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OP-191 Mental and Physical Quality of Life in Patients with Normal Coronary Artery
MARCH 26e29, 2015
O R A L A B S T R A C T S
to > 2.25 mm diameter epicardial arteries in these studies. However, Syntax score takes into account the > 50% stenosis and > 1.5 mm diameter artery. In our study, we aimed to compare Syntax scores that were obtained from > 50% lesions and > 1.5 mm diameter artery and 70% lesions and > 2 mm diameter artery for death. Methods: In our study, 536 patients with unstable angina and non ST elevation MI and performed coronary angiography between May to November 2012. From all patients four different syntax score were calculated such as vessel diameter > 1.5 mm or > 2 mm, and the degree of stenosis > 50% or > 70%. Results: All patients were followed for a year, and 52 patients died (9.7%). Clinical characteristics of death and non-death groups like that age, sex, diabetes mellitus, hypertension, dyslipidemia, smoking, chronic kidney disease, Killip > 1, SBP, DBP, heart rate and LV- EF were similar with alive group. Hovewer SVO history and history of less aspirin, beta-blocker and statin use were higher in death group. Similarly, in the group who died WBC, platelet count and CRP were higher, hemoglobin and albumin were lower. Finally, all syntax scores was found significantly higher in the death group. In the comparative ROC curve analysis, none of the syntax scores was not superior to each other to predict death. Conclusion: In our study, we showed that four different syntax score which were calculated in coronary artery disease were not releated with death in one year and these four different syntax score were not superior to each other.
Table Parameters
Control group (n¼53)
Study group (n¼53)
P value
Age(year Glucose (mg/dl) Blood urea nitrogen(mg/dl) Kreatinine(mg/dl) Total cholesterol(mg/dl) Triglyceride(mg/dl) Low density lipoprotein (LDL)(mg//dl) High density lipoprotein (HDL)(mg/dl) Hemoglobin(g/dl) WBC(m3/dl) Neutrophil(m3/dl) Platelets(K/m3) Lymphocytes(m3/dl) platelet distrubition width ratio N/L ratio P/L ratio lym/pdw Platecrit Mean platelet volume RDW(%)
60,9412,32 121,7049,57 36,3213,88 1,070,30 178,6739,82 165,3583,57 101,0631,44
62,6813,16 132,0663,14 36,6015,60 1,100,27 180,7439,43 190,38103,93 104,1032,87
0,385 0,695 0,877 0,604 0,851 0,245 0,636
43,3210,31
41,768,18
0,404
13,671,97 6,4191,882 3,7991,422 235.18963.833 1,9520,637 16,212,32
14,051,81 7,4872,760 4,5822,218 224.05769.664 1,9990,962 16,96,52
0,315 0,02 0,049 0,393 0,977 0,862
2,060,78 131,2750,01 0,120,04 0,210,05 90,84 14,792,09
2,671,72 128,4255,26 0,130,07 0,542,5 8,841,07 14,322,07
0,054 0,672 0,721 0,127 0,399 0,240
- OP-190 Stent Restenosis and Inflammatory Markers. Cengiz Ozturk1, Ahmet Ozturk4, Mustafa Aparci3, Sevket Balta2, Mustafa Demir1, Ali Osman Yildirim1. 1 Department of Cardiology, Gulhane Medical Faculty, Ankara, Turkey; 2Department of Cardiology, Eskisehir Military Hospital, Eskisehir, Turkey; 3Department of Cardiology, Kasımpasa Military Hospital, Istanbul, Turkey; 4 Department of Geriatric Medicine, Gulhane Medical Faculty, Ankara, Turkey. Background: Inflammation markers may play a part in the pathogenesis of atherosclerosis and inflammatory reaction may play a role instent restenosis (ISR) after stent implantation. The aim of the our study was to investigate the predictive value of some inflammatory markers on development of in-stent restenosis in patients undergoing stent implantation. Methods: Patients presenting with angiographically documented ISR (diameter stenosis 50% by visual estimation) were included as a study group(53 subjects) and the patients presenting with angiographically documented no ISR (diameter stenosis < 50% by visual estimation) as a control group(53 subjects). There were 15/9 females/males in control group and 38/44 females/males in study group. There were 13 patients witn diabetes mellitus in control group and 16 patients in study group. The whole groups were compared with age, lipid profiles and fasting levels of glucose. Also, hematologic parameters were measured as part of the automated complete blood count. Results: There were no statistically significant differences in baseline charecteristics between two groups. Platelet-lymphocyte ratio (PLR), lymphocyte count, lymphocyte-platelet distrubition width ratio (LPR) were not significantly higher in patients with study group compared with those of controls. But, white blood counts, neutrophil counts and neutrophil and lymphocyte ratio(N/L ratio) were significantly higher in patients with study group compared with those of controls (Table-1). Conclusion: We believe that increased some inflammatory markers white blood counts, neutrophil counts may play a role in the pathogenesis of ISR based on atherosclerosis.
Coronary Artery Disease: Implications of Prevention and Early Diagnosis Sunday, March 29, 2015 08:30 AM w 10:00 AM, Hall 9 (Abstract nos. OP-191 w OP-197) - OP-191 Mental and Physical Quality of Life in Patients with Normal Coronary Artery. Ebru Altintas1, Fatma Yigit2. 1 Department of Psychiatry, Baskent University Medical Faculty Adana Teaching and Research Center, Adana; Turkey; 2Department of Cardiology, Baskent University Medical Faculty Adana Teaching and Research Center, Adana; Turkey. Background: Ten to thirty percent of angina like chest pain patients appears to have normal coronary arteries. Depression and anxiety disorders are most common mental disorders that accompanied to chest pain with normal coronary arteries patients. It is known that mental disorders and psychosocial factors are important in occurrence of angina like chest pain and sometimes in making repetitive coronary angiography. The aim of this study was to assess the mental and physical quality of life and psychiatric co morbidities in patient angina like chest pain with normal coronary angiography.
S86 The American Journal of Cardiologyâ MARCH 26e29, 2015 11th INTERNATIONAL CONGRESS OF UPDATE IN CARDIOLOGY AND CARDIOVASCULAR SURGERY ABSTRACTS / Oral
MARCH 26e29, 2015 Table Comparison of the groups according to socio-demographic characteristics, and anxiety, depression, and SF-36 quality of life scales score
Age Education Beck Depression Inventory Beck Anxiety Inventory Physical Functioning Physical Role Limitation Bodily Pain General Health Energy Social Functioning Emotional Role Limitation Mental Health Physical Quality of Life Mental Quality of Life
NCA (n¼87) Median (Min-Max)
CAD (n¼31) Median (Min-Max)
p
51(30-72) 5(5-15) 17(3-40) 24(5-50) 25(11-30) 4(4-8) 6.1(3-11) 12.5(5-22) 10(5-23) 7(3-10) 4(3-6) 14(7-28) 47(29-69) 35(19-63)
60(43-81) 5(5-15) 16(5-36) 17(5-32) 23(14-30) 4(4-8) 7(2-11) 15(5-22) 10(5-17) 8(2-10) 6(3-6) 16(7-25) 51(32-70) 38(17-56)
0.000 0.140 0.704 0.000 0.660 0.383 0.036 0.048 0.794 0.001 0.059 0.441 0.168 0.103
p: Kruscal Wallis test (p < 0.05) pGroup1&2, pGroup1&3, pGroup2&3: Post-hoc Mann Whitney U test (p0.017 bonferoni correction) NCA: Normal coronary arteries, CAD: Coronary Artery Diseases.
Materials-Methods: Eighty-seven patients with normal coronary angiography and thirty-one patients with coronary artery disease (CAD) were included to the study. The socio-demographic characteristics, co morbid disorders, Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI), and Health Related Quality of Life (HRQoL) scale scores were compared between groups. It was estimated using the short form (SF)-36 questionnaires for total HRQoL and its two dimensions for physical and mental health. Results: There were significant differences in age, gender, employment and psychiatric disorders history in family between two groups (Table 1). Anxiety scores were significantly higher level in NCA group. No difference was found in terms of depression between the NCA and CAD groups. There were significant differences in pain, general health and social function subgroups of SF-36 in NCA group. Physical and mental health was not differences between two groups. Psychiatric co morbidities were found in 82.8 % (n¼72) of the patients with normal angiographic findings and 54.8 % (n¼ 17) of the patients with angiographic coronary disease. Discussion: Our study suggests that impairment of the mental and physical health related quality of life is similar in normal and coronary artery disease patients. We found that Normal coronary arteries patients have been feel pain and social function and general health impairment to be more than CAD patients. Psychiatric co morbidity may conclude a risk factor to impairment of quality of life in normal coronary angiography patients.
- OP-192 The Relationship of The Healthy Lifestyle Behaviors and Cardiovascular Disease Risk Factors Knowledge Level of Patients with Cardiovascular Disease and Their Relatives. Sevda Korkut Bayındır1, Gulsum Nihal Guleser1, Abdurrahman Oguzhan2. 1Faculty of Health Sciences, Erciyes University, Kayseri, Turkey; 2Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Objectives: The aim of this study is to determine relationship of cardiovascular disease risk factors knowledge level and healthy life style behaviors of patient having cardiovascular disease and their relatives. Methods: This descriptive study was conducted between January 2014 and September 2014 in 126 patients with cardiovascular disease and 109 relatives. Data were collected by the researcher using questionnaire form, Cardiovascular Disease Risk Factors Knowledge Level (CARRF-KL) scale and Healthy Living Style Behaviors Scale-II (HLSBS-II). Descriptive statistics and correlation analysis were used to evaluate the data. Results: It has been determined that the average age of patients and their relatives were 59.713.1 and 44.314.8, respectively. Total CARRF-KL and HLSBS-II score average of patients and their relatives were 18.74.1, 19.35.8 and 117.919.1, 119.723.2, respectively. There was a significant, positive correlation between CARRF-KL and HLSBS-II score patients and relatives (r¼0.551, p¼0.00), (r ¼0.398, p¼0.00), respectively. The relationship significant positive side was determined between CARRF-KL and physical activity (r¼0.381, p¼0.00), health responsibility (r¼0.484, p¼0.00), spiritual growth (r¼0.513, p¼0.00), interpersonal relationships (r¼0.321, p¼0.00), nutrition (r¼0.374, p¼0.00) and stress management (r¼0.495, p¼0.00) score patients. The relationship significant positive side was determined between CARRF-KL and physical activity (r¼0.244, p¼0.01), health responsibility (r¼0.395, p¼0.00), spiritual growth (r¼0.302, p¼0.00), interpersonal relationships (r¼0.299, p¼0.00), nutrition (r¼0.343, p¼0.00) and stress management (r¼0.324, p¼0.00) score relatives. It has been determined that as the score of CARRF-KL increases, scores of HLSBS-II, physical activity, health responsibility, spiritual growth, interpersonal relationships, nutrition, and stress management increase. Conclusion: It is recommended that nurses should be given education about cardiovascular disease risk factors, prevention and management to patients and their relatives.
- OP-193 King is Naked. Aytekin Oguz, Ozge Telci Caklili. Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine. Objective: The University Group Diabetes Program (UGDP) study showed sulfonylureas may bring more harm than benefit to diabetic patients. Since then there has been no strong evidence proving sulfonylureas can prevent mortality or major cardiovascular clinical events. But sulfonylureas are still widely used in diabetes treatment. ORIGIN study has shown that insulin treatment which was considered as the most effective and natural remedy of diabetes for many years, had no beneficial effect on mortality and complications of diabetes. Is it reasonable to treat a disease with hyperinsulinemia and insulin resistance with insulin or insulin secretagogues. In this study we aimed to evaluate the type 2 diabetes treatment perception of doctors practicing in internal medicine. Method: A survey about type 2 diabetes treatment and relevant complications were conducted on 29 doctors practicing internal medicine. A questionnaire about their choices in treatment of type 2 diabetes and how much they have faith in those drugs was filled by participants. Results: Metformin was the most preferred agent as first line therapy. Sixty-five percent of the participants found it unnecessary to use insulin for treating a disease characterized with hyperinsulinemia however 73% claimed preferring insulin treatment frequently.
The American Journal of Cardiologyâ MARCH 26e29, 2015 11th INTERNATIONAL CONGRESS OF UPDATE IN CARDIOLOGY AND CARDIOVASCULAR SURGERY ABSTRACTS / Oral
S87
O R A L A B S T R A C T S
O R A L A B S T R A C T S
to > 2.25 mm diameter epicardial arteries in these studies. However, Syntax score takes into account the > 50% stenosis and > 1.5 mm diameter artery. In our study, we aimed to compare Syntax scores that were obtained from > 50% lesions and > 1.5 mm diameter artery and 70% lesions and > 2 mm diameter artery for death. Methods: In our study, 536 patients with unstable angina and non ST elevation MI and performed coronary angiography between May to November 2012. From all patients four different syntax score were calculated such as vessel diameter > 1.5 mm or > 2 mm, and the degree of stenosis > 50% or > 70%. Results: All patients were followed for a year, and 52 patients died (9.7%). Clinical characteristics of death and non-death groups like that age, sex, diabetes mellitus, hypertension, dyslipidemia, smoking, chronic kidney disease, Killip > 1, SBP, DBP, heart rate and LV- EF were similar with alive group. Hovewer SVO history and history of less aspirin, beta-blocker and statin use were higher in death group. Similarly, in the group who died WBC, platelet count and CRP were higher, hemoglobin and albumin were lower. Finally, all syntax scores was found significantly higher in the death group. In the comparative ROC curve analysis, none of the syntax scores was not superior to each other to predict death. Conclusion: In our study, we showed that four different syntax score which were calculated in coronary artery disease were not releated with death in one year and these four different syntax score were not superior to each other.
Table Parameters
Control group (n¼53)
Study group (n¼53)
P value
Age(year Glucose (mg/dl) Blood urea nitrogen(mg/dl) Kreatinine(mg/dl) Total cholesterol(mg/dl) Triglyceride(mg/dl) Low density lipoprotein (LDL)(mg//dl) High density lipoprotein (HDL)(mg/dl) Hemoglobin(g/dl) WBC(m3/dl) Neutrophil(m3/dl) Platelets(K/m3) Lymphocytes(m3/dl) platelet distrubition width ratio N/L ratio P/L ratio lym/pdw Platecrit Mean platelet volume RDW(%)
60,9412,32 121,7049,57 36,3213,88 1,070,30 178,6739,82 165,3583,57 101,0631,44
62,6813,16 132,0663,14 36,6015,60 1,100,27 180,7439,43 190,38103,93 104,1032,87
0,385 0,695 0,877 0,604 0,851 0,245 0,636
43,3210,31
41,768,18
0,404
13,671,97 6,4191,882 3,7991,422 235.18963.833 1,9520,637 16,212,32
14,051,81 7,4872,760 4,5822,218 224.05769.664 1,9990,962 16,96,52
0,315 0,02 0,049 0,393 0,977 0,862
2,060,78 131,2750,01 0,120,04 0,210,05 90,84 14,792,09
2,671,72 128,4255,26 0,130,07 0,542,5 8,841,07 14,322,07
0,054 0,672 0,721 0,127 0,399 0,240
- OP-190 Stent Restenosis and Inflammatory Markers. Cengiz Ozturk1, Ahmet Ozturk4, Mustafa Aparci3, Sevket Balta2, Mustafa Demir1, Ali Osman Yildirim1. 1 Department of Cardiology, Gulhane Medical Faculty, Ankara, Turkey; 2Department of Cardiology, Eskisehir Military Hospital, Eskisehir, Turkey; 3Department of Cardiology, Kasımpasa Military Hospital, Istanbul, Turkey; 4 Department of Geriatric Medicine, Gulhane Medical Faculty, Ankara, Turkey. Background: Inflammation markers may play a part in the pathogenesis of atherosclerosis and inflammatory reaction may play a role instent restenosis (ISR) after stent implantation. The aim of the our study was to investigate the predictive value of some inflammatory markers on development of in-stent restenosis in patients undergoing stent implantation. Methods: Patients presenting with angiographically documented ISR (diameter stenosis 50% by visual estimation) were included as a study group(53 subjects) and the patients presenting with angiographically documented no ISR (diameter stenosis < 50% by visual estimation) as a control group(53 subjects). There were 15/9 females/males in control group and 38/44 females/males in study group. There were 13 patients witn diabetes mellitus in control group and 16 patients in study group. The whole groups were compared with age, lipid profiles and fasting levels of glucose. Also, hematologic parameters were measured as part of the automated complete blood count. Results: There were no statistically significant differences in baseline charecteristics between two groups. Platelet-lymphocyte ratio (PLR), lymphocyte count, lymphocyte-platelet distrubition width ratio (LPR) were not significantly higher in patients with study group compared with those of controls. But, white blood counts, neutrophil counts and neutrophil and lymphocyte ratio(N/L ratio) were significantly higher in patients with study group compared with those of controls (Table-1). Conclusion: We believe that increased some inflammatory markers white blood counts, neutrophil counts may play a role in the pathogenesis of ISR based on atherosclerosis.
Coronary Artery Disease: Implications of Prevention and Early Diagnosis Sunday, March 29, 2015 08:30 AM w 10:00 AM, Hall 9 (Abstract nos. OP-191 w OP-197) - OP-191 Mental and Physical Quality of Life in Patients with Normal Coronary Artery. Ebru Altintas1, Fatma Yigit2. 1 Department of Psychiatry, Baskent University Medical Faculty Adana Teaching and Research Center, Adana; Turkey; 2Department of Cardiology, Baskent University Medical Faculty Adana Teaching and Research Center, Adana; Turkey. Background: Ten to thirty percent of angina like chest pain patients appears to have normal coronary arteries. Depression and anxiety disorders are most common mental disorders that accompanied to chest pain with normal coronary arteries patients. It is known that mental disorders and psychosocial factors are important in occurrence of angina like chest pain and sometimes in making repetitive coronary angiography. The aim of this study was to assess the mental and physical quality of life and psychiatric co morbidities in patient angina like chest pain with normal coronary angiography.
S86 The American Journal of Cardiologyâ MARCH 26e29, 2015 11th INTERNATIONAL CONGRESS OF UPDATE IN CARDIOLOGY AND CARDIOVASCULAR SURGERY ABSTRACTS / Oral
MARCH 26e29, 2015 Table Comparison of the groups according to socio-demographic characteristics, and anxiety, depression, and SF-36 quality of life scales score
Age Education Beck Depression Inventory Beck Anxiety Inventory Physical Functioning Physical Role Limitation Bodily Pain General Health Energy Social Functioning Emotional Role Limitation Mental Health Physical Quality of Life Mental Quality of Life
NCA (n¼87) Median (Min-Max)
CAD (n¼31) Median (Min-Max)
p
51(30-72) 5(5-15) 17(3-40) 24(5-50) 25(11-30) 4(4-8) 6.1(3-11) 12.5(5-22) 10(5-23) 7(3-10) 4(3-6) 14(7-28) 47(29-69) 35(19-63)
60(43-81) 5(5-15) 16(5-36) 17(5-32) 23(14-30) 4(4-8) 7(2-11) 15(5-22) 10(5-17) 8(2-10) 6(3-6) 16(7-25) 51(32-70) 38(17-56)
0.000 0.140 0.704 0.000 0.660 0.383 0.036 0.048 0.794 0.001 0.059 0.441 0.168 0.103
p: Kruscal Wallis test (p < 0.05) pGroup1&2, pGroup1&3, pGroup2&3: Post-hoc Mann Whitney U test (p0.017 bonferoni correction) NCA: Normal coronary arteries, CAD: Coronary Artery Diseases.
Materials-Methods: Eighty-seven patients with normal coronary angiography and thirty-one patients with coronary artery disease (CAD) were included to the study. The socio-demographic characteristics, co morbid disorders, Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI), and Health Related Quality of Life (HRQoL) scale scores were compared between groups. It was estimated using the short form (SF)-36 questionnaires for total HRQoL and its two dimensions for physical and mental health. Results: There were significant differences in age, gender, employment and psychiatric disorders history in family between two groups (Table 1). Anxiety scores were significantly higher level in NCA group. No difference was found in terms of depression between the NCA and CAD groups. There were significant differences in pain, general health and social function subgroups of SF-36 in NCA group. Physical and mental health was not differences between two groups. Psychiatric co morbidities were found in 82.8 % (n¼72) of the patients with normal angiographic findings and 54.8 % (n¼ 17) of the patients with angiographic coronary disease. Discussion: Our study suggests that impairment of the mental and physical health related quality of life is similar in normal and coronary artery disease patients. We found that Normal coronary arteries patients have been feel pain and social function and general health impairment to be more than CAD patients. Psychiatric co morbidity may conclude a risk factor to impairment of quality of life in normal coronary angiography patients.
- OP-192 The Relationship of The Healthy Lifestyle Behaviors and Cardiovascular Disease Risk Factors Knowledge Level of Patients with Cardiovascular Disease and Their Relatives. Sevda Korkut Bayındır1, Gulsum Nihal Guleser1, Abdurrahman Oguzhan2. 1Faculty of Health Sciences, Erciyes University, Kayseri, Turkey; 2Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Objectives: The aim of this study is to determine relationship of cardiovascular disease risk factors knowledge level and healthy life style behaviors of patient having cardiovascular disease and their relatives. Methods: This descriptive study was conducted between January 2014 and September 2014 in 126 patients with cardiovascular disease and 109 relatives. Data were collected by the researcher using questionnaire form, Cardiovascular Disease Risk Factors Knowledge Level (CARRF-KL) scale and Healthy Living Style Behaviors Scale-II (HLSBS-II). Descriptive statistics and correlation analysis were used to evaluate the data. Results: It has been determined that the average age of patients and their relatives were 59.713.1 and 44.314.8, respectively. Total CARRF-KL and HLSBS-II score average of patients and their relatives were 18.74.1, 19.35.8 and 117.919.1, 119.723.2, respectively. There was a significant, positive correlation between CARRF-KL and HLSBS-II score patients and relatives (r¼0.551, p¼0.00), (r ¼0.398, p¼0.00), respectively. The relationship significant positive side was determined between CARRF-KL and physical activity (r¼0.381, p¼0.00), health responsibility (r¼0.484, p¼0.00), spiritual growth (r¼0.513, p¼0.00), interpersonal relationships (r¼0.321, p¼0.00), nutrition (r¼0.374, p¼0.00) and stress management (r¼0.495, p¼0.00) score patients. The relationship significant positive side was determined between CARRF-KL and physical activity (r¼0.244, p¼0.01), health responsibility (r¼0.395, p¼0.00), spiritual growth (r¼0.302, p¼0.00), interpersonal relationships (r¼0.299, p¼0.00), nutrition (r¼0.343, p¼0.00) and stress management (r¼0.324, p¼0.00) score relatives. It has been determined that as the score of CARRF-KL increases, scores of HLSBS-II, physical activity, health responsibility, spiritual growth, interpersonal relationships, nutrition, and stress management increase. Conclusion: It is recommended that nurses should be given education about cardiovascular disease risk factors, prevention and management to patients and their relatives.
- OP-193 King is Naked. Aytekin Oguz, Ozge Telci Caklili. Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine. Objective: The University Group Diabetes Program (UGDP) study showed sulfonylureas may bring more harm than benefit to diabetic patients. Since then there has been no strong evidence proving sulfonylureas can prevent mortality or major cardiovascular clinical events. But sulfonylureas are still widely used in diabetes treatment. ORIGIN study has shown that insulin treatment which was considered as the most effective and natural remedy of diabetes for many years, had no beneficial effect on mortality and complications of diabetes. Is it reasonable to treat a disease with hyperinsulinemia and insulin resistance with insulin or insulin secretagogues. In this study we aimed to evaluate the type 2 diabetes treatment perception of doctors practicing in internal medicine. Method: A survey about type 2 diabetes treatment and relevant complications were conducted on 29 doctors practicing internal medicine. A questionnaire about their choices in treatment of type 2 diabetes and how much they have faith in those drugs was filled by participants. Results: Metformin was the most preferred agent as first line therapy. Sixty-five percent of the participants found it unnecessary to use insulin for treating a disease characterized with hyperinsulinemia however 73% claimed preferring insulin treatment frequently.
The American Journal of Cardiologyâ MARCH 26e29, 2015 11th INTERNATIONAL CONGRESS OF UPDATE IN CARDIOLOGY AND CARDIOVASCULAR SURGERY ABSTRACTS / Oral
S87
O R A L A B S T R A C T S