Subject index—volume 117

SUBJECT INDEX—VOLUME 117 APM ⫽ APM Views article; BO ⫽ Brief Observation; E ⫽ Editorial; LE ⫽ Letter to the editor; R ⫽ Review

ABDOMINAL AORTIC ANEURYSMS Mycotic Aneurysms of the Abdominal Aorta (LE), 208 ABDOMINAL CT SCAN Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193 ABSCESS Low Sensitivity of Ultrasonography for the Early Diagnosis of Amebic Liver Abscess (BO), 519 ACCESS Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479 ACCREDITATION The Association of Program Directors in Internal Medicine: Promoting Excellence in Internal Medicine Graduate Medical Education (APM), 894 ACETYLCYSTEINE Has Acetylcysteine Use Changed the Incidence of Contrast Nephropathy in Hospitalized Patients? A Before-After Study (BO), 948 Is Acetylcysteine Effective in Preventing Contrast-Related Nephropathy? A Metaanalysis (R), 938 ACTIVITIES OF DAILY LIVING The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484 ACUTE CORONARY SYNDROME Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Patient Adherence: The Next Frontier in Quality Improvement (E), 130 ACUTE CORONARY SYNDROMES Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963 ADENOMATOUS POLYPS Systematic Reviews of Herbal Medicines (LE), 533 © 2004 by Elsevier Inc. All rights reserved.

ADHERENCE Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 Clinician Awareness of Adherence to Hypertension Guidelines, 747 Patient Adherence: The Next Frontier in Quality Improvement (E), 130

ALCOHOL Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709 Uncomplicated Alcohol Intoxication in the Emergency Department: An Analysis of the National Hospital Ambulatory Medical Care Survey (BO), 863 ALFACALCIDOL Comparative Efficacy of Hormone Replacement Therapy, Etidronate, Calcitonin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549

ADMINISTRATORS Role of Administrators of Internal Medicine in Improving Departments of Internal Medicine (APM), 626

ALUMINUM Aluminum in Antiperspirants: More Than Just Skin Deep (E), 969

ADULT PHENYLKETONURIA Adult Phenylketonuria (R), 590

Hyperaluminemia in a Woman Using an Aluminum-containing Antiperspirant for 4 Years (BO), 956

The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615 ADVERSE EVENTS Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 AGE-RELATED DIFFERENCES The Net Transfer Organs across Race, Sex, Age, and Income, 670 Sex- and Age-Related Differences in the Prognostic Value of C-Reactive Protein in Patients with Angiographic Coronary Artery Disease, 657 AGENCY FOR HEALTH CARE RESEARCH AND QUALITY The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213

ALZHEIMER DISEASE Aluminum in Antiperspirants: More Than Just Skin Deep (E), 969 AMEBIC LIVER ABSCESS Low Sensitivity of Ultrasonography for the Early Diagnosis of Amebic Liver Abscess (BO), 519 AMENORRHEA Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966 ANALBUMINEMIA Treatment of Severe Hypercholesterolemia with Atorvastatin in Congenital Analbuminemia (LE), 803 ANEMIA Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193

AGING Genes, Rates of Aging, and Duration of Human Life (E), 882

ANEURYSMS Cases from the Osler Medical Service at Johns Hopkins University (IO), 196

The Genetics of Human Longevity (R), 851

Mycotic Aneurysms of the Abdominal Aorta (LE), 208 0002-9343/04/$–see front matter 985

Subject Index

Pulmonary Artery Aneurysms in Behc¸et Syndrome (BO), 867 Unilateral Transudative Pleural Effusion: An Exceptional Cause (LE), 888 ANGINA Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963 Bedside Diagnosis of Coronary Artery Disease: A Systematic Review (R), 334 Prognostic Importance of Presenting Symptoms in Patients Undergoing Exercise Testing for Evaluation of Known or Suspected Coronary Disease, 380 Prognostic Value of Quantitative Troponin T Measurements in Unstable Angina/ Non-ST-Segment Elevation Acute Myocardial Infarction Treated Early and Predominantly with Percutaneous Coronary Intervention, 897 Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145 Suboptimal Pharmacotherapeutic Management of Chronic Stable Angina in the Primary Care Setting, 234 Temporal Trends in the Incidence of Coronary Disease, 228 ANGIOGRAPHY Has Acetylcysteine Use Changed the Incidence of Contrast Nephropathy in Hospitalized Patients? A Before-After Study (BO), 948 Is Acetylcysteine Effective in Preventing Contrast-Related Nephropathy? A Metaanalysis (R), 938 Routine Screening Angiography of Extracardiac Arteries During Cardiac Catheterization: Angiographer’s Delirium or Common Sense? (LE), 443 ANGIOTENSIN-CONVERTING ENZYME INHIBITORS Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Identifying Gaps Between Guidelines and Clinical Practice in the Evaluation and Treatment of Patients with Hypertension, 14 986

December 15, 2004

ANGIOTENSIN RECEPTOR BLOCKS Spironolactone and Angiotensin Receptor Blocker in Nondiabetic Renal Diseases (LE), 444

ANTITHROMBOTIC THERAPY Benefits of Antithrombotic Therapy After Infrainguinal Bypass Grafting: A MetaAnalysis, 93

ANTI-TUMOR NECROSIS FACTOR Rheumatoid Arthritis and Heart Failure (LE), 709

ANXIETY Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719

ANTIDEPRESSANTS Antidepressants and Risk of First-Time Hospitalization for Myocardial Infarction: A Population-Based Case-control Study, 732 ANTIFIBROTIC AGENTS Hepatitis C Treatment Update, 344 ANTIHYPERTENSIVES Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709 Hypertension Control Rates: Time for Translation of Guidelines into Clinical Practice (E), 62 Identifying Gaps Between Guidelines and Clinical Practice in the Evaluation and Treatment of Patients with Hypertension, 14 ANTIMICROBIAL THERAPY Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726 ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIDES The Antineutrophil Cytoplasmic Antibody-Associated Vasculitides (R), 39 ANTIPERSPIRANT Aluminum in Antiperspirants: More Than Just Skin Deep (E), 969 Hyperaluminemia in a Woman Using an Aluminum-containing Antiperspirant for 4 Years (BO), 957 ANTIRHEUMATIC DRUGS Newer Disease-Modifying Antirheumatic Drugs and the Risk of Serious Hepatic Adverse Events in Patients with Rheumatoid Arthritis, 87

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Reducing PSAnxiety: The Importance of Noninvasive Chronic Disease Management in Prostate Cancer Detection and Treatment (E), 796 AORTIC ANEURYSM Unilateral Transudative Pleural Effusion: An Exceptional Cause (LE), 888 AORTITIS 25-Year Follow-up of a Case of Giant Cell Aortitis (LE), 625 APLASIA Pure Red Cell Aplasia Following Pegylated Interferon ␣ Treatment (LE), 619 APNEA Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 ARRHYTHMIAS Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 Magnesium Prophylaxis for Arrhythmias after Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials, 325 ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Presentation, Diagnosis, and Management, 685 ARTERIAL ENDOTHELIAL ACTIVATION C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499 ARTHRITIS Rheumatoid Arthritis and Heart Failure (LE), 709

Subject Index

ASCARIASIS The End of Wanderlust (LE), 66

Effects of Statins on Vascular Structure and Function: A Systematic Review, 775

ASCENDING AORTIC ANEURYSM Unilateral Transudative Pleural Effusion: An Exceptional Cause (LE), 888

ATORVASTATIN Treatment of Severe Hypercholesterolemia with Atorvastatin in Congenital Analbuminemia (LE), 803

ASEPTIC FAILURE Synovial Fluid Leukocyte Count and Differential for the Diagnosis of Prosthetic Knee Infection, 556 ASPIRIN Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 Do Aspirin and Nonsteroidal Anti-inflammatory Drugs Cause False-positive Fecal Occult Blood Test Results? A Prospective Study in a Cohort of Veterans, 837 Race, Region, and the Quest for Quality in Cardiovascular Care (E), 874 ASSOCIATION OF PROFESSORS OF MEDICINE Association of Professors of Medicine: Unifying Internal Medicine to Improve Health Care (APM), 974 ASTHMA Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479 ASYSTOLE Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 ATHEROSCLEROSIS C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499

ATRIAL DYSRHYTHMIAS Misdaignosis of Atrial Fibrillation and Its Clinical Consequences, 636 ATRIAL FIBRILLATION Misdaignosis of Atrial Fibrillation and Its Clinical Consequences, 636 Overreliance on Computerized Algorithms to Interpret Electrocardiograms (E), 706 ATRIOVENTRICULAR BLOCK Overreliance on Computerized Algorithms to Interpret Electrocardiograms (E), 706 AUTOIMMUNE HEPATITIS Reversibility of Cirrhosis in Autoimmune Hepatitis (BO), 125 AUTOIMMUNE THYROID DISEASES Hepatitis C and Thyroid Autoimmunity: Is There a Link? (E), 60 AUTONOMIC NERVOUS SYSTEM DYSFUNCTION Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome, 469 Cardiac Autonomic Dysfunction in Gulf War Syndrome: Veterans Hearts Don’t Rest at Night (E), 531 AUTOPSY RATE The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 AXILLARY MASS A Hydatid Cyst Presenting as an Axillary Mass (LE), 363 B-TYPE NATRIURETIC PEPTIDE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and ExerDecember 15, 2004

cise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 BACLOFEN Gabapentin for Intractable Hiccup (LE), 279 BACTERIAL ENDOCARDITIS The Lack of Diagnostic Value of the Indium Scan in Acute Bacterial Endocarditis (LE), 621 BACTERIAL PYOMYOSITIS Bacterial Pyomyositis in the United States (R), 420 BACTEROIDES UNIFORMIS Spontaneous Spondylodiscitis Caused by Bacteroides Uniforms, 284 BARIATRIC SURGERY Wernicke Encephalopathy—An Emerging Trend After Bariatric Surgery (LE), 804 BEDSIDE DIAGNOSIS Bedside Diagnosis of Coronary Artery Disease: A Systematic Review (R), 334 BEHC¸ET SYNDROME Pulmonary Artery Aneurysms in Behc¸et Syndrome (BO), 867 BETA-BLOCKERS Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Beta-blockers as Single-Agent Therapy for Hypertension and the Risk of Mortality among Patients with Chronic Obstructive Pulmonary Disease, 925 Suboptimal Pharmacotherapeutic Management of Chronic Stable Angina in the Primary Care Setting, 234

␤2ADRENERGIC AGONISTS Proposed Guidelines for Clenbuterol Food Poisoning (LE), 362 ␤-ADRENERGIC RECEPTORS Association of ␤-Adrenergic Receptor Polymorphisms and Progression to Heart Failure in Patients with Idiopathic Dilated Cardiomyopathy, 451

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Subject Index

Polymorphisms of ␤-adrenergic Receptors in Heart Failure (E), 525

BOARD CERTIFICATION The Future of Certification and Recertification (APM), 140

BIAS Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842

Modernizing the Paths to Certification in Internal Medicine and Its Subspecialties (E), 133

Commercial Support and Bias in Pharmaceutical Research (E), 876

BODY MASS INDEX Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738

BILBERRY Systematic Reviews of Herbal Medicines (LE), 533 BIOPSY Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719 BIRTH WEIGHT Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 BLEEDING Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 BLOOD PRESSURE Clinician Awareness of Adherence to Hypertension Guidelines, 747 Identifying Gaps Between Guidelines and Clinical Practice in the Evaluation and Treatment of Patients with Hypertension, 14

BODY WEIGHT Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738 Helicobacter pylori and Ghrelin: Interrelated Players in Body-weight Regulation? (E), 436 BONE MINERAL DENSITY Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 Characterization of Normocalcemic Primary Hyperparathyroidism (BO), 861

Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein Subfractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398 CALCITONIN Comparative Efficacy of Hormone Replacement Therapy, Etidronate, Calcitonin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549 CALCIUM Characterization of Normocalcemic Primary Hyperparathyroidism (BO), 861

Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966

The Further Evolution of Hyperparathryoidism: Implications for Clinical Care (E), 884

Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952 BRAIN NATRIURETIC PEPTIDE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA Solitary Nodular Form of Bronchiolitis Obliterans Organizing Pneumonia (LE), 887

Suberythemal Ultraviolet Exposure and Reduction in Blood Pressure (LE), 281 BLUNT CHEST TRAUMA Platypnea-Orthodeoxia Syndrome Occurring After a Blunt Chest Trauma with Acute Tricuspid Regurgitation (LE), 890

C-REACTIVE PROTEIN C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499

December 15, 2004

C-REACTIVE PROTEIN LEVELS Association of the ER22/23EK Polymorphism in the Glucocorticoid Receptor Gene with Survival and C-Reactive Protein Levels in Elderly Men, 158

The Further Evolution of Hyperparathryoidism: Implications for Clinical Care (E), 884

BULLAE AND SWEAT GLAND NECROSIS Pressure-induced Bullae and Sweat Gland Necrosis Following Chemotherapy Induction (LE), 441

988

Sex- and Age-Related Differences in the Prognostic Value of C-Reactive Protein in Patients with Angiographic Coronary Artery Disease, 657

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CALCIUM ANTAGONISTS Suboptimal Pharmacotherapeutic Management of Chronic Stable Angina in the Primary Care Setting, 234 CANCER Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 The Association between Quality Improvement Activities Performed by Managed Care Organizations and Quality of Care, 297 Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19 Garcin Syndrome Associated with Metastatic Colorectal Carcinoma (LE), 210

Subject Index

Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719 Reducing PSAnxiety: The Importance of Noninvasive Chronic Disease Management in Prostate Cancer Detection and Treatment (E), 796 Systematic Reviews of Herbal Medicines (LE), 533 Telomere Maintenance in Clinical Medicine (R), 262 CARBON MONOXIDE POISONING Transient Cardiac Dysfunction in Acute Carbon Monoxide Poisoning (LE), 623 CARDIAC ARREST Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 CARDIAC ARTERIES Routine Screening Angiography of Extracardiac Arteries During Cardiac Catheterization: Angiographer’s Delirium or Common Sense? (LE), 443 CARDIAC CATHETERIZATION Pulmonary Hypertension in Sickle Cell Disease, 665 Routine Screening Angiography of Extracardiac Arteries During Cardiac Catheterization: Angiographer’s Delirium or Common Sense? (LE), 443 CARDIAC DYSFUNCTION Transient Cardiac Dysfunction in Acute Carbon Monoxide Poisoning (LE), 623 CARDIAC EVENTS Does the Extent of Malperfusion or Ischemia on Stress Testing Predict Future Cardiac Events? (E), 58 CARDIAC SURGERY Magnesium Prophylaxis for Arrhythmias after Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials, 325 CARDIOMYOPATHY Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Presentation, Diagnosis, and Management, 685 Association of ␤-Adrenergic Receptor Polymorphisms and Progression to Heart

Failure in Patients with Idiopathic Dilated Cardiomyopathy, 451 Polymorphisms of ␤-adrenergic Receptors in Heart Failure (E), 525 Sex-Based Comparison of Survival in Referred Patients with Hypertrophic Cardiomyopathy (LE), 65 CARDIOPULMONARY ARREST Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 CARDIOVASCULAR DISEASE Antidepressants and Risk of First-Time Hospitalization for Myocardial Infarction: A Population-Based Case-control Study, 732 Anything Does Not Go: Defining and Refining Inverventions Designed to Improve Quality in Cardiovascular Diseases (E), 433 C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499 Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32 Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19 Does Disease Management Improve Clinical and Economic Outcomes in Patients with Chronic Diseases? A Systematic Review (R), 182 Effects of Statins on Vascular Structure and Function: A Systematic Review, 775 Insulin Resistance and the Endothelium (R), 109 Secular Trends in Cardiovascular Disease Mortality, Incidence, and Case Fatality Rates in Adults in the United States, 219 CARDIOVERTER-DEFIBRILLATORS Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Presentation, Diagnosis, and Management, 685 CATARACTS Hereditary Hyperferritinemia-Cataract Syndrome: A Novel Mutation in the IronResponsive Element of the L-Ferritin Gene in a French Family (LE), 138 December 15, 2004

CEREBRAL INFARCTION Correlation of Lymphocyte Heat Shock Protein 70 Levels with Neurologic Deficits in Elderly Patients with Cerebral Infarction, 406 CERTIFICATION The Future of Certification and Recertification (APM), 140 Modernizing the Paths to Certification in Internal Medicine and Its Subspecialties (E), 133 CHEMOTHERAPY Pressure-induced Bullae and Sweat Gland Necrosis Following Chemotherapy Induction (LE), 441 Telomere Maintenance in Clinical Medicine (R), 262 CHEST PAIN Prognostic Importance of Presenting Symptoms in Patients Undergoing Exercise Testing for Evaluation of Known or Suspected Coronary Disease, 380 CHEST RADIOGRAPHS Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 Value of Initial Chest Radiographs for Predicting Clinical Outcomes in Patients with Severe Acute Respiratory Syndrome, 249 CHOLESTEROL Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 CHRONIC ATROPHIC GASTRITIS Systematic Reviews of Herbal Medicines (LE), 533 CHRONIC DISEASE Does Disease Management Improve Clinical and Economic Outcomes in Patients with Chronic Diseases? A Systematic Review (R), 182 Reducing PSAnxiety: The Importance of Noninvasive Chronic Disease Management in Prostate Cancer Detection and Treatment (E), 796

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Subject Index

CHRONIC HEART FAILURE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 CHRONIC OBSTRUCTIVE PULMONARY DISEASE Beta-blockers as Single-Agent Therapy for Hypertension and the Risk of Mortality among Patients with Chronic Obstructive Pulmonary Disease, 925 Cost-effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (LE), 618 CHURG-STRAUSS SYNDROME The Antineutrophil Cytoplasmic Antibody-Associated Vasculitides (R), 39 CIRCADIAN VARIATION Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome, 469 Cardiac Autonomic Dysfunction in Gulf War Syndrome: Veterans Hearts Don’t Rest at Night (E), 531 CIRRHOSIS Reversibility of Cirrhosis in Autoimmune Hepatitis (BO), 125 CLENBUTEROL FOOD POISONING Proposed Guidelines for Clenbuterol Food Poisoning (LE), 362 CLERKSHIP DIRECTORS IN INTERNAL MEDICINE The Clerkship Directors in Internal Medicine’s Agenda for Advancing Medical Student Education in Internal Medicine (APM), 713 CLINICAL GUIDELINES Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 Clinician Awareness of Adherence to Hypertension Guidelines, 747 CLINICAL PERFORMANCE The Association between Quality Improvement Activities Performed by Man990

December 15, 2004

aged Care Organizations and Quality of Care, 297 From Motives to Results: Improving the Effectiveness of Quality Improvement (E), 359 CLINICAL PREDICTION RULES Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 CLINICIAN AWARENESS OF GUIDELINE ADHERENCE Clinician Awareness of Adherence to Hypertension Guidelines, 747 COGNITIVE FUNCTIONING Randomized Trial of the Effects of Simvastatin on Cognitive Functioning in Hypercholesterolemic Adults, 823 COGNITIVE IMPAIRMENT Falls and Mobility Limitations in Older People: Measures of Higher Cerebral Integration Are Also Important (LE), 971 COLONOSCOPY Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193 COLORECTAL CARCINOMA Garcin Syndrome Associated with Metastatic Colorectal Carcinoma (LE), 210 COMMERCIAL SUPPORT Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842 Commercial Support and Bias in Pharmaceutical Research (E), 876 COMMUNICATION Caring for Our Future Selves (APM), 537 COMMUNITY-ACQUIRED PNEUMONIA Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726

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COMMUNITY-LIVING ELDERLY The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484 COMPUTED TOMOGRAPHY Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193 COMPUTERIZED ALGORITHM Misdaignosis of Atrial Fibrillation and Its Clinical Consequences, 636 Overreliance on Computerized Algorithms to Interpret Electrocardiograms (E), 706 CONGENITAL ANALBUMINEMIA Treatment of Severe Hypercholesterolemia with Atorvastatin in Congenital Analbuminemia (LE), 803 CONTINUOUS POSITIVE AIRWAY PRESSURE Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 CONTRAST-RELATED NEPHROPATHY Has Acetylcysteine Use Changed the Incidence of Contrast Nephropathy in Hospitalized Patients? A Before-After Study (BO), 948 Is Acetylcysteine Effective in Preventing Contrast-Related Nephropathy? A Metaanalysis (R), 938 CONTROLLED TRIALS Magnesium Prophylaxis for Arrhythmias after Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials, 325 CORONARY DISEASE Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 Bedside Diagnosis of Coronary Artery Disease: A Systematic Review (R), 334

Subject Index

The Decline in Coronary Heart Disease: Determining the Paternity of Success (E), 274

CRYPTOSPORIDIUM PARVUM Cases from the Osler Medical Service at Johns Hopkins University (IO), 523

Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596

CYST A Hydatid Cyst Presenting as an Axillary Mass (LE), 363

Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 Macrophage Migration Inhibitory Factor and the Risk Myocardial Infarction or Death Due to Coronary Artery Disease in Adults without Prior Myocardial Infarction or Stroke: The EPIC-Norfold Prospective Population Study, 390 Prognostic Importance of Presenting Symptoms in Patients Undergoing Exercise Testing for Evaluation of Known or Suspected Coronary Disease, 380 Sex- and Age-Related Differences in the Prognostic Value of C-Reactive Protein in Patients with Angiographic Coronary Artery Disease, 657 Temporal Trends in the Incidence of Coronary Disease, 228 CORONARY STENTING Sex-Associated Differences in Clinical Outcomes after Coronary Stenting in Patients with Diabetes Mellitus, 830 CORONARY SYNDROMES ST Depression as a Long-term Risk Predictor in the Era of Invasive Management of Coronary Syndromes (E), 200 CORTICOSTEROIDS A 1-Week Course of Corticosteroids in the Treatment of Eosinophilic Meningitis (LE), 802 Cost-effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (LE), 618 COUNSELING Reducing PSAnxiety: The Importance of Noninvasive Chronic Disease Management in Prostate Cancer Detection and Treatment (E), 796

CYSTITIS Predictors of Urinary Tract Infection after Menopause: A Prospective Study, 903 D-DIMER Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 Why Not Test for Hypercoagulability in Patients with Idiopathic Venous Thromboembolism (LE), 801 DANAZOL Danazol, Idiopathic Thrombocytopenic Purpura, and Thrombopoietin (LE), 972 DEATH CERTIFICATES Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 DECISION-MAKER CHARACTERISTICS The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 DEEP VEIN THROMBOEMBOLISM Venous Thromboembolism in Pregnancy: 21-Year Trends (BO), 121 DEEP VEIN THROMBOSIS Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19 Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 DELIVERY OF CARE Caring for Our Future Selves (APM), 537 DEMENTIA WITH LEWY BODIES Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412 December 15, 2004

DENIAL Reimbursement Denial and Reversal by Health Plans at a University Hospital, 629 Utilization Management: A Bad Review (E), 703 DIABETES The Association between Quality Improvement Activities Performed by Managed Care Organizations and Quality of Care, 297 Insulin Resistance and the Endothelium (R), 109 Long-term Effectiveness of Lifestyle and Behavioral Weight Loss Interventions in Adults with Type 2 Diabetes: A Metaanalysis, 762 Pioglitazone-induced Heart Failure Despite Normal Left Ventricular Function (LE), 973 Predictors of Urinary Tract Infection after Menopause: A Prospective Study, 903 Requirement for Hypertension and Hyperlipidemia Medication in U.S. and Japanese Patients with Diabetes (LE), 711 Sex-Associated Differences in Clinical Outcomes after Coronary Stenting in Patients with Diabetes Mellitus, 830 Treatment of Diabetic Ketoacidosis: Should Mode of Insulin Administration Dictate Use of Intensive Care Facilities? (E), 357 DIARRHEA Cases from the Osler Medical Service at Johns Hopkins University (IO), 523 DICLOFENAC Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100 DIGOXIN Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 DILATED CARDIOMYOPATHY Association of ␤-Adrenergic Receptor Polymorphisms and Progression to Heart Failure in Patients with Idiopathic Dilated Cardiomyopathy, 451

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Subject Index

DISABILITY The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484 DISCHARGE INTERVIEW Effects of a Structured Patient-Centered Discharge Interview on Patients’ Knowledge about Their Medications, 563 DISEASE MANAGEMENT Does Disease Management Improve Clinical and Economic Outcomes in Patients with Chronic Diseases? A Systematic Review (R), 182 DNA REPAIR Genes, Rates of Aging, and Duration of Human Life (E), 882 The Genetics of Human Longevity (R), 851 DOBUTAMINE STRESS ECHOCARDIOGRAPHY Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 DOWNGRADE Reimbursement Denial and Reversal by Health Plans at a University Hospital, 629 Utilization Management: A Bad Review (E), 703 DRUG ABUSE Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607 DRUG STUDIES Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842 Commercial Support and Bias in Pharmaceutical Research (E), 876 DUCHENNE MUSCULAR DYSTROPHY A New Lease on Life for Patients with Duchenne Muscular Dystrophy in Japan (LE), 363 992

December 15, 2004

DUTY HOURS Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 A Case for the 80 Duty-hour Week, 879 DYSMETABOLIC SYNDROME The Glucocorticoid Receptor Gene, Longevity, and the Complex Disorders of Western Societies (E), 204 DYSPNEA Dyspnea in a Woman with a Permanent Pacemaker (LE), 535 ECHOCARDIOGRAPHY Does the Extent of Malperfusion or Ischemia on Stress Testing Predict Future Cardiac Events? (E), 58 Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 ECONOMIC OUTCOMES Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32 Does Disease Management Improve Clinical and Economic Outcomes in Patients with Chronic Diseases? A Systematic Review (R), 182 EDITORIAL TEAM Thanks and Best Wishes (E), 960 EDUCATION Advancing Academic Subspecialty Medicine: The Agenda for the Future of the Association of Subspecialty Professors (APM), 806 Association of Professors of Medicine: Unifying Internal Medicine to Improve Health Care (APM), 974 The Association of Program Directors in Internal Medicine: Promoting Excellence in Internal Medicine Graduate Medical Education (APM), 894 Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 The Case for Invigorating Internal Medicine (APM), 365 A Case for the 80 Duty-hour Week, 879

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The Clerkship Directors in Internal Medicine’s Agenda for Advancing Medical Student Education in Internal Medicine (APM), 713 Educational Disadvantage Impairs Functional Recovery after Hospitalization in Older Persons, 650 The Future of Certification and Recertification (APM), 140 The Future of Financing Medical Education: Questions About Medicare’s Role (APM), 287 The Future of Hospital Medicine: Evolution or Revolution? (APM), 446 Halfway Toward Healing a Broken System: Fellowship Recruitment in Internal Medicine (APM), 69 Internal Medicine Reformation, 107 Modernizing the Paths to Certification in Internal Medicine and Its Subspecialties (E), 133 Role of Administrators of Internal Medicine in Improving Departments of Internal Medicine (APM), 626 80-HOUR WORKWEEK Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 A Case for the 80 Duty-hour Week, 879 ELDERLY Association of the ER22/23EK Polymorphism in the Glucocorticoid Receptor Gene with Survival and C-Reactive Protein Levels in Elderly Men, 158 Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Caring for Our Future Selves (APM), 537 Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709 Correlation of Lymphocyte Heat Shock Protein 70 Levels with Neurologic Deficits in Elderly Patients with Cerebral Infarction, 406 The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484

Subject Index

Educational Disadvantage Impairs Functional Recovery after Hospitalization in Older Persons, 650 Insulin-Like Growth Factor 1 as a Predictor of Ischemic Stroke Outcome in the Elderly, 312 Falls and Mobility Limitations in Older People: Measures of Higher Cerebral Integration Are Also Important (LE), 971 Regional Variations in Racial Differences in the Treatment of Elderly Patients Hospitalized with Acute Myocardial Infarction, 811 ELECTROCARDIOGRAPHY Misdaignosis of Atrial Fibrillation and Its Clinical Consequences, 636 Overreliance on Computerized Algorithms to Interpret Electrocardiograms (E), 706 Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145 ST Depression as a Long-term Risk Predictor in the Era of Invasive Management of Coronary Syndromes (E), 200 EMERGENCY DEPARTMENT Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479 Uncomplicated Alcohol Intoxication in the Emergency Department: An Analysis of the National Hospital Ambulatory Medical Care Survey (BO), 863 ENCEPHALITIS Prognostic Importance of Lymphopenia in West Nile Encephalitis, 710 ENCEPHALOPATHY Wernicke Encephalopathy—An Emerging Trend After Bariatric Surgery (LE), 804 ENDOCARDITIS The Lack of Diagnostic Value of the Indium Scan in Acute Bacterial Endocarditis (LE), 621 ENDOTHELIUM DYSFUNCTION Insulin Resistance and the Endothelium (R), 109

EOSINOPHILIC MENINGITIS A 1-Week Course of Corticosteroids in the Treatment of Eosinophilic Meningitis (LE), 802 EPIDEMIOLOGY Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 ERYTHROPHAGOCYTOSIS Severe Intramedullary Erythrophagocytosis Following Red Blood Cell Transfusion (LE), 67 ESOPHAGOGASTRODUODENOSCOPY Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193 ESSENTIAL THROMBOCYTOPENIA Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 ETHNICITY Differences in Treatment Outcome for Hepatitis C among Ethnic Groups, 163 Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791 Race, Region, and the Quest for Quality in Cardiovascular Care (E), 874 Requirement for Hypertension and Hyperlipidemia Medication in U.S. and Japanese Patients with Diabetes (LE), 711 ETIDRONATE Comparative Efficacy of Hormone Replacement Therapy, Etidronate, Calcitonin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549 EVIDENCE-BASED THERAPY Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 December 15, 2004

EXERCISE CAPACITY Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 EXERCISE TESTING Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 Prognostic Importance of Presenting Symptoms in Patients Undergoing Exercise Testing for Evaluation of Known or Suspected Coronary Disease, 380 EXERCISE TOLERANCE Risk Factors for Nursing Home Placement following Major Nonemergent Surgery, 82 EXTRA CARDIAC ARTERIES Routine Screening Angiography of Extracardiac Arteries During Cardiac Catheterization: Angiographer’s Delirium or Common Sense? (LE), 443 EXTRAMEDULLARY TUBERCULOMA Spinal Cord Compression From Intradural Extramedullary Tuberculoma (LE), 620 FALL PREVENTION Broader Strategies for Hip Fracture Prevention (LE), 137 FALSE-POSITIVES Do Aspirin and Nonsteroidal Anti-inflammatory Drugs Cause False-positive Fecal Occult Blood Test Results? A Prospective Study in a Cohort of Veterans, 837 FANCONI SYNDROME Tenofovir-Associated Nephrotoxicity: Fanconi Syndrome and Renal Failure, 282 FATALITY Secular Trends in Cardiovascular Disease Mortality, Incidence, and Case Fatality Rates in Adults in the United States, 219

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Subject Index

FECAL OCCULT BLOOD TESTS Do Aspirin and Nonsteroidal Anti-inflammatory Drugs Cause False-positive Fecal Occult Blood Test Results? A Prospective Study in a Cohort of Veterans, 837 FEDERAL FUNDING The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213 FELLOWSHIP RECRUITMENT Halfway Toward Healing a Broken System: Fellowship Recruitment in Internal Medicine (APM), 69 FEMALE PRIMARY CARE PHYSICIANS Are Patients More Likely to See Physicians of the Same Sex? Recent National Trends in Primary Care Medicine, 575 The New Faces of Primary Care (E), 613 FEMORAL ARTERIAL EMBOLIZATION Cases from the Osler Medical Service at Johns Hopkins University (IO), 196 FERRITIN Hereditary Hyperferritinemia-Cataract Syndrome: A Novel Mutation in the IronResponsive Element of the L-Ferritin Gene in a French Family (LE), 138 FITNESS Fitness versus Physical Activity Patterns in Predicting Mortality in Men, 912 FLUOROQUINOLONE MONOTHERAPY Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726 FOAM CELL GENERATION C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499 FOOD POISONING Proposed Guidelines for Clenbuterol Food Poisoning (LE), 362 994

December 15, 2004

FORCED EXPIRATORY VOLUME IN 1 SECOND (FEV1) Forced Expiratory Volume in 1 Second and Physical Activity in the General Population (BO), 270

Commercial Support and Bias in Pharmaceutical Research (E), 876

FRACTURES Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919

The Future of Financing Medical Education: Questions About Medicare’s Role (APM), 287

Broader Strategies for Hip Fracture Prevention (LE), 137 Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966 Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952 Serum Vitamin A Concentration and the Risk of Hip Fracture among Women 50 to 74 Years Old in the United States: A Prospective Analysis of the NHANES I Follow-up Study, 169 FRAGILITY FRACTURES Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966 FRAILTY The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484 FUNCTIONAL RECOVERY Educational Disadvantage Impairs Functional Recovery after Hospitalization in Older Persons, 650 FUNCTIONAL STATUS Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 FUNDING Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842

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The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213

GABAPENTIN Gabapentin for Intractable Hiccup (LE), 279 GAIT APRAXIA Falls and Mobility Limitations in Older People: Measures of Higher Cerebral Integration Are Also Important (LE), 971 GARCIN SYNDROME Garcin Syndrome Associated with Metastatic Colorectal Carcinoma (LE), 210 GASTRIC BYPASS SURGERY Wernicke Encephalopathy—An Emerging Trend After Bariatric Surgery (LE), 804 GASTRITIS Low Plasma Ghrelin Levels in Patients with Helicobacter pylori Associated Gastritis (BO), 429 Systematic Reviews of Herbal Medicines (LE), 533 GASTROINTESTINAL BLEEDING Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 GASTROINTESTINAL COMPLICATIONS Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100 GENE THERAPY Telomere Maintenance in Clinical Medicine (R), 262 GENETICS Genes, Rates of Aging, and Duration of Human Life (E), 882

Subject Index

The Genetics of Human Longevity (R), 851 The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615

GULF WAR SYNDROME Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome, 469

Pioglitazone-induced Heart Failure Despite Normal Left Ventricular Function (LE), 973 Polymorphisms of ␤-adrenergic Receptors in Heart Failure (E), 525

GERIATRIC CARE Caring for Our Future Selves (APM), 537

Cardiac Autonomic Dysfunction in Gulf War Syndrome: Veterans Hearts Don’t Rest at Night (E), 531

Rheumatoid Arthritis and Heart Failure (LE), 709

GHRELIN Helicobacter pylori and Ghrelin: Interrelated Players in Body-weight Regulation? (E), 436

HARMS Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582

HEAT SHOCK PROTEIN 70 Correlation of Lymphocyte Heat Shock Protein 70 Levels with Neurologic Deficits in Elderly Patients with Cerebral Infarction, 406

Low Plasma Ghrelin Levels in Patients with Helicobacter pylori Associated Gastritis (BO), 429 GIANT CELL AORTITIS 25-Year Follow-up of a Case of Giant Cell Aortitis (LE), 625 GLIOBLASTOMA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 GLUCOCORTICOID RECEPTOR GENE Association of the ER22/23EK Polymorphism in the Glucocorticoid Receptor Gene with Survival and C-Reactive Protein Levels in Elderly Men, 158 The Glucocorticoid Receptor Gene, Longevity, and the Complex Disorders of Western Societies (E), 204 GLUCOSAMINE Effectiveness of Glucosamine for Symptoms of Knee Osteoarthritis: Results from an Internet-Based Randomized DoubleBlind Controlled Trial, 643 GRAFT OCCLUSION Benefits of Antithrombotic Therapy After Infrainguinal Bypass Grafting: A MetaAnalysis, 93 THE GREEN JOURNAL Thanks and Best Wishes (E), 960 GREEN TEA Systematic Reviews of Herbal Medicines (LE), 533 GUIDELINE ADHERENCE Clinician Awareness of Adherence to Hypertension Guidelines, 747

HCG TEST Hyperthyroidism and a Negative Urine hCG Test in Molar Pregnancy (LE), 889 HCV-RELATED CHRONIC HEPATITIS Thyroid Disorders in Chronic Hepatitis C, 10 HEADACHE A 1-Week Course of Corticosteroids in the Treatment of Eosinophilic Meningitis (LE), 802 HEART ATTACK Hypertension Control Rates: Time for Translation of Guidelines into Clinical Practice (E), 62 HEART FAILURE Anything Does Not Go: Defining and Refining Inverventions Designed to Improve Quality in Cardiovascular Diseases (E), 433 Association of ␤-Adrenergic Receptor Polymorphisms and Progression to Heart Failure in Patients with Idiopathic Dilated Cardiomyopathy, 451 Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 Effects of Treatment Recommendations and Specialist Intervention on Care Provided by Primary Care Physicians to Patients with Myocardial Infarction or Heart Failure, 371 December 15, 2004

HELICOBACTER PYLORI Low Plasma Ghrelin Levels in Patients with Helicobacter pylori Associated Gastritis (BO), 429 HEMOPTYSIS Pulmonary Artery Aneurysms in Behc¸et Syndrome (BO), 867 HEMORRHAGE Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 HEMORRHAGIC STROKE Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 HENOCH-SCHÖNLEIN PURPURA Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516 HEPARIN Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 HEPATIC ADVERSE EFFECTS Newer Disease-Modifying Antirheumatic Drugs and the Risk of Serious Hepatic Adverse Events in Patients with Rheumatoid Arthritis, 87 HEPATIC FIBROSIS Reversibility of Cirrhosis in Autoimmune Hepatitis (BO), 125

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Subject Index

HEPATITIS Reversibility of Cirrhosis in Autoimmune Hepatitis (BO), 125 HEPATITIS B Thyroid Disorders in Chronic Hepatitis C, 10 HEPATITIS C Differences in Treatment Outcome for Hepatitis C among Ethnic Groups, 163 Hepatitis C and Thyroid Autoimmunity: Is There a Link? (E), 60

HORMONE REPLACEMENT THERAPY Comparative Efficacy of Hormone Replacement Therapy, Etidronate, Calcitonin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549

The Genetics of Human Longevity (R), 851

HOSPITAL ADMISSION Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305

HYDATIDIFORM MOLE Hyperthyroidism and a Negative Urine hCG Test in Molar Pregnancy (LE), 889

Thyroid Disorders in Chronic Hepatitis C, 10

HOSPITAL TEACHING STATUS Effects of Weekend Admission and Hospital Teaching Status on In-hospital Mortality, 151

HERBAL MEDICINES Systematic Reviews of Herbal Medicines (LE), 533

HOSPITALISTS The Future of Hospital Medicine: Evolution or Revolution? (APM), 446

HICCUP Gabapentin for Intractable Hiccup (LE), 279

HOSPITALIZATION Antidepressants and Risk of First-Time Hospitalization for Myocardial Infarction: A Population-Based Case-control Study, 732

Hepatitis C Treatment Update, 344

HIP FRACTURE Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 Broader Strategies for Hip Fracture Prevention (LE), 137 Serum Vitamin A Concentration and the Risk of Hip Fracture among Women 50 to 74 Years Old in the United States: A Prospective Analysis of the NHANES I Follow-up Study, 169 HIV Hyperviscosity Syndrome in an HIV-1— Positive Patient (LE), 891 HOMOCYSTEINE Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 HORDALAND HOMOCYSTEINE STUDY Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 996

December 15, 2004

Educational Disadvantage Impairs Functional Recovery after Hospitalization in Older Persons, 650 Regional Variations in Racial Differences in the Treatment of Elderly Patients Hospitalized with Acute Myocardial Infarction, 811 The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 Self-Reported Management of Pain in Hospitalized Patients: Link Between Process and Outcome, 569 Waiting for Urgent Procedures on the Weekend among Emergently Hospitalized Patients, 175 HUMAN IMMUNODEFICIENCY VIRUS (HIV) Bacterial Pyomyositis in the United States (R), 420

HYDATID CYST A Hydatid Cyst Presenting as an Axillary Mass (LE), 363

HYPERALUMINEMIA Aluminum in Antiperspirants: More Than Just Skin Deep (E), 969 Hyperaluminemia in a Woman Using an Aluminum-containing Antiperspirant for 4 Years (BO), 956 HYPERCALCEMIA Hypercalcemia in Isolated Hypothalamic-Pituitary Langerhans Cell Histiocytosis with No Bone Lesions (LE), 533 HYPERCHOLESTEROLEMIA Randomized Trial of the Effects of Simvastatin on Cognitive Functioning in Hypercholesterolemic Adults, 823 Treatment of Severe Hypercholesterolemia with Atorvastatin in Congenital Analbuminemia (LE), 803 HYPERCOAGULABILITY Why Not Test for Hypercoagulability in Patients with Idiopathic Venous Thromboembolism (LE), 801 HYPERFERRITINEMIA Hereditary Hyperferritinemia-Cataract Syndrome: A Novel Mutation in the IronResponsive Element of the L-Ferritin Gene in a French Family (LE), 138 HYPERLIPIDEMIA Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596

Cases from the Osler Medical Service at Johns Hopkins University (IO), 523

Requirement for Hypertension and Hyperlipidemia Medication in U.S. and Japanese Patients with Diabetes (LE), 711

HUMAN LONGEVITY Genes, Rates of Aging, and Duration of Human Life (E), 882

HYPERPARATHYROIDISM Characterization of Normocalcemic Primary Hyperparathyroidism (BO), 861

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Subject Index

HYPERTENSION Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Beta-blockers as Single-Agent Therapy for Hypertension and the Risk of Mortality among Patients with Chronic Obstructive Pulmonary Disease, 925 Clinician Awareness of Adherence to Hypertension Guidelines, 747 Hypertension Control Rates: Time for Translation of Guidelines into Clinical Practice (E), 62 Identifying Gaps Between Guidelines and Clinical Practice in the Evaluation and Treatment of Patients with Hypertension, 14 Pulmonary Hypertension in Sickle Cell Disease, 665 Requirement for Hypertension and Hyperlipidemia Medication in U.S. and Japanese Patients with Diabetes (LE), 711 HYPERTHYROIDISM Hyperthyroidism and a Negative Urine hCG Test in Molar Pregnancy (LE), 889 HYPERTROPHIC CARDIOMYOPATHY Sex-Based Comparison of Survival in Referred Patients with Hypertrophic Cardiomyopathy (LE), 65 HYPERVISCOSITY SYNDROME Hyperviscosity Syndrome in an HIV-1— Positive Patient (LE), 891 HYPONATREMIA Prognostic Importance of Hyponatremia in Acute ST-Elevation Myocardial Infarction, 242 HYPOPARATHYROIDISM The Further Evolution of Hyperparathryoidism: Implications for Clinical Care (E), 884 HYPOTENSION Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607

HYPOTHALAMIC AMENORRHEA Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966 HYPOTHYROIDISM Disturbed Metabolism of Remnant Lipoproteins in Patients with Subclinical Hypothyroidism (BO), 696 Thyroid Disorders in Chronic Hepatitis C, 10 IDIOPATHIC THROMBOCYTOPENIC PURPURA Danazol, Idiopathic Thrombocytopenic Purpura, and Thrombopoietin (LE), 972 IDIOPATHIC VENOUS THROMBOEMBOLISM Why Not Test for Hypercoagulability in Patients with Idiopathic Venous Thromboembolism (LE), 801 ILLICIT DRUG USE Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607 IMMUNODULATIONS Hepatitis C Treatment Update, 344 IMMUNOTHERAPY Telomere Maintenance in Clinical Medicine (R), 262 INCOME The Net Transfer Organs across Race, Sex, Age, and Income, 670 INDIUM SCAN The Lack of Diagnostic Value of the Indium Scan in Acute Bacterial Endocarditis (LE), 621 INFECTION Synovial Fluid Leukocyte Count and Differential for the Diagnosis of Prosthetic Knee Infection, 556 INFLAMMATION Genes, Rates of Aging, and Duration of Human Life (E), 882 The Genetics of Human Longevity (R), 851 A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein SubDecember 15, 2004

fractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398 INFLIXIMAB Refractory Neurosarcoidosis: A Dramatic Response to Infliximab (LE), 277 INFRAINGUINAL BYPASS GRAFTING Benefits of Antithrombotic Therapy After Infrainguinal Bypass Grafting: A MetaAnalysis, 93 INHALED CORTICOSTEROIDS Cost-effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (LE), 618 INSULIN Efficacy of Subcutaneous Insulin Lispro versus Continuous Intravenous Regular Insulin for the Treatment of Patients with Diabetic Ketoacidosis, 291 Pioglitazone-induced Heart Failure Despite Normal Left Ventricular Function (LE), 973 Treatment of Diabetic Ketoacidosis: Should Mode of Insulin Administration Dictate Use of Intensive Care Facilities? (E), 357 INSULIN-LIKE GROWTH FACTOR 1 Insulin-Like Growth Factor 1 as a Predictor of Ischemic Stroke Outcome in the Elderly, 312 INSULIN RESISTANCE Insulin Resistance and the Endothelium (R), 109 Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952 INSULIN SIGNALING Genes, Rates of Aging, and Duration of Human Life (E), 882 The Genetics of Human Longevity (R), 851 INTENSIVE CARE FACILITIES Treatment of Diabetic Ketoacidosis: Should Mode of Insulin Administration Dictate Use of Intensive Care Facilities? (E), 357

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Subject Index

INTERFERON Differences in Treatment Outcome for Hepatitis C among Ethnic Groups, 163 Hepatitis C Treatment Update, 344 INTERFERON ␣ Pure Red Cell Aplasia Following Pegylated Interferon ␣ Treatment (LE), 619 INTERLEUKIN 1 RECEPTOR ANTAGONISTS Beneficial Response to Interleukin 1 Receptor Antagonist in Traps (LE), 208 INTERNAL MEDICINE The Case for Invigorating Internal Medicine (APM), 365 Internal Medicine Reformation, 107 Modernizing the Paths to Certification in Internal Medicine and Its Subspecialties (E), 133 INTERVENTIONS Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479 Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596 INTESTINAL CANCER Systematic Reviews of Herbal Medicines (LE), 533 INTOXICATION Uncomplicated Alcohol Intoxication in the Emergency Department: An Analysis of the National Hospital Ambulatory Medical Care Survey (BO), 863

IRON DEFICIENCY ANEMIA Abdominal Computed Tomography in the Evaluation of Patients with Asymptomatic Iron Deficiency Anemia: A Prospective Study (BO), 193

L-FERRITIN GENE Hereditary Hyperferritinemia-Cataract Syndrome: A Novel Mutation in the IronResponsive Element of the L-Ferritin Gene in a French Family (LE), 138

ISCHEMIA Does the Extent of Malperfusion or Ischemia on Stress Testing Predict Future Cardiac Events? (E), 58

L-THYROXINE REPLACEMENT Disturbed Metabolism of Remnant Lipoproteins in Patients with Subclinical Hypothyroidism (BO), 696

ISCHEMIC HEART DISEASE ST Depression as a Long-term Risk Predictor in the Era of Invasive Management of Coronary Syndromes (E), 200

LABOR Adult Phenylketonuria (R), 590

ISCHEMIC STROKE Insulin-Like Growth Factor 1 as a Predictor of Ischemic Stroke Outcome in the Elderly, 312 JAPAN Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 KAPOSI SARCOMA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 KERATIN Increased Keratin Content Detected by Proteomic Analysis of Exhaled Breath Condensate from Healthy Persons Who Smoke, 51 KETOACIDOSIS Efficacy of Subcutaneous Insulin Lispro versus Continuous Intravenous Regular Insulin for the Treatment of Patients with Diabetic Ketoacidosis, 291

INTRADURAL EXTRAMEDULLARY TUBERCULOMA Spinal Cord Compression From Intradural Extramedullary Tuberculoma (LE), 620

Treatment of Diabetic Ketoacidosis: Should Mode of Insulin Administration Dictate Use of Intensive Care Facilities? (E), 357

IRON Hereditary Hyperferritinemia-Cataract Syndrome: A Novel Mutation in the IronResponsive Element of the L-Ferritin Gene in a French Family (LE), 138

KNEE OSTEOARTHRITIS Effectiveness of Glucosamine for Symptoms of Knee Osteoarthritis: Results from an Internet-Based Randomized DoubleBlind Controlled Trial, 643

998

December 15, 2004

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Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615 LANGERHANS CELL HISTIOCYTOSIS Hypercalcemia in Isolated Hypothalamic-Pituitary Langerhans Cell Histiocytosis with No Bone Lesions (LE), 533 LEADERSHIP The Association of Program Directors in Internal Medicine: Promoting Excellence in Internal Medicine Graduate Medical Education (APM), 894 LEFLUNOMIDE Newer Disease-Modifying Antirheumatic Drugs and the Risk of Serious Hepatic Adverse Events in Patients with Rheumatoid Arthritis, 87 LEFT VENTRICULAR FUNCTION Pioglitazone-induced Heart Failure Despite Normal Left Ventricular Function (LE), 973 LENGTH OF STAY Utilization Management: A Bad Review (E), 703 Waiting for Urgent Procedures on the Weekend among Emergently Hospitalized Patients, 175 LEPTIN Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966 Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952

Subject Index

LEUKEMIA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 Cases from the Osler Medical Service at Johns Hopkins University (IO), 55 LEUKOCYTE COUNT Synovial Fluid Leukocyte Count and Differential for the Diagnosis of Prosthetic Knee Infection, 556 LEUKOCYTOSIS Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607 LIFE EXPECTANCY The Decline in Coronary Heart Disease: Determining the Paternity of Success (E), 274 Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 LIFESTYLE The Case for Invigorating Internal Medicine (APM), 365 LIFESTYLE INTERVENTIONS Long-term Effectiveness of Lifestyle and Behavioral Weight Loss Interventions in Adults with Type 2 Diabetes: A Metaanalysis, 762 LIPID-LOWERING INTERVENTIONS Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596 LIPOPROTEIN SUBFRACTIONS A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein Subfractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398 LIPOPROTEINS Disturbed Metabolism of Remnant Lipoproteins in Patients with Subclinical Hypothyroidism (BO), 696 A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein Sub-

LISPRO Efficacy of Subcutaneous Insulin Lispro versus Continuous Intravenous Regular Insulin for the Treatment of Patients with Diabetic Ketoacidosis, 291

MACROPHAGE MIGRATION INHIBITORY FACTOR Macrophage Migration Inhibitory Factor and the Risk Myocardial Infarction or Death Due to Coronary Artery Disease in Adults without Prior Myocardial Infarction or Stroke: The EPIC-Norfold Prospective Population Study, 390

LIVER ABSCESS Low Sensitivity of Ultrasonography for the Early Diagnosis of Amebic Liver Abscess (BO), 519

MACROPHAGE RECRUITMENT C-Reactive Protein: From Innocent Bystander to Pivotal Mediator of Atherosclerosis (R), 499

LIVER DISEASE Reversibility of Cirrhosis in Autoimmune Hepatitis (BO), 125

MAGNESIUM PROPHYLAXIS Magnesium Prophylaxis for Arrhythmias after Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials, 325

fractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398

LONGEVITY Genes, Rates of Aging, and Duration of Human Life (E), 882 The Genetics of Human Longevity (R), 851 The Glucocorticoid Receptor Gene, Longevity, and the Complex Disorders of Western Societies (E), 204 LOW-CARBOHYDRATE DIET A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein Subfractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398 LUNG DISEASE Forced Expiratory Volume in 1 Second and Physical Activity in the General Population (BO), 270 LUPUS NEPHRITIS Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791 LYMPHOPENIA Prognostic Importance of Lymphopenia in West Nile Encephalitis, 710 MACROLIDE MONOTHERAPY Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726 December 15, 2004

MALPERFUSION Does the Extent of Malperfusion or Ischemia on Stress Testing Predict Future Cardiac Events? (E), 58 MANAGED CARE The Association between Quality Improvement Activities Performed by Managed Care Organizations and Quality of Care, 297 Managed Care Patient Protection or Provider Protection? A Qualitative Assessment, 932 From Motives to Results: Improving the Effectiveness of Quality Improvement (E), 359 MANAGEMENT SYSTEMS Role of Administrators of Internal Medicine in Improving Departments of Internal Medicine (APM), 626 MATERNAL PHENYLKETONURIA Adult Phenylketonuria (R), 590 The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615 MEDICAL PROFESSIONAL SOCIETY Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842 Commercial Support and Bias in Pharmaceutical Research (E), 876

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Subject Index

MEDICATION COMPLIANCE Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73

METABOLIC DISTURBANCES Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118

Clinician Awareness of Adherence to Hypertension Guidelines, 747

METABOLISM Disturbed Metabolism of Remnant Lipoproteins in Patients with Subclinical Hypothyroidism (BO), 696

Effects of a Structured Patient-Centered Discharge Interview on Patients’ Knowledge about Their Medications, 563 Patient Adherence: The Next Frontier in Quality Improvement (E), 130 MEDICATION-INDUCED PARKINSONISM Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412 MEDICATIONS Self-Reported Management of Pain in Hospitalized Patients: Link Between Process and Outcome, 569 MEDITERRANEAN FEVER Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516 MELOXICAM Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100 MEMBERSHIP The Clerkship Directors in Internal Medicine’s Agenda for Advancing Medical Student Education in Internal Medicine (APM), 713

METHOTREXATE Newer Disease-Modifying Antirheumatic Drugs and the Risk of Serious Hepatic Adverse Events in Patients with Rheumatoid Arthritis, 87 METHYLENETETRAHYDROFOLATE REDUCTASE Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 MICROBIOLOGY Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 MICROSCOPIC POLYANGITIS The Antineutrophil Cytoplasmic Antibody-Associated Vasculitides (R), 39 MISDIAGNOSIS Misdaignosis of Atrial Fibrillation and Its Clinical Consequences, 636 Overreliance on Computerized Algorithms to Interpret Electrocardiograms (E), 706

MEN Fitness versus Physical Activity Patterns in Predicting Mortality in Men, 912

MOLAR PREGNANCY Hyperthyroidism and a Negative Urine hCG Test in Molar Pregnancy (LE), 889

MENINGITIS A 1-Week Course of Corticosteroids in the Treatment of Eosinophilic Meningitis (LE), 802

MORTALITY Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963

Prognostic Importance of Lymphopenia in West Nile Encephalitis, 710

Beta-blockers as Single-Agent Therapy for Hypertension and the Risk of Mortality among Patients with Chronic Obstructive Pulmonary Disease, 925

MENOPAUSE Predictors of Urinary Tract Infection after Menopause: A Prospective Study, 903

Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799

1000

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Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 The Decline in Coronary Heart Disease: Determining the Paternity of Success (E), 274 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726 Effects of Weekend Admission and Hospital Teaching Status on In-hospital Mortality, 151 Fitness versus Physical Activity Patterns in Predicting Mortality in Men, 912 Prognostic Importance of Presenting Symptoms in Patients Undergoing Exercise Testing for Evaluation of Known or Suspected Coronary Disease, 380 Secular Trends in Cardiovascular Disease Mortality, Incidence, and Case Fatality Rates in Adults in the United States, 219 Sex-Based Comparison of Survival in Referred Patients with Hypertrophic Cardiomyopathy (LE), 65 Should U.S. Hospitals Go 24/7? (E), 202 MULTIPLE MYELOMA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 Severe Osteomyelitis of the Jaw in Longterm Survivors of Multiple Myeloma: A New Clinical Entity (LE), 440 MULTIPLE SYSTEM ATROPHY Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412 MUSCULAR DYSTROPHY A New Lease on Life for Patients with Duchenne Muscular Dystrophy in Japan (LE), 363 MYCOSIS FUNGOIDES WITH CIRCULATING SEZARY CELLS Cases from the Osler Medical Service at Johns Hopkins University (IO), 700 MYCOTIC AORTIC ANEURYSMS Cases from the Osler Medical Service at Johns Hopkins University (IO), 196

Subject Index

Mycotic Aneurysms of the Abdominal Aorta (LE), 208

Adults without Prior Myocardial Infarction or Stroke: The EPIC-Norfold Prospective Population Study, 390

MYELOFIBROSIS Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508

Prognostic Importance of Hyponatremia in Acute ST-Elevation Myocardial Infarction, 242

MYELOMA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508

Prognostic Value of Quantitative Troponin T Measurements in Unstable Angina/ Non-ST-Segment Elevation Acute Myocardial Infarction Treated Early and Predominantly with Percutaneous Coronary Intervention, 897

Severe Osteomyelitis of the Jaw in Longterm Survivors of Multiple Myeloma: A New Clinical Entity (LE), 440 MYELOPLASTIC SYNDROMES Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 MYOCARDIAL FIBROSIS Sex-Based Comparison of Survival in Referred Patients with Hypertrophic Cardiomyopathy (LE), 65 MYOCARDIAL INFARCTION Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73 Antidepressants and Risk of First-Time Hospitalization for Myocardial Infarction: A Population-Based Case-control Study, 732 Anything Does Not Go: Defining and Refining Inverventions Designed to Improve Quality in Cardiovascular Diseases (E), 433 Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963 Bedside Diagnosis of Coronary Artery Disease: A Systematic Review (R), 334 The Decline in Coronary Heart Disease: Determining the Paternity of Success (E), 274 Effects of Treatment Recommendations and Specialist Intervention on Care Provided by Primary Care Physicians to Patients with Myocardial Infarction or Heart Failure, 371 Macrophage Migration Inhibitory Factor and the Risk Myocardial Infarction or Death Due to Coronary Artery Disease in

Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145 Race, Region, and the Quest for Quality in Cardiovascular Care (E), 874

Heart Failure: A Randomized Controlled Trial, 541 NECROTIZING VASCULITIS Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516 NEOPLASTIC DISEASE Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 NEPHRITIS Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791 NEPHROPATHY Has Acetylcysteine Use Changed the Incidence of Contrast Nephropathy in Hospitalized Patients? A Before-After Study (BO), 948

Regional Variations in Racial Differences in the Treatment of Elderly Patients Hospitalized with Acute Myocardial Infarction, 811

Is Acetylcysteine Effective in Preventing Contrast-Related Nephropathy? A Metaanalysis (R), 938

Temporal Trends in the Incidence of Coronary Disease, 228

NEPHROTOXICITY Tenofovir-Associated Nephrotoxicity: Fanconi Syndrome and Renal Failure, 282

MYOCARDIAL INJURY Transient Cardiac Dysfunction in Acute Carbon Monoxide Poisoning (LE), 623 MYOCARDIAL PERFUSION SCANNING Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 NAPROXEN Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100 NATIONAL INSTITUTES OF HEALTH The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213

NEUROLOGIC DEFICITS Correlation of Lymphocyte Heat Shock Protein 70 Levels with Neurologic Deficits in Elderly Patients with Cerebral Infarction, 406 NEUROLOGIC DISEASE Falls and Mobility Limitations in Older People: Measures of Higher Cerebral Integration Are Also Important (LE), 971 NEUROPATHY Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516 NEUROSARCOIDOSIS Refractory Neurosarcoidosis: A Dramatic Response to Infliximab (LE), 277

NATRIURETIC PEPTIDE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611

NEWBORN SCREENING Adult Phenylketonuria (R), 590

Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic

The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615

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Subject Index

NHANES STUDY Hypertension Control Rates: Time for Translation of Guidelines into Clinical Practice (E), 62

NORMOCALCEMIC PRIMARY HYPERPARATHYROIDISM Characterization of Normocalcemic Primary Hyperparathyroidism (BO), 861

Serum Vitamin A Concentration and the Risk of Hip Fracture among Women 50 to 74 Years Old in the United States: A Prospective Analysis of the NHANES I Follow-up Study, 169

The Further Evolution of Hyperparathryoidism: Implications for Clinical Care (E), 884

NILE ENCEPHALITIS Prognostic Importance of Lymphopenia in West Nile Encephalitis, 710 NITRATES Suboptimal Pharmacotherapeutic Management of Chronic Stable Angina in the Primary Care Setting, 234 NONDIABETIC RENAL DISEASE Spironolactone and Angiotensin Receptor Blocker in Nondiabetic Renal Diseases (LE), 444 NONEMERGENT SURGERY Risk Factors for Nursing Home Placement following Major Nonemergent Surgery, 82 NONSTEROIDAL ANTI-INFLAMMATORY DRUGS Do Aspirin and Nonsteroidal Anti-inflammatory Drugs Cause False-positive Fecal Occult Blood Test Results? A Prospective Study in a Cohort of Veterans, 837 Effectiveness of Glucosamine for Symptoms of Knee Osteoarthritis: Results from an Internet-Based Randomized DoubleBlind Controlled Trial, 643 NONTRAUMATIC FRACTURE Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952 NOREPINEPHRINE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 1002

December 15, 2004

NURSING HOME PLACEMENT Risk Factors for Nursing Home Placement following Major Nonemergent Surgery, 82 OBESITY Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738 Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 Long-term Effectiveness of Lifestyle and Behavioral Weight Loss Interventions in Adults with Type 2 Diabetes: A Metaanalysis, 762 A Randomized Study Comparing the Effects of a Low-Carbohydrate Diet and a Conventional Diet on Lipoprotein Subfractions and C-Reactive Protein Levels in Patients with Severe Obesity, 398 Wernicke Encephalopathy—An Emerging Trend After Bariatric Surgery (LE), 804 OBSTRUCTIVE SLEEP APNEA Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 OREXIGENIC HORMONES Helicobacter pylori and Ghrelin: Interrelated Players in Body-weight Regulation? (E), 436

OSTEOPOROSIS Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 Broader Strategies for Hip Fracture Prevention (LE), 137 Comparative Efficacy of Hormone Replacement Therapy, Etidronate, Calcitonin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549 OUTCOMES Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738 Does Disease Management Improve Clinical and Economic Outcomes in Patients with Chronic Diseases? A Systematic Review (R), 182 Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 Sex-Associated Differences in Clinical Outcomes after Coronary Stenting in Patients with Diabetes Mellitus, 830 Value of Initial Chest Radiographs for Predicting Clinical Outcomes in Patients with Severe Acute Respiratory Syndrome, 249 PACEMAKER Dyspnea in a Woman with a Permanent Pacemaker (LE), 535 PAIN MANAGEMENT Self-Reported Management of Pain in Hospitalized Patients: Link Between Process and Outcome, 569

OSTEOARTHRITIS Effectiveness of Glucosamine for Symptoms of Knee Osteoarthritis: Results from an Internet-Based Randomized DoubleBlind Controlled Trial, 643

PARKINSON DISEASE Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412

OSTEOMYELITIS Severe Osteomyelitis of the Jaw in Longterm Survivors of Multiple Myeloma: A New Clinical Entity (LE), 440

PARKINSONIAN SYNDROMES Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412

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Subject Index

PATIENT ADHERENCE Patient Adherence: The Next Frontier in Quality Improvement (E), 130 PATIENT CHARACTERISTICS The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 PATIENT EDUCATION Effects of a Structured Patient-Centered Discharge Interview on Patients’ Knowledge about Their Medications, 563 PATIENT PREFERENCES Are Patients More Likely to See Physicians of the Same Sex? Recent National Trends in Primary Care Medicine, 575 The New Faces of Primary Care (E), 613 PATIENT PROTECTION Managed Care Patient Protection or Provider Protection? A Qualitative Assessment, 932 PEPTIDES Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 PERCUTANEOUS CORONARY INTERVENTION Prognostic Value of Quantitative Troponin T Measurements in Unstable Angina/ Non-ST-Segment Elevation Acute Myocardial Infarction Treated Early and Predominantly with Percutaneous Coronary Intervention, 897 PERCUTANOUS CORONARY INTERVENTION Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963

Commercial Support and Bias in Pharmaceutical Research (E), 876

PLASMA NOREPINEPHRINE Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611

PHENYLKETONURIA Adult Phenylketonuria (R), 590

Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541

The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615 PHYSICAL ACTIVITY Fitness versus Physical Activity Patterns in Predicting Mortality in Men, 912 Forced Expiratory Volume in 1 Second and Physical Activity in the General Population (BO), 270 PHYSICAL FRAILTY The Development of Insidious Disability in Activities of Daily Living among Community-Living Older Persons, 484 PHYSICIAN RECOMMENDATIONS The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 PHYSICIAN SEX Are Patients More Likely to See Physicians of the Same Sex? Recent National Trends in Primary Care Medicine, 575 The New Faces of Primary Care (E), 613 PIOGLITAZONE-INDUCED HEART FAILURE Pioglitazone-Induced Heart Failure Despite Normal Left Ventricular Function (LE), 973 PIROXICAM Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100

PERIPHERAL NEUROPATHY Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516

PLACENTAL ABRUPTION Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26

PHARMACEUTICAL RESEARCH Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842

PLASMA GHRELIN LEVELS Low Plasma Ghrelin Levels in Patients with Helicobacter pylori Associated Gastritis (BO), 429 December 15, 2004

PLATYPNEA-ORTHODEOXIA SYNDROME Platypnea-Orthodeoxia Syndrome Occurring After a Blunt Chest Trauma with Acute Tricuspid Regurgitation (LE), 890 PLEURAL EFFUSION Unilateral Transudative Pleural Effusion: An Exceptional Cause (LE), 888 PNEUMONIA Cases from the Osler Medical Service at Johns Hopkins University (IO), 353 Community-acquired Pneumonia Guidelines: Peering Back through the Looking Glass . . . Clearly? (E), 799 Effects of Guideline-Concordant Antimicrobial Therapy on Mortality among Patients with Community-Acquired Pneumonia, 726 Hyperviscosity Syndrome in an HIV-1— Positive Patient (LE), 891 Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 Solitary Nodular Form of Bronchiolitis Obliterans Organizing Pneumonia (LE), 887 POLYARTERITIS NODOSA Necrotizing Vasculitis Associated with Familial Mediterranean Fever (BO), 516 POLYCYTHEMIA VERA Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 POLYMORPHISMS Association of ␤-Adrenergic Receptor Polymorphisms and Progression to Heart Failure in Patients with Idiopathic Dilated Cardiomyopathy, 451

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Subject Index

Association of the ER22/23EK Polymorphism in the Glucocorticoid Receptor Gene with Survival and C-Reactive Protein Levels in Elderly Men, 158 Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 The Glucocorticoid Receptor Gene, Longevity, and the Complex Disorders of Western Societies (E), 204 Polymorphisms of ␤-adrenergic Receptors in Heart Failure (E), 525 POLYPS Systematic Reviews of Herbal Medicines (LE), 533 PRACTICE GUIDELINES Adherence with Osteoporosis Practice Guidelines: A Multilevel Analysis of Patient, Physician, and Practice Setting Characteristics, 919 PREDICTION RULES Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 PREGNANCY Associations between Maternal Methylenetetrahydrofolate Reductase Polymorphisms and Adverse Outcomes in Pregnancy: The Hordaland Homocysteine Study, 26 Venous Thromboembolism in Pregnancy: 21-Year Trends (BO), 121 PREVENTION Broader Strategies for Hip Fracture Prevention (LE), 137 PREVENTIVE HEALTH CARE Are Patients More Likely to See Physicians of the Same Sex? Recent National Trends in Primary Care Medicine, 575 The New Faces of Primary Care (E), 613 PRIMARY CARE Internal Medicine Reformation, 107 The New Faces of Primary Care (E), 613 Suboptimal Pharmacotherapeutic Management of Chronic Stable Angina in the Primary Care Setting, 234 1004

December 15, 2004

PRIMARY CARE ACCESS Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479

PROGRESSIVE SUPRANUCLEAR PALSY Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412

PRIMARY CARE PHYSICIANS Effects of Treatment Recommendations and Specialist Intervention on Care Provided by Primary Care Physicians to Patients with Myocardial Infarction or Heart Failure, 371

PROSTATE CANCER Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508

PRIMARY CARE TRENDS Are Patients More Likely to See Physicians of the Same Sex? Recent National Trends in Primary Care Medicine, 575

Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719 Reducing PSAnxiety: The Importance of Noninvasive Chronic Disease Management in Prostate Cancer Detection and Treatment (E), 796

The New Faces of Primary Care (E), 613 PRIMARY PULMONARY SPOROTRICHOSIS Cases from the Osler Medical Service at Johns Hopkins University (IO), 353 PROCESS OF CARE Effects of Increased Primary Care Access on Process of Care and Health Outcomes among Patients with Asthma Who Frequent Emergency Departments, 479 PROFESSIONAL COMPETENCIES Advancing Academic Subspecialty Medicine: The Agenda for the Future of the Association of Subspecialty Professors (APM), 806 PROFESSIONAL DEVELOPMENT The Future of Certification and Recertification (APM), 140 PROFESSIONALISM Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 PROGNOSTIC FACTORS Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 PROGRAM DIRECTORS The Association of Program Directors in Internal Medicine: Promoting Excellence in Internal Medicine Graduate Medical Education (APM), 894

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PROSTHETIC KNEE INFECTION Synovial Fluid Leukocyte Count and Differential for the Diagnosis of Prosthetic Knee Infection, 556 PROTEIN Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709 PROTEOMIC ANALYSIS Increased Keratin Content Detected by Proteomic Analysis of Exhaled Breath Condensate from Healthy Persons Who Smoke, 51 PROVIDER INTERESTS Managed Care Patient Protection or Provider Protection? A Qualitative Assessment, 932 PSYCHOLOGICAL EFFECTS Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719 PULMONARY ARTERY ANEURYSMS Pulmonary Artery Aneurysms in Behc¸et Syndrome (BO), 867 PULMONARY DISEASE Beta-blockers as Single-Agent Therapy for Hypertension and the Risk of Mortality among Patients with Chronic Obstructive Pulmonary Disease, 925 Cost-effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (LE), 618

Subject Index

From Motives to Results: Improving the Effectiveness of Quality Improvement (E), 359

RANDOMIZED CONTROLLED TRIALS Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582

Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677

QUALITY OF LIFE Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738

Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596

Venous Thromboembolism in Pregnancy: 21-Year Trends (BO), 121

Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611

PULMONARY HYPERTENSION Pulmonary Hypertension in Sickle Cell Disease, 665

Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541

PULMONARY EMBOLISM Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19

PULMONARY NODULE Solitary Nodular Form of Bronchiolitis Obliterans Organizing Pneumonia (LE), 887

RACE The Net Transfer Organs across Race, Sex, Age, and Income, 670

PULSE PRESSURE Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709

RACIAL DIFFERENCES Differences in Treatment Outcome for Hepatitis C among Ethnic Groups, 163

PURE RED CELL APLASIA Pure Red Cell Aplasia Following Pegylated Interferon ␣ Treatment (LE), 619

Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791

PYOMYOSITIS Bacterial Pyomyositis in the United States (R), 420 QUALITY IMPROVEMENT Anything Does Not Go: Defining and Refining Inverventions Designed to Improve Quality in Cardiovascular Diseases (E), 433 The Association between Quality Improvement Activities Performed by Managed Care Organizations and Quality of Care, 297 The Future of Certification and Recertification (APM), 140 From Motives to Results: Improving the Effectiveness of Quality Improvement (E), 359 Patient Adherence: The Next Frontier in Quality Improvement (E), 130 QUALITY OF CARE The Association between Quality Improvement Activities Performed by Managed Care Organizations and Quality of Care, 297

Race, Region, and the Quest for Quality in Cardiovascular Care (E), 874 Regional Variations in Racial Differences in the Treatment of Elderly Patients Hospitalized with Acute Myocardial Infarction, 811 Requirement for Hypertension and Hyperlipidemia Medication in U.S. and Japanese Patients with Diabetes (LE), 711 RADIOGRAPHY Has Acetylcysteine Use Changed the Incidence of Contrast Nephropathy in Hospitalized Patients? A Before-After Study (BO), 948 Is Acetylcysteine Effective in Preventing Contrast-Related Nephropathy? A Metaanalysis (R), 938 Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 Value of Initial Chest Radiographs for Predicting Clinical Outcomes in Patients with Severe Acute Respiratory Syndrome, 249 December 15, 2004

RED BLOOD CELL TRANSFUSION Severe Intramedullary Erythrophagocytosis Following Red Blood Cell Transfusion (LE), 67 REGIONAL VARIATIONS Regional Variations in Racial Differences in the Treatment of Elderly Patients Hospitalized with Acute Myocardial Infarction, 811 REIMBURSEMENT DENIAL Reimbursement Denial and Reversal by Health Plans at a University Hospital, 629 Utilization Management: A Bad Review (E), 703 REIMBURSEMENT DOWNGRADE Reimbursement Denial and Reversal by Health Plans at a University Hospital, 629 REIMBURSEMENT REVERSAL Reimbursement Denial and Reversal by Health Plans at a University Hospital, 629 Utilization Management: A Bad Review (E), 703 RENAL CELL CANCER Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 RENAL DISEASE Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791 Spironolactone and Angiotensin Receptor Blocker in Nondiabetic Renal Diseases (LE), 444 RENAL FAILURE Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607 Tenofovir-Associated Nephrotoxicity: Fanconi Syndrome and Renal Failure, 282

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Subject Index

RENAL GIANT CELL AORTITIS 25-Year Follow-up of a Case of Giant Cell Aortitis (LE), 625 RESEARCH Association of Funding and Findings of Pharmaceutical Research at a Meeting of a Medical Professional Society, 842 Commercial Support and Bias in Pharmaceutical Research (E), 876 The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213 The Future of Hospital Medicine: Evolution or Revolution? (APM), 446 RESIDENCY Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 Internal Medicine Reformation, 107 RESPIRATORY TRACT INFECTION Patients Admitted to Hospital with Suspected Pneumonia and Normal Chest Radiographs: Epidemiology, Microbiology, and Outcomes, 305 REVASCULARIZATION Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145

RIGHT VENTRICULAR CARDIOMYOPATHY Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Presentation, Diagnosis, and Management, 685 SCHOLARSHIP The Clerkship Directors in Internal Medicine’s Agenda for Advancing Medical Student Education in Internal Medicine (APM), 713 SCREENING Psychological Effects of a Suspicious Prostate Cancer Screening Test Followed by a Benign Biopsy Result, 719 SECONDARY SYPHILIS Cases from the Osler Medical Service at Johns Hopkins University (IO), 871 SECONDHAND SMOKE Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32 SECULAR TRENDS Secular Trends in Cardiovascular Disease Mortality, Incidence, and Case Fatality Rates in Adults in the United States, 219 SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRI) Antidepressants and Risk of First-Time Hospitalization for Myocardial Infarction: A Population-Based Case-control Study, 732

RHABDOMYOLYSIS Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607

SERUM CREATININE KINASE LEVELS Risk Factors for Renal Failure among 72 Consecutive Patients with Rhabdomyolysis Related to Illicit Drug Use (BO), 607

RHEUMATOID ARTHRITIS Newer Disease-Modifying Antirheumatic Drugs and the Risk of Serious Hepatic Adverse Events in Patients with Rheumatoid Arthritis, 87

SERUM LEPTIN Leptin and Fragility Fracture: Evidence for a Protective Effect in Humans (E), 966

Rheumatoid Arthritis and Heart Failure (LE), 709 RIBAVIRIN Differences in Treatment Outcome for Hepatitis C among Ethnic Groups, 163 Hepatitis C Treatment Update, 344 1006

December 15, 2004

Serum Leptin Level and the Risk of Nontraumatic Fracture (BO), 952 SERVICE AVAILABILITY Should U.S. Hospitals Go 24/7? (E), 202 SEVEN-DAY OPERATION Should U.S. Hospitals Go 24/7? (E), 202

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SEVERE ACUTE RESPIRATORY SYNDROME Value of Initial Chest Radiographs for Predicting Clinical Outcomes in Patients with Severe Acute Respiratory Syndrome, 249 SEX-RELATED DIFFERENCES The Net Transfer Organs across Race, Sex, Age, and Income, 670 Sex- and Age-Related Differences in the Prognostic Value of C-Reactive Protein in Patients with Angiographic Coronary Artery Disease, 657 Sex-Associated Differences in Clinical Outcomes after Coronary Stenting in Patients with Diabetes Mellitus, 830 SICKLE CELL DISEASE Pulmonary Hypertension in Sickle Cell Disease, 665 SIMVASTATIN Randomized Trial of the Effects of Simvastatin on Cognitive Functioning in Hypercholesterolemic Adults, 823 SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT) Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1 SINUS NODE FUNCTION Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome, 469 Cardiac Autonomic Dysfunction in Gulf War Syndrome: Veterans Hearts Don’t Rest at Night (E), 531 SLEEP APNEA Effects of Obesity on C-Reactive Protein Level and Metabolic Disturbances in Male Patients with Obstructive Sleep Apnea (BO), 118 SMOKE-FREE WORKPLACES Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32

Subject Index

SMOKING Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32 Forced Expiratory Volume in 1 Second and Physical Activity in the General Population (BO), 270 Increased Keratin Content Detected by Proteomic Analysis of Exhaled Breath Condensate from Healthy Persons Who Smoke, 51 SOBERING CENTER Uncomplicated Alcohol Intoxication in the Emergency Department: An Analysis of the National Hospital Ambulatory Medical Care Survey (BO), 863 SOCIOECONOMICS The Net Transfer Organs across Race, Sex, Age, and Income, 670 SODIUM Confounding Factors Affecting Association of Antihypertensive Medications and Pulse Pressure, 709 SOLITARY PULMONARY NODULE Solitary Nodular Form of Bronchiolitis Obliterans Organizing Pneumonia (LE), 887 SPECIALTIES The Case for Invigorating Internal Medicine (APM), 365 SPINAL CORD COMPRESSION Spinal Cord Compression From Intradural Extramedullary Tuberculoma (LE), 620 SPIRONOLACTONE Spironolactone and Angiotensin Receptor Blocker in Nondiabetic Renal Diseases (LE), 444 SPONDYLODISCITIS Spontaneous Spondylodiscitis Caused by Bacteroides Uniformis, 284

ST-ELEVATION MYOCARDIAL INFARCTION Prognostic Importance of Hyponatremia in Acute ST-Elevation Myocardial Infarction, 242 ST-SEGMENT DEPRESSION Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145

Assessing the Risk/Benefit Profile Before Recommending Aspirin for the Primary Prevention of Cardiovascular Events (E), 528 Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596 Insulin-Like Growth Factor 1 as a Predictor of Ischemic Stroke Outcome in the Elderly, 312

STANDARDS The Clerkship Directors in Internal Medicine’s Agenda for Advancing Medical Student Education in Internal Medicine (APM), 713

Macrophage Migration Inhibitory Factor and the Risk Myocardial Infarction or Death Due to Coronary Artery Disease in Adults without Prior Myocardial Infarction or Stroke: The EPIC-Norfold Prospective Population Study, 390

STATINS Adherence to Evidence-Based Therapies after Discharge for Acute Coronary Syndromes: An Ongoing Prospective, Observational Study, 73

STRUCTURED DISCHARGE INTERVIEW Effects of a Structured Patient-Centered Discharge Interview on Patients’ Knowledge about Their Medications, 563

Effects of Statins on Stroke Prevention in Patients with and without Coronary Heart Disease: A Meta-analysis of Randomized Controlled Trials, 596

SUBERYTHEMAL ULTRAVIOLET EXPOSURE Suberythemal Ultraviolet Exposure and Reduction in Blood Pressure (LE), 281

Effects of Statins on Vascular Structure and Function: A Systematic Review, 775 Patient Adherence: The Next Frontier in Quality Improvement (E), 130 Randomized Trial of the Effects of Simvastatin on Cognitive Functioning in Hypercholesterolemic Adults, 823 STENTING Sex-Associated Differences in Clinical Outcomes after Coronary Stenting in Patients with Diabetes Mellitus, 830 STOMACH CANCER Systematic Reviews of Herbal Medicines (LE), 533

SPOROTRICHOSIS Cases from the Osler Medical Service at Johns Hopkins University (IO), 353

STRESS TESTING Long-term Prognostic Value of Dobutamine Stress Echocardiography Compared with Myocardial Perfusion Scanning in Patients Unable to Perform Exercise Tests, 1

ST DEPRESSION ST Depression as a Long-term Risk Predictor in the Era of Invasive Management of Coronary Syndromes (E), 200

STROKE Application of U.S. Guidelines in Other Countries: Aspirin for the Primary Prevention of Cardiovascular Events in Japan, 459 December 15, 2004

SUBSPECIALTY FELLOWSHIP RECRUITMENT Halfway Toward Healing a Broken System: Fellowship Recruitment in Internal Medicine (APM), 69 SUDDEN DEATH Temporal Trends in the Incidence of Coronary Disease, 228 SURROGATE DECISION-MAKER CHARACTERISTICS The Relation of Autopsy Rate to Physicians’ Beliefs and Recommendations Regarding Autopsy, 255 SURVIVAL Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 Sex-Based Comparison of Survival in Referred Patients with Hypertrophic Cardiomyopathy (LE), 65 SWEAT GLAND NECROSIS Pressure-induced Bullae and Sweat Gland Necrosis Following Chemotherapy Induction (LE), 441

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Subject Index

SYNOVIAL FLUID ANALYSIS Synovial Fluid Leukocyte Count and Differential for the Diagnosis of Prosthetic Knee Infection, 556 SYPHILIS Cases from the Osler Medical Service at Johns Hopkins University (IO), 871 SYSTEMATIC REVIEWS Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 Systematic Reviews of Herbal Medicines (LE), 533 SYSTEMIC LUPUS ERYTHEMATOSUS Incidence and Predictors of Renal Disease in Chinese Patients with Systemic Lupus Erythematosus (BO), 791 T-WAVE INVERSION Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145 ST Depression as a Long-term Risk Predictor in the Era of Invasive Management of Coronary Syndromes (E), 200 TAI CHI Benefits of Tai Chi in Chronic Heart Failure: Body or Mind? (E), 611 Effects of Tai Chi Mind-Body Movement Therapy on Functional Status and Exercise Capacity in Patients with Chronic Heart Failure: A Randomized Controlled Trial, 541 TEACHING HOSPITALS Effects of Weekend Admission and Hospital Teaching Status on In-hospital Mortality, 151 The Future of Financing Medical Education: Questions About Medicare’s Role (APM), 287 TELOMERE MAINTENANCE Telomere Maintenance in Clinical Medicine (R), 262 THALIDOMIDE Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 1008

December 15, 2004

THIAZOLIDINEDIONES Insulin Resistance and the Endothelium (R), 109

The Further Evolution of Hyperparathryoidism: Implications for Clinical Care (E), 884

Pioglitazone-induced Heart Failure Despite Normal Left Ventricular Function (LE), 973

Thyroid Disorders in Chronic Hepatitis C, 10

THROMBOCYTOPENIA Life Expectancy and Prognostic Factors for Survival in Patients with Polycythemia Vera and Essential Thrombocytopenia, 755 THROMBOEMBOLIC COMPLICATIONS Dyspnea in a Woman with a Permanent Pacemaker (LE), 535

TRAINING Modernizing the Paths to Certification in Internal Medicine and Its Subspecialties (E), 133 TRANSITIONAL CARE The Last Day of the Past Is the First Day of the Future: Transitional Care for Genetic Patients (E), 615

Risk of Serious Upper Gastrointestinal and Cardiovascular Thromboembolic Complications with Meloxicam, 100

TRANSPLANTATION The Net Transfer Organs across Race, Sex, Age, and Income, 670

THROMBOEMBOLISM Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19

TREATMENT RECOMMENDATIONS Effects of Treatment Recommendations and Specialist Intervention on Care Provided by Primary Care Physicians to Patients with Myocardial Infarction or Heart Failure, 371

Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 Venous Thromboembolism in Pregnancy: 21-Year Trends (BO), 121 Why Not Test for Hypercoagulability in Patients with Idiopathic Venous Thromboembolism (LE), 801 THROMBOPOIETIN Danazol, Idiopathic Thrombocytopenic Purpura, and Thrombopoietin (LE), 972 THROMBOSIS Deep Vein Thrombosis and Pulmonary Embolism in Two Cohorts: The Longitudinal Investigation of Thromboembolism Etiology, 19 THYROID AUTOIMMUNITY Hepatitis C and Thyroid Autoimmunity: Is There a Link? (E), 60 THYROID FUNCTION Characterization of Normocalcemic Primary Hyperparathyroidism (BO), 861 Disturbed Metabolism of Remnant Lipoproteins in Patients with Subclinical Hypothyroidism (BO), 696

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TREATMENT-RESISTANT TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PERIODIC SYNDROME Beneficial Response to Interleukin 1 Receptor Antagonist in Traps (LE), 208 TRICUSPID REGURGITATION Platypnea-Orthodeoxia Syndrome Occurring After a Blunt Chest Trauma with Acute Tricuspid Regurgitation (LE), 890 TROPONIN Baseline Troponin in Acute Coronary Syndromes Managed Invasively (E), 963 Prognostic Value of Quantitative Troponin T Measurements in Unstable Angina/ Non-ST-Segment Elevation Acute Myocardial Infarction Treated Early and Predominantly with Percutaneous Coronary Intervention, 897 TUBERCULOMA Spinal Cord Compression From Intradural Extramedullary Tuberculoma (LE), 620 TUMOR NECROSIS FACTOR (TNF)-␣ Refractory Neurosarcoidosis: A Dramatic Response to Infliximab (LE), 277

Subject Index

ULTRASOUND Low Sensitivity of Ultrasonography for the Early Diagnosis of Amebic Liver Abscess (BO), 519 UNILATERAL TRANSUDATIVE PLEURAL EFFUSION Unilateral Transudative Pleural Effusion: An Exceptional Cause (LE), 888 UNSTABLE ANGINA/NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION Prognostic Value of the Admission Electrocardiogram in Patients with Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction Treated with Very Early Revascularization, 145 URINARY TRACT INFECTION Predictors of Urinary Tract Infection after Menopause: A Prospective Study, 903 UROSEPSIS Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 UTILIZATION MANAGEMENT Utilization Management: A Bad Review (E), 703 VA MEDICAL AND PROSTHETICS RESEARCH PROGRAM The Future of Federal Funding for Medical Research: APM Recommendations (APM), 213 VACCINES Availability of Large-Scale Evidence on Specific Harms from Systematic Reviews of Randomized Trials, 582 VASCULAR FUNCTION Effects of Statins on Vascular Structure and Function: A Systematic Review, 775 VASCULAR GRAFTS Benefits of Antithrombotic Therapy After Infrainguinal Bypass Grafting: A MetaAnalysis, 93 VASCULAR PARKINSONISM Clinical Differentiation of Parkinsonian Syndromes: Prognostic and Therapeutic Relevance (R), 412

VASCULAR STRUCTURE Effects of Statins on Vascular Structure and Function: A Systematic Review, 775 VASCULITIDES The Antineutrophil Cytoplasmic Antibody-Associated Vasculitides (R), 39 VASCULITIS Pulmonary Artery Aneurysms in Behc¸et Syndrome (BO), 867 VENOUS THROMBOEMBOLISM Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 676

nin, Alfacalcidol, and Vitamin K in Postmenopausal Women with Osteoporosis: The Yamaguchi Osteoporosis Prevention Study, 549 WALDENSTROM MACROGLOBULINEMIA Adverse Effects of Thalidomide Administration in Patients with Neoplastic Diseases, 508 WANDERLUST The End of Wanderlust (LE), 66

Venous Thromboembolism in Pregnancy: 21-Year Trends (BO), 121

WEEKEND ADMISSION Effects of Weekend Admission and Hospital Teaching Status on In-hospital Mortality, 151

Why Not Test for Hypercoagulability in Patients with Idiopathic Venous Thromboembolism (LE), 801

WEEKEND CARE Should U.S. Hospitals Go 24/7? (E), 202

VENTRICULAR FUNCTION Transient Cardiac Dysfunction in Acute Carbon Monoxide Poisoning (LE), 623 VENTRICULAR TACHYCARDIA Death Certificate Completion: How Well Are Physicians Trained and Are Cardiovascular Causes Overstated?, 492 VETERANS Association of Body Weight with Condition-Specific Quality of Life in Male Veterans, 738 Blunted Circadian Variation in Autonomic Regulation of Sinus Node Function in Veterans with Gulf War Syndrome, 469 Cardiac Autonomic Dysfunction in Gulf War Syndrome: Veterans Hearts Don’t Rest at Night (E), 531 Do Aspirin and Nonsteroidal Anti-inflammatory Drugs Cause False-positive Fecal Occult Blood Test Results? A Prospective Study in a Cohort of Veterans, 837 VITAMIN A Serum Vitamin A Concentration and the Risk of Hip Fracture among Women 50 to 74 Years Old in the United States: A Prospective Analysis of the NHANES I Follow-up Study, 169 VITAMIN K Comparative Efficacy of Hormone Replacement Therapy, Etidronate, CalcitoDecember 15, 2004

Waiting for Urgent Procedures on the Weekend among Emergently Hospitalized Patients, 175 WEGENER’S GRANULOMATOSIS The Antineutrophil Cytoplasmic Antibody-Associated Vasculitides (R), 39 WEIGHT LOSS INTERVENTIONS Long-term Effectiveness of Lifestyle and Behavioral Weight Loss Interventions in Adults with Type 2 Diabetes: A Metaanalysis, 762 WELLS PREDICTION RULES Usefulness of Clinical Prediction Rules for the Diagnosis of Venous Thromboemolism: A Systematic Review (R), 677 WERNICKE ENCEPHALOPATHY Wernicke Encephalopathy—An Emerging Trend After Bariatric Surgery (LE), 804 WORKPLACES Cardiovascular Health and Economic Effects of Smoke-Free Workplaces, 32 WORKWEEK Can Residents Be Professional in 80 or Fewer Hours a Week?, 846 A Case for the 80 Duty-hour Week, 879 WORMS The End of Wanderlust (LE), 66

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