The occurrence of eosinophiles in the secretions from the nose, the sinuses and the tonsils

312

THE

JO'URNXL

OF ALLERGY

chiefly as to time: (1) the immediate reaetioi~-reddelImg, wheal formation, usually disappearing after one how ; (2) the late reactioIl--reddening and moderate tissue infiltration, reaching its lnaxilliurll oni> after twenty-four hours and usually persisting several days. ROih Exreactions can be considered as different degrees of sensitization. periments showed that, when a normal child is sensitized with small doses, parenterally, at daily intervals, the following stages of skill reactions are observed in this order: intracutaneous late reaction, intracutaneous immediate reaction plus late reaction, and then intracutaneous immediate reaction and no late reaction. /Late reaction := taberculin type reaction.]

Otolaryngology UNDER,

THE

DIRE'CTIOS

OF

FRENCH

K.

HA4~s2~,

N.D.;

ST.

LOUIS

rrence of Eosinophiles in the and the Tonsils. KaMs, P. : Kall6s made a study of 125 cases of nasal and tonsil!ar diseases in which the secretions were examined for eosinophiles. Iii the nasal cases, consisting of vasomotor rhinitis and nasal polyps, eosinophiles were found to be present in the secretions from 10 to 50 per cent,. An :osinophilia was also demonstrated in secretions expressed from the tonsils in rheumatic patients. Definite eosinophilia was also demonstrated in the tonsils upon histologic examination. Similar studies in nonrheumatic patients reyealed no eosinophilia. Kallb suggests a possible association between the tonsils and rheuma,tism on the basis of the local eosinophilia. These findings also suggest, perhaps, the allergic basis of rheumatism.

sefulness of Nasal Symptoms and de Graaf, a.:

Acta oto-laryng.

in Hay Fever.

Rei~jamins,

“cr. li:.,

20: 165, 1934.

In a study of the nature of the local nasal reaction concerned in hay fever, Benjamins and de Graaf carried out a series of experiments. They concerned a comparative examination of the sensitivity of the skin, the nasal mucosa, and the conjunetiva to the active substance of pollen. The problem also concerned the inrrestigation of the absorption of the active substance by the nasal mucosa and also the quantity of pollen likely to be found in the nose during the period of pollinat,iol~ of grasses. As a result of the experiments, it was shown that the slrin is genera.lly much more sensitive to the active principle of pollen l-harr i;ile nasal mucosa, but the absorption of the n.ctive substance by the