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PO04-MO-06 C-Reactive protein level as a good predictive factor for short term prognosis after first ischemic stroke
19th World Congress of Neurology, Poster Abstracts / Journal of the Neurological Sciences 285 S1 (2009) S155–S339
factors. (P < 0.001) Lacunar infarct has significantly higher serum triglyceride levels than large artery atherosclerotic infarct or cardioembolic infarct. (p = 0.010) Patients with poor outcome had significantly lower serum triglyceride level than patients with good outcome (107.2±78.8 versus 119.7±66.7 mg/dl) with adjustment of age, sex and risk factors. (p = 0.013). Conclusion: Higher serum triglyceride levels is associate with less severe stroke and good outcome.
S171
PO04-MO-05 Determination of the role of leukocytosis and increased erythrocytes sedimentation rate as effective factors in ischemic stroke prognosis
Results: The CRP level increased during first to sixth days and the CRP difference had good correlation (R: 0.437, P value <0.001) with degree of disability at disgharge, also CRP of first day (CRP1) had good correlation (R: 0.605, P value <0.001) with disability and based on the ROC curve cutoff point >1.75 mg/dl for CRP1 could predict worse short outcome with sensitivity of 74% and specificity of 75%. Fasting blood glucose level had moderate correlation (R: 0.321, P < 0.001) with the worse outcome at discharge. All of correlations have been consistent after multivariance analysis. Conclusion: Similar to the long term prognosis the first day CRP level can be a good independent predictor for short term prognosis after first ischemic stroke so that cutoff point >1.75 can predict a worse short outcome.
S.H.D. Shaafi1 , M. Nikanfar2 . 1 Neurology, Tabriz University of Medical Sciene, Tabriz, Islamic Republic of Iran; 2 Tabriz University, Tabriz, Islamic Republic of Iran
PO04-MO-07 Evaluation of sexuality in stroke patients
In a near future, stroke will be the second leading cause of death and disability in many regions of the world. The identification of predictors for death and poor outcome might contribute to reduce mortality and morbidity rates after stroke by enhancing the application of specific therapeutic and management strategies to patients at high risk. Leukocytosis and increased erythrocyte sedimentation rate (ESR) during the early phases of acute ischemic stroke has been proposed to be related with poor prognosis. This study aimed at evaluating theses two parameters in patients with ischemic stroke. Methods and Materials: In an analytic study, 150 patients with confirmed ischemic stroke hospitalized were reviewed during a 13-month period. The white blood cell (WBC) count and ESR were determined on admitting and 3 days after. The patients categorized into three groups: expired during hospital stay, discharged in good situation (Rankin’s scale of 0–2), discharged in poor situation (Rankin’s scale of 3–5). Results: One hundred fifty patients, 75 males and 75 females, with the mean age of 67.3±8.2 (48–88) years enrolled in this study. There were 32 (21.3%) expired cases, 26 (17.3%) cases discharged in good condition and 92 (61.3%) cases discharged in poor condition. Leukocytosis on day one was significantly more prevalent in patients passed away during hospitalization or discharged in notso-well condition. High WBC and ESR levels, altered consciousness, diffused lesions in CT scan, and imperfect neurological condition on day one, as well as positive history of DM and HTN were significantly related with higher in-hospital death rate and/or poor condition at discharge. Conclusion: This study showed that the raised WBC count and ESR just after an ischemic stroke attack might be related with a poor prognosis and necessitate immediate and meticulous monitoring and therapies. PO04-MO-06 C-Reactive protein level as a good predictive factor for short term prognosis after first ischemic stroke M.R. Gheini, H. Cheraghmakani, A. Meysamie Pasha. Tehran University of Medical Science, Sina Hospital, Tehran, Islamic Republic of Iran Purpose: Recent studies described an association between levels of CRP and long term outcome after ischemic stroke. We studied the predictive value of first and sixth day CRP levels on short term prognosis after first ischemic stroke. Methods: 134 consecutive patients without thrombolysis with a first ischemic stroke were examined during the first, sixth and dischrge days after symptoms onset and their CRP have been measured at the first and sixth days with high-sensitive assay. Patients that had infection or malignancy or any inflammatory disorders have been excluded. In addition to several cerebrovascular risk factors the short term outcome at sixth and disgharge days and CRPs correlations with them were determined.
Y. Tamam1 , L. Tamam2 , E. Akil1 , A. Yasan3 , B. Tamam4 . 1 Neurology, Dicle University Faculty of Medicine, Diyarbakir, Turkey; 2 Psychiatry, Cukurova University Faculty of Medicine, Adana, Turkey; 3 Psychiatry, Dicle University Faculty of Medicine, Diyarbakir, Turkey; 4 Neurology, Dicle State Hospital, Diyarbakir, Turkey Purpose: Medical problems and complications after stroke have been well studied. However there is little information on one of the important aspects of the quality of life of those patients, namely sexual functioning and satisfaction. The aim of this study was to assess the impact of stroke on sexual functioning in a stable cohort of Turkish stroke patients with mild or no disability and to assess the relationship between post-stroke sexuality and a number of socio-demographic, clinical and laboratory variables. Method: The sexual functioning of 165 Turkish stroke patients with no disability or mild disability was assessed in two consecutive interviews along with clinical and sociodemographic features. NIH stroke, Glasgow coma, Barthel, and Rankin scales were also applied to assess neurologic status and disability. Results: Most of the patients in this study were male (68%) and illiterate (73%). There was a significant difference between the baseline and post-stroke frequency of sexual activity of the patients. The differences between baseline and post-stroke vaginal lubrication, orgasms and satisfaction were all statistically significant. The latter difference was significant for both genders. Frequency of coitus both prior to and after the stroke was significantly different between males and females. Erection and ejaculation of the males was significantly affected by the stroke, and lubrication and orgasm was affected in the females. Interestingly, fear of recurrent stroke did not differ between genders. Conclusion: The present study confirmed that Turkish stroke survivors have sexual health needs during the rehabilitation process, though this has not been addressed previously. Sexual health needs could be affected by cultural factors and biases. PO04-MO-08 Survey depression screening in Thai stroke patients: case study of Bangkok Hospital T. Petchsuk. Brain, Bangkok Hospital, Bangkok, Thailand Purpose: The purpose of this research was to survey and assessment for depression with cerebrovascular disease patients and to find out associations between personal factors and depressive status with cerebrovascular disease patients. Method: A purposive random sampling method was used to recruit a sampling. This consisted of 100 peoples that were used to service at Bangkok Hospital. The questionnaires that used composed of the instrument were a personnel information and rating-scale questionnaire on depressive status. The data were collected from January 1 to December 31, 2008. Descriptive statistics and chisquare were employed to analyze the data. They were find out a personnel information and scores of associations between depression and cerebrovascular disease.
factors. (P < 0.001) Lacunar infarct has significantly higher serum triglyceride levels than large artery atherosclerotic infarct or cardioembolic infarct. (p = 0.010) Patients with poor outcome had significantly lower serum triglyceride level than patients with good outcome (107.2±78.8 versus 119.7±66.7 mg/dl) with adjustment of age, sex and risk factors. (p = 0.013). Conclusion: Higher serum triglyceride levels is associate with less severe stroke and good outcome.
S171
PO04-MO-05 Determination of the role of leukocytosis and increased erythrocytes sedimentation rate as effective factors in ischemic stroke prognosis
Results: The CRP level increased during first to sixth days and the CRP difference had good correlation (R: 0.437, P value <0.001) with degree of disability at disgharge, also CRP of first day (CRP1) had good correlation (R: 0.605, P value <0.001) with disability and based on the ROC curve cutoff point >1.75 mg/dl for CRP1 could predict worse short outcome with sensitivity of 74% and specificity of 75%. Fasting blood glucose level had moderate correlation (R: 0.321, P < 0.001) with the worse outcome at discharge. All of correlations have been consistent after multivariance analysis. Conclusion: Similar to the long term prognosis the first day CRP level can be a good independent predictor for short term prognosis after first ischemic stroke so that cutoff point >1.75 can predict a worse short outcome.
S.H.D. Shaafi1 , M. Nikanfar2 . 1 Neurology, Tabriz University of Medical Sciene, Tabriz, Islamic Republic of Iran; 2 Tabriz University, Tabriz, Islamic Republic of Iran
PO04-MO-07 Evaluation of sexuality in stroke patients
In a near future, stroke will be the second leading cause of death and disability in many regions of the world. The identification of predictors for death and poor outcome might contribute to reduce mortality and morbidity rates after stroke by enhancing the application of specific therapeutic and management strategies to patients at high risk. Leukocytosis and increased erythrocyte sedimentation rate (ESR) during the early phases of acute ischemic stroke has been proposed to be related with poor prognosis. This study aimed at evaluating theses two parameters in patients with ischemic stroke. Methods and Materials: In an analytic study, 150 patients with confirmed ischemic stroke hospitalized were reviewed during a 13-month period. The white blood cell (WBC) count and ESR were determined on admitting and 3 days after. The patients categorized into three groups: expired during hospital stay, discharged in good situation (Rankin’s scale of 0–2), discharged in poor situation (Rankin’s scale of 3–5). Results: One hundred fifty patients, 75 males and 75 females, with the mean age of 67.3±8.2 (48–88) years enrolled in this study. There were 32 (21.3%) expired cases, 26 (17.3%) cases discharged in good condition and 92 (61.3%) cases discharged in poor condition. Leukocytosis on day one was significantly more prevalent in patients passed away during hospitalization or discharged in notso-well condition. High WBC and ESR levels, altered consciousness, diffused lesions in CT scan, and imperfect neurological condition on day one, as well as positive history of DM and HTN were significantly related with higher in-hospital death rate and/or poor condition at discharge. Conclusion: This study showed that the raised WBC count and ESR just after an ischemic stroke attack might be related with a poor prognosis and necessitate immediate and meticulous monitoring and therapies. PO04-MO-06 C-Reactive protein level as a good predictive factor for short term prognosis after first ischemic stroke M.R. Gheini, H. Cheraghmakani, A. Meysamie Pasha. Tehran University of Medical Science, Sina Hospital, Tehran, Islamic Republic of Iran Purpose: Recent studies described an association between levels of CRP and long term outcome after ischemic stroke. We studied the predictive value of first and sixth day CRP levels on short term prognosis after first ischemic stroke. Methods: 134 consecutive patients without thrombolysis with a first ischemic stroke were examined during the first, sixth and dischrge days after symptoms onset and their CRP have been measured at the first and sixth days with high-sensitive assay. Patients that had infection or malignancy or any inflammatory disorders have been excluded. In addition to several cerebrovascular risk factors the short term outcome at sixth and disgharge days and CRPs correlations with them were determined.
Y. Tamam1 , L. Tamam2 , E. Akil1 , A. Yasan3 , B. Tamam4 . 1 Neurology, Dicle University Faculty of Medicine, Diyarbakir, Turkey; 2 Psychiatry, Cukurova University Faculty of Medicine, Adana, Turkey; 3 Psychiatry, Dicle University Faculty of Medicine, Diyarbakir, Turkey; 4 Neurology, Dicle State Hospital, Diyarbakir, Turkey Purpose: Medical problems and complications after stroke have been well studied. However there is little information on one of the important aspects of the quality of life of those patients, namely sexual functioning and satisfaction. The aim of this study was to assess the impact of stroke on sexual functioning in a stable cohort of Turkish stroke patients with mild or no disability and to assess the relationship between post-stroke sexuality and a number of socio-demographic, clinical and laboratory variables. Method: The sexual functioning of 165 Turkish stroke patients with no disability or mild disability was assessed in two consecutive interviews along with clinical and sociodemographic features. NIH stroke, Glasgow coma, Barthel, and Rankin scales were also applied to assess neurologic status and disability. Results: Most of the patients in this study were male (68%) and illiterate (73%). There was a significant difference between the baseline and post-stroke frequency of sexual activity of the patients. The differences between baseline and post-stroke vaginal lubrication, orgasms and satisfaction were all statistically significant. The latter difference was significant for both genders. Frequency of coitus both prior to and after the stroke was significantly different between males and females. Erection and ejaculation of the males was significantly affected by the stroke, and lubrication and orgasm was affected in the females. Interestingly, fear of recurrent stroke did not differ between genders. Conclusion: The present study confirmed that Turkish stroke survivors have sexual health needs during the rehabilitation process, though this has not been addressed previously. Sexual health needs could be affected by cultural factors and biases. PO04-MO-08 Survey depression screening in Thai stroke patients: case study of Bangkok Hospital T. Petchsuk. Brain, Bangkok Hospital, Bangkok, Thailand Purpose: The purpose of this research was to survey and assessment for depression with cerebrovascular disease patients and to find out associations between personal factors and depressive status with cerebrovascular disease patients. Method: A purposive random sampling method was used to recruit a sampling. This consisted of 100 peoples that were used to service at Bangkok Hospital. The questionnaires that used composed of the instrument were a personnel information and rating-scale questionnaire on depressive status. The data were collected from January 1 to December 31, 2008. Descriptive statistics and chisquare were employed to analyze the data. They were find out a personnel information and scores of associations between depression and cerebrovascular disease.