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Tongue somatosensory evoked potentials in microvascular decompression treated trigeminal neuralgia
Abstracts / Journal of the Neurological Sciences 333 (2013) e579–e628
Abstract — WCN 2013 No: 234 Topic: 36 — Other Topic Comparison of brain wave patterns in aggressive and non aggressive subjects M. Abdollahia, P. Ahmadib, P. Mazujib, S. Poorhassanb. aYoung Researchers and Elite Club, Islamic Azad University, Tabriz Branch, Tabriz, Iran; bDepartment of Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran Background and objectives: Human aggression is an important social and clinical problem. There are many studies in determining the criteria for diagnosis and assessment of aggression. The aim of this study was to study aggressive subject's brain wave activity compared with healthy subjects by qEEG. Materials and methods: The research method was contrastive– descriptive over which some 30 people of aggressive persons compared and contrasted with some 30 nonaggressive persons were demographically similar to aggressive group. The artifact free EEG epoch was analyzed by fast Fourier transformation (FFT) and power values of particular frequency bands (delta, theta, alpha and beta) were observed on the brain regions. Results and conclusion: Results of variance analysis showed that aggressive subjects' theta activity in frontal, central, parietal and temporal areas is lower than normal subjects. In addition there is an increase in beta activity in frontal, central, parietal and temporal areas compared with nonaggressive subjects. These results suggest that the disorder changes the brain wave activity.
e583
Abstract — WCN 2013 No: 271 Topic: 36 — Other Topic Reduce the risk in vulnerability in HIV E. Philip. University of Ghana, Accra, Ghana Background: Before the people can reduce the risk and vulnerability to HIV, individuals and communities must understand the urgency to the epidemic. They must be given basic facts about HIV/aids, taught set of protective skills and offered access to appropriate services and products. Methods: A cross sectional community based survey has been conducted between January 2011 and April 2011 by interview of 419 heads of the households regarding the knowledge of HIV transmission means in Accra, Ghana. Results: Out of the interviewed 419 household heads, 287 (68.5%) were females. 36%, 28% and 34.3% were in the age group of 40+, 31–40 and 15–30 respectively. The findings revealed that only 21 (5%) of study participants mentioned four ways of HIV transmission (unprotected sex, mother to child, sharp materials and blood transfusion). On the other hand, 63 (15%) mentioned any three of the above route of transmission, whereas the majority, 209 (50%) and 86 (20.5%) mentioned two and one means of HIV respectively. On contrary about 40 (10%) of interviewed heads of household mentioned hardly any of the transmission means. Males were about 2.4 times more likely to mention unprotected sex as one means of transmission than females. Conclusion: In general, knowledge of residents of Medina in the capital town of Ghana about HIV transmission and prevention means was low. Appropriate HIV/Aids education means ought to be tailored to residents.
doi:10.1016/j.jns.2013.07.2035
doi:10.1016/j.jns.2013.07.2037
Abstract — WCN 2013 No: 258 Topic: 36 — Other Topic Tongue somatosensory evoked potentials in microvascular decompression treated trigeminal neuralgia
Abstract — WCN 2013 No: 280 Topic: 36 — Other Topic Ineffectiveness of topiramate and levetiracetam in infantile spasms non-responsive to steroids
M. Krbot Skorića, I. Adameca, G. Grahovacb, D. Chudyb, S. Hajnšeka, M. Habeka. aUniversity Hospital Center Zagreb, Croatia; bClinical Hospital Dubrava, Zagreb, Croatia
A.A. Mahmoud. Pediatric Neurology, KFMC, Riyadh, Saudi Arabia
Background: Somatosensory evoked potentials of the tongue (tSSEP) provide useful information about trigeminal afferent pathway. The aim of this study was to evaluate tSSEP in trigeminal neuralgia treatment with microvascular decompression. Methods: Two patients with trigeminal neuralgia refractory to conservative treatment underwent microvascular decompression of the trigeminal nerve. tSSEP was performed a month prior to surgery and in the month after the surgery in both patients. Pain frequency and tSSEP were analyzed before and after surgery. Results: In both patients a complete resolution of pain occurred. In patient 1, tSSEP latencies became shorter then before surgery and wave N1 appeared. The intensity of stimulation necessary to reach the threshold was 4 mA before the surgery and 1 mA after the surgery. A complete recovery of tSSEP after the operation was achieved in patient 2. Conclusions: The results of present study demonstrate the value of tSSEP in the evaluation of trigeminal conduction recovery after microvascular decompression.
doi:10.1016/j.jns.2013.07.2036
Objectives: To compare the effectiveness of 2 novel antiepileptic drugs Topiramate and Levetiracetam as a second line treatment for infantile spasm when oral steroids fail. Methods: Forty infants within 2 years of life with clinically- and EEG-proven infantile spasms that did not respond to prednisone (2 mg/kg/day in 2 divided doses) were recruited and randomized into 2 groups. They were randomly assigned to either Topiramate (group 1; 1 mg/kg/day for 3 days then increased by 1 mg/kg/day every 3rd day up to 6 mg/kg/day) or Levetiracetam, (group 2; 10 mg/kg/day for 5 days and then increased by 10 mg/kg/day every 5 days up to 60 mg/kg/day). Results: Of the 20 patients included in the final data analysis, 11 (55%) were administered with Topiramate and 9 (45%), Levetiracetam. Eighteen patients did not respond to the first drug and subsequently to the other drug when crossed-over, if the first drug proved ineffective. Two patients with infantile spasm responded to either one drug respectively without crossover. Their EEGs improved with time. In accordance with Helsinki Declaration and Belmont Report Ethical codes, we stopped recruitment at 20 patients due to the ineffectiveness of both drugs. Thus, only 20 children were included in final data analysis. Conclusion: The present study demonstrated the ineffectiveness of Topiramate and Levetiracetam suggesting that current treatment modalities are grossly inadequate underscoring the urgent need for more research efforts to overcome current deficiencies. Two patients with cryptogenic infantile spasm responded to treatment suggesting
Abstract — WCN 2013 No: 234 Topic: 36 — Other Topic Comparison of brain wave patterns in aggressive and non aggressive subjects M. Abdollahia, P. Ahmadib, P. Mazujib, S. Poorhassanb. aYoung Researchers and Elite Club, Islamic Azad University, Tabriz Branch, Tabriz, Iran; bDepartment of Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran Background and objectives: Human aggression is an important social and clinical problem. There are many studies in determining the criteria for diagnosis and assessment of aggression. The aim of this study was to study aggressive subject's brain wave activity compared with healthy subjects by qEEG. Materials and methods: The research method was contrastive– descriptive over which some 30 people of aggressive persons compared and contrasted with some 30 nonaggressive persons were demographically similar to aggressive group. The artifact free EEG epoch was analyzed by fast Fourier transformation (FFT) and power values of particular frequency bands (delta, theta, alpha and beta) were observed on the brain regions. Results and conclusion: Results of variance analysis showed that aggressive subjects' theta activity in frontal, central, parietal and temporal areas is lower than normal subjects. In addition there is an increase in beta activity in frontal, central, parietal and temporal areas compared with nonaggressive subjects. These results suggest that the disorder changes the brain wave activity.
e583
Abstract — WCN 2013 No: 271 Topic: 36 — Other Topic Reduce the risk in vulnerability in HIV E. Philip. University of Ghana, Accra, Ghana Background: Before the people can reduce the risk and vulnerability to HIV, individuals and communities must understand the urgency to the epidemic. They must be given basic facts about HIV/aids, taught set of protective skills and offered access to appropriate services and products. Methods: A cross sectional community based survey has been conducted between January 2011 and April 2011 by interview of 419 heads of the households regarding the knowledge of HIV transmission means in Accra, Ghana. Results: Out of the interviewed 419 household heads, 287 (68.5%) were females. 36%, 28% and 34.3% were in the age group of 40+, 31–40 and 15–30 respectively. The findings revealed that only 21 (5%) of study participants mentioned four ways of HIV transmission (unprotected sex, mother to child, sharp materials and blood transfusion). On the other hand, 63 (15%) mentioned any three of the above route of transmission, whereas the majority, 209 (50%) and 86 (20.5%) mentioned two and one means of HIV respectively. On contrary about 40 (10%) of interviewed heads of household mentioned hardly any of the transmission means. Males were about 2.4 times more likely to mention unprotected sex as one means of transmission than females. Conclusion: In general, knowledge of residents of Medina in the capital town of Ghana about HIV transmission and prevention means was low. Appropriate HIV/Aids education means ought to be tailored to residents.
doi:10.1016/j.jns.2013.07.2035
doi:10.1016/j.jns.2013.07.2037
Abstract — WCN 2013 No: 258 Topic: 36 — Other Topic Tongue somatosensory evoked potentials in microvascular decompression treated trigeminal neuralgia
Abstract — WCN 2013 No: 280 Topic: 36 — Other Topic Ineffectiveness of topiramate and levetiracetam in infantile spasms non-responsive to steroids
M. Krbot Skorića, I. Adameca, G. Grahovacb, D. Chudyb, S. Hajnšeka, M. Habeka. aUniversity Hospital Center Zagreb, Croatia; bClinical Hospital Dubrava, Zagreb, Croatia
A.A. Mahmoud. Pediatric Neurology, KFMC, Riyadh, Saudi Arabia
Background: Somatosensory evoked potentials of the tongue (tSSEP) provide useful information about trigeminal afferent pathway. The aim of this study was to evaluate tSSEP in trigeminal neuralgia treatment with microvascular decompression. Methods: Two patients with trigeminal neuralgia refractory to conservative treatment underwent microvascular decompression of the trigeminal nerve. tSSEP was performed a month prior to surgery and in the month after the surgery in both patients. Pain frequency and tSSEP were analyzed before and after surgery. Results: In both patients a complete resolution of pain occurred. In patient 1, tSSEP latencies became shorter then before surgery and wave N1 appeared. The intensity of stimulation necessary to reach the threshold was 4 mA before the surgery and 1 mA after the surgery. A complete recovery of tSSEP after the operation was achieved in patient 2. Conclusions: The results of present study demonstrate the value of tSSEP in the evaluation of trigeminal conduction recovery after microvascular decompression.
doi:10.1016/j.jns.2013.07.2036
Objectives: To compare the effectiveness of 2 novel antiepileptic drugs Topiramate and Levetiracetam as a second line treatment for infantile spasm when oral steroids fail. Methods: Forty infants within 2 years of life with clinically- and EEG-proven infantile spasms that did not respond to prednisone (2 mg/kg/day in 2 divided doses) were recruited and randomized into 2 groups. They were randomly assigned to either Topiramate (group 1; 1 mg/kg/day for 3 days then increased by 1 mg/kg/day every 3rd day up to 6 mg/kg/day) or Levetiracetam, (group 2; 10 mg/kg/day for 5 days and then increased by 10 mg/kg/day every 5 days up to 60 mg/kg/day). Results: Of the 20 patients included in the final data analysis, 11 (55%) were administered with Topiramate and 9 (45%), Levetiracetam. Eighteen patients did not respond to the first drug and subsequently to the other drug when crossed-over, if the first drug proved ineffective. Two patients with infantile spasm responded to either one drug respectively without crossover. Their EEGs improved with time. In accordance with Helsinki Declaration and Belmont Report Ethical codes, we stopped recruitment at 20 patients due to the ineffectiveness of both drugs. Thus, only 20 children were included in final data analysis. Conclusion: The present study demonstrated the ineffectiveness of Topiramate and Levetiracetam suggesting that current treatment modalities are grossly inadequate underscoring the urgent need for more research efforts to overcome current deficiencies. Two patients with cryptogenic infantile spasm responded to treatment suggesting