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Contents
CONTENTS CONTINUED
Reviews and feature articles Current reviews of allergy and clinical immunology
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w CME
Asthma, influenza, and vaccination
1199
W. Paul Glezen, MD, Houston, Tex
Continuing Medical Education examination: Asthma, influenza, and vaccination 1207 Molecular mechanisms in allergy and clinical immunology
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w CME
Biologic immune modifiers: Trials and tribulations—are we there yet?
1209
Mark Ballow, MD, Buffalo, NY
Continuing Medical Education examination: Biologic immune modifiers: Trials and tribulations—are we there yet?
1216
Asthma diagnosis and treatment Original articles Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide
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1218
Anne M. Fitzpatrick, PhD, Benjamin M. Gaston, MD, Serpil C. Erzurum, MD, and W. Gerald Teague, MD, for the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program, Atlanta, Ga, Charlottesville, Va, and Cleveland, Ohio
Children with severe asthma have unique features compared with children with mildto-moderate asthma. These features may be easily identified by pulmonary function tests and noninvasive measures of atopy and airway inflammation.
Continued on page 12A The Journal of Allergy and Clinical Immunology posts in-press articles online in advance of their appearance in the print edition of the Journal. They are available at the JACI Web site at www.jacionline.org at the ‘‘Articles in Press’’ link, as well as at Elsevier’s ScienceDirect Web site, www.sciencedirect.com. Each print article will acknowledge the e-publication date (the date when the article first appeared online). As soon as an article is published online, it is fully citable through use of its Digital Object Identifier (DOI). Please visit the JACI Web site and view our hot-off-the-wire articles through the ‘‘Articles in Press’’ link.
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Editors’ Choice (p 1197)
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Online Repository material
m
Video available online at www.jacionline.org
Y
Theme article
V
w CME
CME activity available online at www.jacionline.org
10A December 2006
J ALLERGY CLIN IMMUNOL
CONTENTS CONTINUED
Reviews and feature articles Current reviews of allergy and clinical immunology
Y
w CME
Asthma, influenza, and vaccination
1199
W. Paul Glezen, MD, Houston, Tex
Continuing Medical Education examination: Asthma, influenza, and vaccination 1207 Molecular mechanisms in allergy and clinical immunology
Y
w CME
Biologic immune modifiers: Trials and tribulations—are we there yet?
1209
Mark Ballow, MD, Buffalo, NY
Continuing Medical Education examination: Biologic immune modifiers: Trials and tribulations—are we there yet?
1216
Asthma diagnosis and treatment Original articles Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide
OR d
1218
Anne M. Fitzpatrick, PhD, Benjamin M. Gaston, MD, Serpil C. Erzurum, MD, and W. Gerald Teague, MD, for the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program, Atlanta, Ga, Charlottesville, Va, and Cleveland, Ohio
Children with severe asthma have unique features compared with children with mildto-moderate asthma. These features may be easily identified by pulmonary function tests and noninvasive measures of atopy and airway inflammation.
Continued on page 12A The Journal of Allergy and Clinical Immunology posts in-press articles online in advance of their appearance in the print edition of the Journal. They are available at the JACI Web site at www.jacionline.org at the ‘‘Articles in Press’’ link, as well as at Elsevier’s ScienceDirect Web site, www.sciencedirect.com. Each print article will acknowledge the e-publication date (the date when the article first appeared online). As soon as an article is published online, it is fully citable through use of its Digital Object Identifier (DOI). Please visit the JACI Web site and view our hot-off-the-wire articles through the ‘‘Articles in Press’’ link.
EC d
Editors’ Choice (p 1197)
OR d
Online Repository material
m
Video available online at www.jacionline.org
Y
Theme article
V
w CME
CME activity available online at www.jacionline.org
10A December 2006
J ALLERGY CLIN IMMUNOL