- Email: [email protected]
Reye of Reye’s syndrome
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RUHNKE ET AL
GASTROENTEROLOGY Vol. 128, No. 7
to primary human hepatocytes for autologous cell therapy. Transplantation (in press). 33. Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med 2004;10: 744 –748. 34. Jang YY, Collector MI, Baylin SB, Diehl AM, Sharkis SJ. Hematopoietic stem cells convert into liver cells within days without fusion. Nat Cell Biol 2004;6:532–539.
Received May 26, 2004. Accepted March 2, 2005. Address requests for reprints to: Fred Fändrich, MD, Department of General Surgery and Thoracic Surgery, UK-SH, Campus Kiel, Arnold-Heller Strasse 7, D-24105 Kiel, Germany. e-mail: [email protected]; fax: (00) 49-431-597-4586. M.R. and H.U. contributed equally to this work. The authors thank I. Schellhorn, I. Berg, and M. Jansen for excellent technical assistance.
Reye of Reye’s syndrome
Courtesy of the Royal Alexandra Hospital for Children, Sydney, Australia.
Ralph Douglas Kenneth Reye (1912–1977) was born in Townsville, Queensland, Australia, the youngest of 7 children sired by an emigré from the Black Forest region of Germany. The surname is pronounced “rye,” as the cereal. His entire scholastic and professional life was spent in Sydney where he received his MB degree in 1937 and his MD degree in 1945. In 1942, he married Carrie Saunders, a medical school classmate, who became noted in her own right for her work in the rehabilitation of children with cerebral palsy. Appointed director of pathology at the Children’s Hospital of Sydney, he later confined his interest to histopathology. He authored fewer than 30 papers during his career, but several have become notable in the annals of medicine. The best known is his description of encephalopathy associated with fatty degeneration of viscera, including microvesicular steatosis of the liver (Lancet 1963;2:749 –752), an entity whose pathogenesis remains elusive. A tall, quiet, reserved man, Reye was thoroughly conversant with the literary and artistic world of his homeland. A highly polished, meticulously maintained, vintage white Jaguar automobile was his pride and joy. —Contributed by WILLIAM S. HAUBRICH, M.D. The Scripps Clinic, La Jolla, California
RUHNKE ET AL
GASTROENTEROLOGY Vol. 128, No. 7
to primary human hepatocytes for autologous cell therapy. Transplantation (in press). 33. Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med 2004;10: 744 –748. 34. Jang YY, Collector MI, Baylin SB, Diehl AM, Sharkis SJ. Hematopoietic stem cells convert into liver cells within days without fusion. Nat Cell Biol 2004;6:532–539.
Received May 26, 2004. Accepted March 2, 2005. Address requests for reprints to: Fred Fändrich, MD, Department of General Surgery and Thoracic Surgery, UK-SH, Campus Kiel, Arnold-Heller Strasse 7, D-24105 Kiel, Germany. e-mail: [email protected]; fax: (00) 49-431-597-4586. M.R. and H.U. contributed equally to this work. The authors thank I. Schellhorn, I. Berg, and M. Jansen for excellent technical assistance.
Reye of Reye’s syndrome
Courtesy of the Royal Alexandra Hospital for Children, Sydney, Australia.
Ralph Douglas Kenneth Reye (1912–1977) was born in Townsville, Queensland, Australia, the youngest of 7 children sired by an emigré from the Black Forest region of Germany. The surname is pronounced “rye,” as the cereal. His entire scholastic and professional life was spent in Sydney where he received his MB degree in 1937 and his MD degree in 1945. In 1942, he married Carrie Saunders, a medical school classmate, who became noted in her own right for her work in the rehabilitation of children with cerebral palsy. Appointed director of pathology at the Children’s Hospital of Sydney, he later confined his interest to histopathology. He authored fewer than 30 papers during his career, but several have become notable in the annals of medicine. The best known is his description of encephalopathy associated with fatty degeneration of viscera, including microvesicular steatosis of the liver (Lancet 1963;2:749 –752), an entity whose pathogenesis remains elusive. A tall, quiet, reserved man, Reye was thoroughly conversant with the literary and artistic world of his homeland. A highly polished, meticulously maintained, vintage white Jaguar automobile was his pride and joy. —Contributed by WILLIAM S. HAUBRICH, M.D. The Scripps Clinic, La Jolla, California