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0242 Mechanisms of myofascial trigger point
Poster Abstracts
Monday, November 7, 2005
S161
Fumagalli, AI ~, Saredo G 2. 1Sanatorio Parque, Rosario, Argentina,"
Plummet, C ~, Vellar, I t , Cook, MJ 1. 1St Vineent's Hospital, Melbourne,
2Hospital Iturraspe, San ta Fe, Argentina
Australia.
Background: Historical evidence illustrates how Christofredo Jakob contributed to Neurosciences in Argentina. Method: Review of primary source documents from the XIX and X X centuries. Results: The most famous Argenrinian neurologist a n d the father of neuropsychiatry was Jos~ Maria R a m o s Mejia (1849-1914), "The R a m o s Mejia Hospital" perpetuates Iris name, one of his students was Jos~ A. Esttvez.Christofredo Jakob (1866-1956) was born in W~rnitz-Ostheim, G e r m a n y and h a d started Iris academic career under Adolf yon Stfftimpell's guidance. He lived and worked a lot in Argentina since 1889 up to his death. He was a great neuropathologist and from a neurobiological point o f view there are important papers of him dealing with the origin of the cerebral cortex from the striatum and the entortfinal areas. His students have been famous after lfim like Braulio M o y a n o and Vicente Dimitri, a pioneer in studies of the clinico-pathological correlations, who had visited European hospitals and became a very well-known professor of Neurology at the National University in 1941. Sturge-Weber syndrome has also been described as Sturge-Weber-Dimitri, because he h a d described previous cases in 1923. All of them were impressed and influenced by French Neurology. Conclusion: "To see in every day and year a symbol of all the days of m a n and his years, and convert the outrage of the years into a music., a sound, and a symbol..." Jorge Lnis Borges, The Hacedor
Aim: To review Australia's first intracranial meningioma resection; and to investigate the circumstances of the patient's death. Background: George Syme performed Australia's first documented meningioma resection in 1894 at St Vincent's Hospital, Melbourne. It followed Victor Horsley's first neurosurgical case by only 8 years. Although Syme's operation was successful, his patient died years later in unusual circumstances. Methods: The archives at St Vincent's Hospital, The Australasian College of Surgeons, and The Public Record Office Victoria were searched. The case notes by George Syme's assistant and the inquest proceedings into John Gleeson's death were examined. Results: A " t u m o u r the size of a tangerine orange" was removed from the left frontoparietal convexity of 30-year-old John Gleeson, a policeman. Gleeson presented with sensorimotor seizures before later developing symptoms of raised intracranial pressure. "rite patient recovered and his seizures resolved. In 1917 Gleeson died from an apparent gunshot to the head. A broken chair and a revolver were in the room. Gleeson's son h a d allegedly left the house earlier calling "that his father was shooting lfimself". The Coroner judged " t h a t the death (was) due to accident". Discussion: The operative notes reconfirm George Ssane's skill as a meticulous historian and surgeon. His pre-surgical localisation of the tumour is remarkable. The Coroner's decision does n o t appear to fully account for all the available testimony. Conclusion: George Syme performed a landmark operation 111 years ago on a y o u n g policeman whose later death adds an interesting epilogue to a piece o f Australian neurosurgical history.
0238 National Institute of Neurology, Russian Academy of Medical Sciences: 60 Years Suslina, Z 1, marioshkin, S z, Piradov, M a, Tanashyan, M 1. JNationa[ Institute of Neurology, P~ssian Academy of Medical Sciences, Ivloscow, Russia National Institute of Neurology of the Russian A c a d e m y of Medical Sciences was established on April 1, 1945. For 60 years it has been a leading research neurological institution in Russia and U S S R engaged in studies of most c o m m o n and severe diseases o f the nervous system. If was headed by brilliant neurologists N.Grashchenkov, N. Konovalov (student of a famous Russian neurologist Rossolimo), E. Shmidt, N. Vereshchagin. Just after the Second World War, research interests of the Institute were focused on traumatic injuries o f the head and nerves (as a consequence of the war). In the 1950s, the Institute was engaged in studies o f poliomyelitis, which resulted in creation of a s p edfic vaccine and virtual liquidation of the disease in U S S R (M.Tchumakov), as well as in the development of technologies of many-years artificial ventilation (L. Popova). Later, the Institute started research on cerebrovascular disorders, neurodegenerative disorders, neurogenetics and critical care in neurology. In amyotrophic lateral sclerosis, there is a well-known term " B u n i n a bodies", specific intraneuronal inclusions described in the 1960s by Dr. T. Bunina working in the Institute. Institute of Neurology m a d e significant contribution to studies of cerebrovascular disorders especially in the field of their hemorheologic and cardiac basis, Sneddoffs syndrome, problems of stroke heterogeneity, etc. Neurologists from the Institute described several new forms of hereditary neurological disorders and identified m u t a n t lod by linkage analysis. At present, the Institute is a regional W H O center in neurosciences coordinating research and educational activities in neurology in Russia and other countries of the CIS (former Soviet Union).
0239 "A twist in tile tale" of a surgeon and his patient
0241 Tile Billings Method - an Australian Neurologists story Tubridy, N ~. 1Department of Neurology, St. Vincent's University
Hospital, Ebn Park, Dublin d, Republic of Ireland Background: The Billings Ovulation Method of fanfily planning celebrated its 50± anniversary in 2003. The method is still practiced throughout the world today and was devised by Dr. JJ Billings a n d Iris wife Dr. Evelyn Billings in Melbourne, Australia. Dr. Billings was one of the first neurologists in Melbourne and was a pioneer in the field of Australian Neurology. Dr. Billings" extraordinary life a n d career is chronicled a n d h o w a single-handed neurologist aclfieved world renown in the field of family planning is discussed.
0242 MechatdmlS of myofascial trigger pOhlt Devlikamova, F. Kazan State Medical Academy, Department of
Neurology and Spinal Disorders, Kazan, Tatarstan, Russia Objectives: The aim o f this study was to evaluate the mechanisms of myofascial trigger point (TrP) formation. Methods: Sixteen patients with myofascial pain syndrome, caused by TrP in trapezius muscle, and 12 age-matched controls were included in this study. The trapezius muscle was examined by m e a n s of single fiber and concentric needle electrodes (Keypoint, Dante@ Muscle needle biopsies were studied by electron microscope. Results: The investigation showed changes in the shape of the main spike motor unit and endplate potentials, decrease in the duration and amplitude of motor unit potentials, increase in the duration and rise time endplate potentials in m y o f a s d a l TrP. In patients, the fibre density was increased in the TrP - 2.05, SD 0.26 [control- 1.48, SD 0.3; P < 0.01]. Mean values of consecutive differences o f the TrP is higher than that in control group. The destruction o f contractile apparatus that we observed involves myofibrils loss and broadened interfibrillar distance. In some parts of
Monday, November 7, 2005
S161
Fumagalli, AI ~, Saredo G 2. 1Sanatorio Parque, Rosario, Argentina,"
Plummet, C ~, Vellar, I t , Cook, MJ 1. 1St Vineent's Hospital, Melbourne,
2Hospital Iturraspe, San ta Fe, Argentina
Australia.
Background: Historical evidence illustrates how Christofredo Jakob contributed to Neurosciences in Argentina. Method: Review of primary source documents from the XIX and X X centuries. Results: The most famous Argenrinian neurologist a n d the father of neuropsychiatry was Jos~ Maria R a m o s Mejia (1849-1914), "The R a m o s Mejia Hospital" perpetuates Iris name, one of his students was Jos~ A. Esttvez.Christofredo Jakob (1866-1956) was born in W~rnitz-Ostheim, G e r m a n y and h a d started Iris academic career under Adolf yon Stfftimpell's guidance. He lived and worked a lot in Argentina since 1889 up to his death. He was a great neuropathologist and from a neurobiological point o f view there are important papers of him dealing with the origin of the cerebral cortex from the striatum and the entortfinal areas. His students have been famous after lfim like Braulio M o y a n o and Vicente Dimitri, a pioneer in studies of the clinico-pathological correlations, who had visited European hospitals and became a very well-known professor of Neurology at the National University in 1941. Sturge-Weber syndrome has also been described as Sturge-Weber-Dimitri, because he h a d described previous cases in 1923. All of them were impressed and influenced by French Neurology. Conclusion: "To see in every day and year a symbol of all the days of m a n and his years, and convert the outrage of the years into a music., a sound, and a symbol..." Jorge Lnis Borges, The Hacedor
Aim: To review Australia's first intracranial meningioma resection; and to investigate the circumstances of the patient's death. Background: George Syme performed Australia's first documented meningioma resection in 1894 at St Vincent's Hospital, Melbourne. It followed Victor Horsley's first neurosurgical case by only 8 years. Although Syme's operation was successful, his patient died years later in unusual circumstances. Methods: The archives at St Vincent's Hospital, The Australasian College of Surgeons, and The Public Record Office Victoria were searched. The case notes by George Syme's assistant and the inquest proceedings into John Gleeson's death were examined. Results: A " t u m o u r the size of a tangerine orange" was removed from the left frontoparietal convexity of 30-year-old John Gleeson, a policeman. Gleeson presented with sensorimotor seizures before later developing symptoms of raised intracranial pressure. "rite patient recovered and his seizures resolved. In 1917 Gleeson died from an apparent gunshot to the head. A broken chair and a revolver were in the room. Gleeson's son h a d allegedly left the house earlier calling "that his father was shooting lfimself". The Coroner judged " t h a t the death (was) due to accident". Discussion: The operative notes reconfirm George Ssane's skill as a meticulous historian and surgeon. His pre-surgical localisation of the tumour is remarkable. The Coroner's decision does n o t appear to fully account for all the available testimony. Conclusion: George Syme performed a landmark operation 111 years ago on a y o u n g policeman whose later death adds an interesting epilogue to a piece o f Australian neurosurgical history.
0238 National Institute of Neurology, Russian Academy of Medical Sciences: 60 Years Suslina, Z 1, marioshkin, S z, Piradov, M a, Tanashyan, M 1. JNationa[ Institute of Neurology, P~ssian Academy of Medical Sciences, Ivloscow, Russia National Institute of Neurology of the Russian A c a d e m y of Medical Sciences was established on April 1, 1945. For 60 years it has been a leading research neurological institution in Russia and U S S R engaged in studies of most c o m m o n and severe diseases o f the nervous system. If was headed by brilliant neurologists N.Grashchenkov, N. Konovalov (student of a famous Russian neurologist Rossolimo), E. Shmidt, N. Vereshchagin. Just after the Second World War, research interests of the Institute were focused on traumatic injuries o f the head and nerves (as a consequence of the war). In the 1950s, the Institute was engaged in studies o f poliomyelitis, which resulted in creation of a s p edfic vaccine and virtual liquidation of the disease in U S S R (M.Tchumakov), as well as in the development of technologies of many-years artificial ventilation (L. Popova). Later, the Institute started research on cerebrovascular disorders, neurodegenerative disorders, neurogenetics and critical care in neurology. In amyotrophic lateral sclerosis, there is a well-known term " B u n i n a bodies", specific intraneuronal inclusions described in the 1960s by Dr. T. Bunina working in the Institute. Institute of Neurology m a d e significant contribution to studies of cerebrovascular disorders especially in the field of their hemorheologic and cardiac basis, Sneddoffs syndrome, problems of stroke heterogeneity, etc. Neurologists from the Institute described several new forms of hereditary neurological disorders and identified m u t a n t lod by linkage analysis. At present, the Institute is a regional W H O center in neurosciences coordinating research and educational activities in neurology in Russia and other countries of the CIS (former Soviet Union).
0239 "A twist in tile tale" of a surgeon and his patient
0241 Tile Billings Method - an Australian Neurologists story Tubridy, N ~. 1Department of Neurology, St. Vincent's University
Hospital, Ebn Park, Dublin d, Republic of Ireland Background: The Billings Ovulation Method of fanfily planning celebrated its 50± anniversary in 2003. The method is still practiced throughout the world today and was devised by Dr. JJ Billings a n d Iris wife Dr. Evelyn Billings in Melbourne, Australia. Dr. Billings was one of the first neurologists in Melbourne and was a pioneer in the field of Australian Neurology. Dr. Billings" extraordinary life a n d career is chronicled a n d h o w a single-handed neurologist aclfieved world renown in the field of family planning is discussed.
0242 MechatdmlS of myofascial trigger pOhlt Devlikamova, F. Kazan State Medical Academy, Department of
Neurology and Spinal Disorders, Kazan, Tatarstan, Russia Objectives: The aim o f this study was to evaluate the mechanisms of myofascial trigger point (TrP) formation. Methods: Sixteen patients with myofascial pain syndrome, caused by TrP in trapezius muscle, and 12 age-matched controls were included in this study. The trapezius muscle was examined by m e a n s of single fiber and concentric needle electrodes (Keypoint, Dante@ Muscle needle biopsies were studied by electron microscope. Results: The investigation showed changes in the shape of the main spike motor unit and endplate potentials, decrease in the duration and amplitude of motor unit potentials, increase in the duration and rise time endplate potentials in m y o f a s d a l TrP. In patients, the fibre density was increased in the TrP - 2.05, SD 0.26 [control- 1.48, SD 0.3; P < 0.01]. Mean values of consecutive differences o f the TrP is higher than that in control group. The destruction o f contractile apparatus that we observed involves myofibrils loss and broadened interfibrillar distance. In some parts of