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Subject index volume 3 (1975)
T O X I C O L OG Y
SUBJECT INDEX Volume 3 (1975)
Acetylsalicylic acid, prenatal administration in rats, 207 Additive, growth-promoting, for pigs, 369 Aerosol propellants, classification, 321 --, toxicity, in respiratory and circulatory systems, 79, 213, 225, 241, 311, 321 Aflatoxin B1, comparative histopathological effects, 177 Alcohol sulphate, teratogenic and embryotoxic activity, 91 Alkylbenzene sulphonate, teratogenic and embryotoxic activity, 91 Amaranth, dietary, long-term effects in rats, 115, 129 --, effect on foetal development in rats, 129 --, effect on reproduction in rats, 115 Aminotriazole, labelled, distribution in mice, 49 Anaesthesia, rats, influence on action of aerosol propellants, 225 Animal feeds, additives to, toxicity of, 361, 369 Animals, growth-promoting food additives, 3 Announcement, Health Effects of Chemicals in Foods, 265 --, 3rd Intern. Syrup. on Mass Spectrometry in Biochemistry and Medicine, 266 Blood, affinity for CO, 301 --, storage in glass or plastic bottles, 87 Bromide, excretion in the rat, influence of dietary chloride, 29 Carbadox, safety to human consumers, 369 Carbon monoxide, uptake in blood of miniature pigs, 301 Cardiac lesions in the rat, influence of aerosol propellants, 213 Cardiodepressant action, of aerosols, 79 Chick embryo, toxicity of aflatoxin and palmotoxin, 177 Chloride, dietary, influence on bromide excretion in the rat, 29 Chlormadinone acetate, growth-promoting additive, 3
Chlorodioxins, toxicity, 187 Chromosomal abnormalities, in irradiated cultured lymphocytes, 87 Circulatory system, toxicity of aerosol propellants, 79, 213, 225, 241, 311, 321 Classification, of aerosol propellants, 321 CLD, commercial light duty detergent, teratogenic and embryotoxic activity, 91 Diethylstilboestrol, growth-promoting additive, 3 2,3-Dihydro-3-oxobenzisosulphonazole, (saccharin), metabolism in animals, 287 Dimethyl sulphoxide, (DMSO), toxicity, 143 Disodium 5'-ribonucleotide, effect on reproductive function of rat, 333 --, long-term feeding study in dogs, 341 Dog, toxicity of dimethyl sulphoxide, 143 --, ventricular function, influence of aerosol propellants, 79 Dogs, long-term feeding study on disodium 5'-ribonucleotide, 341 Editorial, 1, 141, 267 Enzyme activity, in rat-liver mitochondria, influence of sporofusarin, 69 Estradiol benzoate, growth-promoting implant, 3 Estradiol monopalmitate, growth-promoting implant, 3 FC 11, trichlorofluoromethane, acute inhalational toxicity, 311 Feed additives, for animals, toxicity to man, 361, 369 Food additives, animals, growth-promoting, 3 Food plants, toxicological implications of pesticides, 269 F u s a r i u m sporotrichiella, sporofusarin, 69 Gallus d o m e s t i c u s , embryo, toxicity of aflatoxin and palmotoxins, 177
399
Germicide, Irgasan DP300, percutaneous absorption and metabolism, 33 5'-Guanylate, disodium, feeding study in dogs, 341 Hamsters, affinity of blood for CO, 301 Herbicide, aminotriazole, distribution in mice, 49 Herbicides, short-term oral and dermal toxicity, 349 Hormone products, growth-promoting additives to animal food, 3 2-Hydroxy- 2' 4, 4'-trichlorodiphenyl ethyl, (Irgasan DP300), percutaneous absorption and metabolism, 33 5'-Inosinate, disodium, feeding study in dogs, 341 Irgasan DP300, percutaneous absorption and metabolism, 33 Mecoprop, oral and dermal toxicity in rats, 349 Medroxyprogesterone acetate, growthpromoting additive, 3 Melengestrol acetate, ~owth-promoting additive, 3 Mercury, tissue concentrations in squirrel monkeys, 171 2-(2-Methyl-4-chlorophenoxy)propionic acid, oral and dermal toxicity in rats, 349 2-Methyl-4-chlorophenoxyacetic acid, oral and dermal toxicity in rats, 349 MCPA, short-term oral and dermal toxicity, 349 MCPP, short-term oral and dermal toxicity, 349 Mice, distribution of labelled anainotriazole in, 49 Nitrosoproline[l 4 C], absorption, distribution and excretion by rats, 23 a-Olefin sulphonate, teratogenic and embryotoxic activity, 107 Palmotoxins, comparative histopathological effects, 177 Pesticides, chlorodioxins, 187 --, toxicological implications, 269 Pig, toxicity of dimethyl sulphoxide, 143 Pigs, affinity of blood for CO, 301 --, growth-promoting additive, safety to human consumers, 369
400
Polychlorodibenzo-p-dioxins, 187 Primates, respiration and circulation toxicity of aerosol propellants, 241 Pulmonary emphysema, rats, influence ol action of aerosol propellants, 225 Pulmonary vascular lesions in the rat, in fluence of aerosol propellants, 213 Purine synthesis, possible influenee o aminotriazole, 49 [(Quinoxalinyl-2-dioxide-1,4)-methylene]3-methylcarbazate N 1,N4-dioxide, growth-promoting additive for pigs 369 Rabbit, toxicity of dimethyl sulphoxide 143 Rabbits, affinity of blood for CO, 301 Rat, bromide excretion, influence o dietary chloride, 29 --, cardiac and pulmonary vascular le sions, influence of aerosol propellants 213 --, pulmonary emphysema and anaesthe sia, influence on action of aeroso propellants, 225 --, reproductive function, effect of diso dium 5'-ribonucleotide, 333 --, toxicity of dimethyl sulphoxide, 14[ Rats, absorption, distribution and excre tion of [24 C]nitrosoproline, 23 --, affinity of blood for CO, 301 --, long-term effects of dietary amaranth 115, 129 --, prenatal administration of acetylsali cylic acid, 207 --, short-term oral and dermal toxicity o herbicides, 349 --, with lesions, influence of aerosol pro pellants, 213, 225 Respiratory system, toxicity of aeroso propellants, 79, 213, 225, 241, 311 321 5'-Ribonucieotide, disodium, effect or reproductive function of rat, 333 , , long-term feeding study in dogs 341 Ribotide, 333, 341 Saccharin, metabolism in animals, 287 Seed germination, toxic effects of pesticides, 269 Skin, deposition and penetration of trichlorocarbanilide, 253 Soap, with Irgasan DP300, 33
--, with trichlorocarbanilide, 253 Sodium ethylmercurithiosalicylate, tissue concentrations of Hg in squirrel monkeys, 171 Sporofusarin, influence on enzyme activity in rat-liver mitochondria, 69 Squirrel monkeys, tissue concentrations of Hg, 17 Steroid products, growth-promoting additives to animal food, 3 Surfactants, teratogenic potential, 91, 107
Thiomersal, tissue concentrations of Hg in squirrel monkeys, 171 Toxicity by relay, 361, 369 Trichlorocarbanilide, skin deposition and penetration, 253 Trichlorofluoromethane, acute inhalational toxicity, 311 Ventricular function in the dog, influence of aerosol propellants, 79 Zeranol, growth-promoting implant, 3
401
SUBJECT INDEX Volume 3 (1975)
Acetylsalicylic acid, prenatal administration in rats, 207 Additive, growth-promoting, for pigs, 369 Aerosol propellants, classification, 321 --, toxicity, in respiratory and circulatory systems, 79, 213, 225, 241, 311, 321 Aflatoxin B1, comparative histopathological effects, 177 Alcohol sulphate, teratogenic and embryotoxic activity, 91 Alkylbenzene sulphonate, teratogenic and embryotoxic activity, 91 Amaranth, dietary, long-term effects in rats, 115, 129 --, effect on foetal development in rats, 129 --, effect on reproduction in rats, 115 Aminotriazole, labelled, distribution in mice, 49 Anaesthesia, rats, influence on action of aerosol propellants, 225 Animal feeds, additives to, toxicity of, 361, 369 Animals, growth-promoting food additives, 3 Announcement, Health Effects of Chemicals in Foods, 265 --, 3rd Intern. Syrup. on Mass Spectrometry in Biochemistry and Medicine, 266 Blood, affinity for CO, 301 --, storage in glass or plastic bottles, 87 Bromide, excretion in the rat, influence of dietary chloride, 29 Carbadox, safety to human consumers, 369 Carbon monoxide, uptake in blood of miniature pigs, 301 Cardiac lesions in the rat, influence of aerosol propellants, 213 Cardiodepressant action, of aerosols, 79 Chick embryo, toxicity of aflatoxin and palmotoxin, 177 Chloride, dietary, influence on bromide excretion in the rat, 29 Chlormadinone acetate, growth-promoting additive, 3
Chlorodioxins, toxicity, 187 Chromosomal abnormalities, in irradiated cultured lymphocytes, 87 Circulatory system, toxicity of aerosol propellants, 79, 213, 225, 241, 311, 321 Classification, of aerosol propellants, 321 CLD, commercial light duty detergent, teratogenic and embryotoxic activity, 91 Diethylstilboestrol, growth-promoting additive, 3 2,3-Dihydro-3-oxobenzisosulphonazole, (saccharin), metabolism in animals, 287 Dimethyl sulphoxide, (DMSO), toxicity, 143 Disodium 5'-ribonucleotide, effect on reproductive function of rat, 333 --, long-term feeding study in dogs, 341 Dog, toxicity of dimethyl sulphoxide, 143 --, ventricular function, influence of aerosol propellants, 79 Dogs, long-term feeding study on disodium 5'-ribonucleotide, 341 Editorial, 1, 141, 267 Enzyme activity, in rat-liver mitochondria, influence of sporofusarin, 69 Estradiol benzoate, growth-promoting implant, 3 Estradiol monopalmitate, growth-promoting implant, 3 FC 11, trichlorofluoromethane, acute inhalational toxicity, 311 Feed additives, for animals, toxicity to man, 361, 369 Food additives, animals, growth-promoting, 3 Food plants, toxicological implications of pesticides, 269 F u s a r i u m sporotrichiella, sporofusarin, 69 Gallus d o m e s t i c u s , embryo, toxicity of aflatoxin and palmotoxins, 177
399
Germicide, Irgasan DP300, percutaneous absorption and metabolism, 33 5'-Guanylate, disodium, feeding study in dogs, 341 Hamsters, affinity of blood for CO, 301 Herbicide, aminotriazole, distribution in mice, 49 Herbicides, short-term oral and dermal toxicity, 349 Hormone products, growth-promoting additives to animal food, 3 2-Hydroxy- 2' 4, 4'-trichlorodiphenyl ethyl, (Irgasan DP300), percutaneous absorption and metabolism, 33 5'-Inosinate, disodium, feeding study in dogs, 341 Irgasan DP300, percutaneous absorption and metabolism, 33 Mecoprop, oral and dermal toxicity in rats, 349 Medroxyprogesterone acetate, growthpromoting additive, 3 Melengestrol acetate, ~owth-promoting additive, 3 Mercury, tissue concentrations in squirrel monkeys, 171 2-(2-Methyl-4-chlorophenoxy)propionic acid, oral and dermal toxicity in rats, 349 2-Methyl-4-chlorophenoxyacetic acid, oral and dermal toxicity in rats, 349 MCPA, short-term oral and dermal toxicity, 349 MCPP, short-term oral and dermal toxicity, 349 Mice, distribution of labelled anainotriazole in, 49 Nitrosoproline[l 4 C], absorption, distribution and excretion by rats, 23 a-Olefin sulphonate, teratogenic and embryotoxic activity, 107 Palmotoxins, comparative histopathological effects, 177 Pesticides, chlorodioxins, 187 --, toxicological implications, 269 Pig, toxicity of dimethyl sulphoxide, 143 Pigs, affinity of blood for CO, 301 --, growth-promoting additive, safety to human consumers, 369
400
Polychlorodibenzo-p-dioxins, 187 Primates, respiration and circulation toxicity of aerosol propellants, 241 Pulmonary emphysema, rats, influence ol action of aerosol propellants, 225 Pulmonary vascular lesions in the rat, in fluence of aerosol propellants, 213 Purine synthesis, possible influenee o aminotriazole, 49 [(Quinoxalinyl-2-dioxide-1,4)-methylene]3-methylcarbazate N 1,N4-dioxide, growth-promoting additive for pigs 369 Rabbit, toxicity of dimethyl sulphoxide 143 Rabbits, affinity of blood for CO, 301 Rat, bromide excretion, influence o dietary chloride, 29 --, cardiac and pulmonary vascular le sions, influence of aerosol propellants 213 --, pulmonary emphysema and anaesthe sia, influence on action of aeroso propellants, 225 --, reproductive function, effect of diso dium 5'-ribonucleotide, 333 --, toxicity of dimethyl sulphoxide, 14[ Rats, absorption, distribution and excre tion of [24 C]nitrosoproline, 23 --, affinity of blood for CO, 301 --, long-term effects of dietary amaranth 115, 129 --, prenatal administration of acetylsali cylic acid, 207 --, short-term oral and dermal toxicity o herbicides, 349 --, with lesions, influence of aerosol pro pellants, 213, 225 Respiratory system, toxicity of aeroso propellants, 79, 213, 225, 241, 311 321 5'-Ribonucieotide, disodium, effect or reproductive function of rat, 333 , , long-term feeding study in dogs 341 Ribotide, 333, 341 Saccharin, metabolism in animals, 287 Seed germination, toxic effects of pesticides, 269 Skin, deposition and penetration of trichlorocarbanilide, 253 Soap, with Irgasan DP300, 33
--, with trichlorocarbanilide, 253 Sodium ethylmercurithiosalicylate, tissue concentrations of Hg in squirrel monkeys, 171 Sporofusarin, influence on enzyme activity in rat-liver mitochondria, 69 Squirrel monkeys, tissue concentrations of Hg, 17 Steroid products, growth-promoting additives to animal food, 3 Surfactants, teratogenic potential, 91, 107
Thiomersal, tissue concentrations of Hg in squirrel monkeys, 171 Toxicity by relay, 361, 369 Trichlorocarbanilide, skin deposition and penetration, 253 Trichlorofluoromethane, acute inhalational toxicity, 311 Ventricular function in the dog, influence of aerosol propellants, 79 Zeranol, growth-promoting implant, 3
401