PAPERS We are pleased to announce the following 4 clinical and 4 basic articles judged by the editors of HeartRhythm as the most notable published in 2015 for presentation at the Heart Rhythm Society Scientific Sessions in San Francisco, May 2016. CLINICAL 1. Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study): David D. McManus, MD, MSc, FHRS, Kahraman Tanriverdi, PhD, Honghuang Lin, PhD, Nada Esa, MD, Menhel Kinno, MD, Divakar Mandapati, MD, Stanley Tam, MD, MBA, Okike N. Okike, MD, Patrick T. Ellinor, MD, PhD, FHRS, John F. Keaney Jr., MD, J. Kevin Donahue, MD, FHRS, Emelia J. Benjamin, MD, MSc, Jane E. Freedman, MD. Published January 2015, Volume 12, Issue 1, Pages 3–10. 2. Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study: Roderick Tung, MD, FHRS, Marmar Vaseghi, MD, MS, FHRS, David S. Frankel, MD, FHRS, Pasquale Vergara, MD, PhD, Luigi Di Biase, MD, PhD, FHRS, Koichi Nagashima, MD, PhD, Ricky Yu, MD, Sitaram Vangala, MS, Chi-Hong Tseng, PhD, Eue-Keun Choi, MD, PhD, Shaan Khurshid, MD, Mehul Patel, MD, Nilesh Mathuria, MD, Shiro Nakahara, MD, PhD, Wendy S. Tzou, MD, FHRS, William H. Sauer, MD, FHRS, Kairav Vakil, MD, Usha Tedrow, MS, MD, FHRS, J. David Burkhardt, MD, FACC, FHRS, Venkatakrishna N. Tholakanahalli, MD, FHRS, Anastasios Saliaris, MD, Timm Dickfeld, MD, PhD, FHRS, J. Peter Weiss, MD, T. Jared Bunch, MD, Madhu Reddy, MD, FHRS, Arun Kanmanthareddy, David J. Callans, MD, FHRS, Dhanunjaya Lakkireddy, MD, FHRS, Andrea Natale, MD, FHRS, Francis Marchlinski, MD, FHRS, William G. Stevenson, MD, FHRS, Paolo Della Bella, MD, Kalyanam Shivkumar, MD, PhD, FHRS. Published September 2015, Volume 12, Issue 9, Pages 1997–2007. 3. Multipoint pacing by a left ventricular quadripolar lead improves the acute hemodynamic response to CRT compared with conventional biventricular pacing at any site: Francesco Zanon, MD, FESC, FHRS, Enrico Baracca, MD, Gianni Pastore, MD, Lina Marcantoni, MD, Chiara Fraccaro, MD, PhD, Daniela Lanza, MD, Claudio Picariello, MD, Silvio Aggio, MD, Loris Roncon, MD, Fabio Dell’Avvocata, MD, GianLuca Rigatelli, MD, Domenico Pacetta, Eng, Franco Noventa, MD, Frits W. Prinzen, PhD. Published May 2015, Volume 12, Issue 5, Pages 975–981. 4. His-bundle pacing versus biventricular pacing in cardiac resynchronization therapy patients: A crossover design comparison: Daniel L. Lustgarten, MD, PhD, FHRS, Eric M. Crespo, MD, MPH, FHRS, Irina Arkhipova-Jenkins, MD, Robert Lobel, MD, Joseph Winget, MD, Jodi Koehler, MS, Evan Liberman, BS, Todd Sheldon, MS. Published July 2015, Volume 12, Issue 7, Pages 1548–1557. BASIC 1. The cardiomyocyte molecular clock regulates the circadian expression of Kcnh2 and contributes to ventricular repolarization: Elizabeth A. Schroder, PhD, Don E. Burgess, PhD, Xiping Zhang, PhD, Mellani Lefta, PhD, MD, Jennifer L. Smith, BS, Abhijit Patwardhan, PhD, Daniel C. Bartos, PhD, Claude S. Elayi, MD, Karyn A. Esser, PhD, Brian P. Delisle, PhD. Published June 2015, Volume 12, Issue 6, Pages 1306–1314. 2. Pulmonary vein triggers play an important role in the initiation of atrial flutter: Initial results from the prospective randomized Atrial Fibrillation Ablation in Atrial Flutter (Triple A) trial: Ralph Schneider, MD, Joerg Lauschke, MD, Tina Tischer, MD, Cindy Schneider, MD, Wolfgang Voss, MD, Felix Moehlenkamp, Aenne Glass, Doreen Diedrich, Dietmar Bänsch, PhD. Published May 2015, Volume 12, Issue 5, Pages 865–871. 3. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current: Ludovic Gillet, PhD, Jean-Sébastien Rougier, PhD, Diana Shy, MSc, Stephan Sonntag, PhD, Nathalie Mougenot, PhD, Maria Essers, BSc, Doron Shmerling, PhD, Elise Balse, PhD, Stéphane N. Hatem, MD, PhD, Hugues Abriel, MD, PhD. Published January 2015, Volume 12, Issue 1, Pages 181–192. 4. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation: Eric Chong, MD, Shih-Lin Chang, MD, PhD, Ya-Wen Hsiao, PhD, Rahul Singhal, MD, Shuen-Hsin Liu, MD, Trung Leha, MD, Wen-Yu Lin, MD, Chiao-Po Hsu, MD, PhD, Yao-Chang Chen, MSc, Yi-Jen Chen, MD, PhD, Tsu-Juey Wu, MD, PhD, Satoshi Higa, MD, PhD, Shih-Ann Chen, MD. Published May 2015, Volume 12, Issue 5, Pages 1046–1056.