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PAPILLARY CYSTADENOCARCINOMA: A CASE REPORT
ABSTRACTS
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ACINETOBACTER BAUMANNII OROFACIAL CELLULITIS: REPORT OF 2 CASES. THAIS DOS SANTOS FONTES PEREIRA, RAISSA CRISTINA COSTA SILVA, MARIA EDILEUSA SANTOS, DENISE VIEIRA TRAVASSOS, CELIA REGINA LANZA, e GABRIELA ASSUNC ¸ AO GOEBEL and, TARCILIA APARECIDA SILVA Acinetobacter baumannii is a gram-negative microorganism with the ability to cause serious infections in critically ill patients. The present report describes 2 cases of A. baumannii orofacial cellulitis in hospitalized patients. A 12-year-old male patient diagnosed with acute promyelocytic leukemia in treatment of disease recurrence in the central nervous system presented an ulcerated lesion in the lip, suggestive of local trauma. The condition evolved with epithelial necrosis and nonspecific vesicles. Hemoculture was positive for multiresistant A. baumannii susceptible only to tigecycline. Despite antibiotic therapy, he died within 10 days. The second case occurred in a 10-year-old male patient with diagnosis of Burkitt lymphoma secondary to immunosuppression for treatment of giant cell hepatitis. The patient was under chemotherapy and evolved with mucositis grade IV. A. baumannii infection was detected in hemoculture, and the patient was treated with meropenem and polymyxin B. The patient died of complications from the primary disease.
SURGICAL TREATMENT OF EXTENSIVE RESIDUAL CYST IN MANDIBLE: CASE REPORT. RAFAEL SARAIVA TORRES, SAULO LOBO CHATEAUBRIAND DO NASCIMENTO, RENATA GUALBERTO DA CUNHA, GESSICA VASCONCELOS GODINHO, LOUISIMARA JESUS GARCIA ALENCAR, GUSTAVO CAVALCANTI DE ALBUQUERQUE and, MARCELO VINICIUS DE OLIVEIRA The residual cyst is the result of Malassez’s epithelial rests stimulation due to an inflammatory process of pulp necrosis of a tooth already removed. The aim of this work is to report an extensive residual cyst enucleation in the mandible. A 62-year-old female patient presented with pain in the right side of the mandible. Extraoral examination showed a growth caused by the extensive bulging of the buccal cortex in the edentulous region corresponding from the canine to the right molars area. The image obtained by concomitant computed tomography showed unilocular, hypodense, and well-defined limits, with expansion and thinning of the buccal bone plate of the corresponding region. An aspiration was performed followed by incisional biopsy, whose histopathologically analyzed tissue corresponded to the conclusive diagnosis of residual cyst. After 8 months of enucleation, no signs of relapse were observed, and the prognosis is good.
HISTOPATHOLOGIC ASPECTS OF JUVENILE OSSIFYING FIBROMA. AMANDA RAFAELA DA SILVA AMORIM, ALESKA DIAS e VANDERLEI, JOAO VICTOR MACEDO MARINHO, e CARLOS DE MELO ARAUJO, JOAO JOSE RICARDO ^ MIKAMI, JULIANA AROXA PEREIRA BARBOSA and, CAMILA MARIA BEDER RIBEIRO GIRISH PANJWANI Juvenile ossifying fibromas (JOFs) are benign fibro-osseous neoplasms observed in young individuals that, in cases of gneissic bones, are preferentially located in the maxilla and have
OOOO January 2020 histopathologic features very similar to other benign fibro-osseous lesions (BFOL). A 17-year-old male adolescent presented asymptomatic volume increase located in the right maxillary ridge region with a 6-month history of radiographic examination, showing the presence of mixed lesion with clear borders and a radiopaque center, an aspect of ground glass, and displacement of teeth. Histologic sections stained with hematoxylin and eosin (HE) revealed fragments a JOF with presence of cellular fibrous connective tissue containing spherical ossicles with basophilic centers and peripheral eosinophilic margins with JOF diagnosis. In this case, the outstanding histopathologic characteristics of the JOF are presented to differentiate it from the BFOL.
HISTOPATHOLOGIC ASPECTS OF PERIPHERAL OSSIFYING FIBROMA ASSOCIATED WITH ODONTOGENIC EPITHELIUM ISLANDS. AMANDA RAFAELA DA SILVA AMORIM, e CARLOS DE MELO ARAUJO, JOAO PEDRO THALLES BERNARDO DE CARVALHO NOGUEIRA, JOSE DE ^ AMORIM LISBOA NETO, JULIANA AROXA PEREIRA BARBOSA, MOHAMMED NADIMUL ISLAM and, CAMILA MARIA BEDER RIBEIRO GIRISH PANJWANI The peripheral ossifying fibroma (POF) is a relatively common gingival growth of a reactive nature. We present the case of a 49-year-old female patient who presented with a gingival nodule perceived during pregnancy that persisted about 18 years. Histologic sections stained with hematoxylin and eosin (HE) revealed fragments of mucosa with parakeratinized stratified squamous epithelium underlined by highly cellular connective tissue with plump fibroblast arranged in interlacing fascicles was seen. Osteoid rim was seen around few bony trabeculae along with numerous blood vessels with included odontogenic epithelium. The histopathologic finds of this lesion are discussed, and comparisons are made with other reports in the literature.
PAPILLARY CYSTADENOCARCINOMA: A e CASE REPORT. GLAUCE GUIMARAES PEREIRA, PABLYANNNE TEREZA LOUZADA GUEDES, WILKELLY ALVES DE LIMA, DANIEL CAVALLERO COLARES UCHOA, ANA CAROLINA ^A SANTIAGO DA SILVA, FLAVIA SIROTHEAU CORRE PONTES and, HELDER ANTONIO REBELO PONTES Papillary cystadenocarcinoma (PCC) is a rare malignant tumor of the salivary glands featured by cysts and papillary endocystic projections. The differential diagnosis includes cystadenoma, papillary-cystic variant of acinic cell carcinoma polymorphous low-grade adenocarcinoma (PLGA), salivary duct carcinoma, and adenoid cystic carcinoma (ACC). Nuclear pleomorphism, mitosis, and infiltrative growth pattern affirm the malignancy of PCC. A 66-year-old man presented with a swelling in the upper alveolar ridge and hard palate. Intraorally, an exophytic, friable and ulcerated lesion was observed. Computed tomography scan showed a large soft tissue mass destroying the left maxilla. An incisional biopsy was performed. Based on the histopathologic features of papillary projections extending into the cystic lumen, the diagnosis of PCC was confirmed. The patient was referred to an oncology center where chemotherapy and radiotherapy were chosen as the appropriate treatment. Currently, no signs of recurrence were detected after 2 years of clinical follow-up.
e126
ACINETOBACTER BAUMANNII OROFACIAL CELLULITIS: REPORT OF 2 CASES. THAIS DOS SANTOS FONTES PEREIRA, RAISSA CRISTINA COSTA SILVA, MARIA EDILEUSA SANTOS, DENISE VIEIRA TRAVASSOS, CELIA REGINA LANZA, e GABRIELA ASSUNC ¸ AO GOEBEL and, TARCILIA APARECIDA SILVA Acinetobacter baumannii is a gram-negative microorganism with the ability to cause serious infections in critically ill patients. The present report describes 2 cases of A. baumannii orofacial cellulitis in hospitalized patients. A 12-year-old male patient diagnosed with acute promyelocytic leukemia in treatment of disease recurrence in the central nervous system presented an ulcerated lesion in the lip, suggestive of local trauma. The condition evolved with epithelial necrosis and nonspecific vesicles. Hemoculture was positive for multiresistant A. baumannii susceptible only to tigecycline. Despite antibiotic therapy, he died within 10 days. The second case occurred in a 10-year-old male patient with diagnosis of Burkitt lymphoma secondary to immunosuppression for treatment of giant cell hepatitis. The patient was under chemotherapy and evolved with mucositis grade IV. A. baumannii infection was detected in hemoculture, and the patient was treated with meropenem and polymyxin B. The patient died of complications from the primary disease.
SURGICAL TREATMENT OF EXTENSIVE RESIDUAL CYST IN MANDIBLE: CASE REPORT. RAFAEL SARAIVA TORRES, SAULO LOBO CHATEAUBRIAND DO NASCIMENTO, RENATA GUALBERTO DA CUNHA, GESSICA VASCONCELOS GODINHO, LOUISIMARA JESUS GARCIA ALENCAR, GUSTAVO CAVALCANTI DE ALBUQUERQUE and, MARCELO VINICIUS DE OLIVEIRA The residual cyst is the result of Malassez’s epithelial rests stimulation due to an inflammatory process of pulp necrosis of a tooth already removed. The aim of this work is to report an extensive residual cyst enucleation in the mandible. A 62-year-old female patient presented with pain in the right side of the mandible. Extraoral examination showed a growth caused by the extensive bulging of the buccal cortex in the edentulous region corresponding from the canine to the right molars area. The image obtained by concomitant computed tomography showed unilocular, hypodense, and well-defined limits, with expansion and thinning of the buccal bone plate of the corresponding region. An aspiration was performed followed by incisional biopsy, whose histopathologically analyzed tissue corresponded to the conclusive diagnosis of residual cyst. After 8 months of enucleation, no signs of relapse were observed, and the prognosis is good.
HISTOPATHOLOGIC ASPECTS OF JUVENILE OSSIFYING FIBROMA. AMANDA RAFAELA DA SILVA AMORIM, ALESKA DIAS e VANDERLEI, JOAO VICTOR MACEDO MARINHO, e CARLOS DE MELO ARAUJO, JOAO JOSE RICARDO ^ MIKAMI, JULIANA AROXA PEREIRA BARBOSA and, CAMILA MARIA BEDER RIBEIRO GIRISH PANJWANI Juvenile ossifying fibromas (JOFs) are benign fibro-osseous neoplasms observed in young individuals that, in cases of gneissic bones, are preferentially located in the maxilla and have
OOOO January 2020 histopathologic features very similar to other benign fibro-osseous lesions (BFOL). A 17-year-old male adolescent presented asymptomatic volume increase located in the right maxillary ridge region with a 6-month history of radiographic examination, showing the presence of mixed lesion with clear borders and a radiopaque center, an aspect of ground glass, and displacement of teeth. Histologic sections stained with hematoxylin and eosin (HE) revealed fragments a JOF with presence of cellular fibrous connective tissue containing spherical ossicles with basophilic centers and peripheral eosinophilic margins with JOF diagnosis. In this case, the outstanding histopathologic characteristics of the JOF are presented to differentiate it from the BFOL.
HISTOPATHOLOGIC ASPECTS OF PERIPHERAL OSSIFYING FIBROMA ASSOCIATED WITH ODONTOGENIC EPITHELIUM ISLANDS. AMANDA RAFAELA DA SILVA AMORIM, e CARLOS DE MELO ARAUJO, JOAO PEDRO THALLES BERNARDO DE CARVALHO NOGUEIRA, JOSE DE ^ AMORIM LISBOA NETO, JULIANA AROXA PEREIRA BARBOSA, MOHAMMED NADIMUL ISLAM and, CAMILA MARIA BEDER RIBEIRO GIRISH PANJWANI The peripheral ossifying fibroma (POF) is a relatively common gingival growth of a reactive nature. We present the case of a 49-year-old female patient who presented with a gingival nodule perceived during pregnancy that persisted about 18 years. Histologic sections stained with hematoxylin and eosin (HE) revealed fragments of mucosa with parakeratinized stratified squamous epithelium underlined by highly cellular connective tissue with plump fibroblast arranged in interlacing fascicles was seen. Osteoid rim was seen around few bony trabeculae along with numerous blood vessels with included odontogenic epithelium. The histopathologic finds of this lesion are discussed, and comparisons are made with other reports in the literature.
PAPILLARY CYSTADENOCARCINOMA: A e CASE REPORT. GLAUCE GUIMARAES PEREIRA, PABLYANNNE TEREZA LOUZADA GUEDES, WILKELLY ALVES DE LIMA, DANIEL CAVALLERO COLARES UCHOA, ANA CAROLINA ^A SANTIAGO DA SILVA, FLAVIA SIROTHEAU CORRE PONTES and, HELDER ANTONIO REBELO PONTES Papillary cystadenocarcinoma (PCC) is a rare malignant tumor of the salivary glands featured by cysts and papillary endocystic projections. The differential diagnosis includes cystadenoma, papillary-cystic variant of acinic cell carcinoma polymorphous low-grade adenocarcinoma (PLGA), salivary duct carcinoma, and adenoid cystic carcinoma (ACC). Nuclear pleomorphism, mitosis, and infiltrative growth pattern affirm the malignancy of PCC. A 66-year-old man presented with a swelling in the upper alveolar ridge and hard palate. Intraorally, an exophytic, friable and ulcerated lesion was observed. Computed tomography scan showed a large soft tissue mass destroying the left maxilla. An incisional biopsy was performed. Based on the histopathologic features of papillary projections extending into the cystic lumen, the diagnosis of PCC was confirmed. The patient was referred to an oncology center where chemotherapy and radiotherapy were chosen as the appropriate treatment. Currently, no signs of recurrence were detected after 2 years of clinical follow-up.