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Use of typhoid vaccine in treatment of chorea: Its possible dangers
there most
was immediate of the collat,eral
Xcupham,
G. W.,
and
and complete cure; branches entering
de Takats,
G:.:
Peripheral
Some of the Recent Literature With Arch. Int. Med. 56: 530, 1935.
ease it was necessary artery to complete
in the other the ophthalmic
a Critical
Vascular
Diseases.
Review
of Surgical
to excise the cure. E. A.
A Beview
of
Treatment.
The review is in two parts; the first, :tn excellent presentation of tile salient features of the many recent advances in the general field of the peripheral circulation, the second, a surgeon’s critical summary of most of the surgical aspects of treatment. By far the greater part of the work reviewed has been done in the past five years; its extent is indicated by the use of 90 pages of the journal for an exceedingly meaty consideration of some 260 articles. In the field of the physiology of the peripheral circulation Sir Thomas Lewis is being followed by several able investigators. Most important advances have been made in the field of conservative therapy based on new physiologicd discoveries. Furthermore, as the various disorders are better understood and are diagnosed earlier, much of the previous therapy is being discarded. The operation of periarterial sympathectomy, for instance, is being limited much more strictly than in the early days of enthusiasm. The etiology of Buerger’s disease remains unsolved, but its early recognition and treatment art~o= aided by recent investigation. L. H. H. Liu, am.
A. C., and Eosenbluetb, J. Physiol.
113:
X%,
A.:
Eeflex
Liberation
of
Circulating
Sympathin.
1935.
Direct stimulation of sympathetic nerves leads to the passage into the Mood of sympathin, a sympathomimetic substanca the presence of which may be demonstrated by reactions of adequate denervated autonomic effecters. The question arises, Can reflex activation of sympathetic nerves cause sympathin to pass into the blood? :!ontrolled experiments on cats show that stimulation of the sciatic or one of the brachial nerves causes contraction of the nictating membra.ne, a manifestation of While sympathin origcirculating sympathin under conditions of the experiment. mates from sympathetic nerves, its presence in the blood in the experiments did not depend upon certain parts of the sympathetic nervous system, as contractions of the nictating membrane occurred when the thoracie sympatheties were present and the cephalic and abdominal sympathetics were absent, as well as when conditions were reverse. It appears that sympathin may play a r61e 3s a hormone in certain physiological conditions. E. A,
Ash, Rachel: Use of Typhoid Vaccine in Treatment Dangers, Am. J. Dis. Child. 50: 879, 1935.
of
Ghorea;
Its
SPossible
intravenous injections of typhoid vaccine may be of I~;trni in the presence of carditis. During the febrile reaction follon;ng intravenous injections of typhoid vaccine, there is a depression of granulocytes. This method of therapy should be checked by frequent determinations of the vvhite blood cell count. Typhoid vaccine therapy does not prevent a recurrence of chorea.
was immediate of the collat,eral
Xcupham,
G. W.,
and
and complete cure; branches entering
de Takats,
G:.:
Peripheral
Some of the Recent Literature With Arch. Int. Med. 56: 530, 1935.
ease it was necessary artery to complete
in the other the ophthalmic
a Critical
Vascular
Diseases.
Review
of Surgical
to excise the cure. E. A.
A Beview
of
Treatment.
The review is in two parts; the first, :tn excellent presentation of tile salient features of the many recent advances in the general field of the peripheral circulation, the second, a surgeon’s critical summary of most of the surgical aspects of treatment. By far the greater part of the work reviewed has been done in the past five years; its extent is indicated by the use of 90 pages of the journal for an exceedingly meaty consideration of some 260 articles. In the field of the physiology of the peripheral circulation Sir Thomas Lewis is being followed by several able investigators. Most important advances have been made in the field of conservative therapy based on new physiologicd discoveries. Furthermore, as the various disorders are better understood and are diagnosed earlier, much of the previous therapy is being discarded. The operation of periarterial sympathectomy, for instance, is being limited much more strictly than in the early days of enthusiasm. The etiology of Buerger’s disease remains unsolved, but its early recognition and treatment art~o= aided by recent investigation. L. H. H. Liu, am.
A. C., and Eosenbluetb, J. Physiol.
113:
X%,
A.:
Eeflex
Liberation
of
Circulating
Sympathin.
1935.
Direct stimulation of sympathetic nerves leads to the passage into the Mood of sympathin, a sympathomimetic substanca the presence of which may be demonstrated by reactions of adequate denervated autonomic effecters. The question arises, Can reflex activation of sympathetic nerves cause sympathin to pass into the blood? :!ontrolled experiments on cats show that stimulation of the sciatic or one of the brachial nerves causes contraction of the nictating membra.ne, a manifestation of While sympathin origcirculating sympathin under conditions of the experiment. mates from sympathetic nerves, its presence in the blood in the experiments did not depend upon certain parts of the sympathetic nervous system, as contractions of the nictating membrane occurred when the thoracie sympatheties were present and the cephalic and abdominal sympathetics were absent, as well as when conditions were reverse. It appears that sympathin may play a r61e 3s a hormone in certain physiological conditions. E. A,
Ash, Rachel: Use of Typhoid Vaccine in Treatment Dangers, Am. J. Dis. Child. 50: 879, 1935.
of
Ghorea;
Its
SPossible
intravenous injections of typhoid vaccine may be of I~;trni in the presence of carditis. During the febrile reaction follon;ng intravenous injections of typhoid vaccine, there is a depression of granulocytes. This method of therapy should be checked by frequent determinations of the vvhite blood cell count. Typhoid vaccine therapy does not prevent a recurrence of chorea.