Schedule of oral presentations

SOCIETY OF PERINATAL OBSTETRICIANS Miami Beach, Florida - February 2-7, 1998

Schedule of Oral Presentations Thursday, February 5, 1998 7:45 a.m. to 10:00 a.m.

Oral Plenary Session I

Grand Ballroom East

Moderators: Steven L. Clark, MD, President Donald R. Coustan, MD, Immediate Past President

7:45-8:00

WELCOME AND ANNOUNCEMENTS

8:00-8:15

MATERNAL HUMAN IMMUNODEFICIENCY VIRUS (HIV) RNA LEVEL CORRELATES WITH THE RISK BUT DOES NOT PREDICT THE TIMING OF PERINATAL TRANSMISSION

Garcia PM. Kalish L Pitt J, Quinn T, Burchett S, Hanson C, MinkoffH, Jackson B, Moye J, Lew Z Northwestern University, Chicago, IL; New England Research Institute; Columbia College of Physicians and Surgeons; Johns Hopkins University; Harvard Medical School; Baylor College of Medicine; SUNY; NICHD; NIAID

8:15-8:30

2

PREDICTION OF PRETERM BIRTH WITH AMBULATORY MEASUREMENT OF UTERINE CONTRACTION FREQUENCY (UCF)

lares JD. NICHD MFMU Network, Bethesda, MD

8:30-8:45

3

CEMAT (CANADIAN EARLY (EA) VS. MIDRTIMESTER (MA) AMNIOCENTESIS TRIAL) PROSPECTIVE RANDOMIZED EVALUATION: FINAL PRIMARY RESULTS.

Wilson RD. CEMAT Group

8:45-9:00

4

INTRAAMNIOTIC RETROVIRAL-MEDIATED GENRE TRANSFER IN THE PRETERM OVINE FETUS

Galan 11. Schaack J, Owens GC, Hayward A, 73,son W, Hobbins J, Depts. of Ob/Gyn, Microbio, Path., Immunol., and Biochem. & Mol. Gen., UCHSC and Children's Hospital, Denver, CO

9:00-9:15

5

THE FETAL INFLAMMATORY RESPONSE SYNDROME IS CHARACTERIZED BY THE OUTPOURING OF A POTENT EXTRACELLULAR MATRIX DEGRADING ENZYME INTO THE FETAL CIRCULATION

Romero R. Athayde N, Gomez R, Mazor M, Yoon BH, Edwin S, Ghezzi E Berry SM, Dept. Ob/Gyn, Wayne State University/Hutzel Hospital, Detroit, MI, and the Perinatology Research Branch/NICHD

9:15-9:30

6

SUBCLINICAL SHEDDING OF HERPES SIMPLEX VIRUS (HSV) AT THE TIME OF LABOR

Brown Z, Hume RE Selke S, Zeh J, Ashley R, Watts DH, Berry S, Herd M, Corey L, Depts. of Ob/Gyn and Lab. Med., Univ. of Wash., Seatde, WA and Dept. Ob/Gyn, Madigaa Army Medical Center, Tacoma, WA

9:30-9:45

7

PREECLAMPTIC WOMEN WITH HEADACHE ARE MUCH MORE LIKELY TO HAVE ABNORMAL CEREBRAL PERFUSION THAN THOSE WITHOUT

Belfort M. Wihman 1, Grunewald C, Saade G, Dildy GA, Dorman K, Abedejos P, Herd A, Depts of Ob/Gyn, and Medicine, IHC and Univ. of Utah, Salt Lake City, UT; Baylor College of Medicine, Houston, TX; Karolinska Institue, Stockholm, Sweden; and UTMB, Galveston, TX

9:45-10:00

8

ACTIVE PHASE LABOR ARREST: TWO HOURS OF OXYTOCIN AUGMENTATION IS NOT ENOUGH

Rouse DJ. Owen J, Hauth JC, Univ. of Alabama at Birmingham, AL

American Journal of Obstetrics and Gynecology

January 1998 XV

Thursday, February 5, 1998 .....

,

1:00 p.m. to 3:30 p.nll

in

Oral Concurrent Sessxon A

....

Fontainebleau Ballroom A/B

Preeclampsia/Hypertensive Disease Maternal-Fetal Physiology Moderators:

James M. Roberts, MD Baha M. Sibai, MD Marshall Lindheimer, MD, 1998 Honorary Member

1:00-1 : 15

9

AN ANGIOTENSINOGEN PROMOTER MUTATION IS ASSOCIATED WITH PREECLAMPSIA

.W_~d K, Leavitt M, Nelson L, Farrington PE Lalouel JM, Depts. of Ob/Gyn and Human Genetics, University of Utah School of Medicine, Salt Lake City, UT

1:15-1:30

10

TOTAL ARTERIAL CAPACITANCE IN MILD PREECLAMPSIA AND NORMAL PREGNANCY

Saadr G. Berry 19, Belfort M, Depts. of Ob/Gyn, The University of Texas Med. Branch, Galveston, TX; Baylor College of Medicine, Houston, TX; and University of Utah, Salt Lake City, UT

1:30-1:45

11

MATERNAL CENTRAL }-[EMODYNAMICS IN HYPERTENSIVE DISORDERS OF PREGNANCY - A LONGITUDINAL STUDY

Bo.ylo ~ O'Herlihy C, Conroy R, McKenna P, Rotunda Hospital and University College Dub/in, Ireland

1:45-2:00

12

ECLAMPSIA OCCURS WITH A SIGNIFICANT FALL IN CEREBROVASCULAR RESISTANCE

Williams K. Wilson S, B.C. Women's Hospital, Div. of Maternal Fetal Medicine, Vancover, B.C., Canada

2:00-2:15

13

INTERIM REPORT OF THE NIMODIPINE VS. MAGNESIUM SULFATE FOR SEIZURE PROPHYLAXIS IN SEVERE PREECLAMPSIA STUDY: AN INTERNATIONAL, RANDOMIZED, CONTROLLED TRIAL

Belfort M. Anthony J, Saade G, and the Nimodipine Study Group

2:15-2:30

14

EFFECT OF NORMAL PREGNANCY AND PREECLAMPSIA ON CONTRACTILITY OF ISOLATED HUMAN OMENTAL ARTERY

Vede~ikov y, Saade G, Belfort M, Garfield R, Depts. of Ob/Gyn, The University of Texas Meclical Branch, Galveston, TX; and Baylor College of Medicine, Houston, TX

2:30-2:45

15

METABOLISM, NOT TRANSPORT, IS ABNORMAL IN PERFUSED PLACENTAL COTYLEDONS OF IUGR FETUSES

Challis DE. Ritchie JWK, Tesoro AM, Knie B, Koren G, Adamson SL, Ob/Gyn, University of Toronto, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital & Clinical Pharm., Hospital for Sick Children, Toronto, Ontario, Canada

2:45-3:00

16

MATERNAL REGULATION OF EMBRYONIC GROWTH: THE ROLE OF VASOACTIVE INTESTINAL PEPTIDE

Soon~ CY Lee SJ, McCune SK, Gibney G, Brenneman DE, Hill JM, Sect. on Development and Molecular Pharmacology, LDN, NICHD, N/H, Bethesda, MD

3:00-3:15

17

FETAL COGNITION: CHARACTERISTICS OF AIRBORNE SOUNDS WHICH ELICIT COGNITIVE PROCESSING

Gmome LJ, Mooney DM, Holland SB, Smith LA, Atterbur7 JL, Dy "lonanRA, University of South Alabama, Mobile, AL

3:15-3:30

18

DOPPLER ULTRSOUND FINDINGS OF LUNG HYPOPLASIA IN FETAL LAMB MODEI.

Rasanen J. Sylvester KG, Kitano Y, Huhta JC, Adzick NS, Dept. of Ob/Gyn, Pennsylvania Hospital and The Children's Institute for Surgical Science; The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA

XVI

January 1998

American Journal of Obstetrics and Gynecology

Thursday, February 5, 1998 '(3ral Concurrent Session 13

Fontainebleau Ballroom C/D

Infectious Disease PerinataI Outcomes Moderators:

John P. Elliot, MD Ronald S. Gibbs, MD

1:00-1:15

19

A COST-EFFECTIVENESS AND OUTCOMES-BASED EVALUATION OF PRENATALCARRIER SCREENING FOR CYSTIC FIBROSIS (CF)

Vintzileos AM. Ananth CV, Fisher AJ, Smulial2 JC, Day-Salvatore D, Beazoglou T, Knuppel RA. Division(s) of Maternal-Fetal Medicine and Clinical Genetics, Dept. of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School/St. Peter's Medical Center, New Brunswick, NJ and Dept. of Pediatric Dentistry, Univ. of Connecticut Health Center, Farmington, CT

1:15-1:30

20

LONG-TERM INTELLECTUAL PERFORMANCE OF SUBJECTS AFTER BREECH DELl-VERY-A POPULATION BASED FOLLOW UP

Seidman DS, Schiff E, Laor A, Stevenson DK, Dept. of Ob/Gyn, Sheba Medical Center, TelAviv University Israel; Dept. Pediatrics, Stanford Univ., Stanford, CA

1:30-1:45

21

INSTITUTIONAL INFLUENCES ON CESAREAN SECTION RATES IN UTAH 1992-1995

Clark $1_. Xu W, Porter TF, Love D, Utah Dept. of Health, Intermountain Health Care and Univ. of Utah, Salt Lake City, UT

1:45-2:00

22

UNIVERSITY HOSPITAL BASED PRENATALCARE DECREASES THE RATE OF RECURRENT PRETERM DELIVERY AND COSTS WHEN COMPARED TO MANAGED CARE

Bienstock J, Ural S, Cox C, Blakemore K, Pressman E, Johns Hopkins Med. Institute, Baltimore, MD

2:00-2:15

23

IMPACT OF FETAL FIBRONECTIN ASSAY ON ADMISSIONS FOR PRETERM LABOR

Jo_ffe G. .lacqlles D. Burton B, Bemis-Heys R, Shelbur~e P, Lovelace Medical Center, Albuquerque, NM and Matria Healthcare, Marietta, GA

2:15-2:30

24

ANTENATAL PENICILLIN G BENZATHINE THERAPY IN GROUP B STREPTOCOCCUS CARRIERS

Weeks ]W. Adair CD, Lewis DF, Edwards MS, Silberman R, Myers SR, Dept. of Ob/Gyn, Louisiana State Univ. Medical Center, Shreveport, LA: Dept. Pharmacology & Toxicology, Univ. of Louisville School of Medicine, Louisville, KY

2:30-2:45

25

PUERPERAL INFECTION DUE TO GROUP-A STREPTOCOCCUS: ASSOCIATION OF M-PROTEIN TYPES AND EXOTOXIN GENES WITH MORBIDITY

~Wright L.I, Byrne JLB, Silver RM, Depts. of Ob/Gyn and Medicine, University of Utah, Salt Lake City, UT

2:45-3:00

26

ACYCLOVIR SUPPRESSION TO PREVENT CESAREAN DELIVERY AFTER FIRST EPISODE GENITAL HERPES S~r INFECTION

Scott LL Holtier LM, Jackson G, Sanchez PJ, Baum A, Wendel GD Jr, Univ. of Texas Southwestern Medical Center, Dallas, TX

3:00-3:15

27

VALACICLOVIR PHARMACOKINETICS IN LATE PREGNANCY

Kimberlin DF Weller S, Andrews W~, llalah JC, Whitley RJ, Lakeman F, Miller G, Lee C, Goldel~berg RL, Dept. of Ob/Gyn, Univ, of Alabama at Birmingham, AL

3:15-3:30

28

ROUTINE FOLLOW-UP SONOGRAPHY TO EVALUATE FETAL STRUCTURE IS UNNECESSARY

Perslr WH, Jones OW IlL Hobbins JC, Dept. Ob/Gyn, Univ. of Colorado, Denver, CO

American Journal of Obstetrics and Gynecology

January 1998 XVII

Friday, February 6, 1998 1

8:00 a.m. to 10:00 a.m.

Grand Ballroom East

Oral Plenary Session II Moderators:

Gary D. V. Hankins, MD Mary E. D'Alton, MD

800-8:15

29

PATHWAYS MEDIATING VASORELAXATION OF PREGNANT RAT UTERINE ARTERY BY CORTICO TROPIN-RELEASING FACTOR

Jam V Vedernikov Y, Saade G, Chwalbz K, GarfieM R, Dept. of Ob/Gyn, The Univ. of Texas Med. Branch, Galveston, TX; and Schering AG, Berlin, Germany

8:15-8:30

30

GENE TRANSFER INTO HUMAN TROPHOBLAST CELLS BY RECOMBINANT VIRAL VECTORS

Parry S. Holder J, Morgan MA, Strattrs JF III, Dept. of Ob/Gyn, University of Pennsylvania, Philadelphia, PA

8:30-8:45

31

COGNITIVE OUTCOME AT FIVE YEARS IS RELATED TO INTRA-UTERINE HEMODYNAMIC ADAPTATION TO GROWTH RESTRICTION AND TO VEP LATENCIES IN EARLY INFANCY

Scher_ion ~, Briet J, Kok J, Dept. of Ob/Gyn and Neonatology, Univ. of Amsterdam, The Netherlands

8:45-9:00

32

EFFECT OF LPS ON UTERINE CONTRACTION AND PROSTAGLANDIN PRODUCTION IN PREGNANT RATS

Okawa T, Suzuki H, Yanagida K, Sato A, Vedernikov Y, Saade G, Garfield R, Dept.s. of Ob/Gyn, The Univ. of Texas Med. Branch, Galveston, TX; and Fukushima Medical College, Fukushima, Japan

9:00-9:15

33

TRANSVAGINAL VERSUS TRANSPERINEAL ULTRASOUND: A BLINDED COMPARISON IN THE ASSESSMENT OF CERVICAL LENGTH AT MID-GESTATION

Kurtzma• ,I, Goldsmith L J, Gall S, Spinnato JA, Dept. of Ob/Gyn, University of Louisville, Louisville, KY

9:15-9:30

34

LONG-TERM DEVEI.OPMENTAL OUTCOME AFTER LNTRAUTERINE TRANSFUSION FOR THE TREATMENT OF FETAL HEMOLYTIC DISEASE

!:tltdoAL_Hegemier S, Hill R, Moise A, Smith O, Moise K, Dept. of Ob/Gyn, Div. of MaternalFetal Med. and Dept. of Pediatrics, Div. of Neonatology, Baylor College of Medicine, Houston, TX

9:30-9:45

35

IMPACT OF AMNIONITIS AND ANTEPARTUM ANTIBIOTIC TREATMENT ON NEONATAL OUTCOME AFTER pPROM

Beazlev D. NICHD-MFMU Network, Bethesda, MD

9:45-10:00

36

COST EFFECTIVE DELIVERY MANAGEMENT OF THE VERTEX/NON-VERTEX TWIN GESTATION

Mauldin JG. Newman RB, Durkalski VL, Mauldin PD, Dept. Ob/Gyn, Medical University of South Carolina, Charleston, SC

Friday, February 6, 1998 I

.....

1:00 p.m. to 3:30 p.m.

Oral Concurrent Session C

Fontainebleau Ballroom A/B

Prematurity Infectious Disease Moderators: Jay D. Iams, MD Robert L. Goldenberg, MD 1:00-1:15

37

SPONTANEOUS PRETERM PARTURITION IS PRECEDED BY AN ELEVATION IN FETAL PLASMA CORT1SOL

Yoon Bfl, Romero R. Park KH, Choi ST, Chang JW, Park JS, Jun JK, Dept Ob/Gyn, Seoul National University, Seoul, Korea

1:15-1:30

38

PCR GENE AMPLIFICATION OF BACTERIAL 16St RNA GENE IN THE DETECTON OF INRAAMNIOTIC INFECTION AND PREDICTION OF PRETERM DELIVERY

.Qvarzun E, Yamamoto M, Kato S, Lizama L, Moenne A, Perinatal Medicine Unit, Pontificia Unlversidad Cat61ica de Chile, Bioscan S.A., Santiago, Chile

1:30-1:45

39

RES ULTS OF A PROSPECTIVE, B LINDED, MULTICENTER TRIAL OF SALIVARY ESTRIOL FOR RISK OF PRETERM LABOR AND DELIVERY

~ H e i n e P, Artal R, Dullien V, Hastir,gs C, Goodwin TM, Hayashi R, lares J, Robertson P, Jackson M, Vamer M, Univ. of CO; Univ. of Pitt.; SUNY; Biex, Inc.; USC; Univ. of MI; Ohio State Univ.; UCSF; and Univ. of Utah

XVIII

January 1998

American Journal of Obstetrics and Gynecology

1:45-2:00

40

BETA-HCG IN CERVICAL/VAGINALSECRETIONS AS A PREDICTOR FOR PRETERM DELIVERY

Bertzstr PS. Stem R, Lin N, Furgtuele J, Karmen A. Cometford-Freda M, Gitz B, Chazotte C, Dept. of Ob/Gyn, Women's Health and Lab. Medicine, Albert Einstein College of Medicine, Bronx, NY

2:00-2:15

41

THE EFFICACY OF MAINTENANCE THERAPY AFTER ACUTE TOCOLYSIS: A META-ANALYSIS

Sonchez-Ramos L Wears RL, Gandier FL, Delke L Kamzitz AM, Dept. of OblGyn, Univ. of Florida, Jacksonville, FL.

2:15-2:30

42

TERBUTALINE PUMP FOR PREVENTION OF PRETERM DELIVERY: A DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL

GIdmt DA, Goepfert AR, Owen J, Wenstrom KD, Hauth JC, Univ. of Alabama at Birmingham, Birmingham, AL

2:30-2:45

43

A RANDOMIZED CONTROLLED TRIAL OF ORAL AND INTRAMUSCULAR DEXAMETHASONE IN THE PREVENTION OF NEONATAL RESPIRATORY DISTRESS SYNDROME

Eeerman RS. Mercer B, Doss JL. Sibai BM, Dept. of Ob/Gyn., Univ. of Tennessee, Memphis, TN

2:45-3:00

44

OBSTETRICAL INFECTION RATES UNDER THREE DIFFERENT PROTOCOLS FOR PREVENTION OF GROUP B STREPTOCOCCAL INFECTION

Locksmith GJ. Duff P, Dept. of Ob/Gyn, Univ. of Florida, Gainesville, FL

3:00-3:15

45

POTENTIAL CONSEQUENCES OF WIDESPREAD ANTEPARTUM AMPICILLIN USAGE

Towers CV Carr MH, Padilla L, Asrat T, Long Beach Memorial Women's Hospital, Long Beach, CA; Univ. of California at Irvine, Orange, CA

3:15-3:30

46

EFFECTS OF ANGIOGENIC GROWTH FACTORS ON UTERINE AND PLACENTAL ARTERY ENDOTHELIAL PROSTACYCLIN PRODUCTION

Krishnamurthv P. Bird IM, Sheppard C, Magness RR, Perinatal Rese,'u'chLabs, Dept. Ob/Gyn, Univ. of Wisconsin, Madison, WI

Friday, February 6, 1998 i

l:00 p.m. to 3:30 p.m.

Oral Concurrent Session D

'

Fontainebleau Ballroom C/D

Genetics Ultrasound Moderators: Larry C. Gilstap III, MD Katharine D. Wenstrom, MD 1:00-1:15

47

TRISOMY 21 MULTICENTER COLLABORATIVE PROJECT

Persutte WH. Hobbins JC, Nyberg DA, Bahado-Singh R, Hill LM, Abuhamad A, Vintzileos AM, Platt L, Benacerraf B, and the other participants, UCHSC, Denver, CO

1:15-1:30

48

FIRST TRIMESTER DOWN SYNDROME SCREENING

~Kr#AtR..12~HallahanT, Orlandi E Rossi C, Larsen J, Buchanan P, Macri J, NTD Laboratories, Inc. Huntington Station, NY.; Centro Di Diagnosi Prenatale, Palermo, Italy; George Washington Univ. Med. Center, Washington, D.C.; GeneCare Medical Genetics Center, Chapel Hill, NC

1:30-1:45

49

COMBINED URINE AND ULTRASOUND SCREENING: A NEW ALTERNATIVE TO ROUTINE GENETIC AMNIOCENTESIS IN WOMEN _>35

Bahado-~qhzgh R, Oz U, Kovanchi E, CetTnik D, Stiller R, Flores D, Copel J, Mahoney M J, Cole L, Dept. of Ob/Gyn, Yale University, New Haven, CT; Bridgeport Hospital, Bridgeport, CT

1:45-2:00

50

CEMAT (CANADIAN EARLY (EA) VS. MIDTRIMESTER (MA) AMNIOCENTESIS TRIAL) PROSPECTIVE RANDOMIZED EVALUATION: AMNIOCENTESIS PROCEDURE DETAILS

Johnson .IM. Wilson RD, CEMAT Group

American Journal of Obstetrics and Gynecology

January 1998 XIX

2:00-2:15

51

THE INFLUENCE OF 5' 10 METHYLENETETRAHYDROFOLATE REDUCTASE GENOTYPES ON ENZYME ACTIVITY IN PLACENTAL TIS SUE

Dal_v S. Molloy A, Mills J, Lee Y, Conley M, Eb'ke P, Web"D, Scott.f, Dept. of Ob/Gyn, Jefferson Medical College of Thomas Jefferson Univ., Philadelphia, PA; Depts. of Clinical Med. and Biochemistry, Trinity College Dublin, h'eland; Health Research Board, Dublin, heland; and Branches of Epidemiology and Biometry, NICHD/NIH, Bethesda, MD

2:15-2:30

52

DEVELOPMENT OF AN ALLELE-SPECIFIC POLYMERASE CHAIN REACTION ASSAY FOR PRENATALGENOTYPING OF Jka and Jkb OF THE KIDD BLOOD GROUP SYSTEM

Her MJ. Pircon RA, Lut,m RA, The Blood Center of Southeastern Wisconsin; The Medical College of Wisconsin, Milwaukeee, WI

2:30-2:45

53

MAIN SPLENIC ARTERY DOPPLER: A STRONG PREDICTOR OF SEVERE FETAL ANEMIA IN RH ALLIMUNIZATION

Bahado-$#z~h R. Oz U, Deren O, Copel J, Pirhonen J, Kovanci E, Ondetoglu L, Dept. of Ob/Gyn, Yale University, New Haven, CT

2:45-3:00

54

PRENATALDIAGNOSIS OF A "LEAN" UMBILICAL CORD: AN EARLY AND SIMPLE MARKER FOR THE FETUS AT RISK FOR SGA AT BIRTH

lla].O_l~Ghezzi F, Di Naro E, Gomez R, Maymon E, Mueller M, Dept. of Ob/Gyn, Kantoaspital, Munsterlingen, Switzerland

3:00-3:15

55

EXAMINATION OF FETAL CORONARY BLOOD FLOW PREDICTS PERINATAL OUTCOME IN INTRAUTERINE GROWTH RESTRICTION

Baschat AA. Kramer WB, Weiner CP, Gembnwh U, Dept. of Ob/Gyn and Reprod. Sciences, Univ. of Maryland, Baltimore, MD; Dept. of Ob/Gyn, Medical Univ., Lilbeck, Germany

3:15-3:30

56

THE BENEFITS OF PERINATOLOGIST-PERFORMED PRENATALULTRASOUND

Berdi , f ~ e r n s t e i n PS, Divon MY Dept. of Ob/Gyn, Albert Einstein College or Medicine, Bronx, NY

Saturday, February7, 1998 8:00 a.m. to 10:30 a.m.

Oral Concurrent Session E

Fontainebleau Ballroom A/B

Prenatal Diagnosis Fetal Therapy Moderators: IsabelleA. Wilkins, MD Mark Evans, MD Charles Kleinman, MD, 1998 Honorary Member 800-8:15

57

CERVICAL LENGTH ASSESSMENT: A USEFUL ADDITION TO THE SCREENING OBSTETRICAL ULTRASOUND EXAMINATION

Smith RS. Comstock CH, Kb'k JS, Brodsky B, Tatem G, Lee W, Division of Fetal Imaging, Dept. of Ob/Gyn, William Beaumont Hospital, Royal Oak. Michigan and Dept. of Ob/Gyn, Wayne State Univ., Detroil, MI

8:[5-8:30

58

MULTICENTER INTERNATIONAL ASSESSMENT - 142,367 PRENATALKARYOTYPES, CHROMOSOMAL SPECIFIC PROBES (CSP), AND FLUORESCENT IN S]TU HYBRIDIZATION (FISH) LIMITATIONS

Evc~rLrMI, Hemy GP,, Miller W, Bui T-H. Snijders R, Wapner RJ, Miny 1o, Johnson MP, Peakman D, Johnson A, Nicolaides K, Holzgreve W, Ebrahim SA, Babu R, Jackson L, Depts. of Ob/Gyn, Molecular Medicine & Genetics, and Pathology, Wayne State Univ., Detroit, MI; Reproductive Genetics Center, Denver, CO; Prenatal Diagnosis Center, Lexington, MA; Karolinska Institute, Stockholm, Sweden; Kings College, London, England; Jefferson Medical College, Philadelphia, PA; Univ. of Basel, Basel, Switzerland; Quest/Nichols,Inc., CA

8:30-8:45

59

ELECTROSPRAY MASS SPECTROMETRY OF PCR PRODUCTS: A POWERFUL NEW TECHNIQUE FOR GENETIC SCREENING AND MUTATION DETECTION

NeLson CLNelson L, Ward K, Depts. of Human Genetics and Ob/Gyn, Univ. of Utah, Salt Lake City, UT

XX

January 1998

American Journal of Obstetrics and Gynecology

8:45-9:00

60

CEMAT (CANADIAN EARLY (EA) VS. MIDTRIMESTER (MA) AMNIOCENTESIS TRIAL) PROSPECTIVE RANDOMIZED EVALUATION: COMPARISON OF AMNIOTIC FLUID CULTURE CHARACTERISTICS BETWEEN EAAND MA

Winsor EJT. Wi&on RD, CEMAT Group

9:00-9:15

61

EFFICACY OF ULTRASOUND FOR PRENATAL DIAGNOSIS OF OPEN NEURAL TUBE AND VENTRAL WALL DEFECTS

Lennon C. Gray D, Dept. of Ob/Gyn, Washington Univ. School of Medicine, St. Louis, MO

9:15-9:30

62

ANTENATAL SONOGRAPHIC DETECTION OF FETAL HYDRONEPHROSIS AS A PREDICTOR OF POSTNATAL HYDRONEPHROSIS

Bonebrake R. Fleming A, Dutton K, Dept. of Ob/Gyn, Creighton Univ. School of Medicine, Omaha, NE

9:30-9:45

63

MULTICENTER EXPERIENCE OF FETAL BLADDER SHUNTS

Din,is G. Daly SF, Yang J, Kaufmalm M., Wapner RJ, Dept. of Ob/Gyn, Jefferson Medical College of Thomas Jefferson Univ., Phil., PA

9:45-10:00

64

DEREGULATED EXPRESSION OF THE eyr61 IMMEDIATEEARLY-GENE IN CONGENIC MICE : A MODEL FOR THE STUDY OF GENETIC REGULATORS OF INTRAUTERINE GROWTH

Santolava-Foreas J. Koures A, Lau L, Depts of Ob/Gyn and Genetics, Univ. of Illinois, Chicago, IL

10:00-10:15

65

AMNIOREDUCTION IN TWIN-TWIN TRANSFUSION SYNDROME - A MULTICENTER REGISTRY, EVALUATION OF 579 PROCEDURES

Mari G. International TTS Registry Group, Maternal Fetal Medicine, Yale University, New Haven, CT

10:15-10:30

66

OPEN FETAL SURGERY FOR CONGENITAL CYSTIC ADENOMATOID MALFORMATION OF THE LUNG

Adzick S. Harrison M, Crombleholme T, Flake A, Howell L, Children's Hospital of Philadelphia, Phil., PA; Univ. of California, San Francisco, CA

Saturday, February 7, 1998 8:00 a.m. to 10:30 a.m.

Oral Concurrent Session F

Fontainebleau Ballroom C/D

Clinical Obstetrics Medical Complications of Pregnancy Moderators:

Valerie M. Parisi, MD Thomas J. Benedetti, MD

800-8:15

67

PRELABOR RUTURE OF THE MEMBRANES (PROM) AT TERM: EXPECTANT MANAGEMENT AT HOME VS. IN HOSPITAL

Di Cecco R. Hannah M, Hodnett E, Foster G, Farine D, Helewa M, Dept. of Ob/Gyn and Maternal Infant and Reproductive HRU, CRWH, Univ. of Toronto and Univ. of Manitoba, Canada

8:15-8:30

68

CERVICAL RIPENING AND LABOR INDUCTION: MISOPROSTOL VS. DINOPROSTONE

~lark A, Cook V, Hill P, Spinnato J, Dept. of Ob/Gyn, Univ. of Louisville, Louisville, KY

8:30-8:45

69

MEMBRANE STRIPPING VS DINOPROSTONE VAGINAL INSERT IN THE MANAGEMENT OF PREGNANCIES BEYOND 41 WEEKS WITH AN UNFAVORABLE CERVIX

Maeann EE Chauhan SP, McNamara ME Bass JD, Estes CM, Morrison JC, Dept. of Ob/Gyn, Univ. of Mississippi, Jackson, MS; Dept. of Ob/Gyn, Medical College of Georgia, Augusta, GA; Dept. of Ob/Gyn, Naval Medical Center, San Diego, CA

8:45-9:00

70

RANDOMIZED, DOUBLE-BLINDED TRIAL OF OXYTOCIN USE FOR INDUCTION OF LABOR

Merrill D. Zlatnik E Dept. of Ob/Gyn, University of Iowa, Iowa City, IA

9:00-9:15

71

A RANDOMIZED CLINICAL TRIAL OF TWO SURGICAL TECHNIQUES FOR CESAREAN SECTION

Franchi M. Ghezzi E Balestrerl D, Miglierina M, Zanaboni E Donadello N, Bolis PE Dept. of Ob/Gyn, University of Varese, Varese, Italy

American Journal of Obstetrics and Gynecology

January 1998 XXl

9:15-9:30

72

IS VBAC LESS EXPENSIVE THAN REPEAT CESAREAN?

Clr SI~ McClellan V, Scott JR, Burton DA, Porter TF,,Intermountain Health Care and University of Utah, S,'tit Lake City, UT

9:30-9:45

73

TIMING OF DELIVERYAND NEONATAL OUTCOME IN PATIENTS WITH CLINICALLY OVERT UTERINE RUPTURE DURING VBAC

Porter TE Clark SL, Esplin MS, Tooke-Miller C, Scott JR, Dept. of Ob/Gyn, Univ. of Utah, Salt Lake City, UT

9:45-10:00

74

300 TERM BRAIN DAMAGED INFANTS: THEIR FHR PATTERNS

Phelan JP, Ahn MO, Dept. of Ob/Gyn, Pomona Valley Hospital Medical Center, Pomona, CA; Cha Women's Hospital, Seoul, Korea; Childbirth Injury Prevention Foundation, Pasadena, CA

10:00-10:15

75

THE EFFECT OF SECOND VAGINAL DELIVERY ON ANORECTAL PHYSIOLOGY AND FECAL CONTINENCE

Fvnes M, Donnelly V, Behan M. O'Herlihy C, O'ConneU PR, Depts. of Ob/Gyn, Surgery and Radiology, University College Dublin, Ireland

10:15-10:30

76

PROTEINURIA AND ADVERSE PREGNANCY OUTCOME IN WOMEN WITH CHRONIC HYPERTENSION

Sibai BM, NICHD MFMU Network, Bethesda, MD

XXll

January 1998

American Journal of Obstetrics and Gynecology